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| 1 | Treatment of over 20 mm gastric cancer by endoscopic submucosal dissection using an insulation-tipped diathermic knife显示文摘AIM: To evaluate the effectiveness of endoscopic submucosal dissection using an insulation-tipped diathermic knife (IT-ESD) for the treatment of patients with over 20 mm early gastric cancer (EGC). METHODS: A total of 112 patients with over 10 mm EGC were treated with IT-ESD at Sumitomo Besshi Hospital and Shikoku Cancer Center in the 5 year period from January 2002 to December 2006, including 40 patients with over 20 mm EGC. We compared patient backgrounds, the one-piece resection rate, complete resection (CR) rate, operation time, bleeding rate, perforation rate between patients with over 20 mm EGC [over 20 mm group (21-40 mm)] and the remaining patients (under 20 mm group). RESULTS: We found no significant difference in the rate of underlying cardiopulmonary disease (over 20 mm group vs under 20 mm group, 5.0% vs 5.6%), one- piece resection rate (95% vs 96%), CR rate (85% vs 89%), operation time (72.3 min vs 66.5 min), bleeding rate (5% vs 4.2%), and perforation rate (0% vs 1.4%) between the 2 groups. Three patients in each group had submucosal invasion and two in each groups underwent additional surgery. CONCLUSION: There was no significant difference in the outcome resulting from IT-ESD between the 2 groups. Our study proves that IT-ESD is a feasible treatment for patients with over 20 mm mucosal gastric cancer although the long-term outcome should be evaluated in the future. | Shoji Hirasaki Hiromitsu Kanzaki Minoru Matsubara Kohei Fujita Fusao Ikeda Hideaki Taniguchi Eiichiro Yumoto Seiyuu Suzuki | 2007 | World Journal of Gastroenterology2007，13，29： | 13 |
| 2 | Three cases of Solitary Peutz-Jeghers-type hamartomatous polyp in the duodenum显示文摘A solitary Peutz-Jeghers-type hamartomatous polyp in the duodenum is rare, and few reports have described its characteristic endoscopic features. We describe three cases of solitary Peutz-Jeghers-type hamartomatous polyp and their endoscopic findings in detail. The polyp in all of our three cases showed an irregularly lobular or nodular surface, whereas adenomas often show a regularly nodular or granular surface. The color of the polyp was whitish in all of our cases. In the present cases, close observation by endoscopy revealed that the solitary Peutz-Jeghers-type hamartomatous polyps looked whitish because of the presence of diffusely scattered white spots on the surface of the polyps. Duodenal polyps that exhibit the aforementioned endoscopic characteristics may be diagnosed as Peutz-Jeghers-type hamartomatous polyps and treated by polypectomy because of the malignant potential. | Seiyuu Suzuki Shoji Hirasaki Fusao Ikeda Eiichiro Yumoto Hiromichi Yamane Minoru Matsubara | 2008 | World Journal of Gastroenterology2008，14，6： | 3 |
