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| 1 | Cultured Mycelium Cordyceps sinensis alleviates CCI4-induced liver inflammation and fibrosis in mice by activating hepatic natural killer cells显示文摘目的: 最近的证据证明有教养的菌丝体 Cordyceps sinensis (CMCS ) 有效地在老鼠免于肝纤维变性。这里,我们调查了 CMCS 的 anti-fibrotic 行动是否与它肝的生来的杀手( NK )的活动的规定有关是在 CCl 4-treated mice.Methods 的房间: C57BL/6 老鼠与10% CCl 4被注射( 2 mL/kg , ip ) 3 次每为 4 个星期的星期,并且收到了 CMCS ( 120 mg· ; kg −1·d−1, ig )在这个时期期间。在实验的另一部分,老鼠也与 NK 删除房间的抗体 ASGM-1 被注射(20 μ g, ip ) 在开始的 3 个星期内的 5 次。在老鼠被牺牲以后,浆液肝功能,和肝发炎, hydroxyproline 内容和骨胶原免职被估计。肝的 NK 房间和孤立的肝淋巴细胞上的 NKG2D (NK 房间的激活受体) 的表示的数字用流动 cytometry 被分析。在肝纸巾的 Desmin 表示和房间 apoptosis 分别地用染色的 desmin 和 TUNEL 试金被学习。α 的层次; -SMA, TGF-β, RAE-1δ并且 RAE-1ε在肝,纸巾被 RT-qPCR.Results 决定: 在 CCl 4-treated 鼠标, CMCS 管理显著地改进了肝功能,稀释的肝发炎和纤维变性,并且在肝的 NK 房间上增加了肝的 NK 房间的数字和 NKG2D 的表达式水平。而且, CMCS 管理显著地减少了在肝纸巾的 desmin 表示,和邻近肝的星形的房间的染色的增加的 TUNEL。有 NK 删除房间的 ASGM-1 的注射不仅减少在 CCl 4-treated 老鼠的肝的 NK 房间的数字,而且极大地加速的肝发炎和纤维变性。在有 NK 房间弄空的 CCl 4-treated 老鼠, CMCS 管理速度肝纤维变性开发的率,并且温和地 upregulated 肝的 NK 房间,但是没有改变 NKG2D expression.Conclusion 的数字: CMCS allevi¬经由支持肝的 NK 房间的激活的 ates CCl 4-induced 肝发炎和纤维变性。CMCS 部分颠倒肝的 NK 房间的 ASGM-1-induced 弄空。 | Yuan PENG Kai HUANG Li SHEN Ya n-ya n TAO Cheng-hai LIU | 2016 | Acta Pharmacologica Sinica2016，37，2： | 8 |
| 2 | Source identification, contamination status and health risk assessment of heavy metals from road dusts in Dhaka, Bangladesh显示文摘In this study, concentrations of Cr, Mn, Ni, Cu, Zn, Cd and Pb were determined in road dusts collected from different locations in Dhaka to assess source, contamination status and health risk. Energy-dispersive X-ray fluorescence spectroscopy and energy-dispersive X-ray spectroscopy were used to determine Cr, Mn, Ni, Cu, Zn, Cd and Pb and their mean concentrations were 162.27 ± 29.46, 721.18 ± 180.14, 35.65 ± 12.55, 104.56 ± 128.33, 515.32 ± 321.90,BDL, and 342.82 ± 591.20 mg/kg, respectively. Among the heavy metals, highest concentrations of Cu, Zn and Pb were found at urban sites-7(municipal waste dumping) and 8(medical waste incineration). Highest concentration of Cr followed by Cu and Zn was found at site-5(Tejgaon, urban). Principal component analysis revealed that anthropogenic activities are the potential sources for Cr, Ni, Cu, Zn and Pb while earth crust for Mn. Pollution index and pollution load index results suggested that all the sites were contaminated and/or degraded by Cr, Cu, Zn and Pb except sites-9(urban), 10(sub-urban), 11(rural) while sites-7 and 8(urban) were extremely degraded. For noncarcinogenic health risk, hazard quotient values for dermal were higher compared to that of inhalation/ingestion. Though hazard index values were less than 1 at all the sites, these were at least one order of magnitude higher for children group than that of adult group, thus the children group may face more noncarcinogenic health risk at sites -7 and 8. Values of incremental lifetime cancer risk were from 10to 10showed no carcinogenic health risk by road dusts contaminated with the heavy metals. | Aklima Nargis Ahsan Habib Md Nazrul Islam Kai Chen Md Shafiqul Islam Sarker A N M Al-Razee Wenbin Liu Guorui Liu Minggang Cai | 2022 | Journal of Environmental Sciences2022，34，11： | 3 |
| 3 | An efficient descriptor model for designing materials for solar cells显示文摘An efficient descriptor model for fast screening of potential materials for solar cell applications is presented.It works for both excitonic and non-excitonic solar cells materials,and in addition to the energy gap it includes the absorption spectrum(α(E))of the material.The charge transport properties of the explored materials are modelled using the characteristic diffusion length(Ld)determined for the respective family of compounds.The presented model surpasses the widely used Scharber model developed for bulk heterojunction solar cells.Using published experimental data,we show that the presented model is more accurate in predicting the achievable efficiencies.To model both excitonic and non-excitonic systems,two different sets of parameters are used to account for the different modes of operation.The analysis of the presented descriptor model clearly shows the benefit of includingα(E)and Ld in view of improved screening results. | Fahhad H Alharbi Sergey N Rashkeev Fedwa El-Mellouhi Hans P Lüthi Nouar Tabet Sabre Kais | 2015 | npj Computational Materials2015，，1： | 3 |
