|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Entransy dissipation/loss-based optimization of two-stage organic Rankine cycle(TSORC)with R245fa for geothermal power generation显示文摘Based on organic Rankine cycle(ORC), the two-stage evaporation strategy is adopted to replace the single-stage evaporation to improve the system performance. In order to evaluate the temperature matching of the two-stage evaporation, a theoretical optimization model was established to optimize the two stage organic Rankine cycle(TSORC) based on the entransy theory and thermodynamics, with the ratio of the entransy dissipation rate of the TSORC to that of the ORC as the objective function. This paper aims to illuminate the improving degree of the system performance of the TSORC. The results show that the TSORC enhances the average evaporating temperature, thereby reducing the entransy dissipation rate in the evaporator and the total entransy dissipation rate. The maximal net power output is proportional to the entransy loss rate and inversely proportional to the entransy dissipation rate. However, compared with the ORC, the TSORC can output more power but requires a higher total thermal conductance. Moreover, there exists an optimal intermediate geothermal water temperature(IGWT) to maximize the net power output of the TSORC. The TSORC can be considered in engineering applications. | LI TaiLu YUAN ZhenHe XU Peng ZHU JiaLing | 2016 | Science China(Technological Sciences)2016，59，10： | 10 |
| 2 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation显示文摘Dear Editor,Herpesviridae is a large family of double-stranded DNA(dsDNA)viruses that cause a variety of human diseases ranging from cold sores and chicken pox to congenital defects,blindness and cancer(Chayavichitsilp et al.,2009;Wang et al.,2018).In the past 70 years,substantial advances in our knowledge of the molecular biology of herpesviruses have led to insights into disease pathogenesis and management.However,the mechanism for capsid assembly that requires the ordered packing of about 4,000 protein subunits into the hexons,pentons and triplexes remains elusive.It is still a puzzle how initially identical subunits adopt both hexameric and pentameric conformations in the capsid and select the correct locations needed to form closed shells of the proper size.Biochemical and genetic studies have shown that the portal is involved in initiation of capsid assembly(Newcomb et al.,2005)and functions akin to a DNA-sensor coupling genome-packaging achieved by a genome-packaging machinery-“terminase complex”(Chen et al.,2020;Yunxiang Yang,2020)with icosahedral capsid maturation(Lokareddy et al.,2017).Structural investigations of the herpesvirus portal have proven challenging due to the small size of this dodecamer,which accounts for less than 1%of the total mass of the capsid protein layer and the technical difficulties involved in resolving non-icosahedral components of such large icosahedral viruses(diameter is∼1,250Å).Efforts of many investigators over two decades have made to reconstruct the cryo-electron microscopy(cryo-EM)structure of herpesvirus portal vertex and more recently near-atomic structures of two herpesvirus(herpes simplex virus type 1(HSV-1)and Kaposi’s sarcoma-associated herpesvirus(KSHV))portal vertices were reported(McElwee et al.,2018;Gong et al.,2019;Liu et al.,2019). | Nan Wang Wenyuan Chen Ling Zhu Dongjie Zhu Rui Feng Jialing Wang Bin Zhu Xinzheng Zhang Xiaoqing Chen Xianjie Liu Runbin Yan Dongyao Ni Grace Guoying Zhou Hongrong Liu Zihe Rao Xiangxi Wang | 2020 | Protein & Cell2020，11，5： | 2 |
| 3 | Enhanced tumor homing of pathogen-mimicking liposomes driven by R848 stimulation: A new platform for synergistic oncology therapy显示文摘Although multifarious tumor-targeting modifications of nanoparticulate systems have been attempted in joint efforts by our predecessors,it remains challenging for nanomedicine to traverse physiological barriers involving blood vessels,tissues,and cell barriers to thereafter demonstrate excellent antitumor effects.To further overcome these inherent obstacles,we designed and prepared mycoplasma membrane(MM)-fused liposomes(LPs)with the goal of employing circulating neutrophils with the advantage of inflammatory cytokine-guided autonomous tumor localization to transport nanoparticles.We also