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| 1 | Biliary strictures complicating living donor liver transplantation:Problems,novel insights and solutions显示文摘Biliary stricture complicating living donor liver transplantation(LDLT) is a relatively common complication, occurring in most transplant centres across the world. Cases of biliary strictures are more common in LDLT than in deceased donor liver transplantation. Endoscopic management is the mainstay for biliary strictures complicating LDLT and includes endoscopic retrograde cholangiography, sphincterotomy and stent placement(with or without balloon dilatation). The efficacy and safety profiles as well as outcomes of endoscopic management of biliary strictures complicating LDLT is an area that needs to be viewed in isolation, owing to its unique set of problems and attending complications; as such, it merits a tailored approach, which is yet to be well established. The diagnostic criteria applied to these strictures are not uniform and are over-reliant on imaging studies showing an anastomotic narrowing. It has to be kept in mind that in the setting of LDLT, a subjective anastomotic narrowing is present in most cases due to a mismatch in ductal diameters. However, whether this narrowing results in a functionally significant narrowing is a question that needs further study. In addition, wide variation in the endotherapy protocols practised in most centres makes it difficult to interpret the results and hampers our understanding of this topic. The outcome definition for endotherapy is also heterogenous and needs to be standardised to allow for comparison of data in this regard and establish a clinical practice guideline. There have been multiple studies in this area in the last 2 years, with novel findings that have provided solutions to some of these issues. This review endeavours to incorporate these new findings into the wider understanding of endotherapy for biliary strictures complicating LDLT, with specific emphasis on diagnosis of strictures in the LDLT setting, endotherapy protocols and outcome definitions. An attempt is made to present the best management options currently available as well as directions for future research in the area. | Harshavardhan B Rao Arjun Prakash Surendran Sudhindran Rama P Venu | 2018 | World Journal of Gastroenterology2018，24，19： | 14 |
| 2 | Endoscopic therapy for biliary strictures complicating living donor liver transplantation: Factors predicting better outcome显示文摘AIM To identify factors predicting outcome of endoscopic therapy in bile duct strictures(BDS) post living donor liver transplantation(LDLT).METHODS Patients referred with BDS post LDLT, were retrospectively studied. Patient demographics, symptoms(Pruritus, Jaundice, cholangitis), intra-op variables(cold ischemia time, blood transfusions, number of ducts used, etc.), peri-op complications [hepatic artery thrombosis(HAT), bile leak, infections], stricture morphology(length, donor and recipient duct diameters) and relevant laboratory data both pre-and post-endotherapy were studied. Favourable response to endotherapy was defined as symptomatic relief with > 80% reduction in total bilirubin/serum gamma glutamyl transferase. Statistical analysis was performed using SPSS 20.0.RESULTS Forty-one patients were included(age: 8-63 years). All had right lobe LDLT with duct-to-duct anastomosis. Twenty patients(48.7%) had favourable response to endotherapy. Patients with single duct anastomosis, aggressive stent therapy(multiple endoscopic retrogradecholagiography, upsizing of stents, dilatation and longer duration of stents) and an initial favourable response to endotherapy were independent predictors of good outcome(P < 0.05). Older donor age, HAT, multiple ductal anastomosis and persistent bile leak(> 4 wk post LT) were found to be significant predictors of poor response on multivariate analysis(P < 0.05). CONCLUSION Endoscopic therapy with aggressive stent therapy especially in patients with single duct-to-duct anastomosis was associated with a better outcome. Multiple ductal anastomosis, older donor age, shorter duration of stent therapy, early bile leak and HAT were predictors of poor outcome with endotherapy in these patients. | Harshavardhan B Rao Hasim Ahamed Suprabha Panicker Surendran Sudhindran Rama P Venu | 2017 | World Journal of Gastrointestinal Pathophysiology2017，8，2： | 3 |