| 4 | Fiber gas sensor-integrated smart face mask for roomtemperature distinguishing of target gases显示文摘小、便携式、便宜的便携煤气的传感器在人的健康并且环境监视的即时察觉有大潜在的申请。在这个工作,我们与围单人赛的碳制作了灵活纤维气体传感器 nanotube (SWCNT ) ,多围的碳 nanotube (MWCNT ) ,和 ZnO 量察觉到元素的装饰点的 SWCNT (SWCNTs@ZnO ) 。这些灵活纤维气体传感器能在房间温度被操作与好敏感和恢复时间检测目标气体。他们也展出了优异长期的稳定性,以及好设备机械弯曲能力和坚韧性。把这些灵活煤气的传感器集成到脸面具,制作的便携的聪明的脸面具能被用来有选择地检测 C 2 H 5 哦,由与不同颜色读相应 LEDs 的 HCHO,和 NH 3 。如此的脸面具在新窗户中在事情和便携 electronics.Open | Zhiyi Gao Zhoe n g Lou Shuai Chen La Li Kai Jiang Zuoling Fu Wei Han Guozhen Shen | 2018 | Nano Research2018，11，1： | 3 |
| 5 | CMR Imaging Predicts Death and Other Adverse Events in Suspected Cardiac Sarcoidosis显示文摘 | Simon Greulich Claudia Christina Deluigi Steffen Gloekler Andreas Wahl Christine Zürn Ulrich Kramer Detlev Nothnagel Helmut Bültel Julia Schumm Stefan Grün Peter Ong Anja Wagner Steffen Schneider Kai Nassenstein Meinrad Gawaz Udo Sechtem Oliver Bruder Hei | 2013 | JACC: Cardiovascular Imaging2013，，： | 2 |
| 6 | Traffic at the Edge of Chaos显示文摘 | Steel R | 1994 | Artificial Life1994，，4： | 1 |
| 7 | Large blood pressure variabilityand hypertensive cardiac remodeling-role of cardiac inf lammation显示文摘 | Kai H Kudo H Takayama N | 2009 | Circ J2009，73，12： | 1 |
| 8 | Inhibitory effects of natural plant polyphenolson rat liver glutathione S-transferases显示文摘 | ZHANG Kai DAS N P | 1994 | Biochem Pharmacol1994，47，11： | 1 |
| 9 | A cellular automaton model for freeway traffic显示文摘 | Kai N Michael S | 1992 | J Phys I1992，2，12： | 1 |
| 10 | No-touch isolation technique reduces intraoperative shedding of tumor cells into the portal vein during resection of coloretal cancer 显示文摘 | Hayashi N Egami H Kai M | 1999 | surgery1999，125，4： | 1 |
| 11 | First Scale - Up to Production Scale of a Ring Closing Metathesis Reaction Forming a 15 - Membered Macrocycle as a Precursor of an Active Pharmaceutical Ingredient 显示文摘 | Thomas N Michael B Kai D | 2005 | Org Process Res Dev2005，9，： | 1 |
| 12 | Mutation Analysis of Mycobacterial rpoB Genes and ifampin Resistance Using Ftecombinant Mycobacterium smegmatis显示文摘 | Nakata N Kai M Makino M | 2012 | Antimicrob Agents Chemother2012，56，4： | 1 |
| 13 | Decreased expression of cytokines th at induce type l helper T cell/interfeton-gamma responses in genetically suscep tible mice infected with Mycobacterium avium显示文摘 | Kobayashi K Nakata N Kai M | | 0，，： | 1 |
| 14 | Finite element analysis of the influence of tool edge radius on size effect in orthogonal micro-cutting process显示文摘 | Kai L S N | 2007 | International Journal of Mechanical Sciences2007，49，： | 1 |
| 15 | A cellular automaton model for freeway traffic显示文摘 | Kai N Michael S | 1992 | J Phys I1992，2，12： | 1 |
| 16 | The effects of heat treatment on the carbide evo-lution and the chromium depletion along grain boundary of Inconel690 alloy显示文摘 | Kai J J Liu M N | | 0，，01： | 1 |
| 17 | Melkote Finite element analysis of the influence of tool edge radius on size effect in orthogonal micro-cutting process显示文摘 | Kai Liu Shreyes N | 2007 | International Journal of Mechanical Sciences2007，49，： | 1 |
| 18 | Large blood pressure variability and hypertensive cardiac remodeling-role of cardiac inflammation显示文摘 | Kai H Kudo H Takayama N | 2009 | Circ J2009，73，： | 1 |
| 19 | No touch isolation technique reduces intraoperative shedding of tumor cells in- to the portal vein duing resection of colorectal cancer 显示文摘 | Hayashi N Egami H Kai M | 1999 | Surgery1999，125，4： | 1 |
| 20 | TCP in wireless environments:problems and solutions显示文摘 | Kai Xu Ansari N | 2005 | Communications Magazine IEEE2005，43，3： | 1 |
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