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| 1 | Special Section:SARS-CoV-2 Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19显示文摘Effective therapies are urgently needed for the SARS-CoV-2 pandemic.Chloroquine has been proved to have antiviral effect against coronavirus in vitro.In this study,we aimed to assess the efficacy and safety of chloroquine with different doses in COVID-19.In this multicenter prospective observational study,we enrolled patients older than 18 years old with confirmed SARS-CoV-2 infection excluding critical cases from 12 hospitals in Guangdong and Hubei Provinces.Eligible patients received chloroquinephosphate s00 mg,orally,once(half dose)or twice(full dose)daily.Patients treated with non-chloroquine therapy were included as historical controls.The primary endpoint is the time to undetectable viral RNA.Secondary outcomes include the proportion of patients with undetectable viral RNA by day 10 and 14,hospitalization time,duration of fever,and adverse events.A total of 197 patients completed chloroquine treatment,and 176patients were included as historical controls.The median time to achieve an undetectable viral RNA was shorter in chloroquine than in non-chloroquine(absolute difference in medians-6.0 days;95%CI-6.0 to—4.0).The duration of fever is shorter in chloroquine(geometric mean ratio 0.6;95%CIO.5 to 0.8).No serious adverse events were observed in the chloroquine group.Patients treated with half dose experienced lower rate of adverse events than with full dose.Although randomized trials are needed for further evaluation,this study provides evidence for safety and efficacy of chloroquine in COVID-19 and suggests that chloroquine can be a cost-effective therapy for combating the COVID-19 pandemic. | Mingxing Huang Man Li Fei Xiao Pengfei Pang Jiabi Liang Tiantian Tang Shaoxuan Liu Binghui Chen Jingxian Shu Yingying You Yang Li Meiwen Tang Jianhui Zhou Guanmin Jiang Jingfen Xiang Wenxin Hong Songmei He Zhaoqin Wang Jianhua Feng Changqing Lin Yinong Ye Zhilong Wu Yaocai Li Bei Zhong Ruilin Sun Zhongsi Hong Jing Liu Huili Chen Xiaohua Wang Zhonghe Li Duanqing Pei Lin Tian Jinyu Xia Shanping Jiang Nanshan Zhong Hong Shan | 2020 | National Science Review2020，7，9： | 20 |
| 2 | Biomass production,nutrient cycling and distribution in age-sequence Chinese fir(Cunninghamia lanceolate)plantations in subtropical China显示文摘Biomass production and nutrient(N, P, K, Ca and Mg) accumulation, distribution and cycling were quantified in young, mature and over-mature(10-, 22-, and34-year old) Chinese fir [Cunninghamia lanceolate(Lamb.) Hook] plantations in southern China. Total stand biomass of young, mature and over-mature stands was 38,104 and 138 t ha-1respectively. Biomass production increased significantly with age. Stem wood represented the highest percentage of stand biomass, accounting for 41,55 and 63 % in the young, mature and over-mature plantations respectively. Nutrients concentration was highest in live needles and branches, and lowest in stem wood. The plantations accumulated more N, followed by K, Ca, Mg,and P. Nutrient return amount, nutrient utilization efficiency, nutrient turnover time, the ratio of nutrient returnand uptake increased with stand age, which implies that young Chinese fir deplete soil nutrients to maintain growth,and efficiently utilize nutrients to decrease dependence on soil nutrients as they age. Harvesting young Chinese fir plantations would therefore lead to high nutrient loss, but prolonging the rotation length could improve soil recovery,and help sustain productivity in the long-term. Improved nutrient return through litterfall as stands get older may also be beneficial to nutrient pool recovery. | Lili Zhou Addo-Danso Daniel Shalom Pengfei Wu Zongming He Chunhua Liu Xiangqing Ma | 2016 | Journal of Forestry Research2016，27，2： | 13 |
