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| 1 | Spatiotemporal microRNA profile in peripheral nerve regeneration:miR-138 targets vimentin and inhibits Schwann cell migration and proliferation显示文摘While the peripheral nervous system has regenerative ability,restoration of sufficient function remains a challenge.Vimentin has been shown to be localized in axonal growth fronts and associated with nerve regeneration,including myelination,neuroplasticity,kinase signaling in nerve axoplasm,and cell migration;however,the mechanisms regulating its expression within Schwann cell(SC) remain unexplored.The aim of this study was to profile the spatial and temporal expression profile of micro RNA(mi RNA) in a regenerating rat sciatic nerve after transection,and explore the potential role of mi R-138-5 p targeting vimentin in SC proliferation and migration.A rat sciatic nerve transection model,utilizing a polyethylene nerve guide,was used to investigate mi RNA expression at 7,14,30,60,and 90 days during nerve regeneration.Relative levels of mi RNA expression were determined using microarray analysis and subsequently validated with quantitative real-time polymerase chain reaction.In vitro assays were conducted with cultured Schwann cells transfected with mi RNA mimics and assessed for migratory and proliferative potential.The top seven dysregulated mi RNAs reported in this study have been implicated in cell migration elsewhere,and GO and KEGG analyses predicted activities essential to wound healing.Transfection of one of these,mi RNA-138-5 p,into SCs reduced cell migration and proliferation.mi R-138-5 p has been shown to directly target vimentin in cancer cells,and the luciferase assay performed here in rat Schwann cells confirmed it.These results detail a role of mi R-138-5 p in rat peripheral nerve regeneration and expand on reports of it as an important regulator in the peripheral nervous system. | Travis B.Sullivan Litchfield C.Robert Patrick A.Teebagy Shannon E.Morgan Evan W.Beatty Bryan J.Cicuto Peter K.Nowd Kimberly M.Rieger-Christ David J.Bryan | 2018 | Neural Regeneration Research2018，13，7： | 6 |
| 2 | Estimation of tropical forest structural characteristics using large-footprint lidar显示文摘 | Jason B Drake Ralph O Dubayah David B Clark Robert G Knox J.Bryan Blair Michelle A Hofton Robin L Chazdon John F Weishampel Steve Prince | 2001 | Remote Sensing of Environment2001，，2： | 1 |
| 3 | Use of Large-Footprint Scanning Airborne Lidar To Estimate Forest Stand Characteristics in the Western Cascades of Oregon显示文摘 | Joseph E. Means Steven A. Acker David J. Harding J.Bryan Blair Michael A. Lefsky Warren B. Cohen Mark E. Harmon W.Arthur McKee | 1999 | Remote Sensing of Environment1999，，3： | 1 |
| 4 | Seashore paspalum (Paspalum vaginatum Sw.) performance under shade in multi-environment trials显示文摘Shade caused by trees or buildings can affect the quality and growth of turfgrasses.Thus,breeding for shade tolerance is an essential component of most turfgrass improvement programs.The objective of this study was to evaluate the performance of seashore paspalum(Paspalum vaginatum Sw.)breeding lines under shade in multi-environment trials.Germplasm sources were 20 lines from the University of Georgia seashore paspalum breeding program and two checks,the cultivars'SeaDwarf'and'SeaStar'.Field trials were conducted from 2016 to 2019 under shade structures designed to reduce ambient sunlight at three locations:Citra(FL),Tifton(GA),and Raleigh(NC).The response variables evaluated were percent living ground cover(%GC),dark green color index(DGCI),canopy height(CH)and turfgrass quality(TQ).Data were analyzed by mixed model approaches using ASReml-R,and the t-statistics were used