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1Biodegradation of polycyclic aromatic hydrocarbons(PAHs)by fungal enzymes:A review显示文摘Polycyclic aromatic hydrocarbons(PAHs) are a large group of chemicals.They represent an important concern due to their widespread distribution in the environment,their resistance to biodegradation,their potential to bioaccumulate and their harmful effects.Several pilot treatments have been implemented to prevent economic consequences and deterioration of soil and water quality.As a promising option,fungal enzymes are regarded as a powerful choice for degradation of PAHs.Phanerochaete chrysosporium,Pleurotus ostreatus and Bjerkandera adusta are most commonly used for the degradation of such compounds due to their production of ligninolytic enzymes such as lignin peroxidase,manganese peroxidase and laccase.The rate of biodegradation depends on many culture conditions,such as temperature,oxygen,accessibility of nutrients and agitated or shallow culture.Moreover,the addition of biosurfactants can strongly modify the enzyme activity.The removal of PAHs is dependent on the ionization potential.The study of the kinetics is not completely comprehended,and it becomes more challenging when fungi are applied for bioremediation.Degradation studies in soil are much more complicated than liquid cultures because of the heterogeneity of soil,thus,many factors should be considered when studying soil bioremediation,such as desorption and bioavailability of PAHs.Different degradation pathways can be suggested.The peroxidases are heme-containing enzymes having common catalytic cycles.One molecule of hydrogen peroxide oxidizes the resting enzyme withdrawing two electrons.Subsequently,the peroxidase is reduced back in two steps of one electron oxidation.Laccases are copper-containing oxidases.They reduce molecular oxygen to water and oxidize phenolic compounds.Tayssir Kadri Tarek Rouissi Satinder Kaur Brar Maximiliano Cledon Saurabhjyoti Sarma Mausam Verma 2017Journal of Environmental Sciences2017,29,1:19
2Circulating microRNAs in patients with non-alcoholic fatty liver disease显示文摘AIM: To identify novel non-invasive biomarkers for non-alcoholic fatty liver disease(NAFLD). METHODS: Twenty patients with histologically proven NAFLD and 20 controls were included. All NAFLD cases were scored using the NAFLD activity score. The rela-tive expressions of miR-197, miR-146 b, miR-10 b, miR-181d, miR-34 a, miR-122, miR-99 a and miR-29 a were analyzed using real-time polymerase chain reaction. RESULTS: Serum levels of miR-181 d, miR-99 a, miR-197 and miR-146 b were significantly lower in biopsy-proven NAFLD patients than in the healthy controls. Serum lev-els of miR-197 and miR-10 b were inversely correlated with degree of inflammation and miR-181 d and miR-99 a were inversely correlated with serum gamma glu-tamyl transferase levels in non-alcoholic steatohepatitis patients. CONCLUSION: NAFLD is associated with altered se-rum miRNA expression pattern. This study provides clues for defining the non-invasive diagnosis of NAFLD.Serkan Dogan Gokmen Zararsiz Sebnem Gursoy Kadri Guven Omer Ozbakir Munis Dundar Mehmet Yucesoy 2014World Journal of Hepatology2014,6,8:13
3Noninvasive assessment of liver damage in chronic hepatitis B显示文摘AIM:To evaluate the efficacy of the aspartate aminotransferase/platelet ratio index(APRI)and neutrophillymphocyte(N/L)ratio to predict liver damage in chronic hepatitis B(CHB).METHODS:We analyzed 89 patients diagnosed with CHB by percutaneous liver biopsy and 43 healthy subjects.Liver biopsy materials were stained with hematoxylin-eosin and Masson’s trichrome.Patients’fibrosis scores and histological activity index(HAI)were calculated according to the Ishak scoring system.Fibrosis score was recognized as follows:F0-1 No/early-stage fibrosis,F2-6 significant fibrosis,F0-4 non-cirrhotic and F5-6 cirrhotic.Significant liver fibrosis was defined as an Ishak score of≥2.APRI and N/L ratio calculation was made by blood test results.RESULTS:The hepatitis B and control group showed no difference in N/L ratios while there was a