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| 1 | Transcriptome Analysis of High-Temperature Stress in Developing Barley Caryopses: Early Stress Responses and Effects on Storage Compound Biosynthesis显示文摘高温度的应力象任何不能生活的压力一样,损害植物的生理学和发展,包括种子设定并且成熟的阶段。我们使用了调查开发大麦(Hordeum vulgare ) 的反应的 GeneChip microarray 播种的 Affymetrix 22K Barley1,称为的 caryopses 在 0.5 以后, 3,和 6 ? 热压力暴露的 h;958 导致了, 1122 镇压了空间的展出的基因和提供详细卓见进 caryopse 的早热的时间的表示模式强调回答。与存储混合物生合成和细胞生长有关的基因的下面规定为 caryopsi 的发展的一个快速的缺陷提供证据。糖和氨基酸的增加的层次为兼容溶质的生产和为存储混合物生合成的底层的导致反馈的累积是指示的。当热的主要地点强调回答,元数据分析识别了胚胎和内乳,显示颖果的中央发展函数上的短期的热应力的强壮的影响。有在 Arabidopsis 射击的热压力回答和在大麦 caryopses 的干旱压力回答的比较识别了保存并且大概热特定、颖果特定的压力应答的基因。总结,我们的数据提供一个重要基础让基因功能的进一步的调查以便为谷物庄稼作为一个模型在大麦帮助改进的热忍耐和产量的减少的损失。 | Elke Mangelsen Joachim Kilian Klaus Harter Christer Jansson Dierk Wanke Eva Sundberg | 2011 | Molecular Plant2011,4,1: | 6 |
| 2 | The Interaction of the Arabidopsis Response Regulator ARR18 with bZIP63 Mediates the Regulation of PROLINE DEHYDROGENASE Expression显示文摘作为第一并且脯氨酸降级的限制率的酶,脯氨酸 DEHYDROGENASE1 (PDH1 ) 紧在植物压力回答期间被调整,包括在 hypoosmolarity 下面的正式就职和在 waterdeficit 下面的压抑。植物受体 histidine kinases AHK,在 Arabidopsis thaliana 的二部件的系统(TCS ) 的元素,被建议由调整不同压力应答的基因在水压力回答工作。然而,有关 AHK 可得到的小 informationis 调停 phosphorelay 的下游的发信号。这里,我们证明 Arabidopsis type-B 反应管理者(ARR18 ) 当在 Arabidopsis 的一个积极渗透的压力反应管理者播种并且影响 PDH1 倡导者的活动, 18 工作,知道被 Cgroup bZIP 抄写因素控制。而且, ARR18 withbZIP63 的直接物理的相互作用被识别并且出现依赖于在 ARR18 receiverdomain 的保存 aspartate 残余的 phosphorylation。我们进一步证明 bZIP63 本身在渗透的应力之上作为种子萌芽的一个否定管理者工作。在原物的 Usingreporter 基因试金,我们证明那个 ARR18 相互作用否定地在 PDH1 倡导者上防碍 bZIP63 的 transcriptionalactivity。我们的调查结果作为基因 expressionin Arabidopsis 的对抗管理者提供新卓见进 ARR18 和 bZIP63 的功能。 | Manikandan Veerabagu Tobias Kirchler Kirstin Elgass Bettina Stadelhofer Mark Stahl Klaus Harter Virtudes Mira-Rodado Christina Chaban | 2014 | Molecular Plant2014,7,10: | 3 |
| 3 | Structure-Function Analysis of Arabidopsis thaliana Histidine Kinase AHK5 Bound to Its Cognate Phosphotransfer Protein AHP1显示文摘多步 phosphorelay (MSP ) 系统在植物和许多优核质定义一条关键信号 transduction 小径。在这个系统,外部刺激首先导致 histidine kinase 的激活,从 kinase (HKRD ) 的接收装置领域由一个 phosphoryl 组的转移列在后面到下游, cytosolic phosphotransfer 蛋白质(HP ) 。为了为这建立特性的决定因素发信号,中继系统,我们解决了植物 HKRD 的第一水晶结构, AHK5RD 在有它的血缘的 HP 之一的建筑群, AHP1。AHP1 经由停靠山脉和一个恐水病的补丁的一张突出的氢契约绑 AHK5RD。这些特征在所有 AHP 蛋白质之中被保存,但是与原核生物的描绘的另外的在结构上和真核细胞的 HP 显著地不同。AHK5RD 绑在 AHP1-3 与的表面电浆子回声实验表演类似, micromolar 亲密关系,与这发信号的建筑群的短暂性质一致。我们结构、功能的数据的关联提供第一卓见在原子水平以及与量的亲密关系数据,在植物管理 MSP 进分子的识别事件。 | Johannes Bauer Kerstin Reiss Manikandan Veerabagu Michael Heunemann Klaus Harter Thilo Stehle | 2013 | Molecular Plant2013,6,3: | 2 |
| 4 | The Anatomy of a Context-Aware Application显示文摘 | Andy Harter Andy Hopper Pete Steggles Andy Ward Paul Webster | 2002 | Wireless Networks (-)2002,,2: | 2 |
| 5 | The Root Cap Determines Ethylene-Dependent Growth and Development in Maize Roots显示文摘除对根尖端的机械损坏提供保护以外,根帽子涉及感觉并且导致改变的生长和开发的多样的外部、内部的刺激处理。这些刺激的 transduction 包括植物生长素,乙烯和细胞激动素的象那些那样的神经质的发信号的小径。这里,我们证明根帽子在玉米为延伸生长和根头发形成的导致乙烯的规定是必要的。当根帽子通过手术在荷尔蒙处理以前被移开时,外长地应用的乙烯不再能禁止延伸生长。帽子的宪法断然与根的发展中的能力相关再对乙烯作出回应。相反,根帽子的移动不做本身影响植物生长素和细胞激动素控制的生长抑制。而且,我们的半量的 RT-PCR 结果支持玉米根帽子是关于察觉到并且对象乙烯那样的荷尔蒙作出回应的高基因表示活动的一个地点的更早的调查结果。从这些数据,我们建议是胜任的建立在根的远侧的地区对乙烯作出回应的根帽子的一个新奇函数。 | Achim Hahn Roman Zimmermann Dierk Wanke Klaus Harter Hans G. Edelmann | 2008 | Molecular Plant2008,1,2: | 2 |
| 6 | The interrelationships among sex hormone concentrations, motoneuron excitability, and anterior tibial displacement in women and men显示文摘 | Hoffman M Harter R A Hayers B T | 2008 | J Athletic Training2008,43,: | 1 |
| 7 | Increased expression of toll-like receptor-2 and -4 on leukocytes from patients with sepsis显示文摘 | Harter L Mica L Stocker R | 2004 | Shock2004,22,5: | 1 |
| 8 | Antiviral treatment of cytomegalovirus infection and resistant strains 显示文摘 | Schreiber A Harter G Schubert A | 2009 | Expert Opin Pharmacother2009,10,2: | 1 |