| 3 | Unequal-thickness billet optimization in transitional region during isothermal local loading forming of Ti-alloy rib-web component using response surface method显示文摘Avoiding the folding defect and improving the die filling capability in the transitional region are desired in isothermal local loading forming of a large-scale Ti-alloy rib-web component(LTRC). To achieve a high-precision LTRC, the folding evolution and die filling process in the transitional region were investigated by 3 D finite element simulation and experiment using an equal-thickness billet(ETB). It is found that the initial volume distribution in the second-loading region can greatly affect the amount of material transferred into the first-loading region during the second-loading step, and thus lead to the folding defect. Besides, an improper initial volume distribution results in non-concurrent die filling in the cavities of ribs after the second-loading step, and then causes die underfilling. To this end, an unequal-thickness billet(UTB) was employed with the initial volume distribution optimized by the response surface method(RSM). For a certain eigenstructure, the critical value of the percentage of transferred material determined by the ETB was taken as a constraint condition for avoiding the folding defect in the UTB optimization process,and the die underfilling rate was considered as the optimization objective. Then, based on the RSM models of the percentage of transferred material and the die underfilling rate, non-folding parameter combinations and optimum die filling were achieved. Lastly, an optimized UTB was obtained and verified by the simulation and experiment. | Ke WEI Mei ZHAN Xiaoguang FAN He YANG Pengfei GAO Miao MENG | 2018 | Chinese Journal of Aeronautics2018，31，4： | 13 |
| 4 | Percent free prostate-specific antigen for prostate cancer diagnosis in Chinese men with a PSA of 4.0-10.0 ng/mL:Results from the Chinese Prostate Cancer Consortium显示文摘Objective:To test the diagnostic performance of percent free prostate-specific antigen(%fPSA)in predicting any prostate cancer(PCa)and high-grade prostate cancer(HGPCa)in a retrospective multi-center biopsy cohort with a PSA level of 4.0e10.0 ng/mL in China.Methods:Consecutive patients with a PSA of 4.0-10.0 ng/mL who underwent transrectal ultrasound-guided biopsy were enrolled at 16 Chinese medical centers from January 1st,2010 to December 31st,2013.Total and free serum PSA determinations were performed using three types of electro-chemiluminescence immunoassays recalibrated to the World Health Organization(WHO)standard.The diagnostic accuracy of PSA,%fPSA,and %fPSA in combination with PSA(%fPSA t PSA)was determined using the area under the receiver operating characteristic(ROC)curve(AUC).Results:A total of 2310 consecutive men with PSA levels between 4.0 and 10.0 ng/mL were included,and the detection rate of PCa was 25.1%.The AUC of%fPSA and %fPSA t PSA in predicting any PCa was superior to PSA alone in men aged≥60 years(0.623 vs.0.534,p<0.0001)but not in men aged 40e59 years(0.517 vs.0.518,p=0.939).Similar result was yield in predicting HGPCa.Conclusion:In a clinical setting of Chinese men with 4.0e10.0 ng/mL PSA undergoing initial prostate biopsy,adding %fPSA to PSA can moderately improve the diagnostic accuracy for any PCa and HGPCa compared with PSA alone in patients≥60 but not in patients aged 40-59 years. | Rui Chen Liping Xie Xiaobing Cai Yiran Huang Liqun Zhou Lulin Ma Xu Gao Chuanliang Xu Shancheng Ren Pengfei Shao Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Li Lu Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tie Zhou Fubo Wang Biming He Yinghao Sun | 2015 | Asian Journal of Urology2015，2，2： | 8 |
