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| 1 | The endovascular management of visceral artery aneurysms and pseudoaneurysms显示文摘 | Nirman Tulsyan Vikram S. Kashyap Roy K. Greenberg Timur P. Sarac Daniel G. Clair Gregory Pierce Kenneth Ouriel | 2007 | Journal of Vascular Surgery2007，，2： | 6 |
| 2 | Update on pathology of retinoblastoma显示文摘Retinoblastoma is caused by mutational inactivation of both alleles of the RB1 gene, which maps to chromosome 13 q14 and encodes retinoblastoma protein that acts as a tumor suppressor. Histopathological high-risk features of retinoblastoma are predictive of metastasis or local recurrence. The focus of this update is to emphasize the recent advances in pathology, various molecular key pathways and genome wide approaches for newer potential therapeutic future targets associated with retinoblastoma tumor biology. This review article highlights the new biomarkers expressed by the retinoblastoma tumor for the better survival of patients. | Lata Singh Seema Kashyap | 2018 | International Journal of Ophthalmology(English edition)2018，11，12： | 5 |
| 3 | Extraocular retinoblastoma in Indian children:clinical,imaging and histopathological features显示文摘AIM:To study eyes with extraocular dissemination(EORB),with the following aims:first to establish the mean lag period and to understand various reasons for delayed presentation,second to study their imaging profiles and third to analyze histopathological features of eyes enucleated after neoadjuvant chemotherapy.·METHODS:Prospective study of clinical and imaging features of EORBs(stage Ⅲ and Ⅳ International Retinoblastoma Staging System) presenting to a tertiary eye care centre.Histopathological features of eyes enucleated after receiving neoadjuvant chemotherapy were analyzed.A pictorial illustration of the varied imaging profile of EORB was also presented.·RESULTS:Over a period of one year,97 eyes were diagnosed with retinoblastoma;32 children(36 eyes)(37.1%) had EORB.Mean age 3.6±1.9 years,71.9% males,71.9% unilateral,3.1% with positive family history and40.6% with metastasis.On imaging,there was extrascleral involvement in 22.2%,involvement of orbital part of optic nerve in 33.3%,involvement of central nervous system in 27.8% and orbital wall involvement in2.9% eyes.On histopathological analysis of eyesenucleated after neoadjuvant chemotherapy,25.0% had no residual viable tumour tissue and rest all tumours were poorly differentiated.·CONCLUSION:There are very few human malignancies where definitive treatment is started without any confirmed histopathological diagnosis and imaging plays an important role in diagnosis and appropriate staging of the disease.Chemotherapy has a variable effect on EORB,75.0% of eyes with EORB had residual viable tumour tissue when enucleated after receiving neoadjuvant chemotherapy. | Sumita Sethi Neelam Pushker Seema Kashyap Sanjay Sharma Mridula Mehta Sameer Bakhshi Saurbhi Khurana Supriyo Ghose | 2013 | International Journal of Ophthalmology(English edition)2013，6，4： | 5 |
| 4 | Measuring turbulence in a circulating fluidized bed using PIV techniques显示文摘This study utilized the particle image velocimetry (PIV) technique, non-invasively near the wall, in the developing region, for the measurements of laminar and turbulent properties during circulation of Geldart B type particles in the U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) riser. A novel method was used to measure axial and radial laminar and turbulent solids dispersion coefficients using autocorrelation technique. The instantaneous and hydrodynamic velocities for the solid phase were measured simultaneously in the axial and radial directions using a CCD camera, with the help of a colored rotating transparency. The measured properties, such as laminar and Reynolds stresses, laminar and turbulent granular tempera- tures, laminar and turbulent dispersion coefficients and energy spectra exhibited anisotropy. The mixing in the riser was on the level of clusters. The total granular temperatures were in reasonable agreement with the literature values. However, the axial and radial solids dispersion coefficients measured near the wall were slightly lower than the radially averaged values in the literature. | Mayank Kashyap Benjapon Chalermsinsuwan Dimitri Gidaspow | 2011 | Particuology2011，9，6： | 5 |
