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| 1 | Solvothermal-Assisted Exfoliation Process to Produce Graphene with High Yield and High Quality显示文摘Monolayer and bilayer graphene sheets have been produced by a solvothermal-assisted exfoliation process in a highly polar organic solvent,acetonitrile,using expanded graphite(EG)as the starting material.It is proposed that the dipole-induced dipole interactions between graphene and acetonitrile facilitate the exfoliation and dispersion of graphene.The facile and effective solvothermal-assisted exfoliation process raises the low yield of graphene reported in previous syntheses to 10 wt%12 wt%.By means of centrifugation at 2000 rpm for 90 min,monolayer and bilayer graphene were separated effectively without the need to add a stabilizer or modifi er.Electron diffraction and Raman spectroscopy indicate that the resulting graphene sheets are high quality products without any signifi cant structural defects. | Wen Qian Rui Hao Yanglong Hou Yuan Tian Chengmin Shen Hongjun Gao Xuelei Liang | 2009 | Nano Research2009，2，9： | 28 |
| 2 | Protective effects of Yindanxinnaotong capsule in a rat model of myocardial ischemia/reperfusion injury显示文摘OBJECTIVE: To investigate the effects of Yindanxinnaotong capsule(YDXNTC) and main components compatibility and ratios on myocardium against ischemia/reperfusion injury and the effect's underlying mechanism.METHODS: Myocardial ischemia/reperfusion injury(MIRI) was induced by ischemia for 30 min and reperfusion for 30 min. Electrocardiogram data and coronary flow were recorded, and superoxide dismutase(SOD), malondialdehyde(MDA), lactate dehydrogenase, creatine kinase-MB, cardiac troponin T and I(cT nT, cT n I) and interleukin-1β, interleukin-8,interleukin-18(IL-1β, IL-8, IL-18) in myocardium were measured. Hypoxia/reoxygenation and hydrogen peroxide(H2O2) injury were induced by hypoxia for 3 h/reoxygenation for 2 h, and 100 μM H2O2 for 1 h, respectively, in vitro rat myocardial cells(H9c2). Cell viability, SOD, MDA, cT nT and inflamma-tory factors(IL-1β, IL-8 and IL-18) were determined,and Toll-like receptor 4(TLR-4) expression was measured by western blotting.RESULTS: In the isolated heart experiment, elevated heart function, coronary flow and SOD levels,and decreased MDA levels and inflammatory factors were noted in the YDXNTC, main components and main components compatibility groups. Ventricular tachycardia/ventricular fibrillation occurrence decreased in the ginkgo biloba extract(GBE),and GBE and salvia miltiorrhiza ethanol extract compatibility(SM-E, GSEC) groups. Lactic dehydrogenase levels decreased in the YDXNTC and aqueous extract of salvia miltiorrhiza(SM-H) groups. Creatine kinase-MB decreased with GBE, SM-E, SM-H and GSEC treatment, and cT n I and cT nT levels decreased with GSEC. In the in vitro cell study,YDXNTC and main components ratios improved cell viability and SOD levels, and suppressed MDA,cT nT and inflammatory factors. TLR-4 expression was down-regulated.CONCLUSION: YDXNTC and main components compatibility showed protective effects on MIRI in this rat model and in vitro study. Regulating the Toll-like receptor signaling pathway may affect the mechanism. | Wandan Wang Lan Wang Hongjun Yang Jianlu Wang Xiaojie Yin Haiyu Xu Long Cheng Rixin Liang | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 22 |
| 3 | Exploratory Precipitation in North-Central China during the Past Four Centuries显示文摘Two robust precipitation reconstructions were conducted by combining tree-ring chronologies, dryness/wetness indices from historical documents, and climate data from the global grid. It was found that the recurrent drought history of a region can help us understand the variability of precipitation. Several dry/wet periods during the past four centuries and potential cycles of precipitation variation were determined. Furthermore, the reconstructions are not only consistent well with each other in North-central China, but also in good agreement with variations of precipitation in northeastern Mongolia, the Longxi area in Gangsu Province and the Dulan area of Qinghai Province, and the snow accumulation of the Guliya glacier. These synchronous variations indicate that it is valuable to study various climate records, find common information and determine the driving force of climate change. | YI Liang YU Hongjun XUXingyong YAO Jing SU Qiao GE Junyi | 2010 | Acta Geologica Sinica(English Edition)2010，84，1： | 11 |