| 9 | Triple-negative and HER2-overexpressing breast cancers exhibit an elevated risk and an earlier occurrence of cerebral metastases 显示文摘 | Heitz F Harter P Lueck HJ | 2009 | Eur J Cancer2009,45,16: | 1 |
| 10 | Specifying the role of BAK1-interacting receptor-like kinase 3 in brassinosteroid signaling显示文摘Brassinosteroids(BR) are involved in the control of several developmental processes ranging from root elongation to senescence and adaptation to environmental cues. Thus, BR perception and signaling have to be precisely regulated. One regulator is BRI1-associated kinase 1(BAK1)-interacting receptor-like kinase 3(BIR3). In the absence of BR, BIR3 forms complexes with BR insensitive 1(BRI1) and BAK1.However, the biophysical and energetic requirements for complex formation in the absence of the ligand have yet to be determined. Using computational modeling, we simulated the potential complexes between the cytoplasmic domains of BAK1, BRI1 and BIR3. Our calculations and experimental data confirm the interaction of BIR3 Rewith BAK1 and BRI1, with the BAK1 BIR3 interaction clearly favored. Furthermore, we demonstrate that BIR3 and BRI1 share the same interaction site with BAK1. This suggests a competition between BIR3 and BRI1 for binding to BAK1, which results in preferential binding of BIR3 to BAK1 in the absence of the ligand thereby preventing the active participation of BAK1 in BR signaling. Our model also suggests that BAK1 and BRI1 can interact even while BAK1 is in complex with BIR3 at an additional binding site of BAK1 that does not allow active BR signaling. | Ruth Groβeholz Anna Feldman-Salit Friederike Wanke Sarina Schulze Nina Glockner Birgit Kemmerling Klaus Harter Ursula Kummer | 2020 | Journal of Integrative Plant Biology2020,62,4: | 1 |
| 11 | Peripherally inserted central venous catheters for autologous blood progenitor cell transplantation in patients with haematological malignancies显示文摘 | Ostendorf T Bach A | 2003 | Support Care Carmer2003,11,12: | 1 |
| 12 | A distributed location system for the active office显示文摘 | HARTER A HOPPER A | 1994 | IEEE Network1994,8,1: | 1 |
| 13 | Training healthcarepersonnel for mass-casualty incidents in a virtual emergencydepartment: VED II 显示文摘 | Heinrichs W L Youngblood P Harter P | 2010 | Prehosp Disaster Med2010,25,5: | 1 |
| 14 | Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer显示文摘 | LEDERMANN J HARTER P GOURLEY C | 2012 | N Engl J Med2012,366,15: | 1 |
| 15 | The Anatomy of a Context-Aware Application 显示文摘 | Harter A Hopper A Steggles P | 2002 | Wireless Networks2002,8,2: | 1 |
| 16 | Peripherally in serted central catheter for au tologous blood progen itor cell transp lantation in patients with haematolog ica lmalign ancies显示文摘 | Harter C Ostendorf T Bach A | 2003 | Support Care Cancer2003,11,12: | 1 |
| 17 | The emergence of modern neuroscience:some implications for neurology and psychiatry显示文摘 | Cowan WM Harter DH Kandel ER | 2000 | Annu Rev Neurosci2000,23,: | 1 |
| 18 | Engineerable Compression of Ultrashort Pulses by Use of Second-harmonic- Generation in Chirped-period-poled Lithium Niobate显示文摘 | Arbore M A Galvanauskas A Harter D | 1997 | Optics Letters1997,22,: | 1 |
| 19 | Mutant human tumor suppressor p53 modulates the activation of mitogen - activated protein kinase and nuclear factor kappaB,but not c - Jun N - terminal kinase and activat- ed protein l显示文摘 | Gulati AP Yang YM Harter D | 2006 | Mol Caec2006,45,1: | 1 |
| 20 | Olaparib maintenance therapy in patients with platinum-sensitive re- lapsed serous ovarian cancer:a preplanned retrospective a- nalysis of outcomes by BRCA status in a randomised phase 2 trial显示文摘 | LEDERMANN J HARTER P GOURLEY C | 2014 | Lancet Oncol2014,15,8: | 1 |