| 5 | The apparent contact angle of water droplet on the micro-structured hydrophobic surface显示文摘The apparent contact angle of Cassie-Baxter state water droplets can be calculated by the existing theoretical formula, but due to the defects of the micro-structured hydrophobic surface and some inevitable tiny disturbances in the experiment, Cassie-Baxter state water droplets will appear partly in Wenzel state, that is, the mixed state water droplets. In this paper, apparent contact angles of Cassie-Baxter state and mixed state water droplets on micro-structured hydrophobic surfaces are compared. The research shows that if the projected area fraction of water-solid F in the Cassie-Baxter formula is replaced by the local projected area fraction of water-solid F′, the apparent contact angles of water droplets in both Cassie-Baxter state and the mixed state can be calculated. Further experimental results indicate that the contact state of water droplets nearby the outermost three-phase contact line plays a more important role in determining the apparent contact angle. This conclusion is significant to the understanding of the apparent contact angle and wetting property. | YANG ChangWei, HE Feng & HAO PengFei School of Aerospace, Tsinghua University, Beijing 100084, China | 2010 | Science China Chemistry2010，53，4： | 8 |
| 6 | Experimental study of rotating gliding arc discharge plasma-assisted combustion in an aero-engine combustion chamber显示文摘The combustion chamber is the core component of an aero-engine, and affects its reliability and security operation, even the performance of the aircraft. In this work, a Plasma-Assisted Combustion(PAC) test platform was developed to validate the feasibility of using PAC actuators to enhance annular combustor performance. Two plans of PAC(rotating gliding arc discharge plasma) were designed, Assisted Combustion from Primary Holes(ACPH) and Assisted Combustion from Dilution Holes(ACDH). Comparative experiments and analysis between conventional combustion and PAC were conducted to study the effects of ACPH and ACDH on the performances including average outlet temperature, combustion efficiency, pattern factor under four different excessive air coefficients(0.8, 1, 2, and 4), and lean blowout performance at different inlet airflow velocities. Experimental results show that the combustion efficiency is improved after PAC compared with that in normal conditions, and the combustion efficiency of ACPH increases2.45%, 1.49%, 1.04%, and 0.47%, while it increases 2.75%, 1.67%, 1.36%, and 0.36% under ACDH conditions. The uniformity of the outlet temperature field and the lean blowout performance are improved after PAC. Especially for ACPH, the widening of the lean blowout limit is8.3%, 12.4%, 12.8%, and 25% respectively when the inlet velocity ranges from 60 m/s to120 m/s. These results offer new perspectives for using PAC devices to enhance aero-engine combustors' performances. | Liming HE Yi CHEN Jun DENG Jianping LEI Li FEI Pengfei LIU | 2019 | Chinese Journal of Aeronautics2019，32，2： | 8 |
| 7 | Long-term treadmill exercise inhibits neuronal cell apoptosis and reduces tau phosphorylation in the cerebral cortex and hippocampus of aged rats显示文摘Aging is an inevitably spontaneous process of the creature.With the increase of age,physical function is degraded in the elderly.One of the most common degradation is memory loss and cognitive impairment in brain function.Neuron loss and neurofibrillary tangles formation contributes to brain dysfunction.Neuron loss is associated with neuronal cell apoptosis.Apoptosis is a process | Guoliang Fang Jiexiu Zhao Pengfei Li Liang Li Tao Yu Xingya Yang Zihong He Ye Tian | 2017 | Science Bulletin2017，62，11： | 7 |
