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您的检索式：作者名="Javiera Torres"
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| 1 | Non-invasive diagnosis of gastric mucosal atrophy in an asymptomatic population with high prevalence of gastric cancer显示文摘AIM: To validate a non-invasive method to detect gastric mucosal atrophy in a Chilean population with high prevalence of gastric cancer and a poor survival rate. METHODS: We first determined the optimal cut-off level of serum pepsinogen (PG)-1, PG-1/PG-2 ratio and 17-gastrin in 31 voluntary symptomatic patients (mean age: 66.1 years), of them 61% had histologically confirmed gastric atrophy. Then, in a population-based sample of 536 healthy individuals (209 residents in counties with higher relative risk and 327 residents in counties with lower relative risk for gastric cancer), we measured serum anti-H pylori antibodies, PG and 17-gastrin and estimated their risk of gastric cancer. RESULTS: We found that serum PG-1 < 61.5 μg/L, PG-1/PG-2 ratio < 2.2 and 17-gastrin > 13.3 pmol/L had a high specificity (91%-100%) and a fair sensitivity (56%-78%) to detect corpus-predominant atrophy. Based on low serum PG-1 and PG-1/PG-2 ratio together as diagnostic criteria, 12.5% of the asymptomatic subjects had corpus-predominant atrophy (0% of those under 25 years and 20.2% over 65 years old). The frequency of gastric atrophy was similar (12% vs 13%) but H pylori infection rate was slightly higher (77% vs 71%) in the high-risk compared to the low-risk counties. Based on their estimated gastric cancer risk, individuals were classified as: low-risk group (no H pylori infection and no atrophy; n = 115; 21.4%); moderate-risk group(H pylori infection but no atrophy; n = 354, 66.0%); and high-risk group (gastric atrophy, with or without H pylori infection; n = 67, 12.5%). The high-risk group was significantly older (mean age: 61.9 ± 13.3 years), more frequently men and less educated as compared with the low-risk group. CONCLUSION: We propose to concentrate on an upper gastrointestinal endoscopy for detection of early gastric cancer in the high-risk group. This intervention model could improve the poor prognosis of gastric cancer in Chile. | Antonio Rollan Catterina Ferreccio Alessandra Gederlini Carolina Serrano Javiera Torres Paul Harris | 2006 | World Journal of Gastroenterology2006，12，44： | 14 |
| 2 | Sleeve Gastrectomy as Treatment for Severe Obesity after Orthotopic Liver Transplantation显示文摘 | Jean M. Butte Nicolás Devaud Nicolás P. Jarufe Camilo Boza Gustavo Pérez Javiera Torres Rosa M. Pérez-Ayuso Marco Arrese Jorge Martínez | 2007 | Obesity Surgery2007，，11： | 1 |
| 3 | Helicobacter pylori Gastritis in Children Is Associated With a Regulatory T-Cell Response显示文摘 | Paul R. Harris Shelton W. Wright Carolina Serrano Francisca Riera Ignacio Duarte Javiera Torres Alfredo Pe?a Antonio Rollán Paola Viviani Ernesto Guiraldes Julia M. Schmitz Robin G. Lorenz Lea Novak Lesley E. Smythies Phillip D. Smith | 2008 | Gastroenterology2008，，2： | 1 |
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