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| 1 | Chemostratigraphy of Flood Basalts in the Garze-Litang Region and Zongza Block: Implications for Western Extension of the Emeishan Large Igneous Province, SW China显示文摘The Late Permian Emeishan Large Igneous Province (ELIP) is commonly regarded as being located in the western part of the Yangtze craton, SW China, with an asymmetrical shape and a small area. This area, however, is just a maximum estimation because some parts of the ELIP were not recognized or dismembered and destroyed during the Triassic to Cenozoic tectonism. In this paper, the chemostratigraphical data of the Zongza block, the Garze-Litang belt and the Songpan-Garze block suggest that the Late Permian basalts in these areas have remarkable similarities to the ELIP basalts in petrography and geochemistry. Flood basalts in the Sanjiangkou area are composed of the lower part of the low-Ti (LT) tholeiite and the upper part of the high-Ti (HT) tholeiite, which is the same as the flood basalts on the western margin of the Yangtze craton. Flood basalts in the Zongza and Songpan-Garze areas, which are far from the Yangtze craton, consist of HT tholeiite only. This is the same as the flood basalts within the Yangtze craton. Therefore we argue that these contemporary basalts all originated from the Emeishan mantle plume, and the ELIP could have a significant westward extension with an outcropped area of over 500,000 km^2. This new scenario shows that the LT tholeiite occurs on the western margin of the Yangtze craton, while the HT tholeiite overlying the LT basalts occupies the whole area of the ELIP. | XIAOLong XUYigang XUJifeng HEBin PirajnoFRANCO | 2004 | Acta Geologica Sinica(English Edition)2004，78，1： | 18 |
| 2 | Helium Isotope Geochemistry of Ultrahigh-Pressure Metamorphic Eclogites From the Dabie-Sulu Terrane in East China显示文摘The 3He/4He ratios of most eclogites from the Dabie-Sulu terrane range from 0.056 to 0.67 Ra; the data points fall into the mixing part of the crust and the mantle in the 3He-4He diagram. The 3He/4He ratios of eclogites are obviously correlated with the types of their surrounding rocks. The helium isotope composition of the eclogites from the Bixiling complex possesses characters of mantle-derived rocks with the 3He/4He ratio being 5.6 Ra. The 4He concentration of the eclogites exhibits visible inverse correlation with the δ18O value of the quartz in the eclogites from the Sulu area. The δ18O values of the eclogites change synchronously with those of the country rocks. Those results suggest that protoliths of the eclogites were basic-ultrabasic rock bodies or veins intruding into the continental crust in the early stage; strong exchange and hybridization between the basic-ultrabasic rocks and continental rocks and the atmospheric water during the intrusion led to abrupt increase of the 3He/4He ratios, | LI Yanhe LI Jincheng SONG Hebin LIU Xiaochun | 2000 | Acta Geologica Sinica(English Edition)2000，74，1： | 12 |
| 3 | New Development of the Basic Theory of Extenics显示文摘In this paper, the new development of three basic theories of Extenics, including basic element theory, extension set theory and extension logic theory, has been introduced. And the new theoretical frame of Extenics has also been set forth. | CaiWen YangChunyan ZhaoYan HeBin | 2004 | 工程科学(英文版)2004，2，1： | 6 |