| 8 | A Simple Approach to Bioconjugation at Diverse Levels: Metal-Free Click Reactions of Activated Alkynes with Native Groups of Biotargets without Prefunctionalization显示文摘Te efcient bioconjugation of functional groups/molecules to targeted matrix and bio-related species drives the great development of material science and biomedicine,while the dilemma of metal catalysis,uneasy premodifcation,and limited reaction efciency in traditional bioconjugation has restricted the booming development to some extent.Here,we provide a strategy for metal-free click bioconjugation at diverse levels based on activated alkynes.As a proof-of-concept,the abundant native groups including amine,thiol,and hydroxyl groups can directly react with activated alkynes without any modifcation in the absence of metal catalysis.Trough this strategy,high-efcient modifcation and potential functionalization can be achieved for natural polysaccharide,biocompatible polyethylene glycol(PEG),synthetic polymers,cell penetrating peptide,protein,fast whole-cell mapping,and even quick diferentiation and staining of Gram-positive bacteria,etc.Terefore,current metal-free click bioconjugation strategy based on activated alkynes is promising for the development of quick fuorescence labeling and functional modifcation of many targets and can be widely applied towards the fabrication of complex biomaterials and future in vivo labeling and detection. | Xianglong Hu Xueqian Zhao Benzhao He Zheng Zhao Zheng Zheng Pengfei Zhang Xiujuan Shi Ryan T.K.Kwok Jacky W.Y.Lam Anjun Qin Ben Zhong Tang | 2018 | Research2018，，1： | 7 |
| 9 | The FGOALS climate system model as a modeling tool for supporting climate sciences:An overview显示文摘Climate system models are useful tools for understanding the interactions among the components of the climate system and predicting/projecting future climate change. The development of climate models has been a central focus of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics, Institute of Atmospheric Physics, Chinese Academy of Sciences(LASG/IAP) since the establishment of the laboratory in 1985. In China, many pioneering component models and fully coupled models of the climate system have been developed by LASG/IAP. The fully coupled climate system developed in the recent decade is named FGOALS(Flexible Global Ocean-Atmosphere-Land System Model). In this paper, an application-oriented review of the LASG/IAP FGOALS model is presented. The improved model performances are demonstrated in the context of cloud-radiation processes, Asian monsoon, ENSO phenomena, Atlantic Meridional Overturning Circulation(AMOC) and sea ice. The FGOALS model has contributed to both CMIP5(Coupled Model Intercomparison Project-phase 5) and IPCC(Intergovernmental Panel on Climate Change) AR5(the Fifth Assessment Report). The release of FGOALS data has supported the publication of nearly 500 papers around the world. The results of FGOALS are cited ~106 times in the IPCC WG1(Working Group 1) AR5. In addition to the traditional long-term simulations and projections, near-term decadal climate prediction is a new set of CMIP experiment, progress of LAGS/IAP in the development of nearterm decadal prediction system is reviewed. The FGOALS model has supported many Chinese national-level research projects and contributed to the national climate change assessment report. The crucial role of FGOALS as a modeling tool for supporting climate sciences is highlighted by demonstrating the model's performances in the simulation of the evolution of Earth's climate from the past to the future. | TianJun Zhou Bin Wang YongQiang Yu YiMin Liu WeiPeng Zheng LiJuan Li Bo Wu PengFei Lin Zhun Guo WenMin Man Qing Bao AnMin Duan HaiLong Liu XiaoLong Chen Bian He JianDong Li LiWei Zou XiaoCong Wang LiXia Zhang Yong Sun WenXia Zhang | 2018 | Earth and Planetary Physics2018，2，4： | 6 |