| 3 | Synthesis of N-substituted-2-aminobenzothiazoles using nano copper oxide as a recyclable catalyst under ligand-free conditions in reusable PEG-400 medium显示文摘A simple and practical method for the synthesis of N-substituted-2-aminobenzothiazoles via a crosscoupling reaction of 2-iodo anilines with isothiocyanates is envisaged using nano copper oxide as a recyclable catalyst and Cs2CO3as a base in PEG-400,as a bio-degradable,reusable,inexpensive and nontoxic reaction medium,under ligand-free conditions.The present tandem process underlines environmental acceptability to access a wide range of N-substituted-2-aminobenzothiazoles in good to excellent yields. | Satish Gaddam Harshavardhan Reddy Kasireddy Karnakar Konkala Ramesh Katla Nageswar Yadavalli Venkata Durga | 2014 | Chinese Chemical Letters2014，25，5： | 2 |
| 4 | In silico Proteome-wide Amino aCid and Elemental Composition (PACE) Analysis of Expression Proteomics Data Provides A Fingerprint of Dominant Metabolic Processes显示文摘Proteome-wide Amino aCid and Elemental composition(PACE) analysis is a novel and informative way of interrogating the proteome.The PACE approach consists of in silico decomposition of proteins detected and quantifed in a proteomics experiment into 20 amino acids and fve elements(C,H,N,O and S),with protein abundances converted to relative abundances of amino acids and elements.The method is robust and very sensitive;it provides statistically reliable differentiation between very similar proteomes.In addition,PACE provides novel insights into proteome-wide metabolic processes,occurring,e.g.,during cell starvation.For instance,both Escherichia coli and Synechocystis down-regulate sulfur-rich proteins upon sulfur deprivation,but E.coli preferentially down-regulates cysteine-rich proteins while Synechocystis mainly downregulates methionine-rich proteins.Due to its relative simplicity,flexibility,generality and wide applicability,PACE analysis has the potential of becoming a standard analytical tool in proteomics. | David M. Good Anwer Mamdoh Harshavardhan Budamgunta Roman A. Zubarev | 2013 | Genomics, Proteomics & Bioinformatics2013，11，4： | 2 |
| 5 | Grid Integration of Electric Vehicles for Economic Benefits:A Review显示文摘Emissions from the internal combustion engine(ICE) vehicles are one of the primary cause of air pollution and climate change. In recent years, electric vehicles(EVs) are becoming a more sensible alternative to these ICE vehicles. With the recent breakthroughs in battery technology and large-scale production, EVs are becoming cheaper. In the near future,mass deployment of EVs will put severe stress on the existing electrical power system(EPS). Optimal scheduling of EVs can reduce the stress on the existing network while accommodating large-scale integration of EVs. The integration of these EVs can provide several economic benefits to different players in the energy market. In this paper, recent works related to the integration of EV with EPS are classified based on their relevance to different players in the electricity market. This classification refers to four players: generation company(GENCO), distribution system operator(DSO), EV aggregator, and end user. Further classification is done based on scheduling or charging strategies used for the grid integration of EVs. This paper provides a comprehensive review of technical challenges in the grid integration of EVs along with their solution based on optimal scheduling and controlled charging strategies. | Harshavardhan Patil Vaiju Nago Kalkhambkar | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，1： | 2 |
| 6 | AtRD22and AtUSPL1,members of the plant-specific BURPdomain family involved in Arabidopsis thaliana droughttolerance 显示文摘 | HARSHAVARDHAN V T VAN SON L SEILER C | 2014 | PLoS One2014，9，11： | 1 |
| 7 | AtRD22and AtUSPL1,members of the plant-specific BURPdomain family involved in Arabidopsis thaliana droughttolerance 显示文摘 | HARSHAVARDHAN V T VAN SON L SEILER C | 2014 | PLoS One2014，9，11： | 1 |
| 8 | AtRD22 and AtUSPL1, members of the plant-specific BURP do- main family involved in Arabidopsis thaliana drought toler- ance 显示文摘 | Harshavardhan V T Son L V Seiler C | 2014 | P1OS One2014，9，11： | 1 |