to group the entries.Significant genetic variances were observed in the single-location-repeated-measures analysis for CH and DGCI at Citra and Tifton,%GC at Citra,and TQ at Raleigh.Spearman correlations of the predicted values for entries between locations ranged from low to moderate,with the exception of between Citra and Tifton(0.76)for CH.There were a few breeding lines with superior performance to the entry average for all traits for which the entry variance was significant.In conclusion,genetic variability was observed for all traits and superior seashore paspalum breeding lines for multiple traits were identified under shade. | Beatriz Tome Gouveia Paul Raymer Brian M.Schwartz Esteban F.Rios Kevin E.Kenworthy J.Bryan Unruh Charles Fontanier Esdras M.Carbajal Jason Kruse Natasha K.Restuccia Susana R.Milla-Lewis | 2021 | Grass Research2021，1，1： | 0 |
| 5 | 以人群为基础的生物监测:纽约市有机磷和拟除虫菊酯类杀虫剂暴露显示文摘[背景]有机磷类和拟除虫菊酯类是两类美国最常见的杀虫剂。这些杀虫剂广泛用于控制纽约市建筑物里的虫害,所导致的杀虫剂暴露可能比比在欠城市化的环境中更高。[目的]估计纽约市杀虫剂暴露的参考值,并确定人口学特征和行为特征以预测暴露。[方法]2004年纽约市健康与营养调查是一项在人群基础上的横断面研究,研究对像为≥20岁的成年人。检测883名参加者的尿中有机磷代谢产物[二甲基磷酸酯(DMP)、二甲基硫代磷酸酯(DMTP)、二甲基二硫代磷酸酯、二乙基磷酸酯、二乙基硫代磷酸酯和二乙基二硫代磷酸酯]的浓度,以及1 452名参加者的尿中拟除虫菊酯类代谢产物[3-苯氧基苯甲酸(3-PBA)、反式-3-(2,2-二氯乙烯基)-2,2-二甲基环丙烷-1-羧酸(反式DCCA)、4-氟-3-苯氧基苯甲酸和顺式-3-(2,2-二溴乙烯基)-2,2-二甲基环丙烷-1-羧酸]的浓度。使用多元线性回归在不同的预测因子类别中估计总二烃基磷酸盐(ΣDAP)的最小二乘几何平均值和3-PBA浓度。[结果]二甲基有机磷代谢产物的第95百分位浓度最高(DMP和DMTP分别为87.4μg/L和74.7μg/L)。拟除虫菊酯类代谢物中测得的最高第95百分位浓度分别为3-PBA和反式-DCCA(分别为5.23μg/L和5.94μg/L)。ΣDAP浓度随着年龄增加而增加,在非西班牙裔白人或黑人中较西班牙裔/族裔高,在专业使用杀虫剂者中较高,也随水果的消费频率增加而增加;ΣDAP浓度随非绿色蔬菜消费增加而下降。在各预测因子类别中尿3-PBA浓度几何均数的绝对差值都太小而无意义。[结论]纽约市拟除虫菊酯类和有机磷二甲酯类暴露水平估值均高于美国的整体水平,因此在制定杀虫剂的使用法规时,一定要考虑城市中虫害与杀虫剂负荷。 | Wendy McKelvey J.Bryan Jacobson Daniel Kass Dana Boyd Barr Mark Davis Antonia M.Calafat Kenneth M.Aldous | 2014 | 环境与职业医学2014，31，4： | 0 |
| 6 | Mobilizing Crop Biodiversity显示文摘Over the past 70 years,the world has witnessed extraordinary growth in crop productivity,enabled by a suite of technological advances,including higher yielding crop varieties,improved farm management,synthetic agrochemicals,and agricultural mechanization.While this'Green Revolution'intensified crop production,and is credited with reducing famine and malnutrition,its benefits were accompanied by several undesirable collateral effects(Pingali,2012).These include a narrowing of agricultural biodiversity,stemming from increased monoculture and greater reliance on a smaller number of crops and crop varieties for the majority of our calories.This reduction in diversity has created vulnerabilities to pest and disease epidemics,climate variation,and ultimately to human health(Harlan,1972). | Susan McCouch Zahra Katy Navabi Michael Abberton Noelle L.Anglin Rosa Lia Barbieri Michael Baum Kirstin Bett Helen Booker Gerald L.Brown Glenn J.Bryan Luigi Cattivelli David Charest Kellye Eversole Marcelo Freitas Kioumars Ghamkhar Dario Grattipaglia Robert Henry Maria Cleria Valadares Inglis Tofazzal Islam Zakaria Kehel Paul J.Kersey Graham J.King Stephen Kresovich Emily Marden Sean Mayes Marie Noelle Ndjiondjiop Henry T.Nguyen Samuel Rezende Paiva Roberto Papa Peter W.B.Phillips Awais Rasheed Christopher Richards Mathieu Flouard Maria Jose Amstalden Sampaio Uwe Scholz Paul D.Shaw Brad Sherman S.Evan Staton Nils Stein Jan Svensson Mark Tester Jose Francisco Montenegro Valls Rajeev Varshney Stephen Visscher Eric von Wettberg Robbie Waugh Peter Wenzl Loren H.Rieseberg | 2020 | Molecular Plant2020，13，10： | 0 |
| 7 | 加拿大Algoma公司新建的2^#无缝钢管机组显示文摘<正> Algonla钢公司新建一套无缝钢管机组是1979年开始筹划的,其目的是将石油管的直径范围下限扩大到48.3毫米(1.9英寸)。该公司原有的1~#机组虽然可以生产小到114亳米的钢管,但它破适宜的产品直径是177.8~324毫米。新建的这套机组将生产尺寸范围为48.3~177.8毫米的产品。 | J.Bryan Code 李长穆 | 1989 | 湖南冶金1989，，2： | 0 |
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