utilized in vivo neutrophil activation induced by the liposomal form of the immune activator resiquimod(LPsR848).Fused LPs preparations retained mycoplasma pathogen characteristics and achieved rapid recognition and endocytosis by activated neutrophils stimulated by LPs-R848.The enhanced neutrophil infiltration in homing of the inflammatory tumor microenvironment allowed more nanoparticles to be delivered into solid tumors.Facilitated by the formation of neutrophil extracellular traps(NETs),podophyllotoxin(POD)-loaded MM-fused LPs(MM-LPs-POD)were concomitantly released from neutrophils and subsequently engulfed by tumor cells during inflammation.MM-LPs-POD displayed superior suppression efficacy of tumor growth and lung metastasis in a 4T1 breast tumor model.Overall,such a strategy of pathogen-mimicking nanoparticles hijacking neutrophils in situ combined with enhanced neutrophil infiltration indeed elevates the potential of chemotherapeutics for tumor targeting therapy. | Xiaobei Cheng Pei Yu Xiang Zhou Jiale Zhu Yubao Han Chao Zhang Lingyi Kong | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 2 |
| 4 | Performance of evaluation of Kalina cycle subsystem on geothermal power generation in the oilfield 显示文摘 | Fu Wencheng Zhu Jialing Zhang Wei | 2013 | Applied Thermal Engineering2013，54，2： | 1 |
| 5 | Achieving high yield of Ti3C2Tx MXene few-layer flakes with enhanced pseudocapacior performance by decreasing precursor size显示文摘Ti3C2Tx,a most studied member of MXene family,shows promise as a candidate electrode for pseudocapacitor due to its electronic conductivity and hydrophilic surface.However,the unsatisfactory yield of Ti3C2Tx few-layer flakes significantly restricted it in real applications.Here,we proposed a simple solution to boost the yield of Ti3C2Tx few-layer flakes by decreasing precursor size.When using the small500 mesh Ti3AlC2 powders as raw material,high yield of 65%was successfully achieved.Moreover,the asreceived small flakes also exhibit an enhanced pseudocapacior performance owing to their excellent electrical conductivity,expanded inte rlayer space and more O content on the surface.This work not only sheds light on the cost effective mass production of Ti3C2Tx few-layer flakes,but also provides an efficient solution for the design of MXene electrodes with high pseudocapacior performance. | Jianguang Xu Jiale Zhu Chen Gong Zexin Guan Dan Yang Zhihan Shen Wei Yao Haijiang Wu | 2020 | Chinese Chemical Letters2020，31，4： | 1 |
| 6 | A conceptual model of the Tianjin geothermal system based on isotopic studies显示文摘 | Kun Wang Jialing Zhu | 2001 | Science in China Series E: Technological Sciences2001，，1： | 1 |
| 7 | Performance evaluation of Kalina cycle subsystem on geothermal power generation in the oilfield显示文摘 | Fu Wencheng Zhu Jialing Zhang Wei | 2013 | Applied Thermal Engineering2013，54，2： | 1 |
| 8 | Rif1 interacts with non-canonical polycomb repressive complex PRC1.6 to regulate mouse embryonic stem cells fate potential显示文摘Mouse embryonic stem cells(mESCs)cycle in and out of a transient 2-cell(2C)-like totipotent state,driven by a com-plex genetic circuit involves both the coding and repetitive sections of the genome.While a vast array of regulators,including the multi-functional protein Rif1,has been reported to influence the switch of fate potential,how they act in concert to achieve this cellular plasticity remains elusive.Here,by modularizing the known totipotency regulatory factors,we identify an unprecedented functional connection between Rif1 and the non-canonical polycomb repres-sive complex PRC1.6.Downregulation of the expression of either Rif1 or PRC1.6 subunits imposes similar impacts on the transcriptome of mESCs.The LacO-LacI induced ectopic colocalization assay detects a specific interaction between Rif1 and Pcgf6,bolstering the intactness of the PRC1.6 complex.Chromatin immunoprecipitation followed by sequencing(ChIP-seq)analysis further reveals that Rif1 is required for the accurate targeting of Pcgf6 to a group of genomic loci encompassing many genes involved in the regulation of the 2C-like state.Depletion of Rif1 or Pcgf6 not only activates 2C genes such as Zscan4 and Zfp352,but also derepresses a group of the endogenous retroviral element MERVL,a key marker for totipotency.Collectively,our findings discover that Rif1 can serve as a novel auxiliary component in the PRC1.6 complex to restrain the genetic circuit underlying totipotent fate potential,shedding new mechanistic insights into its function in regulating the cellular plasticity of embryonic stem cells. | Lu Li Pishun Li Jiale Chen Li Li Yunfan Shen Yangzixuan Zhu Jiayi Liu Lu Lv Song Mao Fang Chen Guang Hu Kai Yuan | 2022 | Cell Regeneration2022，11，1： | 1 |