| 10 | Application of chemical vapor-deposited monolayer ReSe2 in the electrocatalytic hydrogen evolution reaction显示文摘 | Shaolong Jiang Zhepeng Zhang Na Zhang Yahuan Huan Yue Gong Mengxing Sun Jianping Shi Chunyu Xie Pengfei Yang Qiyi Fang He Li Lianming Tong Dan Xie Lin Gu Porun Liu Yanfeng Zhang | 2018 | Nano Research2018，11，4： | 6 |
| 11 | Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B显示文摘作为克积极的、形成孢子的厌氧的杆菌, Clostridium 顽固(C。顽固) 为严重、致命的 pseudomembranous 大肠炎负责,并且形成世界范围的最迫切的抗菌素抵抗威胁。流行 C。顽固全球性是联系抗菌素的腹泻的领先的原因,特别由于 hypervirulent 的出现,种类与高死亡和病态联系了的腹泻。TcdB,关键毒力因素之一由这个细菌藏匿了,通过糟糕理解的机制进入主人房间得到它的病原的效果。这里,我们报导 TcdB 细胞的受体的第一鉴定, chondroitin 硫酸盐 proteoglycan 4 (CSPG4 ) 。CSPG4 开始从屏蔽的一个整个染色体的人的 shRNAmir 图书馆被孤立,并且它的角色被证实由调停 TALEN 并且在人的房间的 CRISPR/Cas9-mediated 基因大美人。CSPG4 为对房间表面有约束力的 TcdB 是批评的,导致细胞骨架混乱和房间死亡。在 CSPG4 的 N 终点和 TcdB 的 C 终点之间的一个直接相互作用被证实,并且 CSPG4 的毒素绑定领域的可溶的肽能保护房间免受 TcdB 的行动的伤害。尤其是, CSPG4/NG2 的完全的损失减少了在没有显著地影响动物死亡的老鼠的被触发 TcdB 的 interleukin-8 正式就职。基于两个在里面 vitro 并且在 vivo 研究,我们为 TcdB endocytosis 建议一个双受体的模型。第一 TcdB 受体的发现为 CSPG4 揭示一个以前不受怀疑的角色并且为 C 的处理提供一个新治疗学的目标。顽固感染。 | Pengfei Yuan Hongmin Zhang Changzu Cai Shiyou Zhu Yuexin Zhou Xiaozhou Yang Ruina He Chan Li Shengjie Guo Shan Li Tuxiong Huang Gregorio Perez-Cordon Hanping Feng Wensheng Wei | 2015 | Cell Research2015，25，2： | 6 |
| 12 | Key Techniques for the Construction of High-Speed Railway Large-Section Loess Tunnels显示文摘 | Yong Zhao Huawu He Pengfei Li | 2018 | Engineering2018，4，2： | 6 |
| 13 | Molecular phylogeny and divergence time of Trachypithecus: with implications for the taxonomy of T. phayrei显示文摘 | Kai HE Naiqing HU Joseph D.ORKIN Daw Thida NYEIN Chi MA Wen XIAO Pengfei FAN Xuelong JIANG | 2012 | Zoological Research2012，33，6： | 5 |
| 14 | In vitro and in vivo biocompatibility of Mg–Zn–Ca alloy operative clip显示文摘At present,titanium(Ti)and its alloys are most commonly use in hemostasis clip clinical applications.However,the Ti Clip cannot be absorbed in human body and produce artifacts on computed tomography(CT),and induce clinically relevant hypersensitivity in patients.In order to overcome the drawbacks of the non-degradable Ti clips,an Mg-Zn-Ca alloy operative clip was fabricated by combining hot extrusion and blanking processing.In vitro and in vivo biocompatibility of Mg-Zn-Ca alloy operative clip were evaluated by L-929 Cells and SD rat model respectively.It was found that Mg-Zn-Ca alloy exhibited non-cytotoxic to L929 cells.In vivo implantation showed that the newly designed Mg-Zn-Ca clip can successfully ligated carotid artery and no blood leakage occurred post-surgery.During the period of the clip degradation,a small amount of H2 gas formation and no tissue inflammation around the clips were observed.The degradation rate of the clip near the heart ligated the arteries faster than that of clip far away the heart due do the effect of arterial blood.Histological analysis and various blood biochemical parameters in rat serum samples collected at different times after clip implantation showed no tissue inflammation around the clips. | Pengfei Ding Yuanchao Liu Xianghui He Debao Liu Minfang Chen | 2019 | Bioactive Materials2019，4，1： | 5 |
