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| 1 | DRASTIC地下水脆弱性评价方法及其应用——以泰国清迈盆地为例显示文摘针对泰国清迈盆地的特点和区域特色,利用DRASTIC方法对该地区的地下水脆弱性进行了定量评价,并绘制了地下水脆弱性分区图,对清迈盆地今后制订地下水资源管理、土地利用、环境保护及城市规划等政策措施具有重要的指导作用。该方法同样适用于我国广大地区的地下水脆弱性评价。 | 张保祥 万力 JADE Julawong | 2007 | 水资源保护2007，23，2： | 23 |
| 2 | 四川新津宝墩遗址的植硅体分析显示文摘农业是文明产生的深厚基础。成都平原是长江上游地区文明起源的中心,探讨其史前农业的经济形态一直是学术界关心的热点问题。本文拟对新津宝墩遗址的文化层剖面及两处灰坑的样品进行植硅体分析,并结合浮选结果,以期探讨宝墩遗址农业经济状况。研究结果表明,宝墩文化层中,存在大量具有驯化特征的产于水稻叶秆的扇型和横排双裂片型(哑铃型)植硅体以及产于水稻稃壳的双峰型植硅体,同时还存在少量黍稃壳植硅体碎片。水稻扇型植硅体多呈典型的驯化形态,总体尺寸较大,其测量数据符合粳稻植硅体特征。这表明宝墩先民的经济结构是以稻作农业为主,兼有粟作农业。 | 陈涛 江章华 何锟宇 杨洋 Jade d’Alpoim GUEDES 蒋洪恩 胡耀武 王昌燧 吴妍 | 2015 | 人类学学报2015，34，2： | 11 |
| 3 | Gene Expression Profiling of Human Epidermal Keratinocytes in Simulated Microgravity and Recovery Cultures显示文摘Simulated microgravity (SMG) bioreactors and DNA microarray technology are powerful tools to identify 'space genes' that play key roles in cellular response to microgravity. We applied these biotechnology tools to investigate SMG and post-SMG recovery effects on human epidermal keratinocytes by exposing cells to SMG for 3, 4, 9, and 10 d using the high aspect ratio vessel bioreactor followed by recovery culturing for 15, 50, and 60 d in normal gravity. As a result, we identified 162 differentially expressed genes, 32 of which were 'center genes' that were most consistently affected in the time course experiments. Eleven of the center genes were from the integrated stress response pathways and were coordinately down-regulated. Another seven of the center genes, which are all metallothionein MT-I and MT-II isoforms, were coordinately up-regulated. In addition, HLA-G, a key gene in cellular immune response suppression, was found to be significantly up-regulated during the recovery phase. Overall, more than 80% of the differentially expressed genes from the shorter exposures (≤4 d) recovered in 15 d; for longer (≥9 d) exposures, more than 50 d were needed to recover to the impact level of shorter exposures. The data indicated that shorter SMG exposure duration would lead to quicker and more complete recovery from the microgravity effect. | Jade Q. Clement Shareen M. Lacy Bobby L. Wilson | 2008 | Genomics, Proteomics & Bioinformatics2008，6，1： | 4 |
| 4 | Synaptic dysfunction in Alzheimer's disease:the effects of amyloid beta on synaptic vesicle dynamics as a novel target for therapeutic intervention显示文摘The most prevalent form of dementia in the elderly is Alzheimer's disease.A significant contributing factor to the progression of the disease appears to be the progressive accumulation of amyloid-β42(Aβ42),a small hydrophobic peptide.Unfortunately,attempts to develop therapies targeting the accumulation of Aβ42 have not been successful to treat or even slow down the disease.It is possible that this failure is an indication that targeting downstream effects rather than the accumulation of the peptide itself might be a more effective approach.The accumulation of Aβ42 seems to affect various aspects of physiological cell functions.In this review,we provide an overview of the evidence that implicates Aβ42 in synaptic dysfunction,with a focus on how it contributes to defects in synaptic vesicle dynamics and neurotransmitter release.We discuss data that provide new insights on the Aβ42 induced pathology of Alzheimer's disease and a more detailed understanding of its contribution to the synaptic deficiencies that are associated with the early stages of the disease.Although the precise mechanisms that trigger synaptic dysfunction are still under investigation,the available data so far has enabled us to put forward a model that could be used as a guide to generate new therapeutic targets for pharmaceutical intervention. | Jade Marsh Pavlos Alifragis | 2018 | Neural Regeneration Research2018，13，4： | 4 |