| 4 | Paleoenvironmental changes during the late Quaternary as inferred from foraminifera assemblages in the Laizhou Bay显示文摘Controlled by climate changes, there were three large-scale transgressions and regressions around the Bohai Sea during the late Quaternary, which were accepted by most geologists. However, a big controversy still exists about the time when the transgressions occurred separately. In order to find out the process of the paleoenvironmental changes around the Bohai Sea in the late Quaternary, the foraminifera assemblages from a new borehole Lz908 in the southern coast of the Laizhou Bay were studied, and then the transgressive strata were indentified. Combined with accelerator mass spectrometry radiocarbon 14C(AMS14C) and optically stimulated luminescence(OSL) ages, the occurrence time of these transgressions were re-determined. The result showed that three major large-scale transgressions occurred separately at the beginning of marine isotopic stage 7(MIS7), the last interglacial period(MIS5) and the Holocene. In addition, a small-scale transgression occurred in the mid-MIS6, and the corresponding transgressive stratum was deposited. The transgressive deposition of MIS3 was also discovered in this study. However, the characteristics of the foraminifera indicated the environment during this period was colder than that in the MIS5. By comparison with the global sea-level changes, the paleoenvironmental changes around the Bohai Sea in the late Quaternary can be consistent with the global climate changes. | YAO Jing YU Hongjun XU Xingyong YI Liang CHEN Guangquan SU Qiao | 2014 | Acta Oceanologica Sinica2014，33，10： | 6 |
| 5 | Effects of heat treatment on the microstructure and mechanical properties of ZA84 magnesium alloy显示文摘The effects of heat treatment on the microstructure and mechanical properties of ZA84 (Mg-8Zn-4Al-0.25Mn) alloy were investigated. The results indicate that the as-cast microstructure of the alloy is mainly composed of α-Mg matrix and two different morphologies of precipitates (continuous and quasi-continuous Mg32(Al,Zn)49 phases and isolated Mg5Al2Zn2 phases). After solid solution treatment at 345°C, the Mg32(Al,Zn)49 phases change from continuous and quasi-continuous net to disconnected acute angle shape, and parts of second phases sphericize. The optimum heat treatment condition for the alloy is solution treatment at 345°C for 48 h and water quenching, then aging treatment at 200°C for 12 h and atmosphere cooling. Under the optimum condition, the ulti-mate tensile strength and yield strength of the alloy can be improved, but the elongation is not effected much by heat treatment. | Mingbo Yang Liang Bai Fusheng Pan Hongjun Hu | 2008 | Journal of University of Science and Technology Beijing2008，15，6： | 5 |
| 6 | Immunodiagnostic efficacy of detection of Schistosoma japonicum human infections in China:a meta analysis显示文摘Objective:To assess the diagnostic efficacy of the currently most widely used indirect hemagglutination assay(IHA) and enzyme-linked immunosorbent assay(ELISA) for detection of Schistosoma japonicum human infections.Methods:A comprehensive search was undertaken from China National Knowledge Infrastructure,Wanfang Database.VIP Database,PubMed. Cochrane Library,Science Citation Index Expanded.Proquest,and the inclusion and exclusion criteria were strictly settled.The funnel plot was used to assess the publication bias.Cochran’s Q test was employed to measure the homogeneity between studies,a summary receiver operating characteristic(SROC) curve was used to compare the diagnostic accuracy between the IHA and ELISA qualitatively by means of the Weighted Least Square method,the Ordinary Least Square method and the Robust regression method,and the diagnostic odds ratio(DOR) was drawn to compare