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| 1 | Effects of Y on the Microstructure, Mechanical and Bio-corrosion Properties of Mg-Zn-Ca Bulk Metallic Glass显示文摘The micro-alloying effects of Y on the microstructure, mechanical properties, and bio-corrosion behavior of Mg69-xZn27Ca4Yx(x= 0, 1, 2 at.%) alloys were investigated through X-ray diffraction, compressive tests,electrochemical treatments, and immersion tests. The Mg69Zn27Ca4 alloy was found to be absolutely amorphous, and its glass-forming ability decreased with the addition of Y. The Mg68Zn27Ca4Y1 alloy exhibited an ultrahigh compressive strength above 1010 MPa as well as high capacity for plastic strain above 3.1%.Electrochemical and immersion tests revealed that these Y-doped MgeZ neC a alloys had good bio-corrosion resistance in simulated body fluid(SBF) at 37℃. The results of the cytotoxicity test showed high cell viabilities for these alloys, which means good bio-compatibility. | Jingfeng Wang Yang Li Song Huang Yiyun Wei Xingfeng Xi Kaiyong Cai Fusheng Pan | 2014 | Journal of Materials Science & Technology2014，30，12： | 8 |
| 2 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 3 | Microstructure and mechanical properties of large-scale Mg-Gd-Y-Zn-Mn alloys prepared through semi-continuous casting显示文摘Large-scale Mg-8Gd-4Y-1Zn-Mn(wt.%)alloy ingot with a diameter of 315 mm and a length of 2410 mm was prepared through semi-continuous casting.Chemical composition,microstructure and mechanical properties at different locations of the samples with as-cast,T4 and T6 heat-treated states,respectively,were investigated.No obvious macro segregation has been detected in the high-quality alloy ingot.The main eutectic structures at all different locations are composed ofα-Mg,Mg3RE-type,Mg5RE-type and LPSO phases.At the edge of ingot,the unusual casting twins including 10-12 extension twins and 10-11 compression twins were observed due to the intensive internal stress.In T4 heat-treated alloy,the micro segregation was eliminated.The remained phases wereα-Mg and LPSO phase.Combined with the remarkable age-hardening response,T6 samples exhibits improved mechanical properties at ambient temperature,which derives from the dense prismaticβ'precipitates and profuse basalγ'precipitates. | Kui Wang Jingfeng Wang Xiaoxu Dou Yuanding Huang Norbert Hort Sarkis Gavras Shijie Liu Yanwu Cai Jinxing Wang Fusheng Pan | 2020 | Journal of Materials Science & Technology2020，52，17： | 4 |
| 4 | Profiling of hepatocellular carcinoma neoantigens reveals immune microenvironment and clonal evolution related patterns显示文摘Objective: Neoantigens derived from tumor-specific genomic alterations have demonstrated great potential for immunotherapeutic interventions in cancers. However, the comprehensive profile of hepatocellular carcinoma(HCC) neoantigens and their complex interplay with immune microenvironment and tumor evolution have not been fully addressed.Methods: Here we integrated whole exome sequencing data, transcriptome sequencing data and clinical information of 72 primary HCC patients to characterize the HCC neoantigen profile, and systematically explored its interactions with tumor clonal evolution, driver mutations and immune microenvironments.Results: We observed that higher somatic mutation/neoantigen load was associated with better clinical outcomes and HCC patients could be further divided into two subgroups with distinct prognosis based on their neoantigen expression patterns. HCC subgroup with neoantigen expression probability high(NEP-H) showed more aggressive pathologic features including increased incidence of tumor thrombus(P=0.038), higher recurrence rate(P=0.029),more inclined to lack tumor capsule(P=0.026) and with more microsatellite instability sites(P=0.006). In addition,NEP-H subgroup was also characterized by higher chance to be involved in tumor clonal evolution [odds ratio(OR)=46.7, P<0.001]. Gene set enrichment analysis revealed that upregulation of MYC and its targets could suppress immune responses, leading to elevated neoantigen expression proportion in tumor cells. Furthermore, we discovered an immune escape mechanism that tumors could become more inconspicuous by evolving subclones with less immunogenicity. We observed that smaller clonal mutation clusters with higher immunogenicity in tumor were more likely to involve in clonal evolution. Based on identified neoantigen profiles, we also discovered series of neoantigenic hotspot genes, which could serve as potential actionable