| 9 | Ontology - based information extraction of crop diseases on Chinese web pages 显示文摘 | Jiang Bo Zhu Mengxia Wang Jiale | 2013 | Academy Pub- lisher2013，8，1： | 1 |
| 10 | Design of bionic mole forelimb intelligent row cleaners显示文摘In Northeast China under no-till conditions the amount of maize stubble of the previous year's crop severely limit the quality of sowing operations by unstable operating depth of normal planter row cleaners.Thus,in this study,bionic mole forelimb intelligent row cleaners comprising of a cleaning device and a depth intelligent control system were designed.Via theoretical analysis,computer-based simulation,and test optimized design,the mechanism of bionic cleaners that possessed the forelimb motion morphology and the front claw toe structural morphology of moles was studied,the effects of structural parameters of bionic cleaners on the cleaning quality were clarified.Based on a pressure sensor,a depth intelligent control system was designed,which enhanced the depth stability of the cleaning devices.The types of bionic cleaners were identified by simulation on EDEM software.Then regression equations between different parameters and operation evaluation indices were established,and the optimal parameter combination was identified on Design-Expert software with a rotation radius of 150 mm and a motion deflection angle of 15.8°,at which the cleaning rate was 91.3%.Field tests under the optimal parameter combination showed that bionic cleaners outperformed normal planar cleaners,and the depth intelligent control system could efficiently improve the performance of the row cleaners.The straw cleaning rate of the bionic mole forelimb intelligent row cleaners under total straw mulching fields was 90.9%,which was 21.3%higher than that of normal cleaners,and the ground surfaces after operation satisfied the agricultural requirements of maize no-tillage sowing. | Honglei Jia Qi Wang Dongyan Huang Longtu Zhu Mingwei Li Jiale Zhao | 2019 | International Journal of Agricultural and Biological Engineering2019，12，3： | 1 |
| 11 | MethylationofFOXP3inregulatoryTcellsisrelatedtotheseverityofcoronaryarterydisease显示文摘 | JiaL Zhu L WangJZ etal | 2013 | Atherosclerosis2013，228，2： | 1 |
| 12 | Thermal response test for borehole thermal properties in Tianjin显示文摘 | Fu Wencheng Zhu Jialing Zhang Wei | | 0，，02： | 1 |
| 13 | Differentiation trajectories and biofunctions of symbiotic and un-symbiotic fate cells in root nodules of Medicago truncatula显示文摘The root nodule is a complex symbiotic nitrogen fixation factory,in which cells are highly heterogeneous.However,the differentiation trajectories and interconnection of nodule cells remain largely unknown.In this study,we set up a modified protocol for nodule protoplast preparation and performed a single-cell RNA sequencing profiling of the indeterminate Medicago truncatula nodule.We designated 13 cell clusters with specific expression patterns in 14-day post inoculation nodules and constructed a spatial and functional cellular map based on experimental data and bioinformatic analyses.Pseudotime analysis further revealed that two groups of apical meristematic cells develop into symbiotic and un-symbiotic fate cells along their particular trajectories.Biofunction analysis of each cell cluster revealed their particularity and interrelation,especially that the un-infected cells in nitrogen fixation zone are also involved in nitrogen assimilation by undertaking the asparagine synthesis.Collectively,our data offer an important resource for investigating the mechanism of nodule organogenesis and symbiotic nitrogen fixation. | Qinyi Ye Fugui Zhu Fanghao Sun Tai-Cheng Wang Jiale Wu Peng Liu Chen Shen Jiangli Dong Tao Wang | 2022 | Molecular Plant2022，15，12： | 1 |
