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126篇 您的检索式:作者名="Jonathan M L"
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1Portal vein thrombosis, mortality and hepatic decompensation in patients with cirrhosis: A meta-analysis显示文摘AIM: To determine the clinical impact of portal vein thrombosis in terms of both mortality and hepatic decompensations(variceal hemorrhage, ascites, portosystemic encephalopathy) in adult patients with cirrhosis.METHODS: We identified original articles reported through February 2015 in MEDLINE, Scopus, Science Citation Index, AMED, the Cochrane Library, and relevant examples available in the grey literature. Two independent reviewers screened all citations for inclusion criteria and extracted summary data. Random effects odds ratios were calculated to obtain aggregate estimates of effect size across included studies, with 95%CI.RESULTS: A total of 226 citations were identified and reviewed, and 3 studies with 2436 participants were included in the meta-analysis of summary effect. Patients with portal vein thrombosis had an increased risk of mortality(OR = 1.62, 95%CI: 1.11-2.36, P = 0.01). Portal vein thrombosis was associated with an increased risk of ascites(OR = 2.52, 95%CI: 1.63-3.89, P < 0.001). There was insufficient data available to determine the pooled effect on other markers of decompensation including gastroesophageal variceal bleeding or hepatic encephalopathy. CONCLUSION: Portal vein thrombosis appears to increase mortality and ascites, however, the relatively small number of included studies limits more generalizable conclusions. More trials with a direct comparison group are needed.Jonathan G Stine Puja M Shah Scott L Cornella Sean R Rudnick Marwan S Ghabril George J Stukenborg Patrick G Northup 2015World Journal of Hepatology2015,7,27:42
2Abdominal applications of diffusion-weighted magnetic resonance imaging: Where do we stand?显示文摘Diffusion-weighted imaging (DWI) is one of the magnetic resonance imaging (MRI) sequences providing qualitative as well as quantitative information at a cellular level. It has been widely used for various applications in the central nervous system. Over the past decade, various extracranial applications of DWI have been increasingly explored, as it may detect changes even before signal alterations or morphological abnormalities become apparent on other pulse sequences. Initial results from abdominal MRI applications are promising, particularly in oncological settings and for the detection of abscesses. The purpose of this article is to describe the clinically relevant basic concepts of DWI, techniques to perform abdominal DWI, its analysis and applications in abdominal visceral MR imaging, in addition to a brief overview of whole body DWI MRI.Ajaykumar C Morani Khaled M Elsayes Peter S Liu William J Weadock Janio Szklaruk Jonathan Russell Dillman Asra Khan Thomas L Chenevert Hero K Hussain 2013World Journal of Radiology2013,5,3:12
3Colonic manifestations of PTEN hamartoma tumor syndrome: Case series and systematic review显示文摘AIM:To investigate our clinical experience with the colonic manifestations of phosphatase and tensin homolog on chromosome ten(PTEN)hamartoma tumor syndrome(PHTS)and to perform a systematic literature review regarding the same.METHODS:This study was approved by the appropriate institutional review board prior to initiation.A clinical genetics database was searched for patients with PHTS or a component syndrome that received gastrointestinal endoscopy or pathology interpretation at our center.These patient’s records were retrospectively reviewed for clinical characteristics(including family history and genetic testing),endoscopy results and pathology findings.We also performed a systematic review of the literature for case series of PHTS or component syndromes that reported gastrointestinal manifestations and investigations published after consensus diagnostic criteria were established in 1996.These results were compiled and reported.RESULTS:Eight patients from our institution met initial inclusion criteria.Of these,5 patients underwent4.2 colonoscopies at mean age 45.8±10.8 years.All were found to have colon polyps during their clinical course and polyp histology included adenoma,hyperplastic,ganglioneuroma and juvenile.No malignant lesions were identified.Two had multiple histologic types.One patient underwent colectomy due to innumerable polyps and concern for future malignant potential.Systematic literature review of PHTS patients undergoing endoscopy revealed 107 patients receiving colonoscopy at mean age 37.4 years.Colon polyps were noted in92.5%and multiple colon polyp histologies were