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| 1 | Emotion processing in Parkinson's disease: a blood oxygenation level-dependent functional magnetic resonance imaging study显示文摘Parkinson's disease is a neurodegenerative disorder caused by loss of dopamine neurons in the substantia nigra pars compacta. Tremor, rigidity, and bradykinesia are the major symptoms of the disease. These motor impairments are often accompanied by affective and emotional dysfunctions which have been largely studied over the last decade. The aim of this study was to investigate emotional processing organization in the brain of patients with Parkinson's disease and to explore whether there are differences between recognition of different types of emotions in Parkinson's disease. We examined 18 patients with Parkinson's disease(8 men, 10 women) with no history of neurological or psychiatric comorbidities. All these patients underwent identical brain blood oxygenation level-dependent functional magnetic resonance imaging for emotion evaluation. Blood oxygenation level-dependent functional magnetic resonance imaging results revealed that the occipito-temporal cortices, insula, orbitofrontal cortex, basal ganglia, and parietal cortex which are involved in emotion processing, were activated during the functional control. Additionally, positive emotions activate larger volumes of the same anatomical entities than neutral and negative emotions. Results also revealed that Parkinson's disease associated with emotional disorders are increasingly recognized as disabling as classic motor symptoms. These findings help clinical physicians to recognize the emotional dysfunction of patients with Parkinson's disease. | Mohammed Benzagmout Sa?d Boujraf Badreeddine Alami Hassane Ali Amadou Halima El Hamdaoui Amine Bennani Mounir Jaafari Ismail Rammouz Mustapha Maaroufi Rabia Magoul Driss Boussaoud | 2019 | Neural Regeneration Research2019，14，4： | 6 |
| 2 | Detection of class 1 integron in Acinetobacter baumannii isolates collected from nine hospitals in Turkey显示文摘Objective:To investigate the antibiotic resistance genes inserted into class I and class 2integrons in Acinetobacler baumannii[A.baumannii)isolates obtained from nine different cities in Turkey.Methods:A collection of 281 A.baumannii clinical isolates were collected from nine diferenl state hospitals in Turkey and were confirmed as A.baumannU by conventional biochemical,API testing and bla_(-OXA-51)specific PCR.The isolates were examined by PCR for existence of class I and2 integron gene cassettes.Results:They were characterized by antimicrobial susceptibility testing and the highest resistance rates were determined for piperacillin(90.03%),ciprofloxacin(87.54%),cefepime and trimethoprim/sulfamethoxazole(81.13%).The lowest resistance rates was for cefotaxime(3.55%).class 1 integrons were detected in 6.4%(18/281)of A.baumannii strains and no class 2 integron was detected.The gene casselles of class 1 inlegrons AacCI-AAC(3)l-aadAI,AacCI-aadA1,AAC(3)-I,AAC(3)-I-AAC(3)-I-aadA1,TEM-1.AAC(3)-I-aadA1-AAC(3)-I-AAC(3)-I,AAC(3)-I-AAC(3)-I-AAC(3)-I-aadA1,AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I,AAC(3)-I-aadA1-AAC(3)-I-aadA1,AAC(3)-I-AAC(3)-I-aadA1-AAC(3)-I-aadA1 were detected in eighteen strains.The aac genes family were most frequently found integrated into the class 1 inlegrons and it was followed by aadA genes and TEM-1 genes.Conclusions:This is an extensive study on the distribulion of class 1 integron among A.baumannii in Turkey.In addition to these,two new alleles were observed.Their percentage rates of similarity to other cassettes are 95%aadA1(TK A18)and 89%,aadA 1(ANKA3). | Aysegül Copur Cicek Azer Ozad Düzgün Aysegül Saral Tuba Kayman Zeynep Cizmeci Pervin Ozlem Balci Tuba Dal Mehmet Firat Ismail Tosun Yasemin Ay Alitntop Ahmet Caliskan Yelda Yazici Cemal Sandalli | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，9： | 3 |
