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| 1 | Pancreatic function testing: Here to stay for the 21st century显示文摘The diagnosis of Chronic Pancreatitis (CP) is based on the detection of abnormal structure or function of the diseased pancreas. The pancreatic function tests more accurately determine the presence of CP than tests of structure, especially for early stage disease. The function tests can be divided into two categories: non- invasive and invasive. The invasive 'tube' tests can reliably detect mild, early CP, but are only available at a few referral centers and tend to be poorly tolerated by patients. The non-invasive tests are easy to obtain, but tend to perform poorly in patients with early, mild disease. Therefore, no one test is useful in all clinica situations, and a detailed understanding of the rational, pathophysiologic basis, strengths, and limitations of various tests is needed. This review highlights the role of various pancreatic function tests in the diagnosis of CP including fecal fat analysis, fecal elastase, feca chymotrypsin, serum trypsin, the secretin stimulation test, the cholecystokinin (CCK) stimulation test, the combined secretin-CCK stimulation test, the intraducta and endoscopic secretin stimulation tests, and the functional magnetic resonance imaging of the pancreas after secretin stimulation. | John G Lieb II Peter V Draganov | 2008 | World Journal of Gastroenterology2008,14,20: | 8 |
| 2 | Early successes and late failures in the prevention of post endoscopic retrograde cholangiopancreatography显示文摘Acute pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). The only way to prevent this complication is to avoid an ERCP all together. Because of the risks involved, a careful consideration should be given to the indication for ERCP and the potential risk/benefit ratio of the test. Once a decision to perform an ERCP is made, the procedure should be carried out with meticulous care by an experienced endoscopist, and with a minimum of pancreatic duct opacification. Several pharmacologic agents have been tested, but to date the most important method of reducing post ERCP pancreatitis is the placement of pancreatic stent. Pancreatic stents should be placed in all patients at high risk of this complication such as those undergoing pancreatic sphincterotomy, pancreatic duct manipulation and intervention, and patients with suspected sphincter of Oddi dysfunction. Pancreatic stents should be also considered in patients requiring precut sphincterotomy to gain biliary access. | John G Lieb II Peter V Draganov | 2007 | World Journal of Gastroenterology2007,13,26: | 4 |
| 3 | Endoscopic trans-pterygoid resection of a low-grade cribriform cystadenocarcinoma of the infratemporal fossa显示文摘This article presents a case of low-grade cribriform cystadenocarcinomas(LGCCC),a rare salivary gland tumor manifesting in the infratemporal fossa(ITF).The lesion in this case is unique in its location,histopathology,and management in that the tumor resection was performed using an exclusively endoscopic,endonasal approach.This case highlights the expanding application of endoscopic skull base techniques to address an indolent,slow-growing malignancy of the ITF. | Vikram G.Ramjee Landon J.Massoth John P.Richards II Kibwei A.McKinney | 2020 | World Journal of Otorhinolaryngology-Head and Neck Surgery2020,6,2: | 2 |
| 4 | Multimodality therapy in early-stage neuroendoerine carcinoma of the uterine cervix显示文摘 | David M Boruta II John O | 2001 | Gynecol Oncol2001,81,: | 1 |
| 5 | Multimodality therapy in early stage neuroendocrine earcinoma of the uterine cervix显示文摘 | David M Boruta II John O | 2001 | Gynecol Onco12001,8182,: | 1 |
| 6 | Splenocaval shunt for selec-tive portal decompression 显示文摘 | John II James HT George EP | 1988 | World J Surg1988,12,6: | 1 |
| 7 | Effects of wind-driven rainfall on stemflow generation between codominant tree species with differing crown characteristics 显示文摘 | Van Stan II John T Siegert Courtney M Levia Jr Delphis F | 2011 | Agricultural and Forest Meteorology2011,151,9: | 1 |
| 8 | Laborem Exercens 显示文摘 | John Paul II | 1981 | Origins1981,,11: | 1 |
| 9 | Tethered cord syndrome: a review of the literature from embryology to adult presentation 显示文摘 | Dean A Hertzler II M D John J DePowell M D etc | 2010 | Neumsurg Focus2010,29,: | 1 |
| 10 | Comparing objective feature statistics of speech for classifying clinical depression 显示文摘 | ELLIOT M II MARK C JOHN P | 2004 | IEEE Engi- neering in Medicine and Biology Society2004,26,1: | 1 |
| 11 | Progress Report of a Phase I Study of the Intracerebral Microinfusion of a Recombinant Chimeric Protein Composed of Transforming Growth Factor (TGF)-α and a Mutated form of the Pseudomonas Exotoxin Termed PE-38 (TP-38) for the Treatment of Malignant Brain显示文摘 | John H. Sampson Gamal Akabani Gary E. Archer Darell D. Bigner Mitchel S. Berger Allan H. Friedman Henry S. Friedman James E. Herndon II Sandeep Kunwar Steve Marcus Roger E. McLendon Alison Paolino Kara Penne James Provenzale Jennifer Quinn David A. Reardo | 2003 | Journal of Neuro - Oncology2003,,1: | 1 |
| 12 | Moab' s Living Room 显示文摘 | Berry II John N | 2007 | Library Journal2007,,2: | 1 |