| 4 | Prognostic significance of preoperative Naples prognostic score on short-and long-term outcomes after pancreatoduodenectomy for ampullary carcinoma显示文摘Background:The Naples prognostic score(NPS)is an effective and objective tool to assess the immune-nutritional status of patients with malignant tumors.The aim of this study was to investigate the clinical significance of preoperative NPS on short-and long-term outcomes after pancreatoduodenectomy(PD)for ampullary carcinoma.Methods:We retrospectively analyzed 404 consecutive patients with ampullary carcinoma who underwent PD between January 2012 and June 2018.Preoperative NPS was calculated from serum albumin and total cholesterol concentrations,and the neutrophil-lymphocyte ratio and lymphocyte-monocyte ratio(LMR).Patients were then divided into three groups according to their NPS.Clinicopathological variables,postoperative outcomes,and survival data were compared between the three groups.Univariate and multivariate Cox analysis of overall survival(OS)and recurrence-free survival(RFS)were also conducted,and time-dependent receiver operating characteristic(ROC)curves were created to evaluate the discriminatory ability of the prognostic scoring systems.Results:Patients with higher NPS had worse prognosis,and significant OS difference(group 0 vs.1,P=0.02;group 1 vs.2,P<0.001;group 0 vs.2,P<0.001)and RFS difference(group 0 vs.1,P=0.088;group 1 vs.2,P<0.001;group 0 vs.2,P<0.001).Multivariate analysis revealed that NPS was an independent significant predictor of OS(grade 2 vs.grade 1 or 0,hazard ratio:3.067;P<0.001)and RFS(grade 2 vs.grade 1 or 0,hazard ratio:2.732;P<0.001).The time-dependent receiver operating curve analysis showed that NPS had better prognostic performance for OS and RFS than other prognostic models.Additionally,significant differences in the incidence of postoperative morbidity were observed between the three groups,and the NPS was an independent risk factor of overall postoperative complications(grade 2 vs.grade 1 or 0,odds ratio:1.692;P=0.02).Conclusions:The NPS was an independent predictor of overall-and RFS in patients undergoing PD for ampullary carcinoma,and was independently associated with the incidence of postoperative complications. | Jikuan Jin Hebin Wang Feng Peng Xiaoxiang Wang Min Wang Feng Zhu Guangbing Xiong Renyi Qin | 2021 | Hepatobiliary Surgery and Nutrition2021，10，6： | 5 |
| 5 | Characteristics of authigenic pyrite and its sulfur isotopes influenced by methane seep at Core A, Site 79 of the middle Okinawa Trough显示文摘The anaerobic oxidation of methane(AOM) has strongly developed at Core A, Site 79 of the middle Okinawa Trough, East China Sea, and a large amount of authigenic pyrite is preserved in the surface sediment. In this study, we analyze the characteristics of the authigenic pyrite and its sulfur isotopic values. The authigenic pyrite is stripy and tubular, and there were foraminifera compartments filled with pyrite. The pyrite is extracted using chromium reduction, and the values of ? 34 S are found to lie between ?41.20‰ and 8.92‰ V-CDT. The bulk pyrite tends to be more enriched in 34 S with increasing depth. Particularly, the ? 34 S value of the pyrite lies between ?32.73‰ and ?41.20‰ V-CDT above 278 cmbsf, but it quickly increases below this depth(?21.49‰–8.92‰ V-CDT). At the same time, the total sulfur content of the pyrite shows an abrupt increase above 100 cmbsf but is otherwise stable between 1.04% and 0.55% below 100 cmbsf. The stable and negative values of ? 34 S and the decreasing values of total sulfur above 278 cmbsf indicate reduced AOM activities in 17.18–5.3 ka. In addition, the increasing ? 34 S and pyrite content indicate strong AOM development and methane seep below 278 cmbsf in 18.8–17.18 ka. In particular, the highest positive value of ? 34 S occurring in 18.78 ka indicates the most intense AOM activity. The shallow sulfate-methane interface(SMI) and high methane flux below marine sediments also strongly support this activity. | WANG Meng CAI Feng LI Qing LIANG Jie YAN GuiJing DONG Gang WANG Feng SHAO HeBin HU GaoWei | 2015 | Science China Earth Sciences2015，58，12： | 4 |
