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| 1 | 锂离子动力电池热失控与安全管理研究综述显示文摘锂离子动力电池具有能量密度高、循环寿命长、无记忆效应等优点,被认为是最具前景的一类动力电池。随着整体能量密度的不断提高和制造成本的降低,以热失控为特征的锂离子动力电池安全事故频发,严重威胁着乘客的人身和财产安全。因此,以防止锂离子电池热失控为核心的研究成为近几年电动车辆研究领域的热点,同时,相关领域的发展也需要这样的综述类文章来的引领。从动力电池安全角度出发,对目前锂离子动力电池热失控研究现状进行综述,总结了最新研究成果。较为具体地阐明了热失控触发条件和发生机理,比较全面地总结了提高锂离子动力电池系统安全性的方法,以期促进先进锂离子动力电池系统安全管理方法与策略的开发,进而提高动力电池系统的安全性。填补了该领域缺少中文综述的空白。 | 朱晓庆 王震坡 WANG Hsin 王聪 | 2020 | 机械工程学报2020，56，14： | 74 |
| 2 | Age-stage, two-sex life tables of Bactrocera cucurbitae (Coquillett) (Diptera: Tephritidae) with a discussion on the problem of applying female age-specific life tables to insect populations显示文摘 | Yu-Bing Huang Hsin Chi | 2012 | Insect Science2012，19，2： | 31 |
| 3 | Overcharge-to-thermal-runaway behavior and safety assessment of commercial lithium-ion cells with different cathode materials:A comparison study显示文摘In this paper,overcharge behaviors and thermal runaway(TR)features of large format lithium-ion(Liion)cells with different cathode materials(LiFePO4(LFP),Li[Ni_(1/3)Co_(1/3)Mn_(1/3)]O_(2)(NCM111),Li[Ni_(0.6)Co_(0.2)Mn_(0.2)]O_(2)(NCM622)and Li[Ni_(0.8)Co_(0.1)Mn_(0.1)]O_(2)(NCM811))were investigated.The results showed that,under the same overcharge condition,the TR of LFP Li-ion cell occurred earlier compared with the NCM Li-ion cells,indicating its poor overcharge tolerance and high TR risk.However,when TR occurred,LFP Li-ion cell exhibited lower maximum temperature and mild TR response.All NCM Liion cells caught fire or exploded during TR,while the LFP Li-ion cell only released a large amount of smoke without fire.According to the overcharge behaviors and TR features,a safety assessment score system was proposed to evaluate the safety of the cells.In short,NCM Li-ion cells have better performance in energy density and overcharge tolerance(or low TR risk),while LFP Li-ion cell showed less severe response to overcharging(or less TR hazards).For NCM Li-ion cells,as the ratio of nickel in cathode material increases,the thermal stability of the cathode materials becomes poorer,and the TR hazards increase.Such a comparison study on large format Li-ion cells with different cathode materials can provide deeper insights into the overcharge behaviors and TR features,and provide guidance for engineers to reasonably choose battery materials in automotive applications. | Zhenpo Wang Jing Yuan Xiaoqing Zhu Hsin Wang Lvwei Huang Yituo Wang Shiqi Xu | 2021 | Journal of Energy Chemistry2021，30，4： | 12 |
| 4 | Spectral tomographic imaging with aplanatic metalens显示文摘Tomography is an informative imaging modality that is usually implemented by mechanical scanning,owing to the limited depth-of-field(DOF)in conventional systems.However,recent imaging systems are working towards more compact and stable architectures;therefore,developing nonmotion tomography is highly desirable.Here,we propose a metalens-based spectral imaging system with an aplanatic GaN metalens(NA=0.78),in which large chromatic dispersion is used to access spectral focus tuning and optical zooming in the visible spectrum.After the function of wavelength-switched tomography was confirmed on cascaded samples,this aplanatic metalens is utilized to image microscopic frog egg cells and shows excellent tomographic images with distinct DOF features of the cell membrane and nucleus.Our approach makes good use of the large diffractive dispersion of the metalens and develops a new imaging technique that advances recent informative optical devices. | Chen Chen Wange Song Jia-Wern Chen Jung-Hsi Wang Yu Han Chen Beibei Xu Mu-Ku Chen Hanmeng Li Bin Fang Ji Chen Hsin Yu Kuo Shuming Wang Din Ping Tsai Shining Zhu Tao Li | 2019 | Light(Science & Applications)2019，8，1： | 12 |