| 14 | Surface oxygen-deficient Ti2SC for enhanced lithium-ion uptake显示文摘Recently, MAX phases show great potential in lithium-ion uptake due to their excellent electrical conductivity and unique lamellar-structure accommodating lithium ions. However, the reports about MAX electrodes for lithium-ion battery up to now are relatively low. Herein we report the preparation of surface oxygen-deficient Ti2SC with abundant oxygen vacancies by a facile surface engineering method. When using as a lithium storage anode, this oxygen-deficient Ti2SC delivers a high capacity of 350 m Ah/g at a current density of 400 m A/g as well as excellent rate performance, doubling the capacity compared to that of Ti2SC without oxygen vacancies. Confirmed by electrochemical impedance spectroscopy(EIS)and kinetic mechanism analyses, after reducing surface oxides and generation of oxygen vacancies, the as-received Ti2SC exhibits higher electrical conductivity and faster lithium ion diffusion. Thus this work offers a facial and effective strategy of optimizing the surface structure of MAX phases, further to achieve an enhanced lithium-ion uptake for lithium-ion batteries or capacitors. | Jianguang Xu Hongyan Hang Chen Chen Boman Li Jiale Zhu Wei Yao | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
| 15 | All-organic nanocomposite dielectrics contained with polymer dots for high-temperature capacitive energy storage显示文摘High-temperature polymer dielectrics with high energy density are urgently needed for capacitive energy storage fields.However,the huge conduction loss at elevated temperatures makes the capacitive performance of polymers degrade sharply,limiting the application of them.Herein,the polymer dots(PDs)with high-electron-affinity were introduced into high-temperature polymers to prepare all-organic nanocomposite dielectrics by solution casting.It is found that polymer dots capture injected electrons via strong electrostatic attraction and impede charges transport and accumulation inside composites,thus reducing leakage current density and improving high-temperature energy storage performance.Consequently,the high-temperature capacitance performance of nanocomposites was improved significantly and reached over 2.5 times that of the pristine polymers,e.g.,the energy density of polyetherimide(PEI)/PD reached 3.24 J·cm^(-3)with excellent electrical fatigue reliability over 20,000 times.This work addresses the current problem of poor discharged energy density of polymer dielectrics at high temperatures with a simple and universal method. | Jiale Ding Wenhan Xu Xuanbo Zhu Zheng Liu Yunhe Zhang Zhenhua Jiang | 2023 | Nano Research2023，16，7： | 0 |
| 16 | A Method for Identifying Channeling Paths in Low-Permeability Fractured Reservoirs显示文摘Often oilfield fractured horizontal wells produce water flowing in multiple directions.In this study,a method to identify such channeling paths is developed.The dual-medium model is based on the principle of inter-well connectivity and considers the flow characteristics and related channeling terms.The Lorentz curve is drawn to qualitatively discern the geological type of the low-permeability fractured reservoir and determine the channeling direction and size.The practical application of such an approach to a sample oilfield shows that it can accurately identify the channeling paths of the considered low-permeability fractured reservoir and predict production performances according to the inter-well connectivity model.As a result,early detection of water channeling becomes possible,paving the way to real-time production system optimization in low-permeability fractured reservoirs. | Zhenfeng Zhao Bin Li Zubo Su Lijing Chang Hongzheng Zhu Ming Liu Jialing Ma Fan Wang Qianwan Li | 2022 | Fluid Dynamics & Materials Processing2022，18，6： | 0 |
| 17 | Visualization of Bulk Polymerization by Fluorescent Probe with Aggregation-induced Emission Characteristics显示文摘Bulk polymerization is one of the most commonly used techniques in polymer preparing due to its relatively simple process,low cost and easier aftertreatment of the product[1-5].Bulk polymerization has attracted much attention in both academic researches and industrial productions of commodity polymers,such as poly(methyl methacrylate)(PMMA)[6]and polystyrene(PS)[7].During the process of bulk polymerization,an autoacceleration phenomenon,which is also referred to as the gel or Trommsdorff effect,is often observed[8]. | NIU Junfeng SUN Haiya XIA Housheng ZHU Yinbang CHEN Jialing ZHU Chengye BAI Wei | 2022 | Chemical Research in Chinese Universities2022，38，2： | 0 |