significant difference in terms of APRI scores(P<0.001).Multiple logistic regression analysis revealed that the only independent predictive factor for liver fibrosis in CHB was platelet count.APRI score was significantly higher in cirrhotic patients than in non-cirrhotic patients.However,this significance was not confirmed by multiple logistic regression analysis.The optimum APRI score cut-off point to identify patients with cirrhosis was 1.01with sensitivity,specificity,positive predictive value and negative predictive value of 62%(36%-86%),74%(62%-83%),29%(13%-49%)and 92%(82%-97%),respectively.In addition,correlation analyses revealed that N/L ratio has a negative and significant relationship with HAI(r=-0.218,P=0.041).CONCLUSION:N/L ratio was negatively correlated with HAI.APRI score may be useful to exclude cirrhosis in CHB patients.Mehmet Celikbilek Serkan Dogan Sebnem Gursoy Gokmen Zararsιz Alper Yurci Omer Ozbakιr Kadri Guven Mehmet Yucesoy 2013World Journal of Hepatology2013,5,8:5
4Leucocyte-and platelet-rich fibrin as a rescue therapy for small-to-medium-sized complex wounds of the lower extremities显示文摘Background:Generally,advanced wound care resources are applied for complex wounds that pose a challenge to the medical and nursing teams.In this report,the use of leukocyte-and platelet-rich fibrin(L-PRF)is emphasized for complex wounds as an alternative,simple,inexpensive,time-saving process that does not require hospitalization and has a healing potential over that of bare soft tissue,including bone,tendon,and ligaments.The aim of this study is to extend the use of L-PRF in small-to-moderate-sized complex wounds of lower extremities in which L-PRF maintains the sensitive structures viable.Methods:Between January 2016 and December 2017,17 small-to-moderate-sized complex wounds of lower extremities treated with L-PRF were recruited from the plastic and reconstructive surgery clinic in Aydin State Hospital,Turkey.The treatment was administered twice per week in the outpatient clinic.Depending on the size and extension of the complex wound,two to five blood samples were collected into 8.5 ml dry,glass vacuum tubes with no anticoagulant,and samples were immediately centrifuged at 1630×g for 5 min to obtain L-PRF.Complete healing was defined as the day of complete wound epithelialization.Results:The median values of the initial wound size and wound duration were 12 cm^(2)(interquartile range,6 to 23 cm^(2))and 8 months before first admission(interquartile range,4 to 18 months),respectively.All wounds showed significant improvements after L-PRF therapy and full closure after a median of 18months,with an interquartile range of 11 to 34 months of L-PRF applications.There were recurrences of wounds during the first 6 months after therapy.No adverse events were observed.Conclusions:Our results add to the growing evidence that L-PRF treatments protect and maintain bare soft tissue structures viable,facilitate the formation of granulation tissue and epithelization,and remarkably reduce the need for additional soft tissue surgeries in small-to-medium-sized complex wounds.Kadri Ozer Ozlem Colak 2019Burns & Trauma2019,7,1:4
5Epinephrine plus argon plasma or heater probe coagulation in ulcer bleeding显示文摘AIM:To compare the effectiveness of argon plasma coagulation (APC) and heater probe coagulation (HPC) in non-variceal upper gastrointestinal bleeding.METHODS:Eighty-five (18 female,67 male) patients admitted for acute gastrointestinal bleeding due to gastric or duodenal ulcer were included in the study.Upper endoscopy was performed and HPC or APC were chosen randomly to stop the bleeding.Initial hemostasis and rebleeding rates were primary and secondary end-points of the study.RESULTS:Initial hemostasis was achieved in 97.7% (42/43) and 81% (36/42) of the APC and HPC groups,respectively (P < 0.05).Rebleeding rates were 2.4% (1/42) and 8.3% (3/36) in the APC and HPC groups,respectively,at 4 wk (P > 0.05).CONCLUSION:APC is an effective hemostatic method in bleeding peptic ulcers.Larger multicenter trials are necessary to confirm these results.Ahmet Karaman Mevlut Baskol Sebnem Gursoy Edip Torun Alper Yurci Banu Demet Ozel Kadri Guven Omer Ozbakir Mehmet Yucesoy 2011World Journal of Gastroenterology2011,17,36:4
