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| 1 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 2 | Adenoma detection with cap-assisted colonoscopy versus regular colonoscopy: a randomised controlled trial显示文摘 | Thomas R de Wijkerslooth Esther M Stoop Patrick M Bossuyt Elisabeth M H Mathus-Vliegen Jan Dees Kristien M A J Tytgat Monique E van Leerdam Paul Fockens Ernst J Kuipers Evelien Dekker | 2012 | Gut2012，，10： | 3 |
| 3 | Ethanol metabolism and its effects on the intestinal epithelial barrier显示文摘 | Elhaseen E Elamin Ad A Masclee Jan Dekker Daisy M Jonkers | 2013 | Nutr Rev2013，，7： | 3 |
| 4 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 5 | Microstructural analysis of pineal volume using trueFISP imaging显示文摘AIM:To determine the spectrum of pineal microstructures (solid/cystic parts) in a large clinical population using a high-resolution 3D-T2-weighted sequence. METHODS:A total of 347 patients enrolled for cranial magnetic resonance imaging were randomly included in this study. Written informed consent was obtained from all patients. The exclusion criteria were artifacts or mass lesions prohibiting evaluation of the pineal gland in any of the sequences. True-FISP-3D-imaging (1.5-T, isotropic voxel 0.9 mm) was performed in 347 adults (55.4 ± 18.1 years). Pineal gland volume (PGV), cystic volume, and parenchyma volume (cysts exclud- ed) were measured manually. RESULTS:Overall, 40.3% of pineal glands were cystic. The median PGV was 54.6 mm 3 (78.33 ± 89.0 mm 3 ), the median cystic volume was 5.4 mm 3 (15.8 ± 37.2mm 3 ), and the median parenchyma volume was 53.6 mm 3 (71.9 ± 66.7 mm 3 ). In cystic glands, the standard deviation of the PGV was substantially higher than in solid glands (98% vs 58% of the mean). PGV declined with age (r = -0.130, P = 0.016). CONCLUSION:The high interindividual volume variation is mainly related to cysts. Pineal parenchyma volume decreased slightly with age, whereas genderrelated effects appear to be negligible. | Jan M Bumb Marc A Brockmann Christoph Groden Ingo Nolteb | 2013 | World Journal of Radiology2013，5，4： | 2 |
| 6 | 二甲双胍长期治疗2型糖尿病患者以及维生素B12缺乏的危险性:随机安慰剂对照研究(摘要)显示文摘目的 研究接受胰岛素治疗的2型糖尿病患者中,二甲双胍所致维生素B12缺乏(〈150pmol/L)、低浓度维生素B12(150—220pmol/L)的发生率,以及叶酸和同型半胱氨酸的浓度。 | Jolien de Jager Adriaan Kooy Philippe Lehert Michiel G Wulffele Jan van der Kolk Daniel Bets Joop Verburg Ab J M Donker Coen D A Stehouwer 许翎岭(译) | 2010 | 英国医学杂志中文版2010，13，5： | 2 |
| 7 | Environmental pollution due to tanneries and leather manufacturing units in NWFP显示文摘 | Khawaja M A Jan M R Ahmed I 1995 | 1995 | J Anal & Envl Chem1995，3，1： | 1 |
| 8 | Effect of Ca on the solubility and molecular size distribution of DOC and Cu binding in soil solution samples显示文摘 | Romkens Paul F A M Jan Dolfing | 1998 | Environ Sci Technol1998，32，： | 1 |
| 9 | Brick kiln exhaust as a source of polycyclic aromatic hydrocarbons (PAHs) in the surrounding soil and plants: A case study from the city of Peshawar显示文摘 | Jan F A Khan S lshaq M | 2013 | Arabian Journal of Geosciences2013，7，1： | 1 |
| 10 | Color Selection and Location Selection in ERPs:Differences,Similarities and ' Neural Specificity'显示文摘 | Jan J L Albertus A W Lambertus J M | 1998 | Biological Psychology1998，48，： | 1 |
| 11 | Speed-sensorless direct torque control of induction motors using an adaptive flux observer显示文摘 | JEHUDI M JAN A | 2000 | IEEE Transactions on Industry Application2000，36，3： | 1 |
| 12 | An overview of sigma-Delta eonverters显示文摘 | Pervez M A Henrik V S Jan VDS | 1996 | IEEE1996，13，1： | 1 |
| 13 | Impact of Pulsed electric field treatment on the recovery and quality of plant oils 显示文摘 | Guder jan M To P S Angersbach A | 2004 | Journal of Food Engineering2004，26，： | 1 |
| 14 | Constructal optimization of nonuniformly distributed tree-shaped flow structures for conduction 显示文摘 | BE JAN A | 2001 | Int J Heat Mass Transfer2001，44，22： | 1 |
| 15 | Clinical value of polysomnography显示文摘 | Douglas N J Thomas S Jan M A | 1992 | Lancet1992，339，8789： | 1 |
| 16 | PRISMA-DB A parallel main memory relational DBMS 显示文摘 | PETER M G A CAREL A V D B JAN F | 1992 | IEEE Transactions on Knowledge and Data Engineering1992，4，6： | 1 |
| 17 | Explaining the acceptance and use of government Internet services: A multivariate analysis of 2006Survey data in the Netherlands显示文摘 | Jan A G Dijk M van Peters O | 2008 | Government Information Quarterly2008，25，3： | 1 |
| 18 | Effect of particle size of chemical mechanical polishing slurries for enhanced polishing with minimal defects显示文摘 | Basim G B A dler J J M aha Jan U | 2000 | Elecrochem Soc2000，147，35： | 1 |
| 19 | The fate of nitrogen functionalities in coal during pyrolysis and combustion显示文摘 | Marek A Wo Jan R P Jacob A M | 1995 | Fuel1995，74，4： | 1 |
| 20 | A method of studying carbon particle distribution in paint films显示文摘 | MOZETIC M ZALAR A PAN JAN P BELEM PEJOVNIK S GRMEK R | 2000 | Thin Sol Films2000，376，11： | 1 |
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