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| 1 | Repeated cupping manipulation temporary decreases natural killer lymphocyte frequency, activity and cytotoxicity显示文摘OBJECTIVE: Elevated natural killer lymphocyte cytotoxicity(NKc) has been linked with reproductive problems in women. Here we evaluate the potential benefit of cupping therapy(CT) in reproductionrelated immune responses.METHODS: This was a pilot clinical study. Participants were he althy fe male volunteers(n = 23) with elevated NKc, and received repeated CT 3 times over 5 d(inner pressure 40–50 kPa, 40 min; 12–1 5 cups). Lymphocyte subsets, NKc and NK lymphocyte activity(NKa) were measured in blood on day 0(initial levels, before the first treatment) and days 3, 10 and 17 after the last CT treatment, using the K562-stimulated CD69 expression assay.RESULTS: As a result of CT manipulations NKa was reduced on days 3 and 10, and NK percentage was reduced on day 10. NKc was most sensitive to CT treatment, resulting in their decreased counts at 3, 10 and 17 d post CT. CT treatment decreased NKc in the majority of individuals(87%), but the magnitude of the effect was variable. Out of 23 subjects 9(39.1%) had a 2–3 fold decrease of NKc on days 3, 10 and 17; 11(47.8%) started to show a decrease in NKc later, or more quickly returned to base levels; and only 3(13%) subjects displayed no effect of CT on NKc. Expectedly, no changes in T-cell subsets(CD3CD4, CD3CD8, HLADR, CD158a) were observed after CT.CONCLUSION: CT decreased NK cell numbers, their activity and cytotoxicity. Low cost, safety, noninvasive nature and ease of administration make CT a promising approach for NKc down-regulation. | Boris V.Dons' koi Viktor P.C hernyshov Dariia V.Osypchuk Sergiy M.Baksheev | 2016 | Journal of Integrative Medicine2016，14，3： | 6 |
| 2 | Seasonal variation in milk conjugated linoleic acid and Δ 9 -desaturase activity in dairy cows显示文摘 | A.L Lock P.C Garnsworthy | 2002 | Livestock Production Science2002，，1： | 2 |
| 3 | Researchingcorporate social responsibility:an agenda for the 21st century显示文摘 | Godfrey P.C Hatch N.W | | 0，，： | 1 |
| 4 | Gratitude and happiness:Development of a measure of gratitude and relationships with subjective well-being显示文摘 | Watkins P.C Woodward K Stone T Kolts R.L | | 0，，： | 1 |
| 5 | Managing extreme natural disasters in coastal areas显示文摘 | Kesavan P.C Swaminathan M.S | 2006 | Philosophical Transactions of The Royal Society A2006，，1845： | 1 |
| 6 | Designs for Environmental Scanning Systems:Tests of A Contingency Theory显示文摘 | Yasai-ardekani M Nystrom P.C | | 0，，： | 1 |
| 7 | High performance work systems in Ireland:Human resource and organizational outcomes显示文摘 | Guthrie J.P Flood P.C Liu W MacCurtain S | | 0，，01： | 1 |
| 8 | Mean-risk analysis with risk associated with below-target returns显示文摘 | Fishburn P.C | | 0，，02： | 1 |
| 9 | Communication geography:A bridge between disciplines显示文摘 | Adams P.C Jansson A | | 0，，03： | 1 |
| 10 | Image differences between prospective,first-time,and repeat visitors to the lower Rio Grande valley显示文摘 | Fakeye P.C Crompton J.L | | 0，，： | 1 |
| 11 | Multichannel Customer Management:Understanding the Research-Shopper Phenomenon显示文摘 | Verhoef P.C Neslin S.A Vroomen B | | 0，，2： | 1 |
| 12 | A methodology to esti-mate impacts of domestic policies on deforestation:compensated successful efforts for “avoided deforestation”(REDD)显示文摘 | Motel P.C R.Pirard J.L.Combes | | 0，，03： | 1 |
| 13 | Impetus for action:A cultural analy-sis of justice and organizational citizenship behavior in Chinese society显示文摘 | Farth J.L Earley P.C Lin S.C | | 0，，03： | 1 |
| 14 | Role of powder size, packing, solid loading and dispersion in colloidal processing of ceramics显示文摘 | M Subbanna P.C Kapur Pradip | 2002 | Ceramics International2002，，4： | 1 |
| 15 | Image difference between prospec-tive,firsttime,and repeat visitors to the lower Rio Grande Valley显示文摘 | Fakeye P.C Crompton J.L | | 0，，02： | 1 |
| 16 | Elastic attention:Enhanced,then sharpened response to auditory input as attentional load increases显示文摘 | Neelon M.F Williams J Garell P.C | | 0，，： | 1 |
| 17 | Transcranial DC stimulation(tDCS):A tool for double-blind sham-controlled clinical studies in brain stimulation显示文摘 | Gandiga P.C Hummel F.C Cohen L.G | | 0，，04： | 1 |
| 18 | Exploring Language Teachers’Practical Knowledge about Teaching Reading Comprehension显示文摘 | Meijer P.C Verloop N Beijaard D | | 0，，： | 1 |
| 19 | A genetic algorithm for the set covering problem显示文摘 | J.E Beasley P.C Chu | 1996 | European Journal of Operational Research1996，，2： | 1 |
| 20 | Centers of Excellence in Multinational Corporations显示文摘 | Frost T.S Birkinshaw J.M Ensign P.C | | 0，，： | 1 |
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