| 18 | Systemic delivery of microRNA for treatment of brain ischemia显示文摘Brain ischemia is the second leading cause of death and the third leading cause of disability in the world.Systemic delivery of microRNA,a class of molecules that regulate the expression of cellular proteins associated with angiogenesis,cell growth,proliferation and differentiation,holds great promise for the treatment of brain ischemia.However,their therapeutic efficacy has been hampered by poor delivery efficiency of microRNA.We report herein a platform technology based on microRNA nanocapsules,which enables their effective delivery to the disease sites in the brain.Exemplified by microRNA-21,intravenous injection of the nanocapsules into a rat model of cerebral ischemia could effectively ameliorate the infarct volume,neurological deficit and histopathological severity. | Chaoyong Liu Jing Wen Dai Li Hongzhao Qi Lina Nih Jialin Zhu Duo Xu Yu Ren Shanshan Zhang Donglin Han Huanhuan Jia Junhu Zhou Meng Qin Jialing Wu Xubo Yuan Ji Liu Jin Zhao Chunsheng Kang Yunfeng Lu | 2021 | Nano Research2021，14，9： | 0 |
| 19 | Enhanced electrical,mechanical and tribological properties of Cu-Cr-Zr alloys by continuous extrusion forming and subsequent aging treatment显示文摘As a promising material for the new generation of high-speed railway contact wires,the comprehensive optimization of the electrical conductivity,strength,hardness and wear resistance of the Cu-Cr-Zr alloy has received extensive attention.In this paper,a high-performance Cu-1Cr-0.1Zr alloy with an ultimate tensile strength of 599.1 MPa,a uniform elongation of 8.6%,a microhardness of 195.7 HV_(0.2) and an electrical conductivity of 80.07%IACS was achieved by the continuous extrusion forming(CEF)and subsequent peak-aging treatment.The grain refinement strengthening,dislocation strengthening and precipitation strengthening are identified to be responsible for the excellent electrical and mechanical properties of Cu-Cr-Zr alloy.The wear behavior of Cu-Cr-Zr alloy was investigated by examining the evolution of worn surface morphology and subsurface microstructure.The microhardness(H)and reduced elastic modulus(E_(r))of the subsurface below the worn surface measured by nanoindentation were calculated to gage the tribological performance of Cu-Cr-Zr alloy.Results show that the continuously extruded and subsequently peak-aged specimen has the best wear resistance,which indicates that the tribological properties of CuCr-Zr alloy strongly depend on its strength and hardness.It can be concluded that the CEF and subsequent aging treatment process provides a new and high-efficiency procedure for the continuous preparation of Cu-Cr-Zr alloys. | Zhe Shen Zhongze Lin Peijian Shi Jiale Zhu Tianxiang Zheng Biao Ding Yifeng Guo Yunbo Zhong | 2022 | Journal of Materials Science & Technology2022，，15： | 0 |
| 20 | PD-L1-driven efficient enrichment and elimination of circulating cancer cells by magnetic MoSe_(2) nanosheet显示文摘Circulating tumor cells(CTCs)are important biomarkers in the development and progression of lung cancer because they can reach other organs through the blood circulation and form distant metastases,exacerbating lung cancer progression.The presence of CTCs is also the main reason for the failure of nanomedicine-based lung cancer treatments.Therefore,magnetic MoSe_(2) nanosheets loaded with programmed death-ligand 1(PD-L1),named PD-L1-MFP NS,were employed here to precisely capture lung cancer CTCs in the blood circulation through the tumor-targeting effect of PD-L1 killing CTCs with highly effective photothermal therapy(PTT).In addition,by increasing the expression of cytomegalovirus UL16-binding protein(ULBP)ligands on tumor cells,the PD-L1-MFP NS further activated natural killer(NK)cells and triggered NK cell-induced cancer immunotherapy,thereby enhancing the overall tumor-killing effect.In summary,this material designed to capture CTCs provides a substantial advancement for personalized PTT-triggered immunotherapy and has great clinical translational potential. | Hongjie Huang Binhua Zou Shanlin Zhu Xingchen Zhang Jiale Huang Jinlin Wang Xiaoling Li Tianfeng Chen | 2024 | Nano Research2024，17，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员