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| 1 | Systematic review of dynamization vs exchange nailing for delayed/non-union femoral fractures显示文摘AIM To analyze the literature on efficacy of dynamamization vs exchange nailing in treatment of delayed and nonunion femur fractures.METHODS Ultimately, 31 peer-reviewed articles with 644 exchanged nailing patients and 131 dynamization patients were identified and analyzed. The following key words were inputted in different combinations in order to search the field of publications in its entirety: 'nonunion', 'delayed union', 'ununited', 'femur fracture', 'femoral fracture', 'exchange nailing', 'dynaiz(s)ation', 'secondary nailing', 'dynamic', 'static', and 'nail revision'. The initial search yielded over 150 results, and was refined based on the inclusion criteria: Only studies reporting on humans, non-unions and delayed unions, and the usage of exchange nailing and/or dynamization as a secondary treatment after failed IM nailing. The resulting 66 articles were obtained through online journal access. The results were filtered further based on the exclusion criteria: No articles that failed to report overall union rates, differentiate between success rates of their reported techniques, or articles that analyzed less than 5 patients. RESULTS Exchange nailing lead to fracture union in 84.785% of patients compared to the 66.412% of dynamization with statistically comparable durations until union(5.193 ± 2.310 mo and 4.769 ± 1.986 mo respectively). Dynamically locking exchange nails resulted in an average union time of 5.208 ± 2.475 mo compared to 5.149 ± 2.366 mo(P = 0.8682) in statically locked exchange nails. The overall union rate of the two procedures, statically and dynamically locked exchange nailing yielded union rates of 84.259% and 82.381% respectively. Therefore, there was no significant difference between the different locking methods of exchange nailing for union rate or time to union at a significance value of P < 0.05. The analysis showed exchange nailing to be the more successful choice in the treatment of femoral non-unions in respect to its higher success rate(491/567 EN, 24/57 dynam, P < 0.0001). However, there was no significant difference between the success rates of the two procedures for delayed union fractures(25/27 EN, 45/55 dynam, P = 0.3299). Nevertheless, dynamization was more efficient in the treatment of delayed unions(at rates comparable to exchange nailing) than in the treatment of non-unions.CONCLUSION In conclusion, after examination of factors, dynamization is recommended treatment of delayed femur fractures, while exchange nailing is the treatment of choice for non-unions. | Jacob E Vaughn Ronit V Shah Tarek Samman Jacob Stirton Jiayong Liu Nabil A Ebraheim | 2018 | World Journal of Orthopedics2018，9，7： | 5 |
| 2 | Which Time-to-Peak Threshold Best Identifies Penumbral Flow?: A Comparison of Perfusion-Weighted Magnetic Resonance Imaging and Positron Emission Tomography in Acute Ischemic Stroke显示文摘 | J Sobesky O Zaro Weber F -G. Lehnhardt V Hesselmann A Thiel C Dohmen A Jacobs M Neveling W -D. Heiss | 2004 | Stroke2004，，12： | 2 |
| 3 | Cardiac arrest and cardiop- ulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries : a statement for healthcare professionals from a task force of the International Liai- son Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Coun- cil, New Zealand Resuscitation Council, Heart and Stroke Foun- dation of Canada, InterAmerican Heart Foundation, Resuscitation Councils of Southern Mriea) 显示文摘 | Jacobs I Nadkarni V Bahr J | 2004 | Circulation2004，110，2： | 1 |