| 13 | Results and conclusions of the National Toxicology Programs rodent carcinogen city studies with sodium fluoride 显示文摘 | Bucher J R Milton R Hejtmancik and John D Toft II | 1991 | International Journal of Cancer1991,48,5: | 1 |
| 14 | Board Composition Form a Strategic Contingency Perspective 显示文摘 | JOHN A PEARCE II SHAKER A ZAHRA | 1992 | Journal of Manage- ment Studies1992,29,4: | 1 |
| 15 | Mycobacterial of infection of animals: pathology and pathogenesis 显示文摘 | Murray E Hines II John MKreeger | 1995 | Laboratory animal science1995,45,: | 1 |
| 16 | Juvenile degenerative disc disease:a report of 76 cases identified by magnetic resonance imaging显示文摘 | John R Dimar II Steven D | 2007 | Spine J2007,7,: | 1 |
| 17 | Multimodality therapy in early - stage neuroendocrine carcinoma of the uterine cervix 显示文摘 | David M Boruta II John O | 2001 | Gynecologic Oncology2001,81,: | 1 |
| 18 | Analysis of musculoskeletal systems in the AnyBody Modeling System 显示文摘 | Michael Damsgard John Rasmussen S II IIen T I Iholm Chris- tensen Egidijus Surma Mark de Zee | 2006 | Simulation Model- ling Practice and Theory2006,14,8: | 1 |
| 19 | First molecular identification of multiple tick‑borne pathogens in livestock within Kassena‑Nankana,Ghana显示文摘The risk of pathogen transmission continues to increase significantly in the presence of tick vectors due to the trade of livestock across countries.In Ghana,there is a lack of data on the incidence of tick-borne pathogens that are of zoonotic and veterinary importance.This study,therefore,aimed to determine the prevalence of such pathogens in livestock using molecular approaches.A total of 276 dry blood spots were collected from cattle(100),sheep(95)and goats(81)in the Kassena-Nankana Districts.The samples were analyzed using Polymerase Chain Reaction(qPCR)and conventional assays and Sanger sequencing that targeted pathogens including Rickettsia,Coxiella,Babesia,Theileria,Ehrlichia and Anaplasma.An overall prevalence of 36.96%was recorded from the livestock DBS,with mixed infections seen in 7.97%samples.Furthermore,the prevalence of infections in livestock was recorded to be 19.21%in sheep,14.13%in cattle,and 3.62%in goats.The pathogens identified were Rickettsia spp.(3.26%),Babesia sp.Lintan(8.70%),Theileria orientalis(2.17%),Theileria parva(0.36%),Anaplasma capra(18.48%),Anaplasma phagocytophilum(1.81%),Anaplasma marginale(3.26%)and Anaplasma ovis(7.25%).This study reports the first molecular identification of the above-mentioned pathogens in livestock in Ghana and highlights the use of dry blood spots in resource-limited settings.In addition,this research provides an update on tick-borne pathogens in Ghana,suggesting risks to livestock production and human health.Further studies will be essential to establish the distribution and epidemiology of these pathogens in Ghana. | Seth Offei Addo Ronald Essah Bentil Kevin Nii Yartey Jane Ansah‑Owusu Eric Behene Selassie Bruku Victor Asoala Suzanne Mate John Asiedu Larbi Philip Kweku Baidoo Michael David Wilson Joseph W.Diclaro II Samuel K.Dadzie | 2023 | Animal Diseases2023,3,1: | 0 |
| 20 | Factors associated with increased incidence of severe toxicities following yttrium-90 resin microspheres in the treatment of hepatic malignancies显示文摘AIM: To further define variables associated with increased incidences of severe toxicities following administration of yttrium-90(^(90)Y) microspheres. METHODS: Fifty-eight patients undergoing 79 treatments were retrospectively assessed for development of clinical and laboratory toxicity incidence following ^(90)Y administration. Severe toxicity events were defined using Common Terminology Criteria for Adverse Events version 4.03 and defined as grade ≥ 3. Univariate logistic regression analyses were used to evaluate the effect of different factors on the incidence of severe toxicity events. Multicollinearity was assessed for all factors with P < 0.1 using Pearson correlation matrices. All factors not excluded due to multicollinearity were included in a multivariate logistic regression model for each measurement of severe toxicity.RESULTS: Severe(grade ≥ 3) toxicities occurred following 21.5% of the 79 treatments included in our analysis. The most common severe laboratory toxicities were severe alkaline phosphatase(17.7%), albumin(12.7%), and total bilirubin(10.1%) toxicities. Decreased pre-treatment albumin(OR = 26.2, P = 0.010) and increased pre-treatment international normalized ratio(INR)(OR = 17.7, P = 0.048) were associated with development of severe hepatic toxicity. Increased pre-treatment aspartate aminotransferase(AST; OR = 7.4, P = 0.025) and decreased pre-treatment hemoglobin(OR = 12.5, P = 0.025) were associated with severe albumin toxicity. Increasing pre-treatment model for end-stage liver disease(MELD) score(OR = 1.8, P = 0.033) was associated with severe total bilirubin toxicity. Colorectal adenocarcinoma histology was associated with severe alkaline phosphatase toxicity(OR = 5.4, P = 0.043).CONCLUSION: Clinicians should carefully consider pre-treatment albumin, INR, AST, hemoglobin, MELD, and colorectal histology when choosing appropriate candidates for ^(90) Y microsphere therapy. | John D Roberson II Andrew M Mc Donald Craig J Baden Chee Paul Lin Rojymon Jacob Omer L Burnett III | 2016 | World Journal of Gastroenterology2016,22,10: | 0 |