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| 1 | Multicomponent domino process for the synthesis of some novel 5-(arylidene)-3-((1-aryl-1H-1,2,3-triazol-4-yl)methyl)-thiazolidine-2,4-diones using PEG-400 as an efficient reaction medium and their antimicrobial evaluation显示文摘A series of novel thiazolidinedione-triazole hybrids were synthesized by one pot reaction between thiazolidine-2.4-dione,substituted aryl aldehydes,piopargyl bromide and substituted aryl azides using piperidine,CuSO_4· 5H_2O and sodium ascorbate as catalysts in PEG-400 as a highly efficient and green media.These thiazolidinedione-triazole hybrids were subjected to in vitro antibacterial activity against four strains namely.Staphylococcus aureus.Bacillus subtilis,Escherichia coli,Pseudomonas aeruginosa and antifungal activity against two fungal strains namely,Aspergillus niger and Aspergillus flavus. | Jayant Sindhu Harjinder Singh J.M.Khurana Chetan Sharma K.R.Aneja | 2015 | Chinese Chemical Letters2015，26，1： | 1 |
| 2 | An environmental friendly approach for the catalyst-free synthesis of highly substituted pyrazoles promoted by ultrasonic radiation显示文摘A cost-effective, highly useful and eco-friendly procedure for the one-pot synthesis of highly substituted pyrazole derivatives has been developed via the reaction of various aldehydes, malononitrile and phenylhydrazine or 4-phenylthiosemicarbazide in PEG-400 and water at room temperature under ultrasound irradiation. Utilization of green solvents without a catalyst makes this methodology very interesting from economic and environmental perspectives. This method provides several advantages such as operational simplicity, use of accessible and economical starting materials and reduced environmental consequences. | Firouzeh Nemati Seyed Hasan Nikkhah Ali Elhampour | 2015 | Chinese Chemical Letters2015，26，11： | 0 |
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