| 6 | Geochemical constraints on the methane seep activity in western slope of the middle Okinawa Trough, the East China Sea显示文摘Anaerobic oxidation of methane and sulfate reduction was studied in the pore waters of four cores at two stations of the middle Okinawa Trough. Pore water vertical distributions of sulfate, methane, sulfide, total alkalinity, ammonium, and phosphate were determined in this study. Our results show strong linear sulfate concentration gradients of 6.83 mmol/L m?1 in Core A and 5.96 mmol/L m?1 in Core C, which were collected from two stations. Concurrent variations of methane, total alkalinity and hydrogen sulfide all exhibit steep increases with depth at both cores, which indicate active methane seep activities around two stations. Pore water ammonium and phosphate concentrations reveal minor influences of organic matter degradation on sulfate reduction at two stations. Sulfate methane interface(SMI) was extrapolated from linear sulfate profiles in methane seep cores. Shallower SMI depths(A: 4.9 mbsf; C: 5.4 mbsf) indicate strong methane fluxes and active anaerobic oxidation of methane in the underlying sediments. | LI Qing CAI Feng LIANG Jie SHAO HeBin DONG Gang WANG Feng YANG ChuanSheng HU GaoWei | 2015 | Science China Earth Sciences2015，58，6： | 3 |
| 7 | Molecular Design of Synthetic Biodegradable Polymersas Cell Scaffold Materials显示文摘Poly(lactic acid) and its copolymers are regarded as the most useful biomaterials. The good biocompatibility, biodegradability and mechanical properties of them make the synthetic biodegradable polymers have primary application to tissue engineering. The advantages and disadvantages of the synthetic biodegradable polymers as cell scaffold materials are evaluated. This article reviews the modification of polylactide-family aliphatic polymers to improve the cell affinity when the polymers are used as cell scaffolds. We have developed four main approaches: to modify polyester cell scaffolds in combination of plasma treating and collagen coating; to introduce hydrophilic segments into aliphatic polyester backbones; to introduce pendant functional groups into polyester chains; to modify polyester with dextran. The results of the cell cultures prove that the approaches mentioned above have improved the cell affinity of the polyesters and have modulated cell function such as adhesion, proliferation and migration. | WANGShen-guo WANYu-qing CAIQing HEBin CHENWen-na | 2004 | Chemical Research in Chinese Universities2004，20，2： | 3 |
| 8 | Extreme Enrichment of Tellurium in Deep-Sea Sediments显示文摘Tellurium is a sort of scattered rare element on the earth. Its concentration is very low in earth’s crust, only 1.0 ng/g. However, it has extremely high abundance in Co-rich crusts, marine polymetallic nodules, deep-sea sediments and aerolites. To find out the origin of tellurium enrichment in deep-sea sediments, we analyzed and compared tellurium concentrations and helium isotope compositions in the magnetic parts and those in the bulk parts of deep-sea sediments. The result indicates that the helium content, 3He/4He ratio and tellurium concentration are obviously higher in the magnetic parts than those in the bulk parts. The 3He abundance varies synchronously with the tellurium concentration. 3He and Te have a distinct positive correlation with each other. It is the first time that the paper brings forward that the extreme enrichment of tellurium in deep-sea sediments, like helium isotope anomalies, probably results from the input of interplanetary dust particles (IDPs). Similarly, the extreme enrichment of tellurium in marine polymetallic nodules and Co-rich crusts is possibly related to IDPs. | LI Yanhe WANG Yimin SONG Hebin YUE Guoliang | 2005 | Acta Geologica Sinica(English Edition)2005，79，4： | 3 |
