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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Low sensitivity in clinical diagnoses of dementia with Lewy bodies显示文摘 | Nelson PT Jicha GA Kryscio RJ | 2010 | J Neurol2010，257，3： | 1 |
| 3 | Investigation and comparison of spray characteristics of pressure-swirl atomizers for a small-sized aircraft turbine engine 显示文摘 | Durdina L Jedelsky J Jicha M | 2014 | Intemational Journal of Heat and MassTransfer2014，78，： | 1 |
| 4 | Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles 'do count' when staging disease severity显示文摘 | Nelson P T Jicha G A Schmitt F A | 2007 | J Neuropathol Exp Neurol2007，66，12： | 1 |
| 5 | Age and apoE associations with complex pathologic features in Alzheimer' s disease 显示文摘 | Jicha GA Parisi JE Dickson DW | 2008 | J Neurol Sci2008，273，12： | 1 |
| 6 | Interleukin 7 generates antitumor cytotoxic T lymphocytes against murine sarcomas with efficacy in cellular adoptive immunotherapy 显示文摘 | Rosenberg S A Jicha D L Mule J J | 1991 | J EXP Med1991，174，12： | 1 |
| 7 | Ductal carcinoma in situ (DCIS): a recised concept显示文摘 | GUMP F E JICHA D L OZELLO L | 1987 | Surgery1987，102，5： | 1 |
| 8 | Development of an effervescent atomizer for industrial burners 显示文摘 | Jedelsky J Jicha M Slama J | 2009 | Energy Fuels2009，23，12： | 1 |
| 9 | Depression, apolipoprotein E, genotype, and the inci-dence of mild cognitive impairment 显示文摘 | Geda YE Knopman DSMrazek DA Jicha GA | 2006 | Jama Neurol- ogy2006，63，3： | 1 |
| 10 | APOE-2 and APOE e4 Correlate with Increased Amyloid Accumulation in Cerebral Vaseu- fature显示文摘 | Nelson P T Pious N M Jicha G A | 2013 | J Neuropathol Exp Neurol2013，72，7： | 1 |
| 11 | Research criteria for the diagnosis of Alzheimer’s disease: revising the NINCDS–ADRDA criteria显示文摘 | Bruno Dubois Howard H Feldman Claudia Jacova Steven T DeKosky Pascale Barberger-Gateau Jeffrey Cummings André Delacourte Douglas Galasko Serge Gauthier Gregory Jicha Kenichi Meguro John O’Brien Florence Pasquier Philippe Robert Martin Rossor Steven Sallow | 2007 | Lancet Neurology2007，，： | 1 |
| 12 | Eulerian-Lagrangian model for traffic dynamics and its impact on operational ventilation of road tunnels显示文摘 | Katolicy J Jicha M | 2005 | Journal of Wind Engineering and Industrial Aerodynamics2005，93，1： | 1 |
| 13 | Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia 显示文摘 | Jicha GA Parisi JE Dickson DW et al | 2006 | Arch Neuro12006，63，5： | 1 |
| 14 | Aberrant expression of mitotic Cdc2/Cyclin B kinase in degenerating neurons of Alzheimer' s disease brains显示文摘 | Vincent I Jicha G Rosado M | 1997 | J Neurosic1997，17，： | 1 |
| 15 | EEG changes in a patient with steroid-responsive encephalopathy associated with an- tibodies to thyroperoxidase ( SREAT, Hashimoto's encephalopa- thy) 显示文摘 | Rodriguez AJ Jicha GA Steeves TD | 2006 | J Clin Neurophysiol2006，23，4： | 1 |
| 16 | Lewy body pathology in normal elderly subjects显示文摘 | Markesbery WR Jicha GA Liu H | 2009 | Neuropathol Exp Neurol2009，68，7： | 1 |
| 17 | Pseudotumor cerebri reversed by cardiac septal defect repair显示文摘 | Jicha GA Suarez GA | 2003 | Neurology2003，60，12： | 1 |
| 18 | Blood serum miRNA:non-invasive biomarkers for Alzheimer's disease显示文摘 | Geekiyanage H Jicha GA Nelson PT | | Experimental Neurology0，，： | 1 |
| 19 | Blood serum miRNA: Non-invasive biomarkers for Alzheimer’s disease显示文摘 | Hirosha Geekiyanage Gregory A. Jicha Peter T. Nelson Christina Chan | 2011 | Experimental Neurology2011，，2： | 1 |
| 20 | Interleukin 7 generates antitumor cytitumor T lymphocytes against murine sarcomas with efficacy in cellular adoptive immunotherapy 显示文摘 | Rosenberg SA Jicha DL Mule P | 1991 | J Exp Med1991，174，12： | 1 |
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