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| 1 | 药物流出泵基因在白假丝酵母菌生物膜耐药性产生机制中的作用显示文摘目的利用药物流出泵基因缺陷株,初步阐明药物流出泵基因CDR1、CDR2、MDR1在生物膜耐药性产生和表现型耐药菌株产生中的作用。方法以3种咪唑类抗真菌药物以及CDR1药物流出泵抑制剂作用于药物流出泵基因缺陷株形成的生物膜,采用XTT法和菌落计数的方法,分析药物流出泵基因在生物膜耐药性产生中的作用。结果药物流出泵基因对缺陷株形成的24h生物膜SMIC80影响不大,生物膜表现型耐药株的产生与药物流出泵基因有关,抗真菌药物联合CDR1基因抑制剂在一定程度上能够帮助杀灭白假丝酵母菌生物膜耐药株。结论药物流出泵基因对24h生物膜表现出来的耐药性影响不大,而对生物膜产生的耐药株有重要作用。 | 亓庆国 Micheal. D. Lafleur | 2009 | 华西口腔医学杂志2009，27，2： | 6 |
| 2 | Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression显示文摘 | Victoria G Weis Josane F Sousa Bonnie J LaFleur Ki Taek Nam Jared A Weis Paul E Finke Nadia A Ameen James G Fox James R Goldenring | 2013 | Gut2013，，9： | 3 |
| 3 | Absolute and relative contraindications to pegylated‐interferon or ribavirin in the US general patient population with chronic hepatitis C: results from a US database of over 45 000 HCV ‐infected, evaluated patients显示文摘 | A. H. Talal J. LaFleur R. Hoop P. Pandya P. Martin I. Jacobson J. Han E. J. Korner | 2013 | Aliment Pharmacol Ther2013，，4： | 2 |
| 4 | Quadcopter control in three-dimensional space using a noninvasive motor imagery-based brain-computer interface 显示文摘 | LaFleur K Cassady K Doud A | 2013 | Journal of Neural Engineering2013，10，04： | 1 |
| 5 | Interleukin(IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells显示文摘 | Lafleur E A Jia S F Worth L L | 2001 | Cancer Res2001，61，10： | 1 |
| 6 | Candida albicans biofilms produce antifungal-tolerant persister cel s显示文摘 | LaFleur MD Kumamoto CA Lewis K | | 0，，11： | 1 |
| 7 | Polyamines are oncometab-olites that regulate the LIN28/let-7 pathway in colorectalcancer cells显示文摘 | Paz EA LaFleur B Gerner EW | 2014 | Mol Carcinog2014，531，： | 1 |
| 8 | Comparison of the struc-ture and the transport properties of low-set and high-set curdlanhydrogels显示文摘 | Marc-AndréGagnon Michel Lafleur | 2011 | Journal of Colloid and interface Science2011，357，： | 1 |
| 9 | Candida albicans biofilms produce antifungal-tolerant persiser cells 显示文摘 | LaFleur MD Kumamoto CA Lewis K | 2006 | Antimicrob Agents Chemother2006，50，11： | 1 |
| 10 | Annual cycle of CO2 exchange at a bog peafland 显示文摘 | Lafleur P M Roulet N T Admiral S W | 2001 | Journal of Geophysical Research Atmospheres2001，106，3： | 1 |
| 11 | Fas expression inversely correlates with metastatic potential in osteosarcoma cells 显示文摘 | Worth LL Lafleur EA Jia SF | 2002 | Oncol Rep2002，9，4： | 1 |
| 12 | Evidence that badnavirus infection in Musa can originate from integrated pararetroviral sequences显示文摘 | Ndowora T Dahala G LaFleur D | 1999 | Virology1999，255，2： | 1 |
| 13 | Human cell mutagenicity of oxygenated,nitrated and unsubstituted polycyclic aromatic hydrocarbons associated with urban aerosols显示文摘 | DURANT J L BUSBY JR W F LAFLEUR A L | 1996 | Mutat Res Gen Tox1996，371，： | 1 |
| 14 | Potential role of mental practice using motor imagery in neurologic rehabilitation显示文摘 | Jackson PL Lafleur MF Malouin F | | 0，，： | 1 |
| 15 | A study of heat transfer in the blown film process显示文摘 | Zhang Z Lafleur P G | 2007 | Journal of Plastic Film and Sheeting2007，23，4： | 1 |
| 16 | Seasonal trends in energy,water,and carbon dioxide fluxes at a northern boreal wetland显示文摘 | Lafleur PM McCaughey JH JoiER DW etyal | 1997 | Journal of Geophysical Research1997，102，29： | 1 |
| 17 | The type 1 collagen induction of MT1-MMP-mediated MMP-2activation is repreased by alpha Vbeta3 integrin in humanbreast cancer cells显示文摘 | BORRIRUKWANIT K LAFLEUR M A MERCURI F A | 2007 | Matrix Biology2007，26，4： | 1 |
| 18 | Thermal decomposition of va- rious alkyl onium organoclays: Effect on polyethylene terephthalate nanocomposites properties显示文摘 | Stoeffler K Lafleur P G Denault J | 2008 | Polym Degradation Stability2008，93，7： | 1 |
| 19 | Self-diffusion of macromolecules and macroassemblies in curdlan gels as examined by PFG-SE NMR technique显示文摘 | Kwak S Lafleur M | 2003 | Colloids and Surfaces a-Physicochemical and Engineering Aspects2003，221，123： | 1 |
| 20 | Magnitudes and seasonal patterns of energy, ater, and carbon exchanges at a boreal young jack pine forest in the BOREAS northern study area显示文摘 | Mccaughey J H Lafleur P M Joiner D W | 1997 | J Geophys Res1997，102，24： | 1 |
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