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628篇 您的检索式:作者名="Krishna G"
    题名 作者 年代 出处 被引量
1健康受试者不同胃部状态下泊沙康唑口服混悬剂的药动学研究显示文摘Krishna G Moton A 陈喆焱 汪复 2009中国感染与化疗杂志2009,9,5:22
2Information asymmetry, corporate disclosure, and the capital markets: A review of the empirical disclosure literature显示文摘Paul M Healy Krishna G Palepu 2001Journal of Accounting and Economics2001,,1:14
3Information asymmetry, corporate disclosure, and the capital markets: A review of the empirical disclosure literature显示文摘Paul M Healy Krishna G Palepu 2001Journal of Accounting and Economics2001,,1:4
4Appraisal of needle-based confocal laser endomicroscopy inthe diagnosis of pancreatic cysts显示文摘Nearly 2.5% of cross-sectional imaging studies will report a finding of a cystic pancreatic lesion. Eventhough most of these are incidental findings, it remains very concerning for both patients and treating clinicians. Differentiating and predicting malignant transformation in pancreatic cystic lesions is clinically challenging. Current evaluation of suspicious cystic lesions includes a combination of radiologic imaging, endoscopic ultrasound(EUS) and cyst fluid analyses. Despite these attempts, precise diagnostic stratification among nonmucinous, mucinous, and malignant cystic lesions is often not possible until surgical resection. EUS-guided needle based confocal laser endomicroscopy(n CLE) for evaluation of pancreatic cysts is emerging as a powerful technique with remarkable potential. Though limited imaging data from 3 large clinical trials(INSPECT, DETECT and CONTACT) are currently the reference standard for n CLE imaging, nonetheless these have not been validated in large studies. The aim of this review article is to review the evolving role of EUS-guided n CLE in management of pancreatic cystic lesions in terms of its significance, adverse events, limitations, and implications.Somashekar G Krishna Jeffery H Lee 2016World Journal of Gastroenterology2016,22,4:4
5Recent advances in the diagnostic evaluation of pancreatic cystic lesions显示文摘Pancreatic cystic lesions(PCLs)are becoming more prevalent due to more frequent abdominal imaging and the increasing age of the general population.It has become crucial to identify these PCLs and subsequently risk stratify them to guide management.Given the high morbidity associated with pancreatic surgery,only those PCLs at high risk for malignancy should undergo such treatment.However,current diagnostic testing is suboptimal at accurately diagnosing and risk stratifying PCLs.Therefore,research has focused on developing new techniques for differentiating mucinous from non-mucinous PCLs and identifying high risk lesions for malignancy.Cross sectional imaging radiomics can potentially improve the predictive accuracy of primary risk stratification of PCLs at the time of detection to guide invasive testing.While cyst fluid glucose has reemerged as a potential biomarker,cyst fluid molecular markers have improved accuracy for identifying specific types of PCLs.Endoscopic ultrasound guided approaches such as confocal laser endomicroscopy and through the needle microforceps biopsy have shown a good correlation with histopathological findings and are evolving techniques for identifying and risk stratifying PCLs.While most of these recent diagnostics are only practiced at selective tertiary care centers,they hold a promise that management of PCLs will only get better in the future.Devarshi R Ardeshna Troy Cao Brandon Rodgers Chidiebere Onongaya Dan Jones Wei Chen Eugene J Koay Somashekar G Krishna 2022World Journal of Gastroenterology2022,28,6:3
6Confocal endomicroscopy and cyst fluid molecular analysis: Comprehensive evaluation of pancreatic cysts显示文摘Increases in the quality as well as utilization of cross-sectional imaging have led to rising diagnoses of pancreatic cystic lesions(PCL). Accurate presurgical diagnosis enables appropriate triage of PCLs. Unfortunately, current diagnostic approaches have suboptimal accuracy and may lead to unnecessary surgical resections or missed diagnoses of advanced neoplasia. Additionally, early detection represents an opportunity for intervention to prevent the progression to pancreatic adenocarcinoma. Our aim for this review is to systematically review the current literature on confocal endomicroscopy and molecular biomarkers in the evaluation of PCLs. Confocal laser endomicroscopy is a novel technology that allows for real-time in vivo microscopic imaging with multiple clinical trials identifying characteristic endomicroscopy findings of various pancreatic cystic lesions. DNA-based molecular markers have also emerged as another diagnostic modality as the pattern of genetic alternations present in cyst fluid can provide both diagnostic and prognostic data. We propose that both techniques can be utilized to improve patient outcomes.Feng Li Ahmad Malli Zobeida Cruz-Monserrate Darwin L Conwell Somashekar G Krishna 2018World Journal of Gastrointestinal Endoscopy2018,10,1:2