| 3 | Alpha-fetoprotein before and after pegylated interferon therapy for predicting hepatocellular carcinoma development显示文摘AIM: To investigate factors that accurately predict hepatocellular carcinoma(HCC) development after antiviral therapy in chronic hepatitis C(CHC) patients. METHODS: CHC patients who received pegylated interferon and ribavirin were enrolled in this cohort study that investigated the ability of alpha-fetoprotein(AFP) to predict HCC development after interferon(IFN) therapy. RESULTS: Of 1255 patients enrolled, 665 developed sustained virological response(SVR) during mean follow-up period of 5.4 years. HCC was occurred in 89 patients, and 20 SVR patients were included. Proportional hazard models showed that HCC occurred in SVR patients showing AFP ≥ 5 ng/m L before therapy and in non-SVR patients showing AFP ≥ 5 ng/m L before and 1 year after therapy besides older age, and low platelet counts. SVR patients showing AFP ≥ 5 ng/m L before therapy and no decrease in AFP to < 5 ng/m L 1 year after therapy had significantly higher HCC incidence than non-SVR patients showing AFP ≥ 5 ng/m L before therapy and decreased AFP(P = 0.043). AFP ≥ 5 ng/m L before therapy was significantly associated with low platelet counts and high values of alanine aminotransferase(ALT) in stepwise logistic regression analysis. After age, gender, platelet count, and ALT was matched by propensity score, significantly lower HCC incidence was shown in SVR patients showing AFP < 5 ng/m L before therapy than in those showing AFP ≥ 5 ng/m L.CONCLUSION: The criteria of AFP < 5 ng/m L before and 1 year after IFN therapy is a benefical predictor for HCC development in CHC patients. | Yasuto Takeuchi Fusao Ikeda Toshiya Osawa Yasuyuki Araki Kouichi Takaguchi Youichi Morimoto Noriaki Hashimoto Kousaku Sakaguchi Tatsuro Sakata Masaharu Ando Yasuhiro Makino Shuji Matsumura Hiroki Takayama Hiroyuki Seki Shintarou Nanba Yuki Moritou Tetsuya Yasunaka Hideki Ohnishi Akinobu Takaki Kazuhiro Nouso Yoshiaki Iwasaki Kazuhide Yamamoto | 2015 | World Journal of Hepatology2015，7，19： | 3 |
| 4 | Seroprevalence of Helicobacter pylori in dyspeptic patients and its relationship with HIV infection,ABO blood groups and life style in a university hospital,Northwest Ethiopia显示文摘瞄准:在消化不良的病人之中决定 Helicobacter pylori (H pylori ) 的流行并且估计在 H pylori 感染,血型, HIV 感染和病人的生活方式之间的关系。方法:在基于医院的代表性的研究, Gondar 医院的大学的病人出席门诊病人部门被注册。Socio 人口统计的信息用问询表被收集。浆液用一个商业工具包为 anti-H pylori IgG 抗体被分析。HIV serostatus 被连接酶的免疫吸着剂试金(ELISA ) 决定。Blood grouping 被幻灯片凝集试验执行。结果:215 个消化不良的病人的一个总数在学习被包括。116 个病人(54%) 是女性,(46%) 99 是男性。Anti-H pylori IgG 抗体在重量的单位被检测一 of 184 (85.6%) 病人。流行在 50 年并且在上面的病人是显著地更高的。百分之五个病人被发现是为 HIV 的血清反应阳性的二十个点。没有重要协会为 H pylori 在性别,土佬血型,香的食谱的消费,社会经济的地位和 seropositivity 之间被发现。然而,白酒消费显著地与 H pylori 血清学被联系。结论:H pylori 感染的流行与白酒吸入和老年的历史被联系。象为 H pylori 感染的风险因素的不同饮食,酒精和社会经济的地位的效果需要进一步的学习。 | Feleke Moges Afework Kassu Getahun Mengistu Solomon Adugna Berhanu Andualem Takeshi Nishikawa Fusao Ota | 2006 | World Journal of Gastroenterology2006，12，12： | 2 |
| 5 | Risk factors for recurrence after transarterial chemoembolization for early-stage hepatocellular carcinoma显示文摘 | Hideaki Kinugasa Kazuhiro Nouso Yasuto Takeuchi Tetsuya Yasunaka Hideki Onishi Shin-ichiro Nakamura Hidenori Shiraha Kenji Kuwaki Hiroaki Hagihara Fusao Ikeda Yasuhiro Miyake Akinobu Takaki Kazuhide Yamamoto | 2012 | Journal of Gastroenterology2012，，4： | 2 |
| 6 | Induction and catabolite repression mechanisms of cellulase in fungi 显示文摘 | Manabu S T Fusao T M | 2001 | Journal of Bioscience and Bioengineering2001，92，4： | 1 |
| 7 | Biodegradation or metabolism of bisphenol A: From microorganisms to mammals显示文摘 | Jeong-Hun Kang Yoshiki Katayama Fusao Kondo | 2005 | Toxicology2005，，2： | 1 |