the accuracy quantitatively.Results:Out of 785 publications,19 papers were eventually selected for analysis.Literature finality assessment indicated that minor publication bias existed in studies pertaining IHA test,but no bias was found in literatures regarding ELISA test.The heterogeneity test showed a heterogeneity between studies was present(χ~2 =466.07 and 34.67. both P values<0.0001).The areas under the SROC curves of IHA were all higher than that of ELISA test using the three methods(Weighted Least Square method:0.766 vs.0.695.Ordinary Least Square method:0.826 vs.0.741.Robust regression:0.815 vs.0.715).The TPR* values for IHA and EUSA were 0.710.0.759.0.749.and 0.650.0.686 and 0.666.respectively,and OR values were 5.997.9.937.8.893.and 3.432.4.784 and 3.959.respectively.The DOR of IHA was 9.41(95% CI:4.88-18.18).and 4.78(95%CI:3.21-7.13) for ELISA.Conclusions:All above results revealed that the diagnostic performance of IHA is better than that of ELISA.However,taking into account their unsatisfactory diagnostic value in areas with low infection intensity,a search for a better diagnostic test that can be applied in field situations in China should be given high priority. | Wei Wang Youzi Li Hongjun Li Yuntian Xing Guoli Qu Jianrong Dai Yousheng Liang | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，1： | 4 |
| 7 | Laser-induced oxidation assisted micro milling of high aspect ratio microgroove on WC-Co cemented carbide显示文摘Severe tool wear and poor surface quality are the main problems during micro machining of cemented carbide.In this work,an innovative hybrid process of laser-induced oxidation assisted micro milling(LOMM)was proposed to solve the problems.A nanosecond laser was utilized to induce oxidation of the WC-20%Co material,producing loose oxide which was easy to remove.The micro machinability of the material was improved by laser-induced oxidation.The oxidation mechanisms of cemented carbide were studied.A microgroove with a depth of 2.5 mm and aspect ratio of 5 was fabricated successfully.The milling force,surface quality and tool wear mechanisms were investigated.For comparison,a microgroove was also fabricated with conventional micro milling(COMM)using identical milling parameters.Results revealed that in LOMM the milling force and tool wear rate were extremely low during removing the oxide.The machined surface quality and dimensional accuracy achieved by LOMM were superior to those obtained by COMM.The surface roughness Saof the microgroove bottom reached 88 nm in LOMM,while the cross-sectional geometry of the microgroove was a trapezoid.Perpendicularity of the microgroove sidewall machined by LOMM was better than that by COMM.The tool wear forms in LOMM were coating spalling and slight tool nose breakage.Compared with COMM,the tool life in LOMM was prolonged significantly.It indicates that the proposed hybrid process is an effective and efficient way to fabricate high aspect ratio micro-features with high dimensional accuracy. | Guolong ZHAO Hongjun XIA Yang ZHANG Liang LI Ning HE Hans Nφrgaard HANSEN | 2021 | Chinese Journal of Aeronautics2021，34，4： | 3 |
| 8 | Diagnostic Value of Dynamics Serum sCD163, sTREM-1, PCT, and CRP in Differentiating Sepsis, Severity Assessment, and Prognostic Prediction显示文摘 | Longxiang Su Lin Feng Qing Song Hongjun Kang Xingang Zhang Zhixin Liang Yanhong Jia Dan Feng Changting Liu Lixin Xie Celeste C. Finnerty | 2013 | Mediators of Inflammation2013，，： | 2 |
| 9 | Correlation of DNA methylation patterns to the phenotypic features of Tibetan elite alpinists in extreme hypoxia显示文摘High altitude is an extreme environment that imposes hypoxic pressure on physiological processes,and natives living at high altitudes are more adaptive in certain physiological processes.So far,epigenetic modifications under extreme changes in hypoxic pressures are relatively less understood.Here,we recruit 32 Tibetan elite alpinists(TEAs),who have successfully mounted Everest(8848 m)at least five times.Blood samples and physiological phenotypes of TEAs and 32 matched non-alpinist Tibetan volunteers(non-TEAs)are collected for analysis.Genome-wide