| 5 | 半边旗提取物5F对非小细胞肺癌NCI-H460细胞生长的抑制作用显示文摘目的研究半边旗提取物5F对非小细胞肺癌NCI-H460细胞生长的抑制作用。方法MTT法检测5F对NCI-H460细胞的生长抑制作用;用PI-Hoechst荧光双染法和TUNEL法检测细胞凋亡;流式细胞仪检测5F对DNA含量的影响。结果5F抑制NCI-H460细胞的生长,其效果与5F的浓度和作用时间相关,24、48、72h的IC50分别为:21.40、4.52、1.02μg/ml;荧光双染色法显示经5F作用后细胞出现变形,染色质浓缩,产生凋亡小体;细胞被阻滞在G2/M期。结论5F在体外能有效地抑制NCI-H460细胞的生长,其作用可能是通过诱导其凋亡产生的。 | 刘义 吴科锋 李立 George G CHEN Michael KY HSIN Malcolm J UNDERWOOD 梁念慈 | 2009 | 肿瘤防治研究2009，36，1： | 9 |
| 6 | Identification of Maximum Road Friction Coefficient and Optimal Slip Ratio Based on Road Type Recognition显示文摘The identification of maximum road friction coefficient and optimal slip ratio is crucial to vehicle dynamics and control.However,it is always not easy to identify the maximum road friction coefficient with high robustness and good adaptability to various vehicle operating conditions.The existing investigations on robust identification of maximum road friction coefficient are unsatisfactory.In this paper,an identification approach based on road type recognition is proposed for the robust identification of maximum road friction coefficient and optimal slip ratio.The instantaneous road friction coefficient is estimated through the recursive least square with a forgetting factor method based on the single wheel model,and the estimated road friction coefficient and slip ratio are grouped in a set of samples in a small time interval before the current time,which are updated with time progressing.The current road type is recognized by comparing the samples of the estimated road friction coefficient with the standard road friction coefficient of each typical road,and the minimum statistical error is used as the recognition principle to improve identification robustness.Once the road type is recognized,the maximum road friction coefficient and optimal slip ratio are determined.The numerical simulation tests are conducted on two typical road friction conditions(single-friction and joint-friction)by using CarSim software.The test results show that there is little identification error between the identified maximum road friction coefficient and the pre-set value in CarSim.The proposed identification method has good robustness performance to external disturbances and good adaptability to various vehicle operating conditions and road variations,and the identification results can be used for the adjustment of vehicle active safety control strategies. | GUAN Hsin WANG Bo LU Pingping XU Liang | 2014 | Chinese Journal of Mechanical Engineering2014，27，5： | 8 |
| 7 | 亚洲地区饲料原料和配合饲料中霉菌毒素水平的调查显示文摘 | Hsin Yi Chen Rebekah Rawlings 奥特奇 | 2008 | 饲料研究2008，31，9： | 8 |
