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| 1 | All-fiberized and narrow-linewidth 5 kW power-level fiber amplifier based on a bidirectional pumping configuration显示文摘In this paper,an all-fiberized and narrow-linewidth 5 kW power-level fiber amplifier is presented.The laser is achieved based on the master oscillator power amplification configuration,in which the phase-modulated single-frequency laser is applied as the seed laser and a bidirectional pumping configuration is applied in the power amplifier.The stimulated Brillouin scattering,stimulated Raman scattering,and transverse mode instability effects are all effectively suppressed in the experiment.Consequently,the output power is scaled up to 4.92 kW with a slope efficiency of as high as approximately 80%.The 3-dB spectral width is about 0.59 nm,and the beam quality is measured to be M^(2)~1.22 at maximum output power.Furthermore,we have also conducted a detailed spectral analysis on the spectral width of the signal laser,which reveals that the spectral wing broadening phenomenon could lead to the obvious decrease of the spectral purity at certain output power.Overall,this work could provide a reference for obtaining and optimizing high-power narrow-linewidth fiber lasers. | Pengfei Ma Hu Xiao Wei Liu Hanwei Zhang Xiaolin Wang Jinyong Leng Pu Zhou | 2021 | High Power Laser Science and Engineering2021，9，3： | 9 |
| 2 | The calcium-dependent protein kinase ZmCDPK7 functions in heat-stress tolerance in maize显示文摘Global warming poses a serious threat to crops.Calcium-dependent protein kinases(CDPKs)/CPKs play vital roles in plant stress responses,but their exact roles in plant thermotolerance remains elusive.Here,we explored the roles of heat-induced ZmCDPK7 in thermotolerance in maize.ZmCDPK7-overexpressing maize plants displayed higher thermotolerance,photosynthetic rates,and antioxidant enzyme activity but lower H2 O2 and malondialdehyde(MDA)contents than wild-type plants under heat stress.ZmCDPK7-knockdown plants displayed the opposite patterns.ZmCDPK7 is attached to the plasma membrane but can translocate to the cytosol under heat stress.ZmCDPK7 interacts with the small heat shock protein sHSP17.4,phosphorylates sHSP17.4 at Ser-44 and the respiratory burst oxidase homolog RBOHB at Ser-99,and up regulates their expression.Site-directed mutagenesis of sHSP17.4 to generate a Ser-44-Ala substitution reduced ZmCDPK7’s enhancement of catalase activity but enhanced ZmCDPK7’s suppression of MDA accumulation in heat-stressed maize protoplasts.sHSP17.4,ZmCDPK7,and RBOHB were less strongly upregulated in response to heat stress in the abscisic acid-deficient mutant vp5 versus the wild type.Pretreatment with an RBOH inhibitor suppressed sHSP17.4 and ZmCDPK7 expression.Therefore,abscisic acid-induced ZmCDPK7 functions both upstream and downstream of RBOH and participates in thermotolerance in maize by mediating the phosphorylation of sHSP17.4,which might be essential for its chaperone function. | Yulong Zhao Hanwei Du Yankai Wang Huali Wang Shaoyu Yang Chaohai Li Ning Chen Hao Yang Yihao Zhang Yulin Zhu Luyao Yang Xiuli Hu | 2021 | Journal of Integrative Plant Biology2021，63，3： | 6 |
| 3 | Novel constant-cladding tapered-core ytterbium-doped fiber for high-power fiber laser oscillator显示文摘Power scaling based on traditional ytterbium-doped fibers(YDFs)is limited by optical nonlinear effects and transverse mode instability(TMI)in high-power fiber lasers.Here,we propose a novel long tapered fiber with a constant cladding and tapered core(CCTC)along its axis direction.The tapered-core region of the fiber is designed to enhance the stimulated Raman scattering(SRS)threshold and suppress higher-order mode resonance in the laser cavity.The CCTC YDF was fabricated successfully with a modified chemical vapor deposition(MCVD)method combined with solution doping technology,which has a cladding diameter of 400µm and a varying core with a diameter of~24μm at both ends and~31μm in the middle.To test the performance of the CCTC fiber during high-power operation,an all-fiber laser oscillator based on a CCTC YDF was investigated experimentally.As a result,a maximum output power of 3.42 kW was achieved with an optical-to-optical efficiency of 55.2%,although the TMI effect was observed at an output power of~3.12 kW.The measured beam quality(M^(2)factor)was~1.7,and no sign of the Raman component was observed in the spectrum.We believe that CCTC YDF has great potential to simultaneously mitigate the SRS and TMI effects,and further power scaling is promising by optimizing the structure of the YDF. | Yun Ye Xianfeng Lin Xiaoming Xi Chen Shi Baolai Yang Hanwei Zhang Xiaolin Wang Jinyan Li Xiaojun Xu | 2021 | High Power Laser Science and Engineering2021，9，2： | 5 |
| 4 | kW-class high power fiber laser enabled by active long tapered fiber显示文摘Compared with traditional uniform fibers, tapered fiber has numerous unique advantages, such as larger mode area,higher pump absorption, suppression to nonlinear effects, and maintaining good beam quality. In this manuscript, we have constructed an all-fiberized fiber amplifier which is based on a piece of ytterbium-doped tapered double-clad fiber(T-DCF). The fiber amplifier is operated under continuous wave(CW) regime at 1080 nm wavelength. The M2 factor of the amplifier at 1.39 k W output power is ~1.8. The maximum output power of the system reached 1.47 k W, which, to the best of our knowledge, is the highest output power of long tapered fiber based fiber laser system. Our result successfully verifies the potential of power scalability and all-fiberized capability of long tapered fiber, and the performance of our system can be further enhanced by fiber design optimization. | Chen Shi Hanwei Zhang Xiaolin Wang Pu Zhou Xiaojun Xu | 2018 | High Power Laser Science and Engineering2018，6，2： | 4 |
| 5 | Investigation on random distributed feedback Raman fiber laser with linear polarized output显示文摘A random distributed feedback fiber laser with linear polarized output at 1178 nm is presented. Linear polarization is realized by fiber