DNA methylation analysis identifies 23,202 differentially methylated CpGs(P_(adj)<0.05,|β|>0.1)between the two groups.Some differentially methylated CpGs are in hypoxia-related genes such as PPP1R13L,MAP3K7CL,SEPTI-9,and CUL2.In addition,Gene ontology enrichment analysis reveals several inflammation-related pathways.Phenotypic analysis indicates that 12 phenotypes are significantly different between the two groups.In particular,TEAs exhibit higher blood oxygen saturation levels and lower neutrophil count,platelet count,and heart rate.For DNA methylation association analysis,we find that two CpGs(cg16687447,cg06947206)upstream of PTEN were associated with platelet count.In conclusion,extreme hypoxia exposure leads to epigenetic modifications and phenotypic alterations of TEA,providing us clues for exploring the molecular mechanism underlying changes under extreme hypoxia conditions. | Zhuoma Basang Shixuan Zhang La Yang Deji Quzong Yi Li Yanyun Ma Meng Hao WeiLin Pu Xiaoyu Liu Hongjun Xie Meng Liang Jiucun Wang Qiangba Danzeng | 2021 | Journal of Genetics and Genomics2021，48，10： | 2 |
| 10 | Porous carbon and carbon/metal oxide microfibers with well-controlled pore structure and interface显示文摘 | Shi Qihui Liang Hongjun Feng Dan | 2008 | J Am Chem Soc2008，130，15： | 1 |
| 11 | Factors affecting THMs, HAAs and HNMs formation of Jin Lan Reservoir water exposed to chlorine and monochloramine显示文摘 | Huachang Hong Yujing Xiong Mengyong Ruan Fanglei Liao Hongjun Lin Yan Liang | 2013 | Science of the Total Environment2013，，： | 1 |
| 12 | Plasma surface modification of poly (m-aramide) fabric for adhesion improvement to fluorosilicone rubber 显示文摘 | Zheng Zhang Hongjun Liang | 2001 | Journal of Adhesion Science Technology2001，15，7： | 1 |
| 13 | Comprehensive Investigation of Submarine Slide Zones and Mass Movements at the Northern Continental Slope of South China Sea显示文摘Multi-beam bathymetry and seismic sequence surveys in the northern slope of the South China Sea reveal detailed geomorphology and seismic stratigraphy characteristics of canyons, gullies, and mass movements. Modern canyons and gullies are roughly elongated NNW–SSW with U-shaped cross sections at water depths of 400–1000 m. Mass movements include slide complexes, slide scars, and debris/turbidity flows. Slide complexes and slide scars are oriented in the NE–SW direction and cover an area of about 1790 and 926 km^2, respectively. The debris/turbidity flows developed along the lower slope. A detailed facies analysis suggests that four seismic facies exist, and the late Cenozoic stratigraphy above the acoustic basement can be roughly subdivided into three sequences separated by regional unconformities in the study area. The occurrence of gas hydrates is marked by seismic velocity anomalies, bottom-simulating reflectors, gas chimneys, and pockmarks in the study area. Seismic observations suggest that modern canyons and mass movements formed around the transition between the last glacial period and the current interglacial period. The possible existence and dissociation of gas hydrates and the regional tectonic setting may trigger instability and mass movements on the seafloor. Canyons may be the final result of gas hydrate dissociation. Our study aims to contribute new information that is applicable to engineering construction required for deep-water petroleum exploration and gas hydrate surveys along any marginal sea. | CHEN Hongjun LIANG Jin GONG Yuehua | 2018 | Journal of Ocean University of China2018，17，1： | 1 |
| 14 | Real-time yaw rate prediction based on nonlinear model and feedback compensation for vehicle dynamic control显示文摘 | ZHU Hongjun LI Liang JIN M | | 0，，10： | 1 |
| 15 | Real-time yaw rate prediction based on nonlinear model and feedback compensation for vehicle dynamic control显示文摘 | ZHU Hongjun LI Liang JIN M | | 0，，： | 1 |
| 16 | 显示文摘 | Liang Hongjun Angelini T E Ho J | 2003 | J Am Chem Soc2003，125，11： | 1 |
| 17 | Molecular imprinting of biomineralized CdS nanostructures:crystallographic control using self-assembled DNA-membrane templates显示文摘 | Hongjun Liang Thomas E Angelini James Ho | 2003 | J Am Chem Soc2003，125，11： | 1 |
