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		题名	作者	年代	出处	被引量
	1	Glutathione peroxidase activity in cell cultures from different regions of human epididymis显示文摘Aim: To study the secretory activity and androgen regulation of glutathione peroxidase (GPx) in epithelial cell cultures from human epididymis. Methods: Tissue was obtained from patients undergoing therapeutic orchidectomy for prostatic cancer. Epithelial cell cultures were obtained from the caput, corpus and cauda epididymides. Enzymatic activity was measured in conditioned media by colorimetric methods in absence or presence of 1, 10 or 100 nmol·L^-1 testosterone. The effect of 1 μmol·L^-1 flutamide was also evaluated. Results: GPx activity was higher in cultures from corpus and cauda than caput epididymidis. The presence of different concentrations of testosterone increase enzyme activity in cell cultures from all epididymal regions. Addition of flutamide reverses the androgen dependent increase of GPx activity. Conclusion: GPx activity is secreted from human epididymal cells in a region dependent manner and is regulated by androgens.	Enrique Castellon Hernan Rioseco Juan Rojas Michel Royer Eduardo Salas Hoctor Contreras Christian Huidobro	2005	Asian Journal of Andrology2005，7，1：	2

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