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| 1 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 2 | Tuning sol size to optimize organosilica membranes for gas separation显示文摘A series of organosilica sols are prepared by the polymeric sol–gel method using 1,2-bis(triethoxysilyl)ethane(BTESE)as the precursor.Particle size distributions of the BTESE-derived sols are systematically investigated by carefully adjusting the synthesis parameters(i.e.,water ratios,acid ratios and solvent ratios)in the sol process.In certain conditions,increasing the water ratio or the acid ratio tends to cause larger sol sizes and bimodal particle size distributions.However,higher solvent ratios lead to smaller sol sizes and unimodal particle size distributions.The organosilica membranes prepared from the optimized sols show excellent H_2 permeances(up to 4.2×10^(-7)mol·m^(-2)·s^(-1)·Pa^(-1))and gas permselectitivies(H_2/CO_2 is 9.5,H_2/N_2 is 50 and H_2/CH_4 is 68).This study offers significant insights into the relationship between the sol synthesis parameters,sol sizes and membrane performance. | Huating Song Yibin Wei Chenying Wang Shuaifei Zhao Hong Qi | 2018 | Chinese Journal of Chemical Engineering2018，26，1： | 3 |
| 3 | Meta-analysis of genetic polymorphisms and gastric cancer risk: Variability in associations according to race显示文摘 | Marie Loh King Xin Koh Boon Huat Yeo Chun Meng Song Kee Seng Chia Feng Zhu Khay Guan Yeoh Jeffrey Hill Barry Iacopetta Richie Soong | 2009 | European Journal of Cancer2009，，14： | 2 |
| 4 | Force- closure workspace analysis of cable - driven parallel mechnanisms 显示文摘 | Cong Bang Pham Song Huat Yeo Guilin Yang | 2006 | Mechanism and Machine Theory2006，41，1： | 1 |
| 5 | Simu- lataneous Base and Tool Calibration for Self-calibration Modular Parallel Robot 显示文摘 | YANG guilin CHEN I-Ming YEO Song Huat | 2002 | Robotica2002，20，4： | 1 |
| 6 | Workspace generation and planning singularity-free path for parallel manipulators 显示文摘 | Anjan Kumar Dash I-Ming Chen Song Huat Yeo | 2005 | Mechanism and Machine Theory2005，40，2005： | 1 |
| 7 | Aliphatic C–H and oxygenated surface functional groups of diesel in-cylinder soot: Characterizations and impact on soot oxidation behavior显示文摘 | Lin Wang Chonglin Song Jinou Song Gang Lv Huating Pang Wei Zhang | 2013 | Proceedings of the Combustion Institute2013，，2： | 1 |
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