| 15 | Wearable CNT/Ti_(3)C_(2)T_(x)MXene/PDMS composite strain sensor with enhanced stability for real-time human healthcare monitoring显示文摘Strain sensors with good stability are vital to the development of wearable healthcare monitoring systems.However,the design of strain sensor with both duration stability and environmental stability is still a challenge.In this work,we propose an ultra-stable and washable strain sensor by embedding a coupled composite film of carbon nanotube(CNT)and Ti_(3)C_(2)T_(x) MXene into polydimethylsiloxane(PDMS)matrix.The composite strain sensor with embedded microstructure and uneven surface makes it conformal to skin,while the CNT/MXene sensing layer exhibits a resistance sensitive to strain.This sensor shows reliable responses at different frequencies and with long-term cycling durability(over 1,000 cycles).Meanwhile,the CNT/MXene/PDMS composite strain sensor provides the advantages of superior anti-interference to temperature change and water washing.The results demonstrate less than 10%resistance changes as the temperature rises from-20 to 80℃or after sonication in water for 120 min,respectively.The composite sensor is applied to monitor human joint motions,such as bending of finger,wrist and elbow.Moreover,the simultaneous monitoring of the electrocardiogram(ECG)signal and joint movement while riding a sports bicycle is demonstrated,enabling the great potential of the as-fabricated sensor in real-time human healthcare monitoring. | Xiaowen Xu Yucheng Chen Pei He Song Wang Kai Ling Longhui Liu Pengfei Lei Xianjun Huang Hu Zhao Jianyun Cao Junliang Yang | 2021 | Nano Research2021，14，8： | 5 |
| 16 | Dataset of the plasma membrane proteome of nasopharyngeal carcinoma cell line HNE1 for uncovering protein function显示文摘鼻咽的癌(NPC ) 是在南部的中国和东南亚洲的一个通常发生的肿瘤。当前的学习集中了于为 NPC 房间线 HNE1 的外部、不可分的蛋白质开发一个广泛的分析方法。外部膜蛋白质被 biotinylated 丰富提取, 0.1 M Na 2 公司 3, 和 H 2 O。不可分或全部的血浆膜部分用 30% Percoll 密度等级 centrifugation 被准备与或没有 0.1 M Na 2 公司 3 处理并且由西方的污点分析评估了。蛋白质受到与双人脚踏车团 spectrometry,与双人脚踏车团 spectrometry 相结合的钠 dodecyl sulfate-polyacrylamide 胶化电气泳动,和猎枪分析相结合的二维的电气泳动。我们分别地从外部、不可分、全部的血浆膜部分识别了 371, 180,和 702 蛋白质。总共, 848 非冗余的蛋白质(534 个组) 被识别。有约束力、催化、结构的分子是主要的班。除了 NPC 房间的已知的房间表面标记,分析在癌症房间是特征的疾病小径揭示了涉及多重发信号房间的小径的 311 蛋白质和 25 蛋白质。由寻找,差别表示了蛋白质数据库(http://gffzze0f623e48f094866h9pvxnx9909pb6bwu.ffgz.tsg.suse.edu.cn/depd/index.jsp ) , 199 蛋白质被发现是在以前的癌症 proteome 研究表示的差别。671 蛋白质蛋白质相互作用网络被获得,包括在这个工作的 178 识别蛋白质。五蛋白质的血浆膜本地化被免疫学的技术证实,验证这 proteomic 策略。我们的学习能为理解 NPC 的分子的机制提供一些帮助。 | Lijun Zhang Xiaofang Jia Xiaohui Liu Tingting Sheng Rui Cao Quanyuan He Zhen Liu Xia Peng JixianXiong Pengfei Zhang Ni Shi Songping Liang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，1： | 5 |
| 17 | Physiological responses of needles of Pinus massoniana elite families to phosphorus stress in acid soil显示文摘Pinus massoniana Lamb. is a major timber species widely planted in the South China, where the soil is acidic and deficient in phosphorus (P) due to fixation by aluminum and iron. Understanding the physiological responses to rhizospheric insoluble P is essential for enhancing plantation productivity. Thus, a sand culture experiment was conducted with four levels of P treatment (0, 5, 20 g insoluble P and 10 g soluble P), and 11 P. massoniana elite families. Physiological responses were measured after two months of stress. Compared to the normal soluble P treatment, the insoluble P treatment significantly reduced the proline content and the APase activity in the needles, while it significantly increased the catalase activity by 1.3-fold and malondialdehyde content by 1.2-fold. Soluble protein content was unaffected by the treatments, but chlorophyll content was significantly lower in P-deprived treatment compared with soluble and insoluble P treatments. These physiological responses also exhibited highly significant variation among families (p < 0.01). The findings suggest that increased catalase activities in the presence of insoluble P might be involved in the activation of an anti-oxidation defense mechanism that scavenges the reactive oxygen species elicited by the stress. And this response has a strong genetic control that can be exploited to identify desirable genotypes. | HE You-lan LIU Ai-qin Mulualem Tigabu WU Pengfei MA Xiang-qing WANG Chen Per Christer Oden | 2013 | Journal of Forestry Research2013，24，2： | 4 |
