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1577篇 您的检索式:作者名="Hashizume"
    题名 作者 年代 出处 被引量
1Single-incision laparoscopic surgery for colorectal cancer显示文摘AIM: To determine the effect of single-incision laparoscopic colectomy(SILC) for colorectal cancer on short-term clinical and oncological outcomes by comparison with multiport conventional laparoscopic colectomy(CLC).METHODS: A systematic review was performed using MEDLINE for the time period of 2008 to December 2014 to retrieve all relevant literature. The search terms were 'laparoscopy', 'single incision', 'single port', 'single site', 'SILS', 'LESS' and 'colorectal cancer'. Publications were included if they were randomized controlled trials, case-matched controlled studies, or comparative studies, in which patients underwent single-incision(SILS or LESS) laparoscopic colorectal surgery. Studies were excluded if they were non-comparative, or not including surgery involving the colon or rectum. A total of 15 studies with 589 patients who underwent SILC for colorectal cancer were selected.RESULTS: No significant differences between the groups were noted in terms of mortality or morbidity. The benefit of the SILC approach included reduction in conversion rate to laparotomy, but there were no significant differences in other short-term clinical outcomes between the groups. Satisfactory oncological surgical quality was also demonstrated for SILC for the treatment of colorectal cancer with a similar average lymph node harvest and proximal and distal resection margin length as multiport CLC.CONCLUSION: SILC can be performed safely with similar short-term clinical and oncological outcomes as multiport CLC.yasumitsu hirano masakazu hattori kenji douden yasuhiro ishiyama yasuo hashizume 2016World Journal of Gastrointestinal Surgery2016,8,1:9
2大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini 2021英国医学杂志中文版2021,24,8:7
3Pancreatic involvement in chronic viral hepatitis显示文摘AIM: To elucidate the frequency and characteristics of pancreatic disorders in the course of chronic viral hepatitis. METHODS: We prospectively assessed the serum pancreatic enzyme levels and imaging findings in patients with chronic viral hepatitis and healthy control subjects. RESULTS: Serum amylase (t-Amy), salivary amylase (s-Amy), pancreatic amylase (p-Amy) and serum lipase levels were higher in hepatitis patients in comparison to control subjects. However, in asymptomatic viral carriers, only the serum t-Amy levels were higher than those of the controls. The levels of each enzyme rose with the progression of liver disease in patients with hepatitis B or C; whereas the levels of each enzyme within the same clinical stage of the disease did not differ between patients diagnosed with either hepatitis B or hepatitis C virus. Imaging findings demonstrated chronic pancreatitis in only 1 out of 202 patients (0.5%).CONCLUSION: Our data suggest that serum levels of pancreatic enzymes increase with the progression of liver disease in patients diagnosed with viral hepatitis. Pancreatic disease, asymptomatic in most cases, may represent an extrahepatic manifestation of chronic viral hepatitis.Yoshiki Katakura Hiroshi Yotsuyanagi Kiyoe Hashizume Chiaki Okuse Noriaki Okuse Kohji Nishikawa Michihiro Suzuki Shiro Iino Fumio Itoh 2005World Journal of Gastroenterology2005,11,23:5
4新型杀虫剂定虫隆显示文摘定虫隆是一种新的昆虫生长调节剂类杀虫剂,由日本石原产业公司发现,并与ICI-Agro汽巴-嘉基公司联合开发,现已在许多国家登记注册。定虫隆对昆虫幼虫体内几丁质合成有较强抑制作用,是一种选择性杀虫剂。对鳞翅目害虫有卓效,但对蚜虫、蝗虫等刺吸式害虫无活性,对蜜蜂等一些重要益虫安全。与传统杀虫剂无交互抗性,可用于对害虫的综合防治,是一个非常有前途的品种。一、作用方式定虫隆主要通过摄食来毒杀昆虫,高浓度时,也表现出接触毒性。定虫隆无内吸和叶部传导活性。与其他苯甲酰脲类一样。Bunji Hashizume 张敏恒 1989农药1989,28,4:5
5Comparison of HER2 gene amplification assessed by fluorescence in situhybridization and HER2 protein expression assessed by immunohistochemistry ingastric cancer显示文摘Tomonori Yano Toshihiko Doi Atsushi Ohtsu Narikazu Boku Kaoru Hashizume Mamoru Nakanishi Atsushi Ochiai 2006Oncology Reports2006,,1:4