| 9 | Plasmacytoid dendritic cell deficiency in neonates enhances allergic airway inflammation via reduced production of IFN-α显示文摘Allergic asthma,a chronic inflammatory airway disease associated with type 2 cytokines,often originates in early life.Immune responses at an early age exhibit a Th2 cell bias,but the precise mechanisms remain elusive.Plasmacytoid dendritic cells(pDCs),which play a regulatory role in allergic asthma,were shown to be deficient in neonatal mice.We report here that this pDC deficiency renders neonatal mice more susceptible to severe allergic airway inflammation than adult mice in an OVA-induced experimental asthma model.Adoptive transfer of pDCs or administration of IFN-αto neonatal mice prevented the development of allergic inflammation in wild type but not in IFNAR1−/−mice.Similarly,adult mice developed more severe allergic inflammation when pDCs were depleted.The protective effects of pDCs were mediated by the pDC-/IFN-α-mediated negative regulation of the secretion of epithelial cell-derived CCL20,GM-CSF,and IL-33,which in turn impaired the recruitment of cDC2 and ILC2 cells to the airway.In asthmatic patients,the percentage of pDCs and the level of IFN-αwere lower in children than in adults.These results indicate that impairment of pDC-epithelial cell crosstalk in neonates is a susceptibility factor for the development of allergeninduced allergic airway inflammation. | Min Wu Liuchuang Gao Miao He Hangyu Liu Han Jiang Ketai Shi Runshi Shang Bing Liu Shan Gao Hebin Chen Feili Gong Erwin WGelfand Yafei Huang Junyan Han | 2020 | Cellular & Molecular Immunology2020，17，5： | 3 |
| 10 | Widespread Methane Seep Activities along the Western Slope of the Okinawa Trough, East China Sea显示文摘Objective The western slope of the Okinawa trough has been considered to experience important methane seep activities.Abundant terrigenous sediments supply and widely developed normal faults make this area an ideal place for methane production,methane fluids migration and associated anaerobic oxidation of methane.However,few studies have been performed to reveal the methane seep activities via pore water geochemical studies in this area.In this study,we present comprehensive | LI Qing CAI Feng YAN Guijing LIANG Jie SHAO Hebin WANG Meng DONG Gang WANG Feng SUN Yunbao LUO Di | 2017 | Acta Geologica Sinica(English Edition)2017，91，4： | 2 |
| 11 | Removal of Cadmium Ions from Aqueous Solution by Silicate-incorporated Hydroxyapatite显示文摘这篇文章作为过去常把镉离子从水溶液移开的一种新环境矿物质在 silicate-incorporatedhydroxyapatite 上报导初步的研究。合并硅酸盐的 hydroxyapatite 被一起沉淀准备并且锻烧,并且硅酸盐被磷酸盐的部分替换合并到 hydroxyapatite 的晶体点阵。离子由合并硅酸盐的 hydroxyapatite 移开的镉的数量显著地被提高,它比纯 hydroxya 的高是 76%但是合并硅酸盐的 hydroxyapatite 上的镉离子的吸着行为类似于揭示的纯 hydroxyapatite.Morphological 学习的那硅酸盐加入限制了水晶生长并且增加了 hydroxyapatite 的比面积区域,它赞成提高样品的镉离子吸着能力。进 hydroxyapatite 的硅酸盐的加入似乎是一条有效途径在水的镉离子的移动上改进 hydroxyapatite 的环境性质。 | SHI Hebin ZHONG Hong LIU Yu DENG Jinyang | 2007 | Acta Geologica Sinica(English Edition)2007，81，3： | 2 |
| 12 | A watershed-based adaptive knowledge system for developing ecosystem stakeholder partnerships显示文摘This study proposes a Watershed-based Adaptive Knowledge System(WAKES) to consistently coordinate multiple stakeholders in developing sustainable partnerships for ecosystem management.WAKES is extended from the institutional mechanism of Payments for Improving Ecosystem Services at the Watershed-scale(PIES-W).PIES-W is designed relating to the governance of ecosystem services flows focused on a lake as a resource stock connecting its inflowing and outflowing rivers within its watershed.It explicitly realizes the values of conservation services provided by private land managers and incorporates their activities into the public organizing framework for ecosystem management.It implicitly extends the 'upstream-to-downstream' organizing perspective to a broader vision of viewing the ecosystems as comprised of both 'watershed landscapes' and 'marine landscapes'.Extended from PIES-W,WAKES specifies two corresponding feedback:Framework I and II.Framework I is a relationship