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| 1 | Gastrointestinal dysfunction in liver cirrhosis显示文摘Patients with liver cirrhosis exhibit several features of gut dysfunction which may contribute to the development of cirrhosis complications as well as have an impact on nutritional status and health-related quality of life.Gastrointestinal symptoms are common in cirrhosis and their pathophysiology probably involves factors related to liver disease severity,psychological distress,and gut dysfunction(e.g.,increased gastric sensitivity to distension and delayed gut transit).They may lead to reduced food intake and,thus,may contribute to the nutritional status deterioration in cirrhotic patients.Although tense ascites appears to have a negative impact on meal-induced accommodation of the stomach,published data on gastric accommodation in cirrhotics without significant ascites are not unanimous.Gastric emptying and small bowel transit have generally been shown to be prolonged.This may be related to disturbances in postprandial glucose,insulin,and ghrelin levels,which,in turn,appear to be associated to insulin resistance,a common finding in cirrhosis.Furthermore,small bowel manometry disturbances and delayed gut transit may be associated with the development of small bowel bacterial overgrowth.Finally,several studies have reported intestinal barrier dysfunction in patients with cirrhosis(especially those with portal hypertension),which is related to bacterial translocation and permeation of intestinal bacterial products,e.g.,endo-toxin and bacterial DNA,thus potentially being involved in the pathogenesis of complications of liver cirrhosis. | Evangelos Kalaitzakis | 2014 | World Journal of Gastroenterology2014，20，40： | 24 |
| 2 | EUS-guided drainage is more successful in pancreatic pseudocysts compared with abscesses显示文摘AIM: To compare the results for endoscopic ultrasound (EUS)-guided drainage of clear fluid pancreatic pseudocysts with the results for abscess drainage. METHODS: All patients referred for endoscopic drainage of a fluid collection were prospectively included. The outcome was recorded. RESULTS: Altogether 26 pseudocysts or abscesses were treated in 25 (6 female) patients. One endoscopist performed the procedures. Non-infected pseudocysts were present in 15 patients and 10 patients had infected fluid collections. The cyst size ranged between 28 cm × 13 cm and 5 cm × 5 cm. The EUS drainage was successful in 94% of the pseudocysts and in 80% of the abscesses (P = 0.04). The complication rate in pseudocysts was 6% and in abscesses was 30% (P = 0.02). Recurrence of a pseudocyst occurred in one patient (4%) after 6 mo; the patient was successfully retreated. CONCLUSION: EUS-guided drainage of pseudocysts is associated with a higher success rate and a lower complication rate compared with abscess drainage. | Riadh Sadik Evangelos Kalaitzakis Anders Thune Jan Hansen Claes Jnson | 2011 | World Journal of Gastroenterology2011，17，4： | 12 |
| 3 | Hepatic encephalopathy in patients with liver cirrhosis:Is there a role of malnutrition?显示文摘Hepatic encephalopathy(HE) is a common complica-tion in patients with liver cirrhosis but its pathogenesis remains incompletely understood.Malnutrition is com-monly encountered in patients with liver cirrhosis and it has been reported to affect the quality of life of this group of patients.Experimental studies suggest that low energy intake and poor nutritional status may facil-itate the development of HE but there are scarce data on the potential role of malnutrition in HE in patients with liver cirrhosis.Two recently published studies have evaluated the potential role of malnutrition in the development of HE in cirrhotic patients with conflicting results.In this letter to the editor we briefly present the results of the two studies as well as potential rea-sons for the conflicting results reported. | Evangelos Kalaitzakis Einar Bjrnsson | 2008 | World Journal of Gastroenterology2008，14，21： | 7 |
| 4 | Intraductal papillary mucinous neoplasm in chronic calcifying pancreatitis:Egg or hen?显示文摘Intraductal papillary mucinous neoplasm(IPMN)is an increasingly reported entity.Extensive pancreatic calcification is generally thought to be a sign of chronic pancreatitis,but it may occur simultaneously with IPMN leading to diagnostic difficulties.We report a case of a patient initially diagnosed with chronic calcifying pancreatitis who was later shown to have a malignant IPMN.This case illustrates potential pitfalls in the diagnosis of IPMN in the case of extensive pancreatic calcification as well as clues that may lead the clinician to suspecting the diagnosis.The possible mechanisms of the relation between pancreatic calcification and IPMN are also reviewed. | Evangelos Kalaitzakis Barbara Braden Palak Trivedi Yalda Sharifi Roger Chapman | 2009 | World Journal of Gastroenterology2009，15，10： | 3 |