7Extrahepatic metastasis of hepatocellular carcinoma to the paravertebral muscle:A case report显示文摘Identification of extrahepatic metastases(EHM) of hepatocellular carcinoma(HCC) has been paradoxically increasing due to an increase in the survival of HCC patients. However, metastasis of HCC to the skeletal muscle tissue is extremely rare. We describe a unique case of HCC metastasizing to the paravertebral muscle. A 55-year-old man with a history of hepatitis B cirrhosis underwent partial liver resection with complete removal of HCC. Three months later, a computed tomography(CT) scan showed intrahepatic recurrence. The tumors were treated with yttrium-90 microspheres, transcatheter arterial chemoembolization, and sorafenib. Six months later, a CT scan showed an enhancing lesion of the left paravertebral muscle that on biopsy were consistent with metastatic HCC. The tumor was treated with stereotactic hypo-fractionated imageguided radiation therapy(SHFRT). A follow-up scan 3 mo post-radiotherapy revealed a stable appearance of the paravertebral muscle metastasis. Because of the progression in the intrahepatic tumors, the patient was treated with capecitabine, which was changed to dasatinib 6 mo later. The patient passed away three years after the primary surgical resection. Management of EHM poses an extreme challenge. This is the first case of HCC with EHM to the paravertebral muscle in which stability of disease was achieved using SHFRT. This case highlights the importance of early detection of hepatitis B viral infection and initiation of anti-viral therapy to decrease recurrence of HCC and prevent EHM.Kazuhiro Takahashi Krishna G Putchakayala Mohamed Safwan Dean Y Kim 2017World Journal of Hepatology2017,9,22:2
8Analysis of driveline loads in an automotive powertrain with multiple Cardan joints显示文摘Krishna V Naganathan N G Phaduis R 2000Journal of Autombile Engineering2000,214,:2
9Analysis of driveline loads in an automotive power train with multiple Cardan joints 显示文摘Krishna V Naganathan N G Phadnis R 2000Proc Inst Mech Eng Part D J Automob Eng2000,214,5:2
10Advanced diagnostics for pancreatic cysts: Confocal endomicroscopy and molecular analysis显示文摘Technological advances and the widespread use of medical imaging have led to an increase in the identification of pancreatic cysts in patients who undergo crosssectional imaging. Current methods for the diagnosis and risk-stratification of pancreatic cysts are suboptimal, resulting in both unnecessary surgical resection and overlooked cases of neoplasia. Accurate diagnosis is crucial for guiding how a pancreatic cyst is managed, whether with surveillance for low-risk lesions or surgical resection for high-risk lesions. This review aims to summarize the current literature on confocal endomicroscopy and cyst fluid molecular analysis for the evaluation of pancreatic cysts. These recent technologies are promising adjuncts to existing approaches with the potential to improve diagnostic accuracy and ultimately patient outcomes.Claire Durkin Somashekar G Krishna 2019World Journal of Gastroenterology2019,25,22:2
111-Hexene isomerization and n-hexane cracking over HMCM-22显示文摘ANUP K T KRISHNA G B TOSHIHIDE B 2001Applied Catalysis A:General2001,213,2:1
12Effects of age, gender and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers 显示文摘Sansone- Parsons A Krishna G Simon J 2007Antimicrob Agents Chemother2007,51,2:1
13A novel self emulsifying parenteral drug delivery system显示文摘Krishna G Sheth BB 1999PDA J Pharm Sci Technol1999,53,4:1
14Surface and Coatings Technology 显示文摘Sundararajan G Rama Krishna L 2003167:2692003,167,:1
15DNA isolation from single or half seeds suitable for random amplified polymorphic DNA analyses显示文摘Krishna T G Jawali N 0,,1:1
16pb( II ) uptake by kaolinite and montorrillonite in aqueous medium显示文摘Krishna G B Susmita S G 2006Colloids and Surfaces A2006,277,13:1
17Assessment of uterine cavity by hysteroscopy in assisted reproduction progamme and its itffluence on pregnancy outcome显示文摘Rama Raju GA Shashi Kumarei G Krishna KM 2006Arch Gynecol Obstet2006,274,1:1
18Circadian rhythm of intraocular pressure: a rat model 显示文摘Krishna R Mermoud A Baerreldt G 1995Ophthalmic Res1995,27,:1
19Treatment of low- strength soluble wastewater using an anaerobic baffled reactor (ABR) 显示文摘Gopala Krishna G V T Kumarb P Kumarb P 2009Journal of Environmental Management2009,90,1:1
20Managing cross-cultural issues in global software outsourcing 显示文摘Krishna S Sahay S Walsham G 2004Communications of the ACM2004,47,4:1
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