| 3 | Efficacy and Safety Comparison of Liraglutide, Glimepiride, and Placebo, All in Combination With Metformin, in Type 2 Diabetes: The LEAD (Liraglutide Effect and Action in Diabetes)-2 study显示文摘 | Nauck Michael Frid Anders Hermansen Kjeld Shah Nalini S Tankova Tsvetalina Mitha Ismail H Zdravkovic Milan Düring Maria Matthews David R | 2009 | Diabetes Care2009，，： | 2 |
| 4 | A cohort study of people with diabetes and their first foot ulcer : the role of depression on mortality 显示文摘 | Ismail K Winkley K Stahl D | 2007 | Diabetes Care2007，30，： | 1 |
| 5 | Defining incident vertebral deformities in population studies:a comparison of morphometric criteria显示文摘 | Lunt M Ismail AA Felsenberg D | | 0，，10： | 1 |
| 6 | Prediction of flow distributions and pressure changes in multi-layered annular packed beds显示文摘 | Heggs P J Ellis D I Ismail M S | | 0，，04： | 1 |
| 7 | Modeling and optimization IV:Investigation of reaction kinetics and kinetic constants using a program in which artificial neural network (ANN) was integrated显示文摘 | DENIZ B FAHRIYE C D ISMAIL H B | | 0，，： | 1 |
| 8 | Comparative lipid peroxidation,antioxidant defense systems and praline content in roots cultivars differing in salt tolerance显示文摘 | Tijen D Ismail T | 2005 | Environmental and Experimental Botany2005，53，： | 1 |
| 9 | Persistent hyperinsulinaemic hypoglycaemia of infancy: 15 years' experience at the Royal Children's Hospital (RCH), Melbourne 显示文摘 | Ismail D Werther G | 2005 | Pediatr Endocrinol Metab2005，18，11： | 1 |
| 10 | Effects of oleoresin-tocopherol combinations on lipid oxidation, off-odor, and color of irradiated raw and cooked pork patties 显示文摘 | Nam K C Ko K Y Min B R Ismail H Lee E J Cordray J Ahn D U | 2007 | Meat Science2007，，： | 1 |
| 11 | Macrophage microvesicles induce macrophage differentiation and miR 223 transfer 显示文摘 | Ismail N Wang Y Dakhlallah D | 2013 | Blood2013，121，6： | 1 |
| 12 | Characterizing the Saltol quantitative trait locus for salinity tolerance in rice 显示文摘 | Thomson M J Ocampo M Egdane J Rahman M A Sajise A G Adorada D L Tumimbang-Raiz E Blumwald E Seraj Z I Singh R K Gregorio G B Ismail A M | 2010 | Rice2010，3，2： | 1 |
| 13 | Oil palm wood flour filled natural rubber composites: The effects of various bonding agents显示文摘 | Ismail H Jaffri R M Rozman H D | 2001 | International Journal of Polymeric Materials2001，49，： | 1 |
| 14 | The genetic basis of congenital hyperinsulinism显示文摘 | James C Kapoor RR Ismail D | | 0，，05： | 1 |
| 15 | Persistent hyperinsulinaemic hypogly- eaemia of infancy: 15 years' experience at the Royal Chil- dren's Hospital (RCH), Melbourne 显示文摘 | Ismail D Werther G | 2005 | J Pediatr Endoerinol Metab2005，18，11： | 1 |
| 16 | Effect of Silica Fume andExpanded Perlite Addition on the Technical FVoperties ofthe Fly Ash-Lime-Gypsum Mixture 显示文摘 | Ismail D M Baspinar M S | 2007 | Construction andBuilding Materials2007，22，12： | 1 |
| 17 | Modeling andoptimization III:Reaction rate estimation using artificial neural network (ANN) without a kinetic mode显示文摘 | DENIZ B FAHRIVE C D ISMAIL H B | | 0，，： | 1 |
| 18 | Responses of SUB1 rice introgression lines to submergence in the field: and grain quality 显示文摘 | Singh S Mackill D J Ismail A M | 2009 | Field Crop Research2009，113，1： | 1 |
| 19 | The effects of filler loading and vulcanisation system on properties of oil palm wood flournatural rubber composites显示文摘 | Ismail H Jaffri R M Rozman H D | 2003 | Journal of Elastomers and Plastics2003，35，2： | 1 |
| 20 | Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface 显示文摘 | Vaishnava S Behrendt C L Ismail A S et d | 2008 | Proc Natl Acad Sci U S A2008，105，20： | 1 |
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