| 4 | Human papiUomavirus is a necessary cause of invasive cervical cancer worldwide显示文摘 | WALBOOMERS J M M JACOBS M V MANOS M M | 1999 | J Pathol1999，189，： | 1 |
| 5 | Sc and Zn-catalyzed synthesis of cyclic carbonates from CO2 and epoxides 显示文摘 | ION A PARVULESCU V JACOBS P | 2009 | Applied Catalysis (A) : General2009，363，： | 1 |
| 6 | Submucosal purse-string suture as a treatment of leakage around the indwelling voice prosthesis显示文摘 | JACOBS K DELAERE P R VANDER POORTEN V L | 2008 | Head Neck2008，30，： | 1 |
| 7 | Genetic algorithms for product design显示文摘 | Balakrishnan P V Jacob V S | | 0，，08： | 1 |
| 8 | OMEGA EP high-energy petawatt laser: progress and prospects显示文摘 | D N Maywar J H Kelly L J Waxer S F B Morse I A Begishev J Bromage C Dorrer J L Edwards L Folnsbee M J Guardalben S D Jacobs R Jungquist T J Kessler R W Kidder B E Kruschwitz S J Loucks J R Marciante R L McCrory D D Meyerhofer A V Okishev J B Oliver G Pien | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 9 | A genetics-based hybrid scheduler for generating static schedules in flexible manufacturing contexts显示文摘 | JACOB V S PAKATH R ZAVERI J S | 1993 | IEEE Transaction on Systems Man and Cybernetics1993，23，4： | 1 |
| 10 | Environmentally acceptable specialty lubricantsan interpretation of the environmental regulations of North Sea(world)显示文摘 | Stringfellow W D Jacobs N L Hendriks R V | 1993 | NLGI Spokesman1993，57，9： | 1 |
| 11 | Thermal expansion anomalies and spontaneous magnetostriction in R2 Felt C intermetallic compounds 显示文摘 | Andreev A V De Boer F R Jacobs T H | 1991 | Physica B1991，175，： | 1 |
| 12 | ACC/AHA guidelines for the martagement of patients with ST-elevation myocardial infarction-executive summary:port of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of patients with Acute Myocardial Infarction) 显示文摘 | Antman EM Anbe DT Armstrong PW Bates ER Green LA Hand M Hochman JS Krumholz HM Kushner FG Lamas GA Mullany CJ Ornato JP pearle DL Sloan MA Smith SCJr Alpert JS Anderson JL Faxon DP Fuster V Gibbons RJ Gregoratos G Halperin JL Hiratzka LF Hunt SA Jacobs AK American College of Cardiology American Heart Association Task Force on Practice Guidelines | 2004 | Circulation2004，110，5： | 1 |
| 13 | Fabrication and properties of fiber and particulate-reinforced SiC matrix composites obtained with (A)HPCS as the matrix source显示文摘 | Jacobs J M Intermnte L V | 1997 | Key Engineering Material1997，127，： | 1 |
| 14 | The Arabidopsis tludiana dhdps gene encoding dihydrodipicollnate synthase, key enzyme of lysine biosynthesis, is expressed in a cell-specific manner显示文摘 | Vauterin M Frankard V Jacobs M | 1999 | Plant Molecular Biology1999，39，4： | 1 |
| 15 | Male breast cane- er,age and sex chromosome aneuploidy显示文摘 | Jacobs PA Maloney V Cooke R | 2013 | Br J Cancer2013，108，4： | 1 |
| 16 | Multislice CT and CT angiography for non-invasive evaluation of bronchopulmonary sequestration显示文摘 | Ahmed M Jacob V Yogi TJ | 2004 | Eur Radiol2004，14，11： | 1 |
| 17 | Classic intrafascial supracervical hysterectomy (CISH) : 10 - year experience显示文摘 | Morrison J Jacobs V | 2006 | JSLS2006，10，1： | 1 |
| 18 | Human papillomavirus is a necessary cause of invasive cervical cancer worldwide显示文摘 | Walboomers J M Jacobs M V Manos M M | 1999 | J Pathol1999，189，1： | 1 |
| 19 | Human papillomavirus is a necessary cause of invasive cervical cancer worldwide显示文摘 | WALBOOMERS J M JACOBS M V MANOS M M | 1999 | J Pathol1999，189，： | 1 |
| 20 | Improved synthesis of graphene oxide 显示文摘 | Daniela C Marcano Dmitry V Kosynkin Jacob M Berlin | 2010 | ACS Nano2010，4，8： | 1 |
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