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| 1 | 健康受试者不同胃部状态下泊沙康唑口服混悬剂的药动学研究显示文摘 | Krishna G Moton A 陈喆焱 汪复 | 2009 | 中国感染与化疗杂志2009,9,5: | 22 |
| 2 | Information asymmetry, corporate disclosure, and the capital markets: A review of the empirical disclosure literature显示文摘 | Paul M Healy Krishna G Palepu | 2001 | Journal of Accounting and Economics2001,,1: | 14 |
| 3 | Information asymmetry, corporate disclosure, and the capital markets: A review of the empirical disclosure literature显示文摘 | Paul M Healy Krishna G Palepu | 2001 | Journal of Accounting and Economics2001,,1: | 4 |
| 4 | Appraisal of needle-based confocal laser endomicroscopy inthe diagnosis of pancreatic cysts显示文摘Nearly 2.5% of cross-sectional imaging studies will report a finding of a cystic pancreatic lesion. Eventhough most of these are incidental findings, it remains very concerning for both patients and treating clinicians. Differentiating and predicting malignant transformation in pancreatic cystic lesions is clinically challenging. Current evaluation of suspicious cystic lesions includes a combination of radiologic imaging, endoscopic ultrasound(EUS) and cyst fluid analyses. Despite these attempts, precise diagnostic stratification among nonmucinous, mucinous, and malignant cystic lesions is often not possible until surgical resection. EUS-guided needle based confocal laser endomicroscopy(n CLE) for evaluation of pancreatic cysts is emerging as a powerful technique with remarkable potential. Though limited imaging data from 3 large clinical trials(INSPECT, DETECT and CONTACT) are currently the reference standard for n CLE imaging, nonetheless these have not been validated in large studies. The aim of this review article is to review the evolving role of EUS-guided n CLE in management of pancreatic cystic lesions in terms of its significance, adverse events, limitations, and implications. | Somashekar G Krishna Jeffery H Lee | 2016 | World Journal of Gastroenterology2016,22,4: | 4 |
| 5 | Recent advances in the diagnostic evaluation of pancreatic cystic lesions显示文摘Pancreatic cystic lesions(PCLs)are becoming more prevalent due to more frequent abdominal imaging and the increasing age of the general population.It has become crucial to identify these PCLs and subsequently risk stratify them to guide management.Given the high morbidity associated with pancreatic surgery,only those PCLs at high risk for malignancy should undergo such treatment.However,current diagnostic testing is suboptimal at accurately diagnosing and risk stratifying PCLs.Therefore,research has focused on developing new techniques for differentiating mucinous from non-mucinous PCLs and identifying high risk lesions for malignancy.Cross sectional imaging radiomics can potentially improve the predictive accuracy of primary risk stratification of PCLs at the time of detection to guide invasive testing.While cyst fluid glucose has reemerged as a potential biomarker,cyst fluid molecular markers have improved accuracy for identifying specific types of PCLs.Endoscopic ultrasound guided approaches such as confocal laser endomicroscopy and through the needle microforceps biopsy have shown a good correlation with histopathological findings and are evolving techniques for identifying and risk stratifying PCLs.While most of these recent diagnostics are only practiced at selective tertiary care centers,they hold a promise that management of PCLs will only get better in the future. | Devarshi R Ardeshna Troy Cao Brandon Rodgers Chidiebere Onongaya Dan Jones Wei Chen Eugene J Koay Somashekar G Krishna | 2022 | World Journal of Gastroenterology2022,28,6: | 3 |
| 6 | Confocal endomicroscopy and cyst fluid molecular analysis: Comprehensive evaluation of pancreatic cysts显示文摘Increases in the quality as well as utilization of cross-sectional imaging have led to rising diagnoses of pancreatic cystic lesions(PCL). Accurate presurgical diagnosis enables appropriate triage of PCLs. Unfortunately, current diagnostic approaches have suboptimal accuracy and may lead to unnecessary surgical resections or missed diagnoses of advanced neoplasia. Additionally, early detection represents an opportunity for intervention to prevent the progression to pancreatic adenocarcinoma. Our aim for this review is to systematically review the current literature on confocal endomicroscopy and molecular biomarkers in the evaluation of PCLs. Confocal laser endomicroscopy is a novel technology that allows for real-time in vivo microscopic imaging with multiple clinical trials identifying characteristic endomicroscopy findings of various pancreatic cystic lesions. DNA-based molecular markers have also emerged as another diagnostic modality as the pattern of genetic alternations present in cyst fluid can provide both diagnostic and prognostic data. We propose that both techniques can be utilized to improve patient outcomes. | Feng Li Ahmad Malli Zobeida Cruz-Monserrate Darwin L Conwell Somashekar G Krishna | 2018 | World Journal of Gastrointestinal Endoscopy2018,10,1: | 2 |