| 8 | Arsenic trioxide alleviates airway hyperresponsiveness and eosinophilia in a murine model of asthma显示文摘Asthma is one of the most common chronic airway inflammatory diseases.The clinical hallmarks of asthma include elevated serum levels of immunoglobulin E(IgE),eosinophilic inflammation and airway hyper-responsiveness(AHR).Arsenic trioxide(As2O3)is considered a carcinogen;however,it has also been used to treat diseases,such as syphilis,in traditional Chinese and Western medicine.Today,As2O3 is used as one of the standard therapies for acute promyelocytic leukemia(APL).Previous studies have indicated that As2O3 can induce apoptosis in eosinophils.However,the effect of As2O3 on asthma has not been investigated.We used ovalbumin(OVA)-immunized mice as a model for asthma and treated mice with As2O3 at doses of 2.5 and 5 mg/kg.The mice were then monitored for OVA-specific IgE production,airway inflammatory cell infiltration and AHR.We found that administration of As2O3 in OVA-immunized mice abrogated airway eosinophil recruitment by downregulating eotaxin expression but did not alter serum IgE or IL-5 levels in bronchoalveolar lavage fluid(BALF).Furthermore,the development of AHR and cellular infiltration into the airway were reduced by treating mice with As2O3.In vitro data suggested that low concentrations of As2O3 could induce only a small degree of apoptosis in primary pulmonary cells but could significantly inhibit the secretion of eotaxin by these cells.These results indicate that the administration of As2O3 to OVA-immunized mice can suppress lung allergic inflammatory responses.As2O3 might therefore have therapeutic potential in treating allergic airway inflammatory diseases. | Kuan-Hua Chu Chen-Chen Lee Shao-Chi Hsin Bao-Chang Cai Jin-Hong Wang Bor-Luen Chiang | 2010 | Cellular & Molecular Immunology2010，7，5： | 7 |
| 9 | Active steering control strategy for articulated vehicles显示文摘To improve maneuverability and stability of articulated vehicles, we design an active steering controller, including tractor and trailer controllers, based on linear quadratic regulator(LQR) theory. First, a three-degree-of-freedom(3-DOF) model of the tractor-trailer with steered trailer axles is built. The simulated annealing particle swarm optimization(SAPSO) algorithm is applied to identify the key parameters of the model under specified vehicle speed and steering wheel angle. Thus, the key parameters of the simplified model can be obtained according to the vehicle conditions using an online look-up table and interpolation. Simulation results show that vehicle parameter outputs of the simplified model and Truck Sim agree well, thus providing the ideal reference yaw rate for the controller. Then the active steering controller of the tractor and trailer based on LQR is designed to follow the desired yaw rate and minimize their side-slip angle of the center of gravity(CG) at the same time. Finally, simulation tests at both low speed and high speed are conducted based on the Truck Sim-Simulink program. The results show significant effects on the active steering controller on improving maneuverability at low speed and lateral stability at high speed for the articulated vehicle. The control strategy is applicable for steering not only along gentle curves but also along sharp curves. | Kyong-il KIM Hsin GUAN Bo WANG Rui GUO Fan LIANG | 2016 | Frontiers of Information Technology & Electronic Engineering2016，17，6： | 5 |