| 18 | 152 W high-power blue diode laser operated at 447 nm显示文摘We demonstrate a high-power blue diode laser operated at 447 nm combining laser diodes using an optical fiber bundle. As many as 127 diode lasers at 447 nm were coupled into 400 μm/0.22 NA fibers using an aspherical lens group with different focus lengths. The bare fibers were mechanically bundled through high temperature ultraviolet adhesive after the coatings of the 127 fibers were stripped. The diameter of the fiber bundle was 6 mm. The total output power of such a bundle was 152 W with electro-optical conversion efficiency of 27.56%and the RMS power instability was less than ±1% within 3 h. | Peng Wu Ling Zhang Haijuan Yu Xiandan Yuan Zhiyan Zhang Pengfei Zhao Shuzhen Zou Chaojian He Yaoyao Qi Yingying Yang Gang Li Xubao Wang Xuechun Lin | 2017 | Journal of Semiconductors2017，38，7： | 4 |
| 19 | Circular cladding waveguides in Pr:YAG fabricated by femtosecond laser inscription:Raman,luminescence properties and guiding performance显示文摘We report on the fabrication of circular cladding waveguides with cross-section diameters of 60−120μm in Pr:YAG crystal by applying femtosecond laser inscription.The fabricated waveguides present 2D guidance on the cross-section and fairly low propagation losses.Multiple high-order guiding modes are observed in waveguides with different diameters.Corresponding simulation results reveal the origin of a specific kind of guiding modes.Confocal micro-Raman(μ-Raman)experiments demonstrate the modification effects in femtosecond laser affected areas and ascertain the refractive index induced guiding mechanism.In addition,luminescence emission properties of Pr3+ions at waveguide volume are well preserved during the femtosecond laser inscription process,which may result in a potential high-power visible waveguide laser. | Quanxin Yang Hongliang Liu Shan He Qingyu Tian Bin Xu Pengfei Wu | 2021 | Opto-Electronic Advances2021，4，2： | 4 |
| 20 | Cloning and Expression Analysis of Citrus Genes Cs GH3.1 and Cs GH3.6Responding to Xanthomonas axonopodis pv. citri Infection显示文摘To study the functions of the early auxin-responsive genes Cs GH3.1 and Cs GH3.6 in citrus resistance against canker disease, we cloned Cs GH3.1and Cs GH3.6 in ‘Newhall' Navel Orange(Citrus sinensis Osbeck). They are 1 797 bp and 1 887 bp and encode 598 and 629 amino acids, respectively. In vitro mature leaves from susceptible ‘Newhall' and resistant Calamondin(C. madurensis) were inoculated by a Xanthomonas axonopodis pv. citri(Xac) bacterial suspension, and expression of Cs GH3.1 and Cs GH3.6 in the two varieties were analyzed using quantitative real-time PCR(q RT-PCR). ‘Newhall' leaves were treated with different hormones for 3 days, inoculated by Xac bacterial suspension, and then the symptoms in these leaves were investigated. We used q RT-PCR to analyze the effect of different hormones on Cs GH3.1 and Cs GH3.6 expression in ‘Newhall'leaves. The expression levels of both Cs GH3.1 and Cs GH3.6 were significantly induced by Xac in ‘Newhall' leaves, compared with levels in Calamondin leaves. 1-naphthy acetic acid(NAA) increased the hypertrophy of infection sites in ‘Newhall' leaves, while naphthyl-phthalamic acid(NPA)had no visible effect on lesion development. NAA hormone greatly improved expression of Cs GH3.1 in ‘Newhall', but not Cs GH3.6. These results indicate that the auxin primary-response gene Cs GH3.1 plays an important role in citrus susceptibility to Xac. | CHEN Min HE Yongrui XU Lanzhen PENG Aihong LEI Tiangang YAO Lixiao LI Qiang ZHOU Pengfei BAI Xiaojing DUAN Minjie JIANG Xueyou JIA Ruirui ZOU Xiuping CHEN Shanchun | 2016 | Horticultural Plant Journal2016，2，4： | 4 |
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