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| 1 | Revisions to the Tumor,Node,Metastasis staging of lung cancer(8th edition):Rationale,radiologic findings and clinical implications显示文摘The Tumor, Node, Metastasis(TNM) staging system,adopted by the Union for International Cancer Control(UICC) and the American Joint Committee on Cancer(AJCC), has been recently revised, with the new 8^(th) edition of the staging manual being published in January 2017. This edition has few but important evidencebased changes to the TNM staging system used for lung cancer. Radiologists should be aware of the updated classification system to accurately provide staging information to oncologists and oncosurgeons. In this article, we discuss the rationale, illustrate the changes with relevance to Radiology, and review the clinical implications of the 8^(th) edition of the UICC/AJCC TNM staging system with regards to lung cancer. | Fernando U Kay Asha Kandathil Kiran Batra Sachin S Saboo Suhny Abbara Prabhakar Rajiah | 2017 | World Journal of Radiology2017，9，6： | 39 |
| 2 | Electro-acupuncture to prevent prolonged postoperative ileus:A randomized clinical trial显示文摘AIM:To examine whether acupuncture can prevent prolonged postoperative ileus(PPOI)after intraperitoneal surgery for colon cancer. METHODS:Ninety patients were recruited from the Fudan University Cancer Hospital,Shanghai,China. After surgery,patients were randomized to receive acupuncture(once daily,starting on postoperative day 1, for up to six consecutive days)or usual care.PPOI was defined as an inability to pass flatus or have a bowel movement by 96 h after surgery.The main outcomes were time to first flatus,time to first bowel movement, and electrogastroenterography.Secondary outcomes were quality of life(QOL)measures,including pain, nausea,insomnia,abdominal distension/fullness,and sense of well-being. RESULTS:No significant differences in PPOI on day 4 (P=0.71)or QOL measures were found between the groups.There were also no group differences when the data were analyzed by examining those whose PPOI had resolved by day 5(P=0.69)or day 6(P= 0.88).No adverse events related to acupuncture were reported. CONCLUSION:Acupuncture did not prevent PPOI andwas not useful for treating PPOI once it had developed in this population. | M Kay Garcia Joseph S Chiang Bob Thornton J Lynn Palmer Jennifer McQuade Lorenzo Cohen | 2010 | World Journal of Gastroenterology2010，16，1： | 27 |
| 3 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 4 | 高纤维膳食和补充乙酸盐改变肠道菌群,预防醋酸脱氧皮质酮-盐型高血压小鼠高血压和心力衰竭的发展显示文摘水果和蔬菜的膳食摄入与高血压的发生率较低有关,但所涉及的机制尚未阐明。该研究评估了高纤维膳食和短链脂肪酸(short-chain fatty acid,SCFA)(乙酸盐)对肠道微生物群和预防心血管病的影响。方法:用盐皮质激素诱发小鼠高血压模型,观测正常喂食组、高纤维喂食组和补充乙酸盐组的肠道微生物、心脏结构/功能和血压水平。 | 刘莉 叶鹏 Marques FZ Nelson EM Chu PY Horlock D Fiedler A Ziemann M Tan JK Kuruppu S Rajapakse NW El-Osta A Mackay CR Kaye DM | 2016 | 中华高血压杂志2016，24，12： | 8 |