6MK-0626,a selective DPP-4 inhibitor,attenuates hepatic steatosis in ob/ob mice显示文摘AIM:To investigate the mechanism and in vivo effects of MK-0626,a dipeptidyl peptidase-4 inhibitor,on hepatic steatosis using ob/ob mice.METHODS:We analyzed obese(ob/ob)8-wk-old male mice that had been randomly divided into two groups of ob/ob mice(n=16 each)and were treated with1.5 or 3 mg/kg MK-0626 and two control groups of untreated ob/ob mice and lean littermates(n=16 each).All mice were fed a normal chow diet with or without MK-0626 for either four or eight weeks.Blood samples were collected,and total hepatectomy was performed.RESULTS:The administration of dietary MK-0626 ameliorated the hepatic lipid accumulation in ob/ob micetreated with 3 mg/kg MK-0626(3 MK),P<0.05,vs untreated ob/ob mice(ob/ob).The MK-0626 treatment reduced the serum alanine aminotransferase levels(both treatment groups,P<0.05 vs ob/ob)and glucoses/insulin levels/calculated HOMA scores(1.5 MK,P<0.05vs ob/ob;3 MK,P<0.01 vs ob/ob)and increased the serum adiponectin levels(3 MK,P<0.05 vs ob/ob)in a dose-dependent manner.The MK-0626 treatment increased the m RNA expression of peroxisome proliferator-activated receptorα/microsomal triglyceride transfer protein(1.5 MK,P<0.05 vs ob/ob;3 MK,P<0.01vs ob/ob)but reduced the sterol regulatory element binding transcription factor-1c/fatty acid synthase/stearoyl-Co A desaturase-1(both treatment groups,P<0.01 vs ob/ob).The MK-0626 treatment increased the activity of AMP-activated protein kinase(AMPK)(both treatment groups,P<0.01 vs ob/ob).CONCLUSION:MK-0626 could attenuate hepatic steatosis through enhancing AMPK activity,inhibiting hepatic lipogenic gene expression,enhancing triglyceride secretion from liver and increasing serum adiponectin levels.Tatsuya Ohyama Ken Sato Yuichi Yamazaki Hiroaki Hashizume Norio Horiguchi Satoru Kakizaki Masatomo Mori Motoyasu Kusano Masanobu Yamada 2014World Journal of Gastroenterology2014,20,43:4
7Characteristics of alpha-synucleinopathy in centenarians显示文摘Ding ZT Wang Y Jiang YP Hashizume Y Yoshida M Mimuro M Inagaki T Iwase T 2006中国生物学文摘2006,20,8:4
8新型草坪除草剂flazasulfuron显示文摘Shjbagen(flazagulfuron)是由日本石原产业公司发现和开发的一种新型磺酰脲类除草剂,以每公顷25~100克有效成份的极低剂量芽后使用,可防除暖季草坪结缕草属和狗芽根属中的多种杂草。日本草坪杂草防除主要用芽前除草剂,如果发生后期萌发杂草或漏网杂草,可用几种芽后除草剂防除之。但这些除草剂的杀草谱相当窄,如果草坪受多种杂草的危害,需同时使用二种或二种以上除草剂。Bunji Hashizume 张文明 1992农药译丛1992,14,3:2
9Integration of Fault Analysis and Interlock Controller Synthesis for Batch Processes显示文摘在各种各样的决策之中的集成处理,例如计划,图案,和操作对动态、灵活的批生产必要。完成批生产集成,为各种各样的决策过程使用的普通模型的利用是一条有效途径。从这个观点,一个批系统由一张 Petri 网描述了的普通模型被建议。在这篇文章,为批进程的一种故障诊断技术用差错繁殖和差错分析的集成的可能性的信息被介绍,控制器合成根据 Petri 网络被讨论基于的普通模型。Susumu Hashizume Tomoyuki Yajima Yukiko Kuwashita Katsuaki Onogi 2008Chinese Journal of Chemical Engineering2008,16,1:2
10Mesenchymal stem cells for treatment of aortic aneurysms显示文摘An aortic aneurysm(AA) is a silent but life-threatening disease that involves rupture. It occurs mainly in aging and severe atherosclerotic damage of the aortic wall. Even though surgical intervention is effective to prevent rupture, surgery for the thoracic and thoraco-abdom-inal aorta is an invasive procedure with high mortality and morbidity. Therefore, an alternative strategy for treatment of AA is required. Recently, the molecular pathology of AA has been clarified. AA is caused by an imbalance between the synthesis and degradation of extracellular matrices in the aortic wall. Chronic inflam-mation enhances the degradation of matrices directly and indirectly, making control of the chronic inflamma-tion crucial for aneurysmal development. Meanwhile, mesenchymal stem cells(MSCs) are known to be ob-tained from an adult population and to differentiate into various types of cells. In addition, MSCs