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| 1 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | Adrenomedullin and endocrine control of immune cells during pregnancy显示文摘怀孕的免疫学复杂、不完全地听说。在蜕膜并且在胎盘的异常有免疫力的活动被相信在怀孕的疾病起一个作用,例如不孕,流产,胎儿的生长限制和 preeclampsia。这里,我们简短由肽荷尔蒙 adrenomedullin 考察子宫的自然漂亮房间人口和他们的功能的内分泌的控制。在基因动物模型的研究在母亲胎儿的接口揭示了 adrenomedullin 剂量的批评重要性,与从两个的细胞贡献位于适当子宫的感受性,培植并且螺线动脉的脉管的改变下面的必要方面的母亲、胎儿的分隔空间。这些基本卓见进串音在之间内分泌并且在母亲胎儿的接口以内的免疫系统可以最终在临床上复杂的怀孕翻译到功能的更好的理解和 dysregulated adrenomedullin 层次的后果。 | Brooke C Matson Kathleen M Caron | 2014 | Cellular & Molecular Immunology2014，11，5： | 4 |
| 3 | Prediction of delayed graft function using different scoring algorithms: A single-center experience显示文摘AIM To compare the performance of 3 published delayed graftfunction(DGF) calculators that compute the theoretical risk of DGF for each patient.METHODS This single-center,retrospective study included 247 consecutive kidney transplants from a deceased donor.These kidney transplantations were performed at our institution between January 2003 and December 2012.We compared the occurrence of observed DGF in our cohort with the predicted DGF according to three different published calculators. The accuracy of the calculators was evaluated by means of the c-index(receiver operating characteristic curve).RESULTS DGF occurred in 15.3% of the transplants under study.The c index of the Irish calculator provided an area under the curve(AUC) of 0.69 indicating an acceptable level of prediction,in contrast to the poor performance of the Jeldres nomogram(AUC = 0.54) and the Chapal nomogram(AUC = 0.51). With the Irish algorithm the predicted DGF risk and the observed DGF probabilities were close. The mean calculated DGF risk was significantly different between DGF-positive and DGF-negative subjects(P < 0.0001). However,at the level of the individual patient the calculated risk of DGF overlapped very widely with ranges from 10% to 51% for recipients with DGF and from 4% to 56% for those without DGF.The sensitivity,specificity and positive predictive value of a calculated DGF risk ≥ 30% with the Irish nomogram were 32%,91% and 38%. CONCLUSION Predictive models for DGF after kidney transplantation are performant in the population in which they were derived,but less so in external validations. | Magda Michalak Kristien Wouters Erik Fransen Rachel Hellemans Amaryllis H Van Craenenbroeck Marie M Couttenye Bart Bracke Dirk K Ysebaert Vera Hartman Kathleen De Greef Thiery Chapelle Geert Roeyen Gerda Van Beeumen Marie-Paule Emonds Daniel Abramowicz Jean-Louis Bosmans | 2017 | World Journal of Transplantation2017，7，5： | 3 |
| 4 | A prospective two-center study comparing wireless capsule endoscopy with intraoperative enteroscopy in patients with obscure GI bleeding显示文摘 | Dirk Hartmann Harald Schmidt Georg Bolz Dieter Schilling Frank Kinzel Axel Eickhoff Winfried Huschner Kathleen M?ller Ralf Jakobs Peter Reitzig Uwe Weickert Klaus Gellert Harald Schultz Klaus Guenther Hartmut Hollerbuhl Klaus Schoenleben Hans-Joachim Schu | 2005 | Gastrointestinal Endoscopy2005，，7： | 2 |
| 5 | Dynamic capabilities-What are they?显示文摘 | Kathleen M E Jeffrey A M | 2000 | Strategic Management Journal2000，21，： | 1 |
| 6 | The Role of Leisure in Determining Quality of Life: Issues of Content and Measurement 显示文摘 | Kathleen M Lloyd Christopher J Auld | 2002 | Social Indicators Research2002，，57： | 1 |
| 7 | Experience with PICC at a U- niversity Medical Center 显示文摘 | Kathleen M D Christine D C | 1997 | Ioumal of Infusion Nursing1997，20，6： | 1 |
| 8 | Solution-liquid-solid growth of crystalline iii-v semiconductors--An analogy to vapor-liquid-solid growth 显示文摘 | Trentler Timothy J Hickman Kathleen M Goel Subhash C | 1995 | Science1995，270，5243： | 1 |
| 9 | The Mechanism of Action of Multidrug-Resistance-Linked P-Glycoprotein显示文摘 | Zuben E. Sauna Melissa M. Smith Marianna Müller Kathleen M. Kerr Suresh V. Ambudkar | 2001 | Journal of Bioenergetics and Biomembranes2001，，： | 1 |
| 10 | Carley,Computational organizational science and organizational engineering显示文摘 | Kathleen M | 2002 | Simulation Modeling Practice and Theory2002，，10： | 1 |
| 11 | Adnexal masses in pregnancy:surgery compared with observation显示文摘 | Kathleen M Schmeler | 2005 | Am Coll Obstet Gynecol2005，105，： | 1 |
| 12 | Growth and environment in Canada: an empirical analysis 显示文摘 | KATHLEEN M | 2001 | Canadian journal of agricultural economics2001，51，： | 1 |
| 13 | Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence显示文摘 | Chiang-shan Ray L Verica M Kathleen K | 2006 | Drug Alcohol Depend2006，，85： | 1 |
| 14 | Developing Clinical Nures Specialist Practice Competencies显示文摘 | Kathleen M Baldwin Brendal | 2007 | Clinical Nurse Specialist2007，21，6： | 1 |
| 15 | Theoretical and experimental considerations for interpretationof amide I bands in tissue 显示文摘 | KATHLEEN M G LSAN T MARZENA Z K | 2011 | Vibrational Spectroscopy2011，53，1： | 1 |
| 16 | Building Theories From Case Study Research 显示文摘 | Eisenhardt Kathleen M | 1989 | Academy of Management Review1989，14，4： | 1 |
| 17 | Dynamce Capabilities: What are they? 显示文摘 | EISENHARDT KATHLEEN M JEFFREY AMARTIN | 2000 | Strategic Management Journal2000，21，1011： | 1 |
| 18 | Organizational Adaptation 显示文摘 | Kathleen M C | 1998 | Annals of Operations Research1998，，75： | 1 |
| 19 | Strategy as Simple Rules 显示文摘 | KATHLEEN M E DONALD N S | 2001 | Harvard Business Review2001，，1： | 1 |
| 20 | Effects of selenium supplementation on four agricultural crops 显示文摘 | Kathleen M Carvalho Gallardo-Williams Robert F Benson | 2003 | Journal of Agricultural and Food Chemistry2003，51，3： | 1 |
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