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| 1 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit显示文摘 | Juliana Barr Gilles L. Fraser Kathleen Puntillo E. Wesley Ely Céline Gélinas Joseph F. Dasta Judy E. Davidson John W. Devlin John P. Kress Aaron M. Joffe Douglas B. Coursin Daniel L. Herr Avery Tung Bryce R. H. Robinson Dorrie K. Fontaine Michael A. Ramsa | 2013 | Critical Care Medicine2013，，1： | 6 |
| 2 | CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath显示文摘钙绑定酷氨酸调整 phosphorylation 的蛋白质(CABYR ) 是高度多态的钙绑定 tyrosine-/threonine-phosphorylated 和 serine-/threonine-phosphorylated 涉及 capacitation 的含纤维的鞘(FS ) 蛋白质。一个通常认为的领域(氨基酸 12 鈥 ? 8 ) 对类型 II 营地依赖者蛋白质 kinase A (RII ) dimerisation 和抛锚 kinase 蛋白质(AKAP ) 的规章的子单元相应在 N 终点的蛋白质 kinase A 的有约束力的领域建议那 CABYR 可以自我装配并且绑在 AKAP。而且,有证据, CABYR 与 AKAP 限制了相互作用。然而,推进在 CABYR 之间的证据和新关系,包括 AKAP,另外的 FS 蛋白质将在理解 FS 的基本生理学是有用的。在这研究,为不可溶解的蛋白质的 co-immunoprecipitation 的新策略,以及在有集体 spectrometry 和西方的污点的联合的标准 co-immunoprecipitation 方法,被采用探索在 CABYR, AKAP3 和 Ropporin 之间的关系。结果证明 AKAP3 是有由 anti-CABYR-A polyclonal 抗体的 CABYR 的 co-immunoprecipitated,并且,相反地, CABYR 也是有由 anti-AKAP3 polyclonal 抗体的 AKAP3 的 co-immunoprecipitated。包含蛋白质的另一象 RII 一样域, Ropporin,也是有 CABYR 的 co-immunoprecipitated,显示 Ropporin 是 CABYR 的绑定之一合伙。在 CABYR, AKAP3 和 Ropporin 之间的相互作用被酵母证实二混血儿的试金。进一步的分析显示出那 CABYR 不仅由它的 RII 领域绑在 AKAP3 而且除象 RII 一样领域以外通过另外的区域绑在 Ropporin。这是 CABYR 变体形成的第一示范不仅有 scaffolding 蛋白质 AKAP3 而且与在人的精子 FS 的另一象 RII 一样包含域的蛋白质的建筑群。 | Yan-Feng Li Wei He Arabinda Mandal Young-Hwan Kim Laura Digilio Ken Klotz Charles J Flickinger John C Herr | 2011 | Asian Journal of Andrology2011，13，2： | 5 |
| 3 | Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors显示文摘AIM:To evaluate the long-term natural history of the gastroduodenal lesions secondary to extrahepatic embolization with Ytrium 90(90 Y) spheres.METHODS:From September 2003 to January 2012,379 procedures of liver radioembolization(RE) using resin microspheres loaded with 90 Y were performed in our center.We have retrospectively compiled the data from 379 RE procedures performed in our center.We report a comprehensive clinical,analytical,endoscopic and histologic long-term follow-up of a series of patients who developed gastroduodenal lesions after the treatment.RESULTS:Six patients(1.5%) developed gastrointestinal symptoms and had gastrointestinal lesions as shown by upper endoscopy in the next 12 wk after RE.The mean time between RE and the appearance of symptoms was 5 wk.Only one patient required endoscopic and surgical treatment.The incidence of gastrointestinal ulcerations was 3.75%(3/80) when only planar images were used for the pre-treatment evaluation.It was reduced to 1%(3/299) when singlephoton emission computed tomography(SPECT) images were also performed.The symptoms that lasted for a longer time were nausea and vomiting,until 25 mo after the treatment.CONCLUSION:All patients were free from severe symptoms at the end of follow-up.The routine use of SPECT has decreased the incidence of gastrointestinal lesions due to unintended deployment of 90 Y particles. | Iago Rodríguez-Lago Cristina Carretero Maite Herráiz José C Subtil Maite Betés Macarena Rodríguez-Fraile Jesús J Sola José I Bilbao Miguel Muoz-Navas Bruno Sangro | 2013 | World Journal of Gastroenterology2013，19，19： | 2 |