targets in future.Conclusions: Our results revealed the landscape of HCC neoantigens and discovered two clinically relevant subgroups with distinct neoantigen expression patterns, suggesting the neoantigen expression should be fully considered in future immunotherapeutic interventions. | Zhenli Li Geng Chen Zhixiong Cai Xiuqing Dong Lei He Liman Qiu Yongyi Zeng Xiaolong Liu Jingfeng Liu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 5 | Biomolecule-assisted Solvothermal Synthesis of Bismuth Sulfide Nanorods显示文摘A simple biomolecule-assisted synthetic route has been successfully developed to prepare bismuth sulfide(Bi 2 S 3 ) nanorods under solvothermal conditions.In the synthetic system,pentahydrate bismuth nitrate was employed to supply Bi source and L-cystine was used as sulfide source and complexing agent.The morphology,structure,and phase composition of the as-prepared Bi 2 S 3 products were characterized by X-ray diffraction(XRD),energy dispersion spectroscopy(EDS),X-ray photoelectron spectroscopy(XPS),field-emission scanning electron microscopy(FESEM),transmission electron microscopy(TEM),selected area electron diffraction(SAED),and high-resolution transmission electron microscopy(HRTEM).The experimental results show that the nanorods have uniform diameter of 100-200 nm and length of 2-4 μm.The possible formation mechanism for the bismuth sulfide nanorods was discussed. | Jiasong Zhong Weidong Xian Lijun Liu Xinyu Yan Wen Cai Jingfeng Zhang Xiaojuan Liang | 2010 | Journal of Materials Science & Technology2010，26，5： | 3 |
| 6 | Personality, Per- ceived Environment, and Behavior Systems Related to Future Smoking Intentions among Youths: An Application of Problem-Behavior Theory in Shanghai, China 显示文摘 | Yong Cai Rui Li Jingfeng Zhu | 2015 | PLOS ONE2015，10，3： | 1 |
| 7 | A historical overview of traditional Chinese medicine and ancient Chinese medical ethics显示文摘 | Cai Jingfeng | 1998 | Ethik in der Medizin1998，，1： | 1 |
| 8 | Depression in parents of children with leukemia in southern China accompanied by the prevalence of type D personality显示文摘 | Jie Chen Yang Liu Qingqing Cai Yimin Liu Tong Wang Jingfeng Wang Wei-qing Chen Hui Huang | 2014 | Supportive Care in Cancer2014，，： | 1 |
| 9 | An Optimal Resources Configuration Scheme for Caching-Based Content Distribution in BackhaulLimited Small Cell Networks显示文摘In this paper, we study the problem of resource allocation in small cell networks with distributed caching, that is, how to divide the spectrum resources for backhaul and access in order to improve network performance. We formulate our concerned problem by using multi-dimensional Markov model. Our problem considers that each user may access multiple small cell base stations. We conduct simulation experiments to evaluate the performance of our proposed resource allocation scheme. Our simulation results show that the appropriate spectrum resource allocation is important to improve network performance. | Jingfeng Cai Ronghui Hou Yinghong Ma | 2018 | China Communications2018，15，1： | 1 |
| 10 | Nitrogen contents of rice panicle and paddy by hyperspectral remote sensing 显示文摘 | Tang Yanlin Huang Jingfeng Cai Shaohong | 2007 | Pakistan Journal of Biological Sciences2007，10，24： | 1 |
| 11 | Integration of Traditional Chinese Medicine with Western Medicine-Right or Wrong显示文摘 | Cai Jingfeng | 1988 | Social Science&Medicine1988，27，5： | 1 |
| 12 | The Potential Targets of Chinese Medicines in the Treatment of Parkinson's Disease: Old Wine in New Bottles显示文摘 | Yongjin Zhang Jiaojiao Li Na Wang Jingfeng Ming Zenglin Cai Xiaomin Li | 2016 | Journal of Pharmacy and Pharmacology2016，4，11： | 0 |
| 13 | Expert consensus on organizing the multidisciplinary team(MDT) diagnosis and treatment of hepato-pancreato-biliary diseases in China显示文摘Multidisciplinary team(MDT) discussion has been well established in some European countries and widely carried out in various clinical professional fields(Festen et al.,2021;Fleissig et al.,2006).Many studies have reported the benefits of MDT,including improving survival and quality of cancer care(Munro et al.,2015;Nixon et al.,2021;Tsai et al.,2020). | Binhao Zhang Jian Zhou Weifen Xie Kaishan Tao Shichun Lu Xianglin Yuan Lianxin Liu Weilin Wang Yilei Mao Ping Bie Jingfeng Liu Xinyu Bi Zhiwei Zhang Changhong Liang Jianqiang Cai Zhixiang Jian Yi Lv Peng Zhu Wei Zhang Hongqiang Yang Weiping Zhou Bixiang Zhang Xiaoping Chen | 2022 | Science China(Life Sciences)2022，65，5： | 0 |
