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| 1 | Status of colitis-associated cancer in ulcerative colitis显示文摘Surgical therapy for ulcerative colitis(UC) depends on the medical therapy administered for the patient's condition. UC is a benign disease. However, it has been reported that the rare cases of cancer in UC patients are increasing, and such cases have a worse prognosis. Recently, surgical therapy has greatly changed, there has been quite an increase in the number of UC patients with high-grade dysplasia and/or cancer. These lesions are known as colitis-associated cancer(CAC). The relationship between inflammation and tumorigenesis is well-established, and in the last decade, a great deal of supporting evidence has been obtained from genetic, pharmacological, and epidemiological studies. Inflammatory bowel disease, especially UC, is an important risk factor for the development of colon cancer. We should determine the risk factors for UC patients with cancer based on a large body of data, and we should attempt to prevent the increase in the number of such patients using these newly identified risk factors in the near future. Actively introducing the surgical treatment in addition to medical treatment should be considered. Several physicians should analyze UC from their unique perspectives in order to establish new clinically relevant diagnostic and treatment methods in the future. This article discusses CAC, including its etiology, mechanism, diagnosis, and treatment in UC patients. | Tetsushi Kinugasa Yoshito Akagi | 2016 | World Journal of Gastrointestinal Oncology2016，8，4： | 11 |
| 2 | 直肠全系膜切除术中在Denonvilliers筋膜后进行手术操作以保护泌尿生殖系统的自主神经:应用尸体标本的组织学研究,包括利用新鲜尸体模型的外科实验 | Kinugasa Y. Murakami G. Uchimoto K. 程妍 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，0，12： | 10 |
| 3 | Detection of K‐ras gene mutation by liquid biopsy in patients with pancreatic cancer显示文摘 | Hideaki Kinugasa Kazuhiro Nouso Koji Miyahara Yuki Morimoto Chihiro Dohi Koichiro Tsutsumi Hironari Kato Takehiro Matsubara Hiroyuki Okada Kazuhide Yamamoto | 2015 | Cancer2015，，13： | 4 |
| 4 | Risk factors for recurrence after transarterial chemoembolization for early-stage hepatocellular carcinoma显示文摘 | Hideaki Kinugasa Kazuhiro Nouso Yasuto Takeuchi Tetsuya Yasunaka Hideki Onishi Shin-ichiro Nakamura Hidenori Shiraha Kenji Kuwaki Hiroaki Hagihara Fusao Ikeda Yasuhiro Miyake Akinobu Takaki Kazuhide Yamamoto | 2012 | Journal of Gastroenterology2012，，4： | 2 |
| 5 | Clinical outcomes of extended esophagectomy with three -field lymph node dissection for e- sophageal squamous cell carcinoma 显示文摘 | Tachibana M Kinugasa S Yoshlmura H | 2005 | Am J Surg2005，，： | 1 |
| 6 | Operating behind Denonvilliers' fascia for reliable preservation of urogenital autonomic nerves in total mesorectal excision:a histologic study using cadaveric specimens,including a surgical experiment using fresh cadaveric models显示文摘 | Kinugasa Y Murakami G Uchimoto K | | 0，，07： | 1 |
| 7 | Expression of membrane cofactor protein ( MCP, CD46) in human liver diseases显示文摘 | Kinugasa N Higashi T Nouso K | 1999 | Br J Cancer1999，80，： | 1 |
| 8 | Quantitative com-parison of a corona-charged aerosol detector and an evapo-rative light-scattering detector for the analysis of a syntheticpolymer by supercritical fluid chromatography显示文摘 | Takahashi K Kinugasa S Senda M | 2008 | J Chro-matogr A2008，1193，12： | 1 |
| 9 | IL-2 receptor β subunit dependent and independent regulation of intestinal epithelial tight junctions显示文摘 | Nishiyama R Sakaguchi T Kinugasa T | 2001 | Biol Chem2001，21，35： | 1 |
| 10 | Esophageal cancer patients surviving 6 years after esophagectomy 显示文摘 | Tachibana M Dhar DK Kinugasa S | 2002 | Langenbecks Arch Surg2002，387，8： | 1 |
| 11 | Thigh muscle activation distribution and pulmonary V02 kinetics during moderate, heavy, and very heavy intensity cycling exercise in humans 显示文摘 | Endo MY Kobayakawa M Kinugasa R | 2007 | Am J Physiol Regul Integr Comp Physiol2007，293，： | 1 |
| 12 | Postoperative chemotherapy vs chemoradiotherapy for thoracic esophageal cancer: a prospective randomized clinical trial显示文摘 | Taehibana M Yoshimura H Kinugasa S | 2003 | Eur J Surg Oncol2003，29，7： | 1 |
| 13 | East asian economic develop-ment :two demographic dividends显示文摘 | MASON A KINUGASA T | 2008 | Journal of Asian E-conomics2008，，19： | 1 |
| 14 | Surgical treatment of moyamoya disease:operative technique for encephlo-duro-arterio-myosynangiosis,its follow-up,clinical results and angiograms显示文摘 | Kinugasa K Mandai S Kamata I | 1993 | Neurosurgery1993，32，4： | 1 |
| 15 | Claudin-1 protein is a major factor involved in the tumorigenesis of colorectal cancer显示文摘 | Huo Q Kinugasa T Wang L | 2009 | Anticancer Res2009，29，3： | 1 |
| 16 | Uremic encephalopathy,dialysis encephalopathy显示文摘 | Kinugasa E | 2004 | Nippon Rinsho2004，，： | 1 |
| 17 | Oncologic outcomes of intersphincteric resection without preoperative chemoradiotherapy for very low rectal cancer显示文摘 | Yoshito Akagi Kazuo Shirouzu Yutaka Ogata Tetsushi Kinugasa | 2013 | Surgical Oncology2013，，2： | 1 |
| 18 | Clinical outcomes of extended esophagectomy with three--field lymph node dissection for esophageal squamous cell carcinoma 显示文摘 | Tachibana M Kinugasa S Yoshimura H | 2005 | Am J Surg2005，189，1： | 1 |
| 19 | Lymph node evaluation and survival in colorectal cancer: Review of population-based, prospective studies显示文摘 | AKAGI Y ADACHI Y KINUGASA T | 2013 | Anticancer Res2013，33，7： | 1 |
| 20 | Clinical out- comes of extended esophagectomy with three-field lymph node dissection for esophageal squamous cell carcinoma 显示文摘 | Tachibana M Kinugasa S Yoshimura H | 2005 | Am J Surg2005，189，1： | 1 |
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