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| 1 | Burn injury induces histopathological changes and cellproliferation in liver of rats显示文摘AIM: To investigate effects of severe burn injury(BI) in rat liver through the histopathological and inflammatory markers analysis. METHODS: Forty-two male Wistar rats were distributed into two groups, control(C) and subjected to scald BI(SBI). The animals were euthanized one, four and 14 d post sham or 45% of the total body surface BI. Liver fragments were submitted to histopathological, morphoquantitative(hepatocyte area and cell density), ciclooxigenase-2(COX-2) immunoexpression, and gene expression [real-time polymerase chain reaction for tumor necrosis factor(TNF)-α, inducible nitric oxide synthase(i NOS) and caspase-3] methods. RESULTS: Histopathological findings showed inflammatory process in all periods investigated and hepatocyte degeneration added to increased amount of connective tissue 14 d post injury. Hepatocyte area, the density of binucleated hepatocytes and density of sinusoidal cells of SBI groups were increased when compared with control. COX-2 immunoexpression was stronger in SBI groups. No differences were found in TNF-α, i NOS and caspase-3 gene expression. CONCLUSION: BI induces histopathological changes, upregulation of COX-2 immunoexpression, and cell proliferation in liver of rats. | Jeferson Andre Bortolin Hananiah Tardivo Quintana Tabata de Carvalho Tome Flavia Andressa Pidone Ribeiro Daniel Araki Ribeiro Flavia de Oliveira | 2016 | World Journal of Hepatology2016，8，6： | 4 |
| 2 | Long term effects of manure, charcoal and mineral fertilization on crop production and fertility on a highly weathered Central Amazonian upland soil显示文摘 | Christoph Steiner Wenceslau G. Teixeira Johannes Lehmann Thomas Nehls Jeferson Luis Vasconcelos Macêdo Winfried E. H. Blum Wolfgang Zech | 2007 | Plant and Soil2007，，1： | 2 |
| 3 | Burn Injury Induces Skeletal Muscle Degeneration, Inflammatory Host Response, and Oxidative Stress in Wistar Rats显示文摘 | Nathalia Trasmonte da Silva Hananiah Tardivo Quintana Jeferson André Bortolin Daniel Araki Ribeiro Flavia de Oliveira | 2015 | Journal of Burn Care & Research2015，，3： | 2 |
| 4 | Long term effects of manure, charcoal and mineral fertilization on crop production and fertility on a highly weathered Central Amazonian upland soil显示文摘 | Christoph Steiner Wenceslau G. Teixeira Johannes Lehmann Thomas Nehls Jeferson Luis Vasconcelos Macêdo Winfried E. H. Blum Wolfgang Zech | 2007 | Plant and Soil (-)2007，，1： | 2 |
| 5 | Energy Efficiency and Reduction of CO2 Emission through 2015:The Brazilian Cement Industry显示文摘 | JEFERSON B S MAURICIO T T | | 0，，： | 1 |
| 6 | Vaccines for preventing influenza in heahhy children显示文摘 | Jeferson T Rjvetti A HamdenA | 2008 | Cochrane Database Syst-Rev2008，16，00： | 1 |
| 7 | Vaccines for preventing influenza in healthy adults 显示文摘 | Jeferson TO Rivem D Di Pietrantonj C | 2007 | Cochrane Database SystRev2007，18，00： | 1 |
| 8 | Vaccines for preventing influenza in the elderly显示文摘 | Rivetti D Jeferson T Thomas R | 2006 | Cochrane Database Syst-Rev2006，19，3： | 1 |
| 9 | Cell phenontype speciic kinetics of expression of intratracheally injected manganese superoxide dismutase-plasmid/liposomes(MnSOD-PL) during lung radioprotective gene therapy显示文摘 | Epperly MW Guo HL Jeferson M | | 0，，06： | 1 |
| 10 | Regulation of protein synthesis byinsulin显示文摘 | Kimball SR Vary TC Jeferson LS | | 0，，： | 1 |
| 11 | An electrochemical-based fuel-cell model suitable for electrical engineering automation approach显示文摘 | JEFERSON C M FELIX A F LUCIANE N C | 2004 | lEEE Tran of Industrial Electronics2004，51，5： | 1 |
| 12 | Sensitivity analysis of the modelling parameters used in simulation of proton exchange membrane fuel cells 显示文摘 | Jeferson M C Marcelo G S | 2005 | Transactions on energy conversion2005，20，1： | 1 |
| 13 | Use of 8-hydroxyquinoline-chitosan chelating resin in an automated on-line preeoneentration system for determination of zinc(Ⅱ)by F AAS显示文摘 | Jeferson Schneider Carletto Kalya Cravo Di Pietro Roux Heloisa Franea Maltez | 2008 | Journal of Hazardous Materials2008，157，1： | 1 |
| 14 | Line optical detection in the transient state of extrusion polymer blending and reactive proces sing显示文摘 | Tomas Jeferson A Melo Sebastiao V Canevarolo | 2005 | Polymer Engineering and Science2005，45，1： | 1 |
| 15 | Automatic camera control in virtual environments augmented using multiple sparse videos显示文摘 | Jeferson R Silva Thiago T Santos Carlos H Morimoto | 2011 | Computers&Graphics2011，35，2： | 1 |
| 16 | First report of Aeeda lichff (Kerfer) (prostigmata: Eriophyidae) on litchi trees in Brazil显示文摘 | Adalton R Jeferson L D C M M6rio E S | 2010 | Revista Brasileira De Fruticultura2010，32，2： | 1 |
| 17 | Sensitivity analysis of the modeling parameters used in simulation of proton exchange membrane fuel cells显示文摘 | Jeferson M C Felix A F Vladimir A P | 2005 | IEEE Transactions on Energy Conversion2005，20，1： | 1 |
| 18 | Use of 8-hydroxyquinoline- chitosan chelating resin in an automated on-line preconcen- tration system for determination of zinc ( 1I ) by FAAS 显示文摘 | Jeferson Schneider Carletto Kalya Cravo Di Pietro Roux Heloisa Frana Maltez | 2008 | Journal of Hazardous Materials2008，157，1： | 1 |
| 19 | Prospects for tourism: a practitioner's view 显示文摘 | Jeferson A | 1995 | Tourism Management1995，16，2： | 1 |
| 20 | Estradiol,progesterone, and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary'in vitro and in vivo 显示文摘 | Chen Y Jeferson WN Newbold RR | 2007 | Endocrinology2007，148，8： | 1 |
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