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	题名	作者	年代	出处	被引量
1	Targeting Kupffer cells in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Why and how?显示文摘Mechanisms for non-alcoholic steatohepatitis(NASH)development are under investigation in an era of increased prevalence of obesity and metabolic syndrome. Previous findings have pointed to the role of adipose tissue, adipose tissue macrophages and their secretory products in the development of a chronic inflammatory status inducing insulin resistance and a higher risk of liver steatosis called non-alcoholic fatty liver disease. The activation of resident macrophages [Kupffer cells(KC)] and the recruitment of blood derived monocytes/macrophages into the diseased liver have now been identified as key elements for disease initiation and progression. Those cells could be activated through gut flora modifications and an altered gut barrier function but also through the internalization of toxic lipid compounds in adjacent hepatocytes or in KC themselves. Due to the role of activated KC in insulin resistance, fibrosis development and inflammation amplification, they became a target in clinical trials. A shift towards an anti-inflammatory KC phenotype through peroxisome proliferator activator-receptorδ agonists, an inhibition of macrophage recruitment through anti-C-C chemokine receptor 2 action and a specific blocking of internalization of toxic lipoxidation or glycation compounds into KC by galectin-3 receptor inhibitors are now under investigation in human NASH.	Nicolas Lanthier	2015	World Journal of Hepatology2015，7，19：	7
2	Adipose tissues as endocrine target organs显示文摘	Nicolas Lanthier Isabelle A. Leclercq	2014	Best Practice & Research Clinical Gastroenterology2014，，4：	2
3	Lack of electricity production by Pelobacter carbinolicus indicates that the capacity for Fe(Ⅲ) oxide reduction does not necessarily confer electron transfer ability to fuel cell anodes显示文摘	Richter H Lanthier M Nevin K P ct al	2007	Applied and Environmental Microbiology2007，73，16：	1
4	Nanomicellar formulation of coenzyme Q 10 (Ubisol-Q 10 ) effectively blocks ongoing neurodegeneration in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model: potential use as an adjuvant treatment in Parkinson’s disease显示文摘	Marianna Sikorska Patricia Lanthier Harvey Miller Melissa Beyers Caroline Sodja Bogdan Zurakowski Sandhya Gangaraju Siyaram Pandey Jagdeep K. Sandhu	2014	Neurobiology of Aging2014，，：	1
5	Development of a scal- able process for high yield leutiviral vector production by transient transfeetion of HEK293 suspension cultures 显示文摘	Ansorge S Lanthier S Transfiguracion J	2009	The journal of gene medicine2009，11，10：	1
6	Predictors of growth and distress following childhood parentification:A retrospective exploratory study显示文摘	Hooper LM Marotta SA Lanthier PP	2008	Journal of Child & Family Studies2008，17，5：	1
7	Skatole metabolism in theintact pre-pubescent male pig: The relationship between hepaticenzyme activity and skatole concentrations in plasma and fat显示文摘	Lanthier F Lou Y Squires E J	2007	Livestock Science2007，106，23：	1
8	Adipose tissues as endocrine targel organs 显示文摘	Lanthier N Leclereq IA	2014	Best Pract Res ClinGastroenterol2014，28，4：	1
9	Exacerbated susceptibility to infection-stimulated immunopathology in CD1d-deficient mice显示文摘	Smiley ST Lanthier PA Couper KN	2005	J Immunol2005，174，12：	1
10	The Role of the Diffusion of Oxygen and Radiation on the Spontaneous Combustibility of a Coal Pile in Confined Storage 显示文摘	Hull Ashley S Lanthier Jennifer L Chen Zumao	1997	Combustion and Flame1997，110，4：	1
11	Noninvasive monitoring of adrenocortical activity in carnivores by fecal glucocortieoid ana- lyses 显示文摘	Young K M Walker S L Lanthier C	2004	General and Comparative Endocrinology2004，137，2：	1
12	Evaluation of circadianvariation of blood pressure by ambulatory blood pressure monitoring inan elderly diabetic population with or without orthostatic hypotension显示文摘	Lanthier L Touchette M Bourget P	2011	Geriatr Psychol Neuropsychiatr Vieil2011，9，1：	1
13	Spectral analysis and acoustic transmission of mitral and aortic valve closure sounds indogs, Part 1 : Modelling the heart/thorax acoustic system显示文摘	DURAND LG LANGLOIS Y E LANTHIER T	1990	Ad Biol Eng Comput1990，28，：	1
14	Isolated angiitis of the CNS in children显示文摘	Lanthier S Lortie A Michaud J	2001	Neurology2001，56，：	1
15	Hepatic cell proliferation plays a pivotal role in the prognosis of alcoholic hepatitis显示文摘	Nicolas Lanthier Laura Rubbia-Brandt Nathalie Lin-Marq Sophie Clément Jean-Louis Frossard Nicolas Goossens Antoine Hadengue Laurent Spahr	2015	Journal of Hepatology2015，，3：	1
16	Proteomic analysis of Campylobacter jejuni 11168 biofilms reveals a role for the motility complex in biofilm formation 显示文摘	Kalmokoff M Lanthier P Tremblay T L	2006	J Bacteriol2006，188，：	1
17	Post-varicella arteriopathy of childhood显示文摘	Lanthier S Armstrong D Domi T	2005	Neurology2005，64，：	1
18	Parallel imple- mentation of geometric shortest path algorithms显示文摘	LANTHIER M NUSSBAUM D SACK J R	2003	Parallel Computing2003，29，10：	1
19	Predictors of growth and distress following childhood parentification:A retrospective exploratory study显示文摘	HOOPER L MAROTTA S LANTHIER R		0，，17：	1
20	Parallel imple- mentation of geometric shortest path algorithms显示文摘	LANTHIER M NUSSBAUM D SACK J R	2003	Parallel Computing2003，29，10：	1

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