reported in 53.6%.Common polyp histologies included hyperplastic(43.6%),adenoma(40.4%),hamartoma(38.3%),ganglioneuroma(33%)and inflammatory(24.5%)polyps.Twelve(11.2%)patients had colorectal cancer at mean age 46.7 years(range 35-62).Clinical outcomes secondary to colon polyposis and malignancy were not commonly reported.CONCLUSION:PHTS has a high prevalence of colon polyposis with multiple histologic types.It should be considered a mixed polyposis syndrome.Systematic review found an increased prevalence of colorectal cancer and we recommend initiating colonoscopy for colorectal cancer surveillance at age 35 years.Peter P Stanich Robert Pilarski Jonathan Rock Wendy L Frankel Samer El-Dika Marty M Meyer 2014World Journal of Gastroenterology2014,20,7:5
414 Years of Eosinophilic Esophagitis: Clinical Features and Prognosis显示文摘Jonathan M Spergel Terri F Brown-Whitehorn Janet L Beausoleil James Franciosi Michele Shuker Ritu Verma Chris A Liacouras 2009Journal of Pediatric Gastroenterology and Nutrition2009,,1:2
5Hashash,Nonlinear Ground-Response Analysis of Turkey Flat Shallow Stiff-soil Site to Strong Ground Motion显示文摘Annie 0 L Kwok Jonathan P Stewart Youssef M A 2008Bulletin ot' the Seis- mological Society of America February2008,98,:1
6Comparative nmnagement practices and training: China and Europe 显示文摘JONATHAN L ALEX M 2002Journal of Management Development2002,,2:1
7The epithelial-mesenchymal transition:new insights in signaling,development,and disease显示文摘Jonathan M L Shoukat D Raghu K Erik W T 2006JCB2006,172,7:1
8Changes in pore size distribution upon thermal cycling of TATB-based explosives measured by ultra-small angle X-Ray scattering显示文摘Trevor M W Tony van B Jonathan R I L 2006Propellants Explosives Pyrotechnics2006,31,6:1
9The un-predictable nature of internal tides on continental shelves显示文摘Nash Jonathan D Kelly Samuel M Shroyer Emily L 0,,:1
10Keratocystic Odontogenic Tumour: reclassification of the odontogenic keratocyst from cyst to tumour显示文摘Jonathan M Henry L 2008J Can Dent Assoc2008,74,2:1
11Side resistance of large diameter bored piles socketed into decomposed rock显示文摘Charles W W N Terence L Y Y Jonathan H M L 2001Journal of Geotechnical and Geoenvironmental Engineering ASCE2001,127,8:1
12A survey of active network research显示文摘David L T Jonathan M S David J W 2002IEEE Communications Magazine2002,35,22:1
13GC-MS Screen for the Presence of Melamine, Ammeline, Ammelide, and Cyanuric Acid显示文摘Jonathan J L Gregory E M Kevin J M 2008Laboratory Information Bulletin2008,24,:1
14DHA Exacerbates Experimentally Induced Colitis in SMAD3-/-Mice显示文摘HILLARY L W SARAH J M JONATHAN C 2010FASEB Journal2010,24,:1
15Assessing the potential of yield improvements, through process scrap reduction, for energy and CO2 abatement in the steel and aluminium sectors显示文摘MILFORD Rachel L ALLWOOD J M CULLEN Jonathan M 2011Resources Conservation and Recycling2011,55,12:1
16Using Temperature Modeling to Investigate the Temporal Variability of Riverbed Hydraulic Conductivity During Storm Events 显示文摘Samuel M Jonathan L 2010Journal of Hydrology2010,388,3:1
17Aggregation and deposi- tion characteristics of fullerene nanoparticles in aqueous sys- tems显示文摘Jonathan B Hrl~ne L Wiesner M 2005Journal of Nanoparticle Research2005,,7:1
18Options for achieving a 50% cut in industrial carbon emissions by 2050显示文摘ALLWOOD J M CULLEN Jonathan M MILFORD Rachel L 2010Environmental Science & Technology2010,44,6:1
19Complementary and alternative medications in hepatitis C infection显示文摘Chronic hepatitis C(CHC) infection affects almost 3% of the global population and can lead to cirrhosis, liver failure, and hepatocellular carcinoma in a significant number of those infected. Until recently, the only treatments available were pegylated interferon and ribavirin, which traditionally were not very effective and have considerable side effects. For this reason, interest in complementary and alternative medications(CAM) in the management of hepatitis C has been investigated. Some CAM has demonstrated therapeutic potential in chronic hepatitis C treatment. Unfortunately, some CAM has been shown to have the potential to cause drug-induced liver injury. This article will review and evaluate many of the natural molecules that interact with the hepatitis C virus(HCV) life cycle and discuss their potential use and safety in HCV therapy, as well as highlight some important interactions between medical and complementary treatments.Dina L Halegoua-De Marzio Jonathan M Fenkel 2014World Journal of Hepatology2014,6,1:1
20Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2显示文摘Jonathan O Hosung M Juan L 0,,:1
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