have not only the potential anti-inflammatory and immunosuppres-sive properties but also can be recruited into damagedtissue. MSCs have been widely used as a source for celltherapy to treat various diseases involving graft-versus-host disease, stroke, myocardial infarction, and chronicinflammatory disease such as Crohn's disease clinically.Therefore, administration of MSCs might be availableto treat AA using anti-inflammatory and immnosup-pressive properties. This review provides a summary ofseveral studies on 'Cell Therapy for Aortic Aneurysm'including our recent data, and we also discuss the pos-sibility of this kind of treatment.Aika Yamawaki-Ogata Ryotaro Hashizume Xian-Ming Fu Akihiko Usui Yuji Narita 2014World Journal of Stem Cells2014,6,3:2
11Intraoperative ultrasonographic localization of pulmonary ground-glass opacities显示文摘Ryoichi Kondo Kazuo Yoshida Kazutoshi Hamanaka Masahiro Hashizume Toshiki Ushiyama Akira Hyogotani Makoto Kurai Satoshi Kawakami Mana Fukushima Jun Amano 2009The Journal of Thoracic and Cardiovascular Surgery2009,,4:2
12Super-High Heat Flux Removal Using Sintered Metal Porous Media显示文摘Heat transfer experiments using various porous materials are performed to verify the possibility of extremely high heat flux removal (several dozens of MW/m2). The porous media introduced in this experiment are bronze particle-sintered ones and copper fibers-sintered ones that have high thermal conductivity, each of which can enhance the thermal diffusion in the porous material. From the heat transfer experiments using a non-transferred type of plasma arcjet as a high heat flux source, the steady heat removal of 66.0 MW/m2 is proved by using the bronze porous medium whose pore size and porosity are 100 μm and 0.38, respectively. Furthermore, as the result of evaluating the heat removal performance for various copper fiber porous media with the porosity from 0.5 to 0.7 and the fiber diameter from 30 to 90 μm, it is clarified that the maximum cooling performance exceeds 70.0 MW/m2 at the porosity of 0.7 and the fiber diameter of 90 μm, and that using the lower porosity material is useful for improving an evaporation rate in the porous media.Kazuhisa YUKI Jun ABEI Hidetoshi HASHIZUME Saburo TODA 2005Journal of Thermal Science2005,14,3:2
13Robot-assisted gastric surgery显示文摘Makoto Hashizume Keizo Sugimachi 2003Surgical Clinics of North America2003,,6:2
14Increases in the number of brain metastases detected at frame-fixed, thin-slice MRI for gamma knife surgery planning显示文摘Nagai A Shibamoto Y Mori Y Hashizume C Hagiwara M Kobayashi T 2010中国神经肿瘤杂志2010,8,3:2
15Effect of β-alanyl-L-histidinato zinc on differentiation of osteoblastic MC3T3-El cells: Increases in alkaline phosphatase activity and protein concentration显示文摘Masayuki Hashizume Masayoshi Yamaguchi 1994Molecular and Cellular Biochemistry1994,,1:2
16新昆虫生长调节剂——Atabron显示文摘Atabron是石原产业株式会社发现的新型昆虫生长调节剂,后与帝国化学工业公司以及汽巴-嘉基公司合作,在包括日本在内的许多国家内将其开发并商品化。 Atabron是高活性的昆虫几丁质合成抑制剂,能有效地防治蔬菜、茶叶、棉花等多种作物上的大多数鳞翅目害虫,这些害虫对常用杀虫剂产生抗性正成为严重的问题。 Atabron对蚜虫、粉虱、叶蝉等刺吸式口器害虫无活性,但对很多重要的益虫高度安全,Bunji Hashizume 李松乔 1990农药译丛1990,12,2:2
17Openings between defective endothelial cells explain tumor vessel leakiness显示文摘Hashizume H Baluk P Morikawa S 2000Am J Pathol2000,156,:1
18Surface plasmon resonance on mieroaperture vertical - cavity surface - emittin - glaser with metal grating 显示文摘SHINADA S HASHIZUME J KOYAMA F 2003Applied Physics letters2003,83,5:1
19An investigation on forced convection boiling of non-azeotropic refrigerant mixtures 显示文摘Murata K Hashizume K 1990Heat Transfer Japanese Research1990,19,2:1
20Expres-sion of multi-copy flavonoid pathway genes coincides withanthocyanin,flavonol and flavan-3 -ol accumulation of gra-pevine 显示文摘Jeong S T Goto-Yamamoto N Hashizume K 2008Vitis2008,47,3:1
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