| 10 | Sedation-associated hiccups in adults undergoing gastrointestinal endoscopy and colonoscopy显示文摘AIM:To investigate whether the incidence of hiccups in patients undergoing esophagogastroduodenoscopy (EGD) or same-day bidirectional endoscopy (EGD and colonoscopy;BDE) with sedation is different from those without sedation in terms of quantity,duration and typical onset time.METHODS:Consecutive patients scheduled for elective EGD or same-day BDE at the gastrointestinal endoscopy unit or the health examination center were allocated to two groups:EGD without sedation (Group A) and BDE with sedation (Group B).The use of sedation was based on the patients' request.Anesthesiologists participated in this study by administrating sedative drugs as usual.A single experienced gastroenterologist performed both the EGD and the colonoscopic examinations for all the patients.The incidence,duration and onset time of hiccups were measured in both groups.In addition,the association between clinical variables and hiccups were analyzed.RESULTS:A total of 435 patients were enrolled in the study.The incidences of hiccups in the patients with and without sedation were significantly different (20.5% and 5.1%,respectively).The use of sedation for patients undergoing endoscopy was still significantly associated with an increased risk of hiccups (adjusted odds ratio:8.79,P < 0.001) after adjustment.The incidence of hiccups in males under sedation was high (67.4%).The sedated patients who received 2 mg midazolam developed hiccups more frequently compared to those receiving 1 mg midazolam (P = 0.0028).The patients with the diagnosis of gastroesophageal reflux disease (GERD) were prone to develop hiccups (P = 0.018).CONCLUSION:Male patients undergoing EGD or BDE with sedation are significantly more likely to suffer from hiccups compared to those without sedation.Midazolam was significantly associated with an increased risk of hiccups.Furthermore,patients with GERD are prone to develop hiccups. | Chien Cheng Liu Cheng Yuan Lu Chih Fang Changchien Ping Hsin Liu Daw Shyong Perng | 2012 | World Journal of Gastroenterology2012，18，27： | 4 |
| 11 | Bariatric surgery in old age:a comparative study of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in an Asia centre of excellence显示文摘Bariatric surgery has been proved to be the safest and efficient procedure in treating morbid obese patients,but data is still lacking in the elderly population.The aim of our study was to compare the safety and efficacy of laparoscopic Roux-en-Y gastric bypass(LRYGB) and sleeve gastrectomy(LSG) in patients aged more than 55 years.We performed2 a retrospective review of a prospectively collected database.All patients with body mass index(BMI) §32 kg/mand aged more than 55 years undergoing LRYGB or LSG in BMI Surgery Centre,E-Da Hospital between January 2008 and December 2011 with at least one year of follow up were included for the analysis.Demography,peri-operative data,weight loss and surgical complications were all recorded and analyzed.Mean age and BMI of these 68 patients22(22 males and 46 female) were 58.8 years(55-79 years) and 39.5 kg/m(32.00-60.40 kg/m).LRYGB was performed in 44 patients and LSG in 24 patients.The two groups were comparable in their preoperative BMI,American Society of Anaesthesia(ASA) score and gender distribution.LSG patients were significantly older than patients receiving LRYGB.The proportion of type 2 diabetes preoperatively was significantly higher in LRYGB patients as compared to