| 18 | Influence of dynamic unbalance of wheelsets on the dynamic performance of high-speed cars显示文摘With further increasing in running speed of newer high-speed EMUs(electric multiple units),higher demand for wheelset dynamic balance is required.In order to study the influence of the dynamic unbalance of wheelset on the stability,ride quality,and curving performance for a high-speed car,a detailed dynamic model of a high-speed EMU car is established using the software SIMPACK.The analysis results indicate that the dynamic unbalance of the wheelset significantly influences the dynamic performance of the high-speed car.The increase in dynamic unbalance of the wheelset will decrease the hunting critical speed,worsen the vertical ride quality,and increase the wheelset lateral force,derailment coefficient,and wheel unloading ratio.Therefore,in order to improve the stability,ride quality,and running safety of high-speed car,the values of dynamic unbalance of wheelset should be strictly controlled in manufacturing,and periodically monitored in operation. | Yong WANG Hongjun KANG Xiaowen SONG Yaru LIANG | 2011 | Journal of Modern Transportation2011，19，3： | 1 |
| 19 | Self-as-sembly of disk-like multiring ZnO-SnO2colloidal nanoparticles显示文摘 | Ji Hongjun Liu Xiaoheng Wang Xin Liang Shiming | 2011 | Journal of Colloid and Interface Science2011，54，： | 1 |
| 20 | Identifying key bird species and geographical hotspots of avian influenza A(H7N9)virus in China显示文摘Background:In China since the first human infection of avian influenza A(H7N9)virus was identified in 2013,it has caused serious public health concerns due to its wide spread and high mortality rate.Evidence shows that bird migration plays an essential role in global spread of avian influenza viruses.Accordingly,in this paper,we aim to identify key bird species and geographical hotspots that are relevant to the transmission of avian influenza A(H7N9)virus in China.Methods:We first conducted phylogenetic analysis on 626 viral sequences of avian influenza A(H7N9)virus isolated in chicken,which were collected from the Global Initiative on Sharing All Influenza Data(GISAID),to reveal geographical spread and molecular evolution of the virus in China.Then,we adopted the cross correlation function(CCF)to explore the relationship between the identified influenza A(H7N9)cases and the spatiotemporal distribution of migratory birds.Here,the spatiotemporal distribution of bird species was generated based on bird observation data collected from China Bird Reports,which consists of 157272 observation records about 1145 bird species.Finally,we employed a kernel density estimator to identify geographical hotspots of bird habitat/stopover that are relevant to the influenza A(H7N9)infections.Results:Phylogenetic analysis reveals the evolutionary and geographical patterns of influenza A(H7N9)infections,where cases in the same or nearby municipality/provinces are clustered together with small evolutionary differences.Moreover,three epidemic waves in chicken along the East Asian-Australasian flyway in China are distinguished from the phylogenetic tree.The CCF analysis identifies possible migratory bird species that are relevant to the influenza A(H7N9)infections in Shanghai,Jiangsu,Zhejiang,Fujian,Jiangxi,and Guangdong in China,where the six municipality/provinces account for 91.2%of the total number of isolated H7N9 cases in chicken in GISAID.Based on the spatial distribution of identified bird species,geographical hotspots are further estimated and illustrated within these typical municipality/provinces.Conclusions:In this paper,we have identified key bird species and geographical hotspots that are relevant to the spread of influenza A(H7N9)virus.The results and findings could provide sentinel signal and evidence for active surveillance,as well as strategic control of influenza A(H7N9)transmission in China. | Benyun Shi Xiao-Ming Zhan Jin-Xin Zheng Hongjun Qiu Dan Liang Yan-Ming Ye Guo-Jing Yang Yang Liu Jiming Liu | 2018 | Infectious Diseases of Poverty2018，7，1： | 1 |
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