| 5 | 在在母亲胎儿的接口的天生、适应的有免疫力的房间之间的不平衡发生在导致内毒素的 preterm 出生以前显示文摘Preterm 出生(PTB ) 是新生的病态和世界范围的死亡的领先的原因。到在母亲并且在母亲胎儿的接口的一个支持 inflammatory 状态的来自一个反煽动性的状态的转变在微生物引起导致 preterm 劳动的 pathophysiology 被含有。然而,房间哪个免疫者调停,是不清楚的这转变。我们假设了那在在母亲胎儿的接口的天生、适应的有免疫力的房间之间的不平衡将发生在微生物引起导致 preterm 劳动以前。用导致内毒素的 PTB 的一个确定的鼠科的模型,我们的结果证明在交货以前,有 CD4+ 的减小;在子宫的纸巾的规章的 T 房间(Tregs ) 。这减小被子宫的纸巾也不在脾连接到 Tregs 的一个减少的数字,也不到 IL10, CCL17,或 CCL22 的损害生产。到怀孕老鼠的内毒素管理不改变受动器 CD4+在母亲胎儿的接口的 T 房间。然而,它引起在 Tregs 之间的不平衡(CD4+并且 CD8+) ,受动器 CD8+在怒气的 T 房间,和 Th17 房间。另外,到怀孕老鼠的内毒素管理象丰富的 neutrophils 一样由子宫的纸巾导致 CCL2, CCL3, CCL17,和 CCL22 的过多的生产。在子宫的微型环境的这不平衡被象巨噬细胞和 MHC II+ 那样的少见的象 APC 一样房间伴随;neutrophils。一起,这些结果证明到怀孕老鼠的内毒素管理在母亲胎儿的接口引起在天生、适应的有免疫力的房间之间的不平衡。 | Marcia Arenas-Hernandez Roberto Romero Derek St Louis Sonia S Hassan Emily B Kaye Nardhy Gomez-Lopez | 2016 | Cellular & Molecular Immunology2016，13，4： | 6 |
| 6 | Reducing probability of decision error using stochastic resonance 显示文摘 | S kay J Michels H Chen P Varshney | 2006 | IEEE Signal Processing letter2006，13，11： | 1 |
| 7 | Epothilones in the treatment of cancer 显示文摘 | Larkin J M Kaye S B | 2006 | Expert Opin Investig Drugs2006，15，6： | 1 |
| 8 | Brain magnetic resonance imaging with contrast dependent on blc, od oxygenation显示文摘 | Ogawa S Lee T M Kay A R | 1990 | Proceedings of the National Academy of Sciences USA1990，87，98： | 1 |
| 9 | A Fast and accurate single frequency estimator显示文摘 | | 1989 | IEEE Trans Acoustics Speech and Signal Processing1989，37，12： | 1 |
| 10 | Attention deficit in Alzheimer's disease is not stimulated by an anticholinergic/antihistaminergic drug and is distinct from deficits in healthy aging显示文摘 | Oken B Kishiyama S Kaye J | 1994 | Neurology1994，44，2： | 1 |
| 11 | Experience during the learning curve of laser in-situ keratomileusis 显示文摘 | Gimble HV Basti S Kaye GB | 1996 | J Cataract Refract Surg1996，22，： | 1 |
| 12 | Herpes simplex keratitis 显示文摘 | Kaye S Choudhary A | 2006 | Prog Retin Eye Res2006，25，4： | 1 |
| 13 | Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database显示文摘 | Russmann S Kaye JA Jick SS Jick H | 2005 | Br J Clin Pharmacol2005，60，1： | 1 |
| 14 | A bacterial effector acts as a plant transcription factor and induces a cell size regulator显示文摘 | Kay S Hahn S Marois E | 2007 | Science2007，318，5850： | 1 |
| 15 | Effect of root exudates from corn and bromegrass on soil structural stability显示文摘 | POJASAK T KAY S D | 1990 | Canadian Journal of Soil Science1990，70，： | 1 |
| 16 | A Fast and Accurate Single Frequency Estimator显示文摘 | Kay S | | 0，，： | 1 |
| 17 | The sequence of the rice phytochrome gene显示文摘 | Kay S A Keith B Shinozaki K | | 0，，： | 1 |
| 18 | ACR/EULAR 2010 rheumatoid arthritis classification criteria显示文摘 | Kay J Upehurch K S | 2012 | Rheumatology(Oxford)2012，51，6： | 1 |
| 19 | Reductions in C -reactive protein in older adults with type 2 diabetes are related to improvements in body composition follow-ing a randomized controlled trial of resistance training 显示文摘 | Mavros Y Kay S Simpson KA | 2014 | Cachexia Sarcopenia Muscle2014，5，2： | 1 |
| 20 | Carbapenem-resistant Enterobacteriaceae: a review of treatment and outcomes显示文摘 | van Duin D Kaye K S Neuner E A | 2013 | DiangMicrobiollnfectDis2013，75，2： | 1 |
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