LSG patients(88.63% vs.50%; P,0.01).The prevalence of other co-morbidities was similar and comparable2 between the groups.Mean BMI in the LRYGB and LSG groups at the end of 1 year were 28.8 kg/mand228.2 kg/m,respectively,and there was no statistically significant difference in mean percentage of excess weight loss(%EWL) at 1 year.The percentage of resolution of diabetes was significantly higher in LRYGB(69.2%) as compared to LSG(33.3%).On the other hand,there was no statistical difference in the percentage of resolution of hypertension,hyperlipidemia and fatty liver hepatitis.The overall morbidity and re-operation rate was higher in LRYGB patients.In morbidly elderly patients,both surgeries achieved good weight loss and resolution of comorbidities.LRYGB is superior to LSG in terms of diabetes remission but carries higher complication rates even at high volume centres. | Chih-Kun Huang Amit Garg Hsin-Chih Kuao Po-Chih Chang Ming-Che Hsin | 2015 | The Journal of Biomedical Research2015，29，2： | 4 |
| 12 | 半边旗活性物质5F对非小细胞肺癌NCI-H460细胞IκKβ、IκB、p65及p50 mRNA表达的影响显示文摘目的从NF-κB信号通路着手探讨半边旗活性物质5F诱导非小细胞肺癌NCI-H460细胞凋亡发生的机制。方法MTT法检测5F对NCI-H460细胞的生长抑制作用;用半定量RT-PCR方法检测NCI-H460细胞IκKβ、IκB、p65及p50mRNA表达水平的变化。结果5F抑制NCI-H460细胞的生长,其效果与5F的质量浓度和作用时间相关,24、48、72h的IC50分别为:21.40、4.52、1.02μg/mL;100μg/mL5F作用NCI-H460细胞6h后能引起IκKβ和IκBmRNA表达水平显著降低(P<0.05);p65和p50mRNA水平在作用3h就发生明显减少(P<0.05)。结论5F诱导NCI-H460细胞凋亡的机制可能是通过抑制核因子-κB(NF-κB)信号通路来实现的。 | 刘义 CHEN George G 吕应年 HSIN Michael K Y UNDERWOOD Malcolm J 梁念慈 | 2010 | 中草药2010，41，3： | 3 |
| 13 | Liver stiffness measurement as an alternative to fibrotic stage in risk assessment of hepatocellular carcinoma incidence for chronic hepatitis C patients显示文摘 | Hsin‐Ming Wang Chao‐Hung Hung Sheng‐Nan Lu Chien‐Hung Chen Chuan‐Mo Lee Tsung‐Hui Hu Jing‐Houng Wang | 2013 | Liver Int2013，，5： | 3 |
| 14 | The Beneficial Effect of Regular Endurance Exercise Training on Blood Pressure and Quality of Life in Patients with Hypertension显示文摘 | Jen‐Chen Tsai Hung‐Yu Yang Wei‐Hsin Wang Ming‐Hsiung Hsieh Pei‐Ti Chen Ching‐Chiu Kao Pai‐Feng Kao Chia‐Hui Wang Paul Chan | 2004 | Clinical and Experimental Hypertension2004，，3： | 2 |
| 15 | MicroRNA-18a Prevents Estrogen Receptor-α Expression, Promoting Proliferation of Hepatocellular Carcinoma Cells显示文摘 | Wan–Hsin Liu Shiou–Hwei Yeh Cho–Chun Lu Sung–Liang Yu Hsuan–Yu Chen Chien–Yu Lin Ding–Shinn Chen Pei–Jer Chen | 2009 | Gastroenterology2009，，2： | 2 |
| 16 | Impact of rifaximin use for hepatic encephalopathy on the risk of early post‐transplant infections in liver transplant recipients显示文摘 | Hsin‐Yun Sun Marilyn Wagener Thomas V. Cacciarelli Nina Singh | 2012 | Clin Transplant2012，，6： | 2 |
| 17 | Chromatin-binding in vivo of the erythroid kruppel-like factor,EKLF,in the murine globin loci显示文摘EKLF 是一 erythroid 特定,锌为在在权威的系的 erythroid 房间的基因的哺乳动物的贝它滴的激活的包含手指的抄写因素必需品。我们准备了对西方的弄污和免疫降水(IP ) 质量合适的 polyclonal 反老鼠 EKLF 抗体,并且使用了它在老鼠 erythroid 开发期间定义 EKLF 蛋白质的表示模式。我们也为 chromatin-immunoprecipitation (薄片) 使用了这抗体试金。EKLF 被发现以一种 DMSO 可诱导的方式在老鼠 erythroleukemia 房间(MEL ) 在老鼠 beta-major-globin 倡导者和 beta-LCR 的 HS2 地点在 vivo 绑。象三另外的蛋白质一样的 EKLF 的 导致DMSO 的绑定,也就是 RNA 聚合酶 II ,乙酰 ated 嘘一 H3 ,和 methylated 嘘一 H3 ,没在 CB3 被废除,但是显著地降低了,一根 导出MEL 的房间线与 p45/NF-E2 空表示,在 loci 为哺乳动物的滴的激活需要的一个 充实erythroid 的因素。有趣地,在 vivo 的 EKLF 的绑定也在地点在鼠标象 alpha 一样滴被检测,在成年高山哈在倡导者和它的远在上游的规章的元素 alpha-MRE (HS26 ) 的滴。这研究提供直接证据为在在在基因的像贝它的滴聚类的老鼠的主要规章的元素的 vivo EKLF 有约束力数据也在基因规定在哺乳动物的滴关于 EKLF 染色质相互作用的角色有有趣的含意。 | Yu-Chiau Shyu Shau-Ching Wen Tung-Liang Lee Xin Chen Chia-Tse Hsu Hsin Chen Ruei-Lin Chen Jau-Lang Hwang Che-Kun James Shen | 2006 | Cell Research2006，16，4： | 2 |