| 5 | Post-inflammatory acquired atresia of the external auditory canal显示文摘Acquired atresia of the external auditory canal(EAC)is a rare cause of conductive hearing loss.It has been traditionally classified into 4 categories:traumatic,post-operative,neoplastic and inflammatory.Post-inflammatory acquired auditory canal atresia is thought to be the result of chronic and repetitive infectious bouts affecting the auditory canal.Nevertheless,the underlying pathophysiology of this disorder is yet to be fully elucidated.Current data fail to clearly state the impact that certain underlying systemic disorders may have on the EAC.The possible association to metabolic disturbances such as iron deficiency is also emphasized.In the light of these findings,this analysis can be used to improve the classification of this entity thereby standardizing the assessment of therapeutic approaches. | Michel Kmeid Jade Nehme | 2019 | Journal of Otology2019，14，4： | 3 |
| 6 | Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome显示文摘 | Yu Chen Weifeng Liang Shigui Yang Nanping Wu Hainv Gao Jifang Sheng Hangping Yao Jianer Wo Qiang Fang Dawei Cui Yongcheng Li Xing Yao Yuntao Zhang Haibo Wu Shufa Zheng Hongyan Diao Shichang Xia Yanjun Zhang Kwok-Hung Chan Hoi-Wah Tsoi Jade Lee-Lee Teng We | 2013 | 2013 (9881)2013，，9881： | 2 |
| 7 | Cilia in cell signaling and human disorders显示文摘One of the most widespread cellular organelles in nature is cilium,which is found in many unicellular and multicellular organisms.Formerly thought to be a mostly vestigial organelle,the cilium has been discovered in the past several decades to play critical motile and sensory roles involved in normal organogenesis during development.The role of cilia has also been implicated in an ever increasing array of seemingly unrelated human diseases,including blindness,kidney cysts,neural tube defects and obesity.In this article we review some of the recent developments in research on cilia,and how defects in ciliogenesis and function can give rise to developmental disorders and disease. | Neil A.Duldulao Jade Li Zhaoxia Sun | 2010 | Protein & Cell2010，1，8： | 2 |
| 8 | Feature extraction and denoising using kernel PCA 显示文摘 | Jade A M Srikanth B Jayaraman V K | 2003 | Chemical Engineering Science2003，58，19： | 1 |
| 9 | Bio-Oil from Hydro-Liquefaction of Bagasse in Supercritical Ethanol显示文摘 | JADE CHUMPOO PATTARAPAN PRASASSARAKICH | 2010 | Energy & Fuels2010，24，： | 1 |
| 10 | Age and gender variations in the management of ischaemic stroke in China显示文摘 | Yining H Ji-Guang W Jade WW | 2010 | International J Stroke2010，5，： | 1 |
| 11 | Evidence-based analysis: postoperative gastric bleeding: etiology and prevention显示文摘 | Jade S. Hiramoto Jonathan P. Terdiman Jeffrey A. Norton | 2003 | Surgical Oncology2003，，1： | 1 |
| 12 | Characterization of strength and deformation of jointed rock mass based on statistical analysis 显示文摘 | Jade S Sitharam T G | 2003 | International Journal of Geotechnics2003，3，12： | 1 |
| 13 | Support vector machines:a useful tool for process engineering applications显示文摘 | Agarwal M Jade A M | 2003 | Chemical Engineering Process2003，99，1： | 1 |
| 14 | Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome显示文摘 | Yu Chen Weifeng Liang Shigui Yang Nanping Wu Hainv Gao Jifang Sheng Hangping Yao Jianer Wo Qiang Fang Dawei Cui Yongcheng Li Xing Yao Yuntao Zhang Haibo Wu Shufa Zheng Hongyan Diao Shichang Xia Yanjun Zhang Kwok-Hung Chan Hoi-Wah Tsoi Jade Lee-Lee Teng We | 2013 | The Lancet2013，，9881： | 1 |
| 15 | Differentiation through customer involvement in production or delivery 显示文摘 | Song Jade H Carl R Adams | 1993 | Journal of Consumer Marketing1993，10，2： | 1 |
| 16 | Strength, balance, and the modifying effects of obesity and knee pain: results from the Observational Arthritis Study in Seniors (oasis)显示文摘 | Jadelis K Miller ME Ettinger WH Jr | 2001 | J Am Geriatr Soc2001，49，： | 1 |
| 17 | Factors associated with prehospi- tal delays in the presentation of acute stroke in urban China 显示文摘 | Haiqiang J Sainan Z Jade W | 2012 | Stroke2012，43，2： | 1 |
| 18 | The course of PTSD symptoms following military training aci- dents and brief psychosoeial interventions 显示文摘 | Jade E | 2003 | Pets Individ Differ2003，35，： | 1 |
| 19 | Strength,balance, and the modifying efects of obesity and knee pain:resuits from the Observational Arthritis Study in Seniors (oasis ) 显示文摘 | Jadelis K Miller M E Ettinger W H Jr | 2001 | J Am Geriatr Soc2001，49，7： | 1 |
| 20 | Her Vision Was Tied Down显示文摘 | E. Ulysses Dorotheo Rosa A. Tang Hasan M. Bahrani Jade S. Schiffman M. Tariq Bhatti Stephen B. Lewis | 2005 | Survey of Ophthalmology2005，，6： | 1 |
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