| 14 | A Method for Preparing Insecticide of Cabbage Worm Pieris rapae and Its Control Effects显示文摘[Objective]The paper was to study the field control effects of different formulae of plant extracts against cabbage worm Pieris rapae,and to provide a basis for promotion and application of insecticides in production.[Method]With the leaching solution of radix anemones rivularis,Artemisia carvifolia and Nicotiana rustica,and lime and salt water as the materials,field efficacy test was conducted for consecutive two years.[Method]When the mass ratios of radix anemones rivularis mother liquid,A.carvifolia mother liquid,N.rustica mother liquid,lime water and salt water were 4:2:2:1:1:6,4:2:0:1:1:8,4:0:2:1:1:8 and 0:4:2:1:1:8,the control effects were 82.7%-89.8%,38.3%-42.0%,41.0%-45.4%and 52.9%-56.4%,respectively.The insecticide showed the best control effect when the mass ratio of radix anemones rivularis mother liquid,A.carvifolia mother liquid,N.rustica mother liquid,lime water and salt water was 4:2:2:1:1:6.[Conclusion]The optimal formula has good control effect against P.rapae,and the technology has obtained national invention patent. | Xu Xuezhong Hu Jingfeng Yang Hongli Zhang Liqin Lan Mei Liu Jiajia He Jiangming Cai Rongjing Zhu Shiyin Tu Guojing Yang Jingkang Liu Xianmei | 2019 | Plant Diseases and Pests2019，10，4： | 0 |
| 15 | Study on the Shaft-Direct Reduction Process with Cold Bound Pellet显示文摘StudyontheShaft┐DirectReductionProceswithColdBoundPeletQiYuanhong,ZhouYusheng,XuHaichuan,YuJingfeng,CaiAiping①ABSTRACTThemeta... | Qi Yuanhong Zhou Yusheng Xu Haichuan Yu Jingfeng Cai Aiping | 1997 | Journal of Iron and Steel Research(International)1997，4，1： | 0 |
| 16 | A dynamic condition-based maintenance optimization model for mission-oriented system based on inverse Gaussian degradation process显示文摘An effective maintenance policy optimization model can reduce maintenance cost and system operation risk. For mission-oriented systems, the degradation process changes dynamically and is monotonous and irreversible. Meanwhile, the risk of early failure is high. Therefore, this paper proposes a dynamic condition-based maintenance(CBM) optimization model for mission-oriented system based on inverse Gaussian(IG) degradation process. Firstly, the IG process with random drift coefficient is used to describe the degradation process and the relevant probability distributions are obtained. Secondly, the dynamic preventive maintenance threshold(DPMT) function is used to control the early failure risk of the mission-oriented system, and the influence of imperfect preventive maintenance(PM)on the degradation amount and degradation rate is analysed comprehensively. Thirdly, according to the mission availability requirement, the probability formulas of different types of renewal policies are obtained, and the CBM optimization model is constructed. Finally, a numerical example is presented to verify the proposed model. The comparison with the fixed PM threshold model and the sensitivity analysis show the effectiveness and application value of the optimization model. | LI Jingfeng CHEN Yunxiang CAI Zhongyi WANG Zezhou | 2022 | Journal of Systems Engineering and Electronics2022，33，2： | 0 |
| 17 | Tendzin Phuntso's Chemistry of Salts显示文摘An examination of large quantities of Tibetan data for a project entitled 'Alchemy and Alchemic Medicines of Tibet revealed that ancient Tibetan terminology for and classification of inorganic salts have much in common with modern chemistry. This is particularly true of research conducted by Tendzin Phuntso (born in 1672 in Gongjo Count, Chamdo, Tibet) and his representative work, 'gso rig gcesb dus rin chen phreng ba bzugs so'. This work summarizes Tibetan recognition of inorganic salts in chemistry over the course of 1000 years or more, and is of great significance in the world history of science and technolgy. | Zhang Sheng Cai Jingfeng | 2003 | China Tibetology2003，，1： | 0 |
| 18 | Study of Co_2-Supercritical Fluid Extraction(SFE) of Constituents in “Seng-1deng” (SD),a Traditional Tibetan Medicine显示文摘This new, recently developed extracting techniqne, Supercritical Fluid Extraction (SFE), features many advantages in natural product extraction, such as a satisfactory rate of extraction, a high isolation effect, and, when operated entirely free of residual solvents, low cost. | Jiang Jizu Yang Peiquan Liao Zhoukun Zhao Ruobing Ye Kairun Zhang Yinjun Xin Futai Yang Rukui Cai Jingfeng | 2003 | China Tibetology2003，，1： | 0 |
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