6毛木耳子实体蛛网病的病害特征及致病菌Cladobotryum cubitense的生理特性和防控策略显示文摘从2010年起,在江苏省丰县毛木耳Auriculariacornea产区观察到蛛网病症状,该病害的发生呈逐年上升趋势,对毛木耳产量和产业造成了严重的损失。经过2015–2016年两年的调查研究,分析毛木耳蛛网病的发病规律。致病菌分别与毛木耳菌丝体和子实体的互作研究表明,该病原真菌仅危害毛木耳子实体,使毛木耳子实体的子实层出现裂缝,进而引起子实体畸形甚至停止生长。该病原本被鉴定为Cladobotryum cubitense。经37℃高温处理7d可抑制其菌丝的生长,50%咪鲜胺锰盐也能够抑制C. cubitense菌丝的生长,为减轻或控制毛木耳蛛网病的发生和传播提供了可行性策略。王刚正 罗义 李佳璐 P?LDMAA Kadri 边银丙 周雁 2019菌物学报2019,38,3:4
7General characteristics of patients with electrolyte imbalance admitted to emergency department显示文摘BACKGROUND:Fluid and electrolyte balance is a key concept to understand for maintaining homeostasis,and for a successful treatment of many metabolic disorders.There are various regulating mechanisms for the equilibrium of electrolytes in organisms.Disorders of these mechanisms result in electrolyte imbalances that may be life-threatening clinical conditions.In this study we defined the electrolyte imbalance characteristics of patients admitted to our emergency department.METHODS:This study was conducted in the Emergency Department(ED) of Uludag University Faculty of Medicine,and included 996 patients over 18 years of age.All patients had electrolyte imbalance,with various etiologies other than traumatic origin.Demographic and clinical parameters were collected after obtaining informed consent from the patients.The ethical committee of the university approved this study.RESULTS:The mean age of the patients was 59.28±16.79,and 55%of the patients were male.The common symptoms of the patients were dyspnea(14.7%),fever(13.7%),and systemic deterioration(11.9%);but the most and least frequent electrolyte imbalances were hyponatremia and hypermagnesemia,respectively.Most frequent findings in physical examination were confusion(14%),edema(10%) and rales(9%);and most frequent pathological findings in ECG were tachycardia in24%,and atrial fibrillation in 7%of the patients.Most frequent comorbidity was malignancy(39%).Most frequent diagnoses in the patients were sepsis(11%),pneumonia(9%),and acute renal failure(7%).CONCLUSIONS:Electrolyte imbalances are of particular importance in the treatment of ED patients.Therefore,ED physicians must be acknowledged of their fluid-electrolyte balance dynamics and general characteristics.Arif Kadri Balci Ozlem Koksal Ataman Kose Erol Armagan Fatma Ozdemir Taylan Inal Nuran Oner 2013World Journal of Emergency Medicine2013,4,2:3
8Characteristics of sildenafil erections in healthy young men显示文摘瞄准:在夜的阴茎勃起以后决定 sildenafil 柠檬酸盐的效果(即发作,勃起的持续时间,和在第一和第二勃起之间的间隔的时间) 健康年轻男人。方法:22 个有势力男人, 23-29 岁,为学习被招募。所有题目用监视设备的 RigiScan 在连续夜里完成了三个会议(Dacomed,明尼阿波利斯,美国) 。在改编的第一夜里以后,夜里 2 记录是他们的基线价值,并且在夜里 3 上,他们收到了 sildenafil 柠檬酸盐的 100 mg。统计比较在第二和第三个夜里数据之间被做。结果:有 sildenafil 柠檬酸盐的第一勃起的发作的吝啬的时间是(34+/-18 ) min,而它是(74+/-24 ) 没有 sildenafil 的 min (P 0.0001 ) 柠檬酸盐。在 sildenafil 柠檬酸盐药以后在开始的 5 h 期间观察的勃起的数字是与没有药(P=0.001 ) 的 2.4+/-0.5 相对照的 3.6+/-0.5。在第一和第二勃起之间的间隔与 sildenafil 柠檬酸盐是更短的:(52+/-26 ) min 对(85+/-34 ) min (P = 0.01 ) 。最后勃起的持续时间是统计上与 sildenafil 柠檬酸盐显著地更长:(64 +/-33 ) min 对(42 +/-28 ) min (P 0.001 ) 。结论:健康年轻男人比 1 h 间隔由制造商求婚在 sildenafil 柠檬酸盐管理以后在 34 min 以内完成了勃起,它短。在第一和第二勃起之间的间隔更短,最后夜的勃起的持续时间更长。Onder Yaman Zafer Tokatli Murat Akand Atilla H. Elhan Kadri Anafarta 2005Asian Journal of Andrology2005,7,4:2
9Viscous falling film instability around a vertical moving cylinder显示文摘The present work discusses both the linear and nonlinear stability conditions of a viscous falling film down the outer surface of a solid vertical cylinder which moves in the direction of its axis with a constant velocity.After studying the linear conditions,a generalized nonlinear kinematic model is then derived to present the physical system.Applying the boundary conditions,analytical solutions are obtained using the long-wave perturbation method.In the first step,the normal mode method is used to characterize the linear behaviors.In the second step,the nonlinear film flow model is solved by using the method of multiple scales,to obtain Ginzburg-Landau equation.The influence of some physical parameters is discussed in both linear and nonlinear steps of the problem,and the results are displayed in many plots showing the stability criteria in various parameter planes.Kadry Zakaria Yasser Gamiel 2012Acta Mechanica Sinica2012,28,2:2
