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| 1 | Intravenous vitamin C as adjunctive therapy for enterovirus/rhinovirus induced acute respiratory distress syndrome显示文摘We report a case of virus-induced acute respiratory distress syndrome(ARDS) treated with parenteral vitamin C in a patient testing positive for enterovirus/rhinovirus on viral screening. This report outlines the first use of high dose intravenous vitamin C as an interventional therapy for ARDS, resulting from enterovirus/rhinovirus respiratory infection. From very significant preclinical research performed at Virginia Commonwealth Universitywith vitamin C and with the very positive results of a previously performed phase Ⅰ safety trial infusing high dose vitamin C intravenously into patients with severe sepsis, we reasoned that infusing identical dosing to a patient with ARDS from viral infection would be therapeutic. We report here the case of a 20-year-old, previously healthy, female who contracted respiratory enterovirus/rhinovirus infection that led to acute lung injury and rapidly to ARDS. She contracted the infection in central Italy while on an 8-d spring break from college. During a return flight to the United States, she developed increasing dyspnea and hypoxemia that rapidly developed into acute lung injury that led to ARDS. When support with mechanical ventilation failed, extracorporeal membrane oxygenation(ECMO) was initiated. Twelve hours following ECMO initiation, high dose intravenous vitamin C was begun. The patient's recovery was rapid. ECMO and mechanical ventilation were discontinued by day-7 and the patient recovered with no long-term ARDS sequelae. Infusing high dose intravenous vitamin C into this patient with virus-induced ARDS was associated with rapid resolution of lung injury with no evidence of post-ARDS fibroproliferative sequelae. Intravenous vitamin C as a treatment for ARDS may open a new era of therapy for ARDS from many causes. | Alpha A Fowler Ⅲ Christin Kim Lawrence Lepler Rajiv Malhotra Orlando Debesa Ramesh Natarajan Bernard J Fisher Aamer Syed Christine DeWilde Anna Priday Vigneshwar Kasirajan | 2017 | World Journal of Critical Care Medicine2017，6，1： | 9 |
| 2 | 药用植物内生菌对作物生长及氧化应激的作用(英文)显示文摘目的:探讨药用植物内生菌的多样性及其在种子生长和氧化应激中的作用。方法:从三种药用植物(Caralluma acutangula、Rhazya stricta和Moringa peregrina)中提取内生菌;基于18S r DNA测序和系统发育分析鉴定分离得到的内生菌株;以正常和矮化突变体水稻品系为对照,比较不同浓度的内生菌培养滤液(CF)对水稻种子的发芽和生长的影响;通过气相色谱-质谱分析CF中的有效活性成分。结论:从药用植物中共获得10种内生菌,包括茎点霉属6株、链格孢属2株、双极霉属1株和枝孢霉属1株。CF表现出剂量依赖性的生长刺激和抑制作用。与对照和其他内生菌相比,100%的茎点霉菌CF显著促进了水稻种子的发芽和生长;双极霉中的吲哚乙酸含量最高,并表现出比其更高的自由基清除和抗脂质过氧化活性;双极霉菌和茎点霉菌的类黄酮和酚类成分较高。综上所述,药用植物中存在内生菌株,其可以用于改善作物生长和减轻氧化应激。 | Abdul Latif KHAN Syed Abdullah GILANI Muhammad WAQAS Khadija AL-HOSNI Salima AL-KHIZIRI Yoon-Ha KIM Liaqat ALI Sang-Mo KANG Sajjad ASAF Raheem SHAHZAD Javid HUSSAIN In-Jung LEE Ahmed AL-HARRASI | 2017 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2017，18，2： | 6 |
| 3 | Drug eluting biliary stents to decrease stent failure rates:Areview of the literature显示文摘Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy. | Joseph Shatzel Jisoo Kim Kartik Sampath Sharjeel Syed Jennifer Saad Zilla H Hussain Kabir Mody J Marc Pipas Stuart Gordon Timothy Gardner Richard I Rothstein | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，2： | 6 |