| 8 | Intragranular ferrite nucleation in medium-carbon vanadium steels显示文摘 | Fusao Ishikawa Toshihiko Takahashi Tatsurou Ochi | 1994 | Metallurgical and Materials Transactions A1994，，5： | 1 |
| 9 | Inflammatory fibroid polyp occurring in the transverse colon diagnosed by endoscopic biopsy显示文摘A case of an inflammatory fibroid polyp occurring in the transverse colon and diagnosed by endoscopic biopsy is reported. The patient was an 82-year-old man who visited our hospital for further evaluation of occult blood in stool. The Colonoscopy revealed a small, red, and peduncular polyp, about 6 mm in diameter, in the transverse colon. Histological examination of the biopsy specimen obtained from the polyp revealed proliferation of fibroblasts and infiltration of inflammatory cells such as plasma cells and eosinophils. This polyp was diagnosed as an inflammatory fibroid polyp, which can appear in many different locations throughout gastrointestinal tract, though still rare in the transverse colon. | Shoji Hirasaki Minoru Matsubara Fusao Ikeda Hideaki Taniguchi Seiyuu Suzuki | 2007 | World Journal of Gastroenterology2007，13，27： | 1 |
| 10 | Improved agar diffusion method for detecting residual antimicrobial agents显示文摘 | Chinen Tsai Fusao Kondo | 2001 | Journal of food protection2001，64，3： | 1 |
| 11 | Human exposure to bisphenol A显示文摘 | JEONG H K FUSAO K YOSHIKI K | 2006 | Toxicology2006，226，： | 1 |
| 12 | Induction and catabolite repression mechanisms of cellulase in Fungi显示文摘 | MANABU SUTO FUSAO TOMITA | 2001 | Journal of Bioscience and Bioengineering2001，92，4： | 1 |
| 13 | Determination of Halofuginone and Amprolium in Chicken Muscle and Egg by Liquid Chromatography显示文摘 | Yuzo Yamamoto Fusao Kondo | 2003 | Chromatogr Sci2003，20，7： | 1 |
| 14 | Genetic analysis of the wing-form determination of the small brown planthopper,Laodelphax striatellus (Hemiptera: Delphacidae)显示文摘 | Kiyoko Mori Fusao Nakasuji | 1990 | Researches on Population Ecology1990，，2： | 1 |
| 15 | Prognotic impact of serum follistatin in patients with hepatocellular carcinoma显示文摘 | Takeshi Tomoda Kazuhiro Nouso Koji Miyahara Sayo Kobayashi Hideaki Kinugasa Junki Toyosawa Hiroaki Hagihara Kenji Kuwaki Hideki Onishi Shinichiro Nakamura Fusao Ikeda Yasuhiro Miyake Hidenori Shiraha Akinobu Takaki Kazuhide Yamamoto | 2013 | J Gastroenterol Hepatol2013，，8： | 1 |
| 16 | Establishment and assessment of a rat model of fatigue显示文摘 | Masbki T Fusao N Shigekazu M | 2003 | Neuro Lett2003，352，3： | 1 |
| 17 | Biodegradation or metabolism of bisphenol A: from mieroorganisms to mammals 显示文摘 | Jeong HK Yoshiki K Fusao K | 2006 | Toacicology2006，217，23： | 1 |
| 18 | Liquid chromatographic determination of fluorescent derivative of six sulfonamides in bovine senum and milk显示文摘 | CHIN-EN Tsai FUSAO Kondo | 1995 | AOAC1995，78，3： | 1 |
| 19 | Intragranular ferrite nucleation in medium-carbon vanadium steels显示文摘 | Fusao Ishikawa Toshihiko Takahashi Tatsurou Ochi | 1994 | Metallurgical and Materials Transactions A1994，，5： | 1 |
| 20 | Effect of Cr, Mo and Cu on the atmospheric corrosion resistance of ferritic stainless steels in a coastal environment 显示文摘 | Yoshihiro Yazawa Keiichi Yoshika and Fusao Togashi | 1994 | Kawasaki Steel Technical Report1994，31，： | 1 |
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