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| 1 | 仙人掌果提取液对卵巢癌的抑制作用显示文摘目的:研究仙人掌果提取液在动物体内和体外对卵巢癌的抑制作用。方法:用Crystalviolet方法测定、细胞周期分析及细胞凋亡TUNEL分析观察仙人掌果提取液在体外对卵巢癌细胞生长的抑制作用;仙人掌果提取液对人卵巢癌的动物模型的治疗效果。结果:2种卵巢癌细胞(OVCA420和SKOV3)对于不同浓度仙人掌果提取液反应敏感程度不同,IC50分别是0·8%和8%,正常卵巢上皮细胞(IOSE)的IC50为2%;仙人掌果提取液可以有效的抑制卵巢癌在动物体内的生长(P<0·05),与N-(4-hydroxyphernyl)retinamide(4HPR)作用相似(P>0·05)。结论:仙人掌果提取液对体外卵巢癌细胞生长和动物体内的卵巢癌生长均有明显抑制作用。 | 邹大明 刘华钢 Molly Brewer Jean M Feugang 梁秋云 Kenneth D. Hatch Changping Zou | 2008 | 广西医学院学报2008，18，2： | 3 |
| 2 | Analysis of the ferroelectric phase transition in BaAl2O4 by group theoretical methods and first-principles calculations 显示文摘 | Stokes H T Sadate C Hatch D M | 2002 | Phys Rev B2002，65，06： | 2 |
| 3 | Should antibiotics be administered before arthroscopic knee surgery? A systematic review of the literature显示文摘AIM To explore the current evidence surrounding the administration of prophylactic antibiotics for arthroscopic knee surgery. METHODS Databases were searched from inception through May of 2018 for studies examining prophylactic antibiotic use and efficacy in knee arthroscopy. Studies with patient data were further assessed for types of arthroscopic procedures performed,number of patients in the study,use of antibiotics,and outcomes with the intention of performing a pooled analysis. Data pertaining to 'deep tissue infection' or 'septic arthritis' were included in our analysis. Reported data on superficial infection were not included in our data analysis. For the pooled analysis,a relative risk ratio was calculated and χ~2 tests were used to assess for statistical significance between rates of infection amongst the various patient groups. Post hoc power analyses were performed to compute the statistical power obtained from our sample sizes. Number needed to treat analyses were performed for statistically significant differences by dividing 1 by the difference between the infection rates of the antibiotic and no antibiotic groups. An alpha value of 0.05 was used for our analysis. Study heterogeneity was assessed by Cochrane's Q test as well as calculation of the I^2 value.RESULTS A total of 49682 patients who underwent knee ar-throscopy for a diverse set of procedures across 19 studies met inclusion critera for pooled analysis. For those not undergoing graft procedures,there were 27 cases of post-operative septic arthritis in 34487 patients(0.08%) who received prophylactic antibiotics and 16 cases in 10911(0.15%) who received none [risk ratio(RR) = 0.53,95% confidence interval(CI): 0.29-0.99,P = 0.05]. A sub-group analysis in which bony procedures were excluded was performed which found no significant difference in infection rates between patients that received prophylactic antibiotics and patients that did not(P > 0.05). All anterior cruciate ligament reconstruction studies used prophylactic antibiotics,but two studies investigating the effect of soaking the graft in vancomycin in addition to standard intravenous(IV) prophylaxis were combined for analysis. There were 19 cases in 1095 patients(1.74%) who received IV antibioitics alone and no infections in 2034 patients who received IV antibiotics and had a vancomycin soaked graft(RR = 0.01,95%CI: 0.001-0.229,P < 0.01).CONCLUSION Prophylactic antibiotics are effective in preventing septic arthritis following simple knee arthroscopy. In procedures involving graft implantation,graft soaking reduces the rate of infection. | John Carney Nathanael Heckmann Erik N Mayer Ram K Alluri Carleton Thomas Vangsness George F Hatch Ⅲ Alexander E Weber | 2018 | World Journal of Orthopedics2018，9，11： | 2 |
