|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Development and validation of a questionnaire-based risk scoring system to identify individuals at high risk for gastric cancer in Chinese populations显示文摘Objective:This study aimed to develop and validate a risk scoring system to identify high-risk individuals carrying malignant lesions in stomach for tailored gastric cancer screening.Methods:A gastric cancer risk scoring system(GC-RSS)was developed based on questionnaire-based predictors for gastric cancer derived from systematic literature review.To assess the capability of this system for discrimination,risk scores for 8,214 and 7,235 outpatient subjects accepting endoscopic examination in two endoscopy centers,and 32,630 participants in a community-based cohort in China were calculated to plot receiver operating characteristic curves and generate area under the curve(AUC).To evaluate the performance of GC-RSS,the screening proportion,sensitivity and detection rate ratio compared to universal screening were used under different risk score cutoff values.Results:GC-RSS comprised nine predictors including advanced age,male gender,low body mass index(<18.5 kg/m^(2)),family history of gastric cancer,cigarette smoking,consumption of alcohol,preference for salty food,irregularity of meals and consumption of preserved food.This tool performed well in determining the risk of malignant gastric lesions with AUCs of 0.763,0.706 and 0.696 in three validation sets.When subjects with risk scores≥5 were evaluated with endoscopy,nearly 50%of these endoscopies could be saved with a detection rate of over 1.5 times achieved.When the cutoff was set at 8,only about 10%of subjects with the highest risk would be offered endoscopy,and detection rates for gastric cancer could be increased 2-4 fold compared to universal screening.Conclusions:An effective questionnaire-based GC-RSS was developed and validated.This tool may play an important role in establishing a tailored screening strategy for gastric cancer in China. | Ren Zhou Hongchen Zheng Mengfei Liu Zhen Liu Chuanhai Guo Hongrui Tian Fangfang Liu Ying Liu Yaqi Pan Huanyu Chen Zhe Hu Hong Cai Zhonghu He Yang Ke | 2021 | Chinese Journal of Cancer Research2021，33，6： | 3 |
| 2 | Mechanical Behavior and Microstructure Evolution of a Rolled Magnesium Alloy AZ31B Under Low Stress Triaxiality显示文摘Plastic deformation up to final rupture failure of a rolled magnesium(Mg) alloy Mg–3.0Al–1.0Zn–0.34Mn(AZ31B) under low stress triaxiality was investigated.Local strain evolution was quantified by the digital image correlation(DIC) technique analysis with tensile,combined tensile-shear,and shear specimens,corresponding to the stress triaxiality of 1/3,1/6 and 0,respectively.Stress–strain curves show that the yield stress reduces with the decrease in the stress triaxiality,and obviously exhibits different strain hardening response.Electron backscatter diffraction(EBSD) observations reveal that the twinning behavior depends on stress triaxiality.Before fracture,double twinning is the dominant mechanism at the stress triaxiality of 1/3,while extension twinning is prevalent at the stress triaxiality of 0.Moreover,scanning electron microscopy(SEM) shows that the fracture mechanism is transformed from microvoid growth and coalescence to internal void shearing as the stress triaxiality decreases from 1/3 to 0. | Hongchen Pan Fenghua Wang Li Jin Miaolin Feng Jie Dong | 2016 | Journal of Materials Science & Technology2016，32，12： | 3 |
| 3 | Glimepiride induces proliferation and differentiation of rat osteoblasts via the PI3-kinase/Akt pathway显示文摘 | Pan Ma Bin Gu Junli Ma Lingling E Xia Wu Junkai Cao Hongchen Liu | 2010 | Metabolism2010，，3： | 1 |
| 4 | Dendrimer modified magnetite nanoparticles for protein immobilizeation显示文摘 | PAN Bifeng FENG Gao GU Hongchen | 2005 | Journal of Colloid and Interface Science2005，，284： | 1 |
| 5 | Generation of multiple stress waves in silica glss in high fluence femtosecond laser abation 显示文摘 | Hu Haofeng Wang Xiaolei Zhai Hongchen Zhang Nan Wang Pan | 2010 | Applied Physics Letters2010，97，06： | 1 |
| 6 | Dendrimer modified magnetite nanop articles for protein immobiliz-ation显示文摘 | Pan Bifeng Gao Feng Gu Hongchen | 2005 | Journal of Colloid and Interface Science2005，，284： | 1 |
| 7 | Expert consensus on odontogenic maxillary sinusitis multi-disciplinary treatment显示文摘Odontogenic maxillary sinusitis (OMS) is a subtype of maxillary sinusitis (MS). It is actually inflammation of the maxillary sinus that secondary to adjacent infectious maxillary dental lesion. Due to the lack of unique clinical features, OMS is difficult to distinguish from other types of rhinosinusitis. Besides, the characteristic infectious pathogeny of OMS makes it is resistant to conventional therapies of rhinosinusitis. Its current diagnosis and treatment are thus facing great difficulties. The multi-disciplinary cooperation between otolaryngologists and dentists is absolutely urgent to settle these questions and to acquire standardized diagnostic and treatment regimen for OMS. However, this disease has actually received little attention and has been underrepresented by relatively low publication volume and quality. Based on systematically reviewed literature and practical experiences of expert members, our consensus focuses on characteristics, symptoms, classification and diagnosis of OMS, and further put forward multidisciplinary treatment decisions for OMS, as well as the common treatment complications and relative managements. This consensus aims to increase attention to OMS, and optimize the clinical diagnosis and decision-making of OMS, which finally provides evidence-based options for OMS clinical management. | Jiang Lin Chengshuo Wang Xiangdong Wang Faming Chen Wei Zhang Hongchen Sun Fuhua Yan Yaping Pan Dongdong Zhu Qintai Yang Shaohua Ge Yao Sun Kuiji Wang Yuan Zhang Mu Xian Ming Zheng Anchun Mo Xin Xu Hanguo Wang Xuedong Zhou Luo Zhang | 2024 | International Journal of Oral Science2024，16，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员