| 7 | Extrahepatic metastasis of hepatocellular carcinoma to the paravertebral muscle:A case report显示文摘Identification of extrahepatic metastases(EHM) of hepatocellular carcinoma(HCC) has been paradoxically increasing due to an increase in the survival of HCC patients. However, metastasis of HCC to the skeletal muscle tissue is extremely rare. We describe a unique case of HCC metastasizing to the paravertebral muscle. A 55-year-old man with a history of hepatitis B cirrhosis underwent partial liver resection with complete removal of HCC. Three months later, a computed tomography(CT) scan showed intrahepatic recurrence. The tumors were treated with yttrium-90 microspheres, transcatheter arterial chemoembolization, and sorafenib. Six months later, a CT scan showed an enhancing lesion of the left paravertebral muscle that on biopsy were consistent with metastatic HCC. The tumor was treated with stereotactic hypo-fractionated imageguided radiation therapy(SHFRT). A follow-up scan 3 mo post-radiotherapy revealed a stable appearance of the paravertebral muscle metastasis. Because of the progression in the intrahepatic tumors, the patient was treated with capecitabine, which was changed to dasatinib 6 mo later. The patient passed away three years after the primary surgical resection. Management of EHM poses an extreme challenge. This is the first case of HCC with EHM to the paravertebral muscle in which stability of disease was achieved using SHFRT. This case highlights the importance of early detection of hepatitis B viral infection and initiation of anti-viral therapy to decrease recurrence of HCC and prevent EHM. | Kazuhiro Takahashi Krishna G Putchakayala Mohamed Safwan Dean Y Kim | 2017 | World Journal of Hepatology2017,9,22: | 2 |
| 8 | Analysis of driveline loads in an automotive powertrain with multiple Cardan joints显示文摘 | Krishna V Naganathan N G Phaduis R | 2000 | Journal of Autombile Engineering2000,214,: | 2 |
| 9 | Analysis of driveline loads in an automotive power train with multiple Cardan joints 显示文摘 | Krishna V Naganathan N G Phadnis R | 2000 | Proc Inst Mech Eng Part D J Automob Eng2000,214,5: | 2 |
| 10 | Advanced diagnostics for pancreatic cysts: Confocal endomicroscopy and molecular analysis显示文摘Technological advances and the widespread use of medical imaging have led to an increase in the identification of pancreatic cysts in patients who undergo crosssectional imaging. Current methods for the diagnosis and risk-stratification of pancreatic cysts are suboptimal, resulting in both unnecessary surgical resection and overlooked cases of neoplasia. Accurate diagnosis is crucial for guiding how a pancreatic cyst is managed, whether with surveillance for low-risk lesions or surgical resection for high-risk lesions. This review aims to summarize the current literature on confocal endomicroscopy and cyst fluid molecular analysis for the evaluation of pancreatic cysts. These recent technologies are promising adjuncts to existing approaches with the potential to improve diagnostic accuracy and ultimately patient outcomes. | Claire Durkin Somashekar G Krishna | 2019 | World Journal of Gastroenterology2019,25,22: | 2 |
| 11 | 1-Hexene isomerization and n-hexane cracking over HMCM-22显示文摘 | ANUP K T KRISHNA G B TOSHIHIDE B | 2001 | Applied Catalysis A:General2001,213,2: | 1 |
| 12 | Effects of age, gender and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers 显示文摘 | Sansone- Parsons A Krishna G Simon J | 2007 | Antimicrob Agents Chemother2007,51,2: | 1 |
| 13 | A novel self emulsifying parenteral drug delivery system显示文摘 | Krishna G Sheth BB | 1999 | PDA J Pharm Sci Technol1999,53,4: | 1 |
| 14 | Surface and Coatings Technology 显示文摘 | Sundararajan G Rama Krishna L | 2003 | 167:2692003,167,: | 1 |
| 15 | DNA isolation from single or half seeds suitable for random amplified polymorphic DNA analyses显示文摘 | Krishna T G Jawali N | | 0,,1: | 1 |
| 16 | pb( II ) uptake by kaolinite and montorrillonite in aqueous medium显示文摘 | Krishna G B Susmita S G | 2006 | Colloids and Surfaces A2006,277,13: | 1 |
| 17 | Assessment of uterine cavity by hysteroscopy in assisted reproduction progamme and its itffluence on pregnancy outcome显示文摘 | Rama Raju GA Shashi Kumarei G Krishna KM | 2006 | Arch Gynecol Obstet2006,274,1: | 1 |
| 18 | Circadian rhythm of intraocular pressure: a rat model 显示文摘 | Krishna R Mermoud A Baerreldt G | 1995 | Ophthalmic Res1995,27,: | 1 |
| 19 | Treatment of low- strength soluble wastewater using an anaerobic baffled reactor (ABR) 显示文摘 | Gopala Krishna G V T Kumarb P Kumarb P | 2009 | Journal of Environmental Management2009,90,1: | 1 |
| 20 | Managing cross-cultural issues in global software outsourcing 显示文摘 | Krishna S Sahay S Walsham G | 2004 | Communications of the ACM2004,47,4: | 1 |