| 5 | Checklist for early recognition and treatment of acute illness:International collaboration to improve critica care practice显示文摘Processes to ensure world-wide best-practice for critical care delivery is likely to minimize preventable death, disability and costly complications for any healthcare system's sickest patients, but no large-scale efforts have so far been undertaken towards these goals. The advances in medical informatics and human factors engineering have provided possibility for novel and user-friendly clinical decision support tools that can be applied in a complex and busy hospital setting. To facilitate timely and accurate best-practice delivery in critically ill patients international group of intensive care unit(ICU) physicians and researchers developed a simple decision support tool: Checklist for Early Recognition and Treatment of Acute Illness(CERTAIN). The tool has been refined and tested in high fidelity simulated clinical environment and has been shown to improve performance of clinical providers faced with simulated emergencies. The aim of this international educational intervention is to implement CERTAIN into clinical practice in hospital settings with variable resources(included those in low income countries) and evaluate the impact of the tool on the care processes and patient outcomes. To accomplish our aims, CERTAIN will be uniformly available on either mobile or fixed computing devices(as well as a backup paper version) and applied in a standardized manner in the ICUs of diverse hospitals. To ensure the effectiveness of the proposed intervention, access to CERTAIN is coupled with structured training of bedside ICU providers. | Marija Vukoja Rahul Kashyap Srdjan Gavrilovic Yue Dong Oguz Kilickaya Ognjen Gajic | 2015 | World Journal of Critical Care Medicine2015，4，1： | 5 |
| 6 | 含笑属植物所含化学成分与其生物活性的综述(英文)显示文摘属木兰科的含笑属植物大约有80多个种类,它们大都分布在南亚国家。这些植物被当地人用于治疗各种疾病,如发烧、绞痛、麻风病、眼疾、炎症以及解蝎子毒。从9种含笑属植物中分离出94种化合物,例如倍半萜烯、类固醇、黄酮类、阿扑啡类、苯酚、酯类、生物碱和苯环型化合物等,它们具有抗菌、抗癌以及抗疟原虫活性。本文详细地论述了含笑属植物所含化学成分的生物及化学性能。 | Dinesh Kumar Sunil Kumar Seema Taprial Deepak Kashyap Ajay Kumar Om Prakash | 2012 | 中西医结合学报2012，10，12： | 4 |
| 7 | An Effective Density Based Approach to Detect Complex Data Clusters Using Notion of Neighborhood Difference显示文摘The density based notion for clustering approach is used widely due to its easy implementation and ability to detect arbitrary shaped clusters in the presence of noisy data points without requiring prior knowledge of the number of clusters to be identified. Density-based spatial clustering of applications with noise(DBSCAN) is the first algorithm proposed in the literature that uses density based notion for cluster detection. Since most of the real data set, today contains feature space of adjacent nested clusters,clearly DBSCAN is not suitable to detect variable adjacent density clusters due to the use of global density parameter neighborhood radius N_(rad) and minimum number of points in neighborhood N_(pts). So the efficiency of DBSCAN depends on these initial parameter settings, for DBSCAN to work properly, the neighborhood radius must be less than the distance between two clusters otherwise algorithm merges two clusters and detects them as a single cluster. Through this paper: 1) We have proposed improved version of DBSCAN algorithm to detect clusters of varying density adjacent clusters by using the concept of neighborhood difference and using the notion of density based approach without introducing much additional computational complexity to original DBSCAN algorithm.2) We validated our experimental results using one of our authors recently proposed space density indexing(SDI) internal cluster measure to demonstrate the quality of proposed clustering method. Also our experimental results suggested that proposed method is effective in detecting variable density adjacent nested clusters. | S. Nagaraju Manish Kashyap Mahua Bhattachraya | 2017 | International Journal of Automation and computing2017，14，1： | 4 |
| 8 | Isolation, serotype diversity and antibiogram of Salmonella enterica isolated from different species of poultry in India显示文摘Objective: To study the occurrence and serotype diversity of Salmonella isolates in different species of poultry(chicken, emu and duck) and determine their resistance pattern against various antibiotics of different classes.Methods: About 507 samples comprising 202 caecal contents and 305 fecal samples from chicken, emu and duck were processed for isolation of Salmonella enterica. Salmonellae were isolated and detected by standard protocol of ISO 6579 Amendment 1: Annex D. Genetic confirmation was also made by using 16 S r RNA genus specific PCR. Serotype specific PCR was also done to detect the most common serovars viz. Salmonella Enteritidis, Salmonella Typhimurium and Salmonella Gallinarum. All obtained isolates were subjected to a set of 25 antibiotics to study their antibiogram by using Baeur-Kirby disk diffusion method.Results: Out of 507 samples processed, 32 isolates of Salmonella enterica(18 from caecal contents and 14 from faecal samples) were obtained, of which 24 belonged to 6 different serovars, 6 were untypeable and 2 were rough strains. Salmonella Enteritidis was the most predominant serotype(9), followed by Salmonella Typhimurium(5), Salmonella Virchow(4), Salmonella Gallinarum(3), Salmonella Reading(2) and Salmonella Altona(1). Antibiotic resistance pattern was maximum(100%) to oxacillin, penicillin and clindamycin, followed by ampicillin(68.75%), tetracycline(65.62%), nalidixic acid(56.25%) and colistin(46.87%). High sensitivity of isolates was recorded for chloramphenicol(96.87%) followed