| 4 | Medial temporal lobe abnormalities in pediatric unipolar depression显示文摘 | Sheila C. Caetano Manoela Fonseca John P. Hatch Rene L. Olvera Mark Nicoletti Kristina Hunter Beny Lafer Steven R. Pliszka Jair C. Soares | 2007 | Neuroscience Letters2007，，3： | 2 |
| 5 | Model development for piezoceramic nanopositioners显示文摘 | Smith R C Hatch Andrew De Tathagata | 2003 | Proceedings of the 42nd IEEE Conference on Decision and Control2003，，： | 1 |
| 6 | The Dynamics of Organizational Identity显示文摘 | Mary Jo Hatch Majken Schultz | 2002 | Human Relations2002，，： | 1 |
| 7 | A frame less stereotaxic integration of computerized to mographic imaging and the operating microscope显示文摘 | Roberts DW Strohlaehm JW Hatch JF | 1986 | J Neurosurg1986，65，4： | 1 |
| 8 | Manternal mortality of new York显示文摘 | Hatch Mc | 1969 | J Med1969，69，： | 1 |
| 9 | A frameless stereotaxic integration of computerized tomographic imag ing and the operating microscope显示文摘 | Roberts DW Strohbehn JW Hatch JF | 1986 | J Neurosurg1986，65，4： | 1 |
| 10 | Laparoscopic assisted surgical staging (LASS) of endometrial cancer显示文摘 | Childers JM Brzechffa PR Hatch KD | 1993 | Gynecol Oncol1993，51，： | 1 |
| 11 | Celecoxib as an ad- junct in the treatment of depressive or mixed episodes of bipo- lar disorder: a double-blind, randomized, placebo-controlled study显示文摘 | Nery FG Monkul ES Hatch JP | 2008 | Hum Psychopharmacol2008，23，2： | 1 |
| 12 | Relationship between inferred redox potential of the depositional environment and geochem- istry of the Upper Pennsylvanian (Missourian) stark shale mem-ber of the Dennis Limestone,Wabaunsee County,Kansas, USA 显示文摘 | HATCH J R LEVENTHAL J S | 1992 | Chemical Geology1992，99，13： | 1 |
| 13 | Intestinal transport of an obdurate anion : ox- alate显示文摘 | Hatch M Freel RW | 2005 | Urol Res2005，33，： | 1 |
| 14 | Comparison of α-amylase activities from different assay methods显示文摘 | Yoo Y J Hong J Hatch R T | 1987 | Biotechnology and Bioengineering1987，30，1： | 1 |
| 15 | The Benefits of A Scorecard System 显示文摘 | LAWSON R STRATTON W HATCH T | 2003 | CMA Management2003，，： | 1 |
| 16 | Quantification of basal and stimulated ROS levels as predictors of islet potency and function显示文摘 | AMANN B HANSON M S HATCH E | 2007 | Am J Transplant2007，7，1： | 1 |
| 17 | Aflatoxin exposure and risk of hepatocellular carcinoma in Taiwan显示文摘 | Wang LY Hatch M Chen CJ | 1996 | Int J Cancer1996，67，5： | 1 |
| 18 | Reproductive and Hormonal Factors and Risk of Brain Tumor in Adult Females显示文摘 | Hatch E E Linet M S Zhang J Y | 2005 | Int J Cancer2005，114，： | 1 |
| 19 | feces and feathers can indicateintra-individual changes in the diet of migratory songbirds 显示文摘 | Podlesak D W McWilliams S R Hatch K A Stable isotopes in breath blood | 2005 | OecoLogia2005，142，4： | 1 |
| 20 | Researchingcorporate social responsibility:an agenda for the 21st century显示文摘 | Godfrey P.C Hatch N.W | | 0，，： | 1 |
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