| 4 | A Multicenter Analysis of Distal Pancreatectomy for Adenocarcinoma: Is Laparoscopic Resection Appropriate?显示文摘 | David A. Kooby William G. Hawkins C. Max Schmidt Sharon M. Weber David J. Bentrem Theresa W. Gillespie Johnita Byrd Sellers Nipun B. Merchant Charles R. Scoggins Robert C.G. Martin Hong Jin Kim Syed Ahmad Clifford S. Cho Alexander A. Parikh Carrie K. Chu | 2010 | Journal of the American College of Surgeons2010，，5： | 2 |
| 5 | Rational Design and Application of an Indolium-Derived Heptamethine Cyanine with Record-Long Second Near-Infrared Emission显示文摘Heptamethine cyanine dyes,typified by indocyanine green,have been extensively employed as bioimaging indicators and theranostic agents.Significant efforts have been made to develop functional heptamethine cyanine dyes with outstanding bioimaging and theranostic utilities.In this work,we rationally designed and successfully developed a novel indolium-like heptamethine cyanine dye by installing indolium-derived polycyclic aromatic hydrocarbons on the terminal ends of a conjugated polyene backbone.This dye showed excellent photostability and showed bright fluorescent emission in the second near-infrared(NIR-Ⅱ)window with a peak at approximately 1120 nm.Such long wavelength emission prompted a superior bioimaging resolution in vivo.In particular,this NIR-Ⅱ dye had the remarkable capability of marking the blood vessels of the hindlimbs,abdomens,and brains of mice.More significantly,this dye involved a typical indolium-like heptamethine skeleton and exhibited two strong absorption bands in the 700–1300 nm NIR range,which endowed it with an intrinsic tumor-targeting capability and a high photothermal conversion efficiency(up to 68.2%),serving for the photothermal therapy of tumors under the guidance of NIR-Ⅱ fluorescence imaging.This work provides an efficient design strategy for achieving indolium-like heptamethine cyanine dyes with further NIR-Ⅱ emission. | Xiaoxie Ma Yurou Huang Syed Ali Abbas Abedi Heejeong Kim Tan Teck Boon Davin Xiaogang Liu Wen-Chao Yang Yao Sun Sheng Hua Liu Jun Yin Juyoung Yoon Guang-Fu Yang | 2022 | CCS Chemistry2022，4，6： | 2 |
| 6 | Left-sided Pancreatectomy: A Multicenter Comparison of Laparoscopic and Open Approaches显示文摘 | David A. Kooby Theresa Gillespie David Bentrem Attila Nakeeb Max c. Schmidt Nipun B. Merchant Alex A. Parikh Robert C. G. Martin Charles R. Scoggins Syed Ahmad Hong Jin Kim Jaemin Park Fabian Johnston Matthew J. Strouch Alex Menze Jennifer Rymer Rebecca M | 2008 | Annals of Surgery2008，，3： | 2 |
| 7 | 支气管肺泡灌洗和支气管冲洗对痰少或痰涂片阴性疑似肺结核的诊断价值:一项随机研究显示文摘背景高质量的呼吸道标本对准确早期诊断肺结核很重要。但是,目前以痰液作为标本的直接镜检、培养和核酸扩增试验敏感度相对较差。大部分肺结核患者痰液较少或者痰液结核分枝杆菌检测呈阴性。目的对于疑似肺结核但痰液稀少或痰涂片阴性的患者,支气管肺泡灌洗(BAL)和支气管冲洗(BW)是两种主要的检查方法,可以获取高质量的呼吸道样本。本研究的目标是比较BAL和BW对此类患者的诊断价值。 | Kim YW Kwon BS Lim SY 卫卫 姚岚 | 2019 | 结核病与肺部健康杂志2019，8，4： | 2 |