| 18 | Novel Evaluation Method of Vehicle Suspension Performance Based on Concept of Wheel Turn Center显示文摘The current research of suspension performance evaluation is mixed in the evaluation of vehicle handling and ride comfort. However, it is lack of a direct and independent evaluation method for suspension performance. In this paper, a novel wheel turn center method is proposed to evaluate the suspension performance. This method is based on the concept and application of wheel turn center(WTC) and sprung mass turn center(SPTC). The vehicle body and each wheel are regarded to be independent rigid bodies and have their own turn centers which reflect respective steering motions and responses. Since the suspension is the link between vehicle body and wheels, the consistence between the sprung mass turn center and the wheel turn center reflects the effect and performance of the suspension system. Firstly, the concept and appropriate calculation method of WTC and SPTC are developed. Then the degree of inconsistence between WTC and SPTC and the time that they achieve consistence, when the vehicle experiences from transient steering to steady steering state, are proposed to evaluate suspension performance. The suspension evaluation tests are conducted under different vehicle velocities and lateral accelerations by using Car Sim software. The simulation results show that the inconsistence of steering motion between vehicle body and wheels are mainly at high speeds and low lateral accelerations. Finally, based on the proposed evaluation indexes, the influences of different suspension characteristic parameters on suspension performance and their matches to improve steering coordination are discussed. The proposed wheel turn center method provides a guidance and potential application for suspension evaluation and optimization. | WANG Bo GUAN Hsin LU Pingping ZHAN Jun | 2015 | Chinese Journal of Mechanical Engineering2015，28，5： | 2 |
| 19 | Effects of Maternal Screening and Universal Immunization to Prevent Mother-to-Infant Transmission of HBV显示文摘 | Huey–Ling Chen Lung–Huang Lin Fu–Chang Hu Jian–Te Lee Wen–Terng Lin Yao–Jung Yang Fu–Chen Huang Shu–Fen Wu Solomon Chih–Cheng Chen Wan–Hsin Wen Chia–Hsiang Chu Yen–Hsuan Ni Hong–Yuan Hsu Pei–Lin Tsai Cheng–Lun Chiang Ming–Kwang Shyu Ping–Ing Lee Feng–Yee | 2012 | Gastroenterology2012，，4： | 2 |
| 20 | 高速连铸用新型浸入式水口显示文摘连铸机结晶器内钢液的流动状态严重影响连铸坯的质量,尤其在弯月面处,钢液与结晶器保护渣直接接触,结晶器内弯月面不稳定引起的卷渣,是导致产品产生缺陷的主要原因之一,如冷轧薄板的线状缺陷和厚板的表面缺陷。在结晶器润滑不均匀时,还会增加漏钢危险。弯月面液面波动主要是由于浸入式水口吐出孔钢液剧烈的湍流和瞬态行为引起的。最近,在一台连铸机上浇注不同钢种已成为全世界钢铁生产商努力的一个主要方向。为了满足所有钢种的质量要求,对每个钢种都要求一定的浇注速度。对常规的浸入式水口而言,确保结晶器内有利的流动条件是一个难题。因此,比以往更需要一种新型浸入式水口,通过保持最佳的结晶器内钢液流动状态,以各种浇注速度浇注出多规格铸坯。介绍了测试新型浸入式水口流动性能的数值模型和物理模型的试验。采用URANS方法瞬态CFD模拟表明,新型浸入式水口流出的钢液瞬态行为稳定,因而弯月面以下钢液流速较慢,其效果还通过水模拟得到了验证。现场试验是在中国台湾的中钢公司进行的,试验结果表明,通过优化结晶器内钢液的流动行为,结晶器液面波动明显减小,从而提高了产品质量。 | Shung Sheng Kao Hsin Chin Kua Oliver Wiens Wolfgang Mo?ner Markus Reifferscheid Nobert Vogl Gernot Hackl Gerald Nitzl 潘秀兰 | 2014 | 世界钢铁2014，，1： | 2 |
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