10Intelligent Deep Learning Enabled Human Activity Recognition for Improved Medical Services显示文摘Human Activity Recognition(HAR)has been made simple in recent years,thanks to recent advancements made in Artificial Intelligence(AI)techni-ques.These techniques are applied in several areas like security,surveillance,healthcare,human-robot interaction,and entertainment.Since wearable sensor-based HAR system includes in-built sensors,human activities can be categorized based on sensor values.Further,it can also be employed in other applications such as gait diagnosis,observation of children/adult’s cognitive nature,stroke-patient hospital direction,Epilepsy and Parkinson’s disease examination,etc.Recently-developed Artificial Intelligence(AI)techniques,especially Deep Learning(DL)models can be deployed to accomplish effective outcomes on HAR process.With this motivation,the current research paper focuses on designing Intelligent Hyperparameter Tuned Deep Learning-based HAR(IHPTDL-HAR)technique in healthcare environment.The proposed IHPTDL-HAR technique aims at recogniz-ing the human actions in healthcare environment and helps the patients in mana-ging their healthcare service.In addition,the presented model makes use of Hierarchical Clustering(HC)-based outlier detection technique to remove the out-liers.IHPTDL-HAR technique incorporates DL-based Deep Belief Network(DBN)model to recognize the activities of users.Moreover,Harris Hawks Opti-mization(HHO)algorithm is used for hyperparameter tuning of DBN model.Finally,a comprehensive experimental analysis was conducted upon benchmark dataset and the results were examined under different aspects.The experimental results demonstrate that the proposed IHPTDL-HAR technique is a superior per-former compared to other recent techniques under different measures.E.Dhiravidachelvi M.Suresh Kumar L.D.Vijay Anand D.Pritima Seifedine Kadry Byeong-Gwon Kang Yunyoung Nam 2023Computer Systems Science & Engineering2023,44,2:2
11The anatomical basis for surgical preservation of temporal muscle显示文摘 Al-Mefty O 2004J Neurosurg2004,100,:1
12An Improved Maxi-mum Power Point Tracking for Photovoltaic Grid-con-nected Inverter Based on Voltage-oriented Control显示文摘Kadri R Gaubert J P Champenois G 2011In-dustrial Electronics IEEE Trans on2011,58,1:1
13Modeling reactive blending: An experimental approach显示文摘Hu Guohua Kadri I 1998Journal of Polymer Science( part B) : Polymer Physics1998,36,12:1
14Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis 显示文摘Kadri A Ea HK Bazille C 2008Arthritis Rheum2008,58,8:1
15Endothelial Dysfunction and Increased Responses to Renal Nerve Stimulation in Rat Kidneys during Rhabdomyolysis-Induced Acute Renal Failure: Role of Hydroxyl Radical显示文摘Onur Cil Mert Ertunc Kadri Safak Gucer Fatih Ozaltin Alper Bektas Iskit Rustu Onur 2012Renal Failure2012,,2:1
16Impact of slime disper- sants and anti-adhesives on in vitro biofilm formation of Staphylococcus epidermidis on intraocular lenses and on antibiotic activities显示文摘KADRY A A FOUDA S I SHIBL A M 2009J An- timicrob Chemother2009,63,3:1
17Immunosuppression in liver transplantation= beyond calcineurin inhibitors 显示文摘Fung J Kelly D Kadry Z 2005Liver Transpl2005,11,:1
18An improved maximum power point tracking for photovoltaic grid- connected inverter based on voltage-oriented control 显示文摘Kadri R Gaubert J P Champenois G 2011IEEE Transactions on Industrial Electronics2011,58,1:1
19Students' andteachers'perceptions of clinical assessment program:A qualitative study in a PBL curriculum显示文摘A l Kadri HM Al-Moamary M S van der Vleuten C 0,,02:1
20Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction显示文摘Roula A Farah Khalil S Jalkh Hussein Z Farhat Paul E Sayad Adel M Kadri 2011Blood Coagulation & Fibrinolysis2011,,2:1
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