matrix comprised of three input-output structures of primary governance factors intersecting three subsystems of a watershed with regard to ecosystem services and human stakeholders.Framework II is the Stakeholder-and-Information structure channeling five types of information among four stakeholder groups in order to enable the feedbacks mechanism of Framework I.WAKES identifies the rationales behind three fundamental information transformations,illustrated with the Transboundary Diagnostic Analysis and the Strategic Action Program of the Bermejo River Binational Basin.These include(1) translating scientific knowledge into public information within the Function-and-Service structure corresponding to the ecological subsystem,(2) incorporating public perceptions into political will within the Serviceand-Value structure corresponding to the economic subsystem,and(3) integrating scientific knowledge,public perceptions and political will into management options within the Value-and-Stakeholder structure corresponding to the social subsystem.This study seeks to share a vision of social adaptation for a global sustainable future through developing a network to adopt contributions from and forming partnerships among all ecosystem stakeholders. | Hebin LIN Jeffrey A.THORNTON Nickolai SHADRIN | 2015 | Chinese Journal of Oceanology and Limnology2015，33，6： | 2 |
| 13 | Overexpression and characterization of a thermostable β-agarase producing neoagarotetraose from a marine isolate Microbulbifer sp.AG1显示文摘An agarase gene containing 1 302 bp was cloned from Microbulbifer sp. AG1. It encoded a mature protein of 413 amino acids plus a 20-residue signal peptide. The recombinant enzyme without the signal peptide was expressed and purified from Escherichia coli BL21(DE3). When agarose was used as a substrate, the optimal temperature and pH for the enzyme were 60℃ and 7.5, respectively. The recombinant agarase showed excellent thermostability with 67% and 19% of residual activities after incubation at 50℃ and 60℃ for 1 h, respectively.Except SDS, the recombinant agarase had a relatively good resistance against the detected inhibitors, detergents and urea denaturant. Thin layer chromatography analysis and enzyme assay using p-nitrophenyl-α/β-Dgalactopyranoside revealed that the recombinant agarase was a β-agarase that degraded agarose into neoagarotetraose as the main end product. The enzymatic hydrolysis products with different degree of polymerization exhibited the antioxidant activities. | Yanbing Zhu He Gao Hebin Li Hui Ni Zedong Jiang Lijun Li Anfeng Xiao | 2019 | Acta Oceanologica Sinica2019，38，2： | 1 |
| 14 | 显示文摘 | GuZhongwei(顾忠伟) LuoKui(罗奎) SheWenchuan(余汶川) WuYao(吴尧) HeBin(何斌) | | 中国科学0，，： | 1 |
| 15 | Characteristics of Authigenic Pyrite and its Sulfur Isotopes Influenced by Methane Seep--Taking the Core A at Site 79 of the Middle Okinawa Trough as an Example显示文摘Objective Authigenic pyrite often develops extensively in marine sediments,which is an important product of sulfate reduction in an anoxic environment.It has a specific appearance and complicated sulfur isotopic properties,and acts as important evidence of methane seep in marine sediments.Strong AOM(anaerobic oxidation of methane) | WANG Meng LI Qing CAI Feng LIANG Jie YAN Guijing DONG Gang WANG Feng SHAO Hebin LUO Di CAO Yimin | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 1 |