| 8 | Intelligent Islanding Detection of Multi-distributed Generation Using Artificial Neural Network Based on Intrinsic Mode Function Feature显示文摘The integration of distributed energy resources(DERs) into distribution networks is becoming increasingly important, as it supports the continued adoption of renewable power generation, combined heat and power plants, and storage systems. Nevertheless, inadvertent islanding operation is one of the major protection issues in distribution networks connected to DERs. This study proposes an intelligent islanding detection method(IIDM) using an intrinsic mode function(IMF)feature-based grey wolf optimized artificial neural network(GWO-ANN). In the proposed IIDM, the modal voltage signal is pre-processed by variational mode decomposition followed by Hilbert transform on each IMF to derive highly involved features. Then, the energy and standard deviation of IMFs are employed to train/test the GWO-ANN model for identifying the islanding operations from other non-islanding events. To evaluate the performance of the proposed IIDM, various islanding and non-islanding conditions such as faults, voltage sag, linear and nonlinear load and switching, are considered as the training and testing datasets. Moreover, the proposed IIDM is evaluated under noise conditions for the measured voltage signal. The simulation results demonstrate that the proposed IIDM is capable of differentiating between islanding and non-islanding events without any sensitivity under noise conditions in the test signal. | Samuel Admasie Syed Basit Ali Bukhari Teke Gush Raza Haider Chul Hwan Kim | 2020 | Journal of Modern Power Systems and Clean Energy2020，8，3： | 2 |
| 9 | Recombinant Paragonimus westermani yolk ferritin is a useful serodiagnostic antigen 显示文摘 | Kim TY Joo IJ Kang SY | 2002 | J Infect Dis2002，185，9： | 2 |
| 10 | Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas 显示文摘 | Soung YH Lee JW Kim SY | 2005 | Virchows Arch2005，446，5： | 1 |
| 11 | Immunohistochemical study of central neurocytoma, subependymoma,and subependymal giant cell astrocytoma显示文摘 | You H Kim YI Im SY | 2005 | J Neurooncol2005，74，1： | 1 |
| 12 | Binding aspects of baicalein to HIV-1 integrase显示文摘 | Ahn HC Lee SY Kim JW | 2001 | Mol Cells2001，12，1： | 1 |
| 13 | The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model 显示文摘 | Lira SY Kim YS Ahn Y | 2006 | Cardiovasc Res2006，70，3： | 1 |
| 14 | CHOP followed by involvedfield radiation: is it optimal for localized nasal natural killer/T-cell lymphoma显示文摘 | Kim WS Song SY Ahn YC | 2001 | Ann Oncol2001，12，3： | 1 |
| 15 | A Handwritten Numeral Character Classification Using Tolerant Rough Set显示文摘 | Bang SY | 2000 | IEEE Trans on Pattern Analysis and Machine Intelligence2000，22，9： | 1 |
| 16 | Dicer is essential for mouse development 显示文摘 | Benrstein E Kim SY Carmell MA Murchison EP Alcorn H Li MZ | 2003 | Nat Genet2003，35，3： | 1 |
| 17 | A case of multiple metastatic low-grade endometrial stromal sarcoma arising from an ovarian endometriotic lesion显示文摘 | Kim JY Hong SY Sung HJ | 2009 | J Gynecol Oncol2009，20，2： | 1 |
| 18 | IL-23R polymorphisms in patients with ankylosing spondylitis in Korea显示文摘 | Sung IH Kim TH Bang SY | 2009 | J Rheumatol2009，36，5： | 1 |
| 19 | Prevalence and risk of colorectal adenoma in asymptomatic Koreans aged 40-49 years undergoing screening colonoscopy显示文摘 | Chung SJ Kim YS Yang SY | 2010 | J Gastroenterol Hepatol2010，25，3： | 1 |
| 20 | Effects of beta-toxin of Staphylococcus aureus on ciliary activity of nasal epithelial cells显示文摘 | Kim CS Jean SY Min YG | 2000 | Laryngoscope2000，110，12： | 1 |
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