by meropenem(84.37%). Conclusions: Occurrence of high proportion of serovars in our study which can cause serious gastroenteritis in humans is a matter of concern. Salmonella Altona has been detected for the first time in India from poultry. This serotype is known to cause serious outbreaks of gastroenteritis in humans. Multidrug resistant isolates were recovered at high percentage which can be attributed to non-judicious use of antibiotics both in prophylaxis and treatment regimen. This observation draws serious attention as poultry serves as an important source of transmission of these multidrug resistant Salmonella serovars to humans. | Irfan Ahmad Mir Sudhir Kumar Kashyap Sunil Maherchandani | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，7： | 3 |
| 9 | Congenital diarrhea in a newborn infant: A case report显示文摘BACKGROUND Microvillus inclusion disease(MVID)is a rare autosomal recessive cause of severe congenital diarrhea with significant morbidity and mortality.Definitive treatment involves bowel transplant.The diagnosis of this condition can be challenging and a few genetic panels are available for the identification of the most common mutations.We present the case of an infant with MVID due to a mutation not reported in the literature before.CASE SUMMARY We report the case of an infant transferred to our institution with severe diarrhea of unknown etiology,failure to thrive,and significant metabolic derangements.An extensive work-up including stool studies for common gastrointestinal pathogens,abdominal ultrasound,esophagogastroduodenoscopy with duodenal biopsy and flexible sigmoidoscopy failed to reveal a diagnosis.Multiple dietary and formula regimens were introduced but all resulted in voluminous diarrhea.She remained on total parenteral nutrition(TPN)for the duration of her hospital stay.Genetic testing was done and she was subsequently found to have a novel mutation in the MYO5B gene[homozygous mutation for MYO5B c.1462del,p.(Ile488Leufs*93)]giving us the diagnosis of MVID.She remains on TPN while awaiting bowel transplant at the time of the compilation of this case report.CONCLUSION We report a novel mutation involved in MVID and highlight the importance of considering this disease when faced with a newborn presenting with life threatening diarrhea.At the time of this publication,232 allelic variations of this gene(MIM#606540)exist in National Center for Biotechnology Information’s database.Our patient’s mutation has not been reported in literature as a cause of MVID. | Mehrin Sadiq Omer Choudry Arun K Kashyap Danitza M Velazquez | 2019 | World Journal of Clinical Pediatrics2019，8，3： | 3 |
| 10 | Clinical considerations for the management of residual diabetes following bariatric surgery显示文摘 | S. R. Kashyap P. Schauer | 2012 | Diabetes, Obesity and Metabolism2012，，9： | 2 |
| 11 | Comparative Analysis of Hepatitis C Recurrence and Fibrosis Progression Between Deceased-Donor and Living-Donor Liver Transplantation: 8-Year Longitudinal Follow-Up显示文摘 | Ashokkumar Jain Ashish Singhal Randeep Kashyap Saman Safadjou Charlotte K. Ryan Mark S. Orloff | 2011 | Transplantation2011，，4： | 2 |
| 12 | 高密度脂蛋白抗动脉粥样硬化功能的丢失与恢复显示文摘 | 秦树存 王家富 KASHYAP M KAMANNA V JIANG X | 2009 | 中国动脉硬化杂志2009，17，7： | 2 |
| 13 | Current status of multidrug resistant tuberculosis in a tertiary care hospital of East Delhi显示文摘 | T Sagar N Singh B Kashyap I Kaur | 2013 | Journal of Postgraduate Medicine2013，，3： | 2 |
| 14 | Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook显示文摘 | Colleen R. Kelly Stacy Kahn Purna Kashyap Loren Laine David Rubin Ashish Atreja Thomas Moore Gary Wu | 2015 | Gastroenterology2015，，： | 2 |
| 15 | Stereotactic Hypofractionated Radiation Therapy as a Bridge to Transplantation for Hepatocellular Carcinoma: Clinical Outcome and Pathologic Correlation显示文摘 | Alan W. Katz Sheema Chawla Zhenhong Qu Randeep Kashyap Michael T. Milano Aram F. Hezel | 2012 | International Journal of Radiation Oncology Biology Physics2012，，3： | 2 |
| 16 | The contemporary management of splenic artery aneurysms显示文摘 | Ryan O. Lakin James F. Bena Timur P. Sarac Samir Shah Leonard P. Krajewski Sunita D. Srivastava Daniel G. Clair Vikram S. Kashyap | 2011 | Journal of Vascular Surgery2011，，： | 2 |
| 17 | Comparison of efficacy of pantoprazole alone versus pantoprazole plus mosapride in therapy of gastroesophageal reflux disease : a randomized trial 显示文摘 | MADAN K AHUJA V KASHYAP PC | 2004 | Dis Esophagus2004，17，4： | 1 |
| 18 | Unsupervised video segmentation and object tracking 显示文摘 | Srinivas Sista Rangasami L Kashyap | 2000 | Computers in Industry2000，42，23： | 1 |
| 19 | A sustained incrase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetcally predisposed to develop type 2 diabetes 显示文摘 | Kashyap S Belfort R Gastaldelli A | 2003 | Diabetes2003，52，： | 1 |
| 20 | Mechanism of action of niacin 显示文摘 | KAMANNA V S KASHYAP M L | 2008 | American Journal of Cardiology2008，101，8： | 1 |
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