| 16 | A continuous simulation of Holocene effective moisture change represented by variability of virtual lake level in East and Central Asia显示文摘The fluctuation of a single lake level is a comprehensive reflection of water balance within the basin, while the regional consistent fluctuations of lake level can indicate the change of regional effective moisture. Previous researches were mainly focused on reconstructing effective moisture by multiproxy analyses of lake sediments. We carried out a series of experiments, including a transient climate evolution model, a lake energy balance model and a lake water balance model to simulate continuous Holocene effective moisture change represented by variability of virtual lake level in East and Central Asia.The virtual lake level, area, water depth and salinity are not equivalent to actual values, but we estimated relative changes of the regional effective moisture. We also explored the driving mechanisms of effective moisture change in different geographical regions. Our results indicated that gradually falling effective moisture during the Holocene in northern China was due to the combined effects of high lake evaporation caused by longwave and shortwave radiation, and low precipitation caused by reductions of summer solar insolation. A decline in effective moisture through the Holocene in the Tibetan Plateau and southern Central Asia resulted from decreased precipitation because of the weakening of the Asian summer monsoon. Increased precipitation induced by the strengthening of the westerly circulation contributed to the effective moisture rise during the Holocene in northern Central Asia. | Yu LI Yuxin ZHANG Xinzhong ZHANG Wangting YE Lingmei XU Qin HAN Yichan LI Hebin LIU Simin PENG | 2020 | Science China Earth Sciences2020，63，8： | 1 |
| 17 | 显示文摘 | XuXianghui(徐翔晖) LiCaixia(李彩侠) LiHaiping(李海平) LiuRons(刘荣) JiangChao(江超) WuYao(吴尧) HeBin(何斌) GuZhongwei(顾忠伟) | | 中国科学0，，： | 1 |
| 18 | Preparation and Characterization of Nucleus/Shell TiO_2/HAP Complex Nanophotocatalyst显示文摘一个快速、更有效的方法被开发准备 nucleus/shelltitania/hydroxyapatite ( TiO /HAP )与 0.1 mol/L HCI 有 beendissolved 的复杂 nanophotocatalyst.Hydroxyapatite ( 5 亩 m )在 nanosized anatasetitania 粉末 byincreasing 的表面上被形成在在水洗澡为的 90 deg C 的解决方案的 pH 值仅仅产生样品的几 hours.Themicrostructure 和形态学被 X-raydiffraction ( XRD )调查,Fourier变换红外线的光谱学(英尺红外)。 | Hongfei LIU Xiaonong CHENG Juan YANG Xuehua YAN Hebin SHI | 2007 | Journal of Materials Science & Technology2007，23，1： | 1 |
| 19 | A 3D bio-printed spheroids based perfusion in vitro liver on chip for drug toxicity assays显示文摘Liver is the foremost organ of human being for drug metabolism,and it played a significant role in toxicity evaluation of drugs.Establishing a liver model in vitro can accelerate the process of the drug screening and new drug research and development.We provide a 3D printing based hepatic sinusoid-on-a-chip microdevice that reconstitutes organ-level liver functions to create a drug screening model of toxicity evaluation on chip.The microfluidic device,which recapitulates the hepatic sinusoid microenvironment,consists of PET polyporous membranes which mimic the perisinusoidal space,and experience fluid flow to mimic the hepatic arterial capillaries.The PET membrane was used to separate the hepatocyte and endotheliocyte.The endotheliocyte was cultured on the downside of the membrane and the hepatocyte were 3D seeded on the membrane via the 3D printer.This device was used to reproduce the in vitro liver model for drug toxicity assays.The expression of several biomarkers of liver was compared with the monoculture and 2D cultured conditions,and the results reveal that this organ-on-a-chip microdevice mimics the drug hepatoxicity that has not been possible by 2D cell-based and animal models,providing a useful platform for screening the drugs and developing an effective therapy in hepatopathy. | Tian Tian Yuhan Ho Chen Chen Hebin Sun Janan Hui Panhui Yang Yuqing Ge Ting Liu Jian Yang Hongju Mao | 2022 | Chinese Chemical Letters2022，33，6： | 1 |
| 20 | Extraterrestrial3 He in marine polymetallic nodules: A potential method for measuring growth rate of nodules显示文摘 | Yanhe Li Hebin Song Jincheng Li | 2002 | Science in China Series B: Chemistry2002，，1： | 1 |
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