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| 1 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 3 |
| 2 | Bone morphogenetic protein-2 causes commitmem and differentiation in C3H10T1/2 and 3T3 cells显示文摘 | Wang EA Israel DI Kelly S | 1993 | Growth Factors1993，9，： | 1 |
| 3 | Expression and characterization of bone morphogenetic protein-2 in Chinese hamster ovary cells显示文摘 | Israel DI Nove J | 1992 | Growth Factors1992，7，2： | 1 |
| 4 | Spontaneous post-anesthetic tremor does not resemble thermoregulatory shivering显示文摘 | Sessler DI Israel D Pozos RS | | 0，，06： | 1 |
| 5 | Heterodimeric bone morphogenetic proteins show enhanced activity in vitro显示文摘 | Israel DI Nove J Kems KM | 1996 | Growth Factors1996，13，： | 1 |
| 6 | Expression and characterization of bone morphogenetic protein - 2 in Chinese hamster cells 显示文摘 | Israel DI Nove J Kerns KM | 1992 | Growth Factors1992，7，2： | 1 |
| 7 | Heterodimeric bone morphogenetic proteins show enhanced activity in vitro and in vivo显示文摘 | Israel DI Nove J Kerns KM Kaufman RJ Rosen V Cox KA Wozney JM | | 0，，： | 1 |
| 8 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 1 |
| 9 | Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells显示文摘 | Wang EA Israel DI Kelly S | 1993 | Growth Factors1993，9，： | 1 |
| 10 | Expression and characterization of bonemorphogenetic protein 2 in Chinese hamster ovary cells显示文摘 | ISRAEL DI NOVE J KERNS KM | 1992 | Growth Factors1992，7，： | 1 |
| 11 | Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T12 and 3T3 cells显示文摘 | Wang EA Israel Di Kelly S | 1993 | Growth Factors1993，9，： | 1 |
| 12 | Heterodimerie bone morpho- genetic proteins show enhanced activity in vitro and in vivo 显示文摘 | Israel DI Nove J Kerns KM | 1996 | Growth Factors1996，13，34： | 1 |
| 13 | Heterodimeric bone morphogenetic proteins show enhanced activity in vitro and in vivo显示文摘 | Israel DI Nove J Kerns KM | 1996 | Growth Factors1996，13，34： | 1 |
| 14 | Spontaneous post - anesthetic tremor does not resemble thermoregulatory shivering显示文摘 | Sessler DI Israel D Pozos RS | 1988 | Anesthesiol- ogy1988，68，： | 1 |
| 15 | Spontaneous post-anesthetic tremor does not resemble thermoregulatory shivering显示文摘 | Sessler DI Israel D Pozos RS | 1988 | Anesthesiology1988，68，6： | 1 |
| 16 | Expression and characterization of bone morphogenetic protein - 1 in Chinese hamster ovary cells显示文摘 | Israel DI Nove J Kevns KM | 1992 | Growth factor1992，7，： | 1 |
| 17 | Tribological behavior of shape-specific microplate-enriched synovial fluids on a linear two-axis tribometer显示文摘Nano-and micro-particles are being increasingly used to tune interfacial frictional properties in diverse applications,from friction modifiers in industrial lubrication to enhanced biological fluids in human osteoarthritic joints.Here,we assessed the tribological properties of a simulated synovial fluid enriched with non-spherical,poly lactic-co-glycolic acid(PLGA)microparticles(μPL)that have been previously demonstrated for the pharmacological management of osteoarthritis(OA).Three different μPL configurations were fabricated presenting a 20μm×20μm square base and a thickness of 5μm(thin,5H μPL),10μm(10H μPL),and 20μm(cubical,20H μPL).After extensive morphological and physicochemical characterizations,the apparent Young’s modulus of the μPL was quantified under compressive loading returning an average value of~6 kPa,independently of the particle morphology.Then,using a linear two-axis tribometer,the static(μ_(s))and dynamic(μ_(d))friction coefficients of the μPL-enriched simulated synovial fluid were determined in terms of particle configuration and concentration,varying from 0(fluid only)to 6×10^(5) μPL/mL.The particle morphology had a modest influence on friction,possibly because the μPL were fully squeezed between two mating surfaces by a 5.8 N normal load realizing boundary-like lubrication conditions.Differently,friction was observed to depend on the dimensionless parameterW,defined as the ratio between the total volume of the μPL enriching the simulated synovial fluid and the volume of the fluid itself.Both coefficients of friction were documented to grow withWreaching a plateau of μ_(s)~0.4 and μ_(d)~0.15,already at Ω~2×10^(-3).Future investigations will have to systematically analyze the effect of sliding velocity,normal load,and rigidity of the mating surfaces to elucidate in full the tribological behavior of μPL in the context of osteoarthritis. | Agnese FRAGASSI Antonietta GRECO Martina DI FRANCESCO Luca CESERACCIU Aiman ABU AMMAR Israel DVIR Thomas Lee MOORE Haytam KASEM Paolo DECUZZI | 2024 | Friction2024，12，3： | 0 |
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