| 5 | Addition of senna improves quality of colonoscopy preparation with magnesium citrate显示文摘AIM: To prospectively investigate the effectiveness and patient’s tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. METHODS: A total of 342 patients who were referred for colonoscopy underwent a colon cleansing protocol with magnesium citrate alone (n = 160) or magnesium citrate and senna granules (n = 182). The colonoscopist rated the overall efficacy of colon cleansing using an established score on a 4-point scale. Patients were questioned before undergoing colonoscopy for side effects and symptoms during bowel preparation. RESULTS: The percentage of procedures rescheduled because ofinsufficient colon cleansing was 7% in the magnesium citrate group and 4% in the magnesium citrate/senna group (P = 0.44). Adequate visualization of the colonic mucosa was rated superior under the citramag/senna regimen (P = 0.004). Both regimens were well tolerated, and did not significantly differ in the occurrence of nausea, bloating or headache.However, abdominal cramps were observed more often under the senna protocol (29.2%) compared to the magnesium citrate only protocol (9.9%, P < 0.0003). CONCLUSION: The addition of senna to the bowel preparation protocol with magnesium citrate significantly improves the cleansing outcome. | Stergios Vradelis Evangelos Kalaitzakis Yalda Sharifi Otto Buchel Satish Keshav Roger W Chapman Barbara Braden | 2009 | World Journal of Gastroenterology2009，15，14： | 3 |
| 6 | Gastrointestinal symptoms in patients with cirrhosis: a longitudinal study before and after liver transplantation显示文摘 | Evangelos Kalaitzakis Axel Josefsson Maria Castedal Pia Henfridsson Maria Bengtsson Bengt Andersson Einar Bjö rnsson | 2013 | Scandinavian Journal of Gastroenterology2013，，11： | 2 |
| 7 | Healthcare‐associated and nosocomial bacterial infections in cirrhosis: predictors and impact on outcome显示文摘 | Konstantina Sargenti Hanne Prytz Anna Strand Emma Nilsson Evangelos Kalaitzakis | 2015 | Liver Int2015，，2： | 2 |
| 8 | Portal vein cannulation:An uncommon complication of endoscopic retrograde cholangiopancreatography显示文摘Portal vein cannulation is a rare complication of endo-scopic retrograde cholangiopancreatography(ERCP).It has been reported that it usually occurs after endo-scopic sphincterotomy,whereas in cases without prior sphincterotomy,the presence of portobiliary fistulas has been shown.Here,we present a case in which cannulation of the portal vein occurred despite careful wire-guided cannulation and the absence of sphinc-terotomy.Although fatal cases of cerebral and pulmo-nary air and/or bile embolism have been reported in patients with combined portal and hepatic vein trauma after ERCP and sphincterotomy,isolated portal vein cannulation,as in the current case,does not usu-ally result in mortality or serious morbidity.However,awareness of this rare complication is important so that no further intervention is performed. | Evangelos Kalaitzakis Nicholas Stern Richard Sturgess | 2011 | World Journal of Gastroenterology2011，17，46： | 2 |
| 9 | Hepatotoxicity associated with statins:Reports of idiosyncratic liver injury post-marketing显示文摘 | Bj?rnsson E Jacobsen EI Kalaitzakis E | | 0，，： | 1 |
| 10 | A review of esomeprazole in the treatment of gastroesophageal reflux disease 显示文摘 | KALAITZAKIS E BJORNSSON E | 2007 | Ther Clin Risk Manag2007，3，4： | 1 |
| 11 | Development of a microcontroller based, pbotovoltaic maximum power point tracking control system 显示文摘 | KOUTROULIS E KALAITZAKIS K VOULGARIS N C | 2001 | IEEE Transaction on Power Electronics2001，16，1： | 1 |
| 12 | Adjuvant chemotherapy should be used as the standard of care for resectable pancreatic cancer显示文摘 | Amptoulach S Kalaitzakis E Azam F | 2009 | Can Ther2009，7，1： | 1 |
| 13 | Design of a maximum power tracking system for wind-energy-conversion applications 显示文摘 | EFTICHIOS KOUTROULIS KOSTAS Kalaitzakis | 2006 | IEEE Transactions on Industrial Electronics2006，53，2： | 1 |
| 14 | Hepatic en- cephalopathy is related to anemia and fat - free mass depletion in liver transplant candidates with cirrhosis显示文摘 | Kalaitzakis E Josefsson A Castedal M | 2013 | Scand J Gas- troenterol2013，，： | 1 |
| 15 | Design of a maxi- mum power tracking system for wind energy conversion applications 显示文摘 | KOUTROULIS E KALAITZAKIS K | 2006 | IEEE Transactions on Industrial Elec- tronics2006，53，2： | 1 |
| 16 | Methodology for optimal sizing of stand-alone photovoltaic/wind-generator systems using genetic algorithms显示文摘 | Eftichios Koutroulis Dionissia Kolokotsa Antonis Potirakis Kostas Kalaitzakis | 2005 | Solar Energy2005，，9： | 1 |
| 17 | A survey of video processing techniques for traffic applications显示文摘 | Kastrinak V Zervakis M kalaitzakis K | 2003 | Image and Vision Computing2003，21，4： | 1 |
| 18 | Developmentof a microcontroller-based, photovoltaic maximum power point tracking control system显示文摘 | Koutroulis E Kalaitzakis K Voulgaris N C | 2001 | IEEE Transactions on Power Electronics2001，16，1： | 1 |
| 19 | Clinicopathologic evaluation of hepatic lipidosis in periparturient dairy cattle显示文摘 | Kalaitzakis E Roubies N Panousis N | 2007 | Journal of Veterinary Internal Medicine2007，21，4： | 1 |
| 20 | Long-term follow-up of patients with mild to moderate drug-induced liver injury显示文摘 | Bjornsson E Kalaitzakis E Av Klinteberg Y | 2007 | Alimentary Pharmacology & Therapeutics2007，26，1： | 1 |
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