| 9 | Identification and functional validation of a unique set of drought induced genes preferentially expressed in response to gradual water stress in peanut显示文摘 | Govind G Harshavardhan V T Patricia J K | 2009 | Molec- ular Genetics and Genomics2009，281，： | 1 |
| 10 | Genetic diversity for grain Zn concentration in finger millet genotypes:Potential for improving human Zn nutrition显示文摘Nearly half of the world population suffers from micronutrient malnutrition,particularly Zn deficiency.It is important to understand genetic variation for uptake and translocation behaviors of Zn in relevant crop species to increase Zn concentration in edible parts.In the present study,genetic variation in grain Zn concentration of 319 finger millet genotypes was assessed.Large genetic variation was found among the genotypes,with concentrations ranging from 10 to 86 μg g^(-1)grain.Uptake and translocation studies with Zn/^(65) Zn application in 12 selected low-Zn genotypes showed wide variation in root uptake and shoot translocation,with genotypes GEC331 and GEC164 showing greater uptake and translocation.Genotypes GEC164 and GEC543 showed increased grain Zn concentration.Genotypes GEC331 and GEC164 also showed improved yield under Zn treatment.Appreciable variation in grain Zn concentration among finger millet genotypes found in this study offers opportunities to improve Zn nutrition through breeding. | Ramegowda Yamunarani Geetha Govind Venkategowda Ramegowda Harshavardhan Vokkaliga Thammegowda Shankar Ambarahalli Guligowda | 2016 | The Crop Journal2016，4，3： | 1 |
| 11 | Erbium-Doped Zirconia-Alumina Silica Glass-Based Fiber as a Saturable Absorber for High Repetition Rate Q-Switched All-Fiber Laser Generation显示文摘We propose and demonstrate a Q-switched erbium-doped fiber laser(EDFL) using an erbium-doped zirconiaalumina silica glass-based fiber(Zr-EDF) as a saturable absorber. As a 16-cm-long Zr-EDF is incorporated into a ring EDFL cavity, a stable Q-switching pulse train operating at 1565 nm wavelength is successfully obtained.The repetition rate is tunable from 33.97 kHz to 71.23 kHz by increasing the pump power from the threshold of 26 mW to the maximum of 74 mW. The highest pulse energy of 26.67 nJ is obtained at the maximum pump power. | P. Harshavardhan Reddy N. A. A. Kadir M. C. Paul S, Das A. Dhar E. I. Ismail A. A. Latiff S. W. Harun | 2017 | Chinese Physics Letters2017，34，8： | 1 |
| 12 | Predictive model for growth of Clostridium perfringens during cooling of cooked uncured beet显示文摘 | Vijay K Juneja Harry Marks Harshavardhan Thippareddi | 2008 | Food Microbiology2008，25，： | 1 |
| 13 | Buckling patterns in diamond-like carbon films显示文摘 | Lyer S B Harshavardhan K S Kumar V | 1995 | Thin Solid Films1995，，56： | 1 |
| 14 | Predictive model for growth of Clostridium perfringens during cooling of cooked uncured beef显示文摘 | Vijay K Juneja Harry Marks Harshavardhan Thippareddi | 2008 | Food Microbiology2008，25，： | 1 |
| 15 | Preparation structural and its enhanced green up-conversion luminescence in rare-earth doped CdMnS nano powders显示文摘 | Sekhar H Trivikrama Rao G Harshavardhan Reddy P | 2013 | Journal of Alloys and Compounds2013，562，： | 1 |
| 16 | Contrapuntalrole of ABA : does it mediate stress tolerance or plant growth retar-dation under long-term drought stress 显示文摘 | Sreenivasulu N Harshavardhan VT Govind G | 2012 | Gene2012，506，2： | 1 |
| 17 | Contrapuntal role of ABA: does it mediate stress tol- erance or plant growth retardation under long- term drought stress 显示文摘 | SREENIVASULU N HARSHAVARDHAN V T GOVIND G | 2012 | Gene2012，506，2： | 1 |
| 18 | Predictive model for growth of Clostridium perfringens during cooling of cooked uncured beef显示文摘 | Vijay K Juneja Harry Marks Harshavardhan Thippareddi | 2008 | Food Microbiology2008，25，： | 1 |
| 19 | Role of transarticalar screw fixation in tuberculous atlanto-axial insta- bility显示文摘 | BAPAT MR LAHIRI VJ HARSHAVARDHAN NS | 2007 | Eur Spine J2007，16，2： | 1 |
| 20 | Modeling the effect of temperature on growth of Salmonella in chicken显示文摘 | Vijay K. Juneja Martin Valenzuela Melendres Lihan Huang Vinod Gumudavelli Jeyamkondan Subbiah Harshavardhan Thippareddi | 2006 | Food Microbiology2006，，4： | 1 |
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