| 4 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit显示文摘 | Juliana Barr Gilles L. Fraser Kathleen Puntillo E. Wesley Ely Céline Gélinas Joseph F. Dasta Judy E. Davidson John W. Devlin John P. Kress Aaron M. Joffe Douglas B. Coursin Daniel L. Herr Avery Tung Bryce R. H. Robinson Dorrie K. Fontaine Michael A. Ramsa | 2013 | Critical Care Medicine2013，，1： | 2 |
| 5 | Two-dimensionalgel electrophoretie analysis of vectorially labeled surface proteins of human spermatozoa 显示文摘 | Naaby Hansen S Flickinger C J Herr J C | 1997 | Biol Reprod1997，56，3： | 1 |
| 6 | A rapid Ychromosome-detecting bovine embryo sexing assay显示文摘 | HERR C M MATTHAEI K I PETRZAK U | 1990 | Theriogenology1990，33，1： | 1 |
| 7 | Ion-gated electron transfer in self-assembled monolayer films 显示文摘 | Campbell D J Herr B R Hulteen J C | 1996 | J Am Chem Soc1996，118，10： | 1 |
| 8 | Modulation of floral development by a gibberellin -regulated microRNA 显示文摘 | Achard P Herr A Baulcombe D C | 2004 | Development2004，131，14： | 1 |
| 9 | Field trial to evaluate immunogenicity of a glycoprotein I (gE) - deleted pseudorabies virus vaccine after its administration in the presence ofmaternal antibodies显示文摘 | Weigel R M Lehman J R Herr L Hahn E C | 1995 | Am J Vet Res1995，56，9： | 1 |
| 10 | Evaluation of the revised faces pain scale, verbal descriptor sclae, numeric rating scale, and iowa pain thermometer in older minority adults显示文摘 | WARE L J EPPS C D HERR K | 2006 | Pain Manag Nurs2006，7，： | 1 |
| 11 | Alpha-1 antitrypsin is elevated in exhaled breath condensate and serum in exacerbated COPD patients显示文摘 | Koczulla A R Noeske S Herr C | 2012 | Respiratory medicine2012，106，1： | 1 |
| 12 | Standardization of radical cystectomy and pelvic lymph node dissection for bladder cancer: A collaborative group report 显示文摘 | HERR H LEE C CHANG S | 2004 | J Urol2004，171，5： | 1 |
| 13 | Cross-resistance of CD95-and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)显示文摘 | Los M Herr I Friesen C | 1997 | Blood1997，90，8： | 1 |
| 14 | Effectiveness of ractopamine hydrochloride on growth performance, carcass composition and sensory characteristics in heavy weight finishing swine 显示文摘 | Herr C T Autrey B A Carr S N | 2007 | Journal of Animal Science2007，，85： | 1 |
| 15 | Effectiveness of ractopam in ehydroch loride on growth performance, carcass composition and sensory characteristics in heavy weight finishing swine显示文摘 | HERR C T A~Y B A CARR S N | 2007 | Journal of Animal Science2007，87，： | 1 |
| 16 | Physicians Appeals on the Dangers of Mobile Communication-what is the Evidence? Assessment of Public Health Data显示文摘 | Nieden A Z Dietz C Eikmann T Kiefer J Herr C E W | 2009 | International Journal of Hygiene and Environmental Health2009，，212： | 1 |
| 17 | Model calcula- tions of total maximum daily loads of mercury for drainage lakes显示文摘 | CHEN C W HERR J W GOLDSTEIN R A | 2008 | Journal of the American Water Resources Associa- tion2008，44，5： | 1 |
| 18 | Concurrent therapies that protect against doxombicin-induced eardiomyopathy 显示文摘 | Simpson C Herr H Courville K A | 2004 | Clin J Oneol Nuts2004，8，5： | 1 |
| 19 | Microbiological hydroxylation of mono-cyclic alcohols显示文摘 | HERR M E MURRAY H C | 1967 | J Am Chem Soc1967，89，3： | 1 |
| 20 | Volutionary Ecol-Ogy of Figs and Their Associates: Recent Progress and Out-Standing Puzzles 显示文摘 | HERRE E A JANDER K C MACHADO C A E | 2008 | Annual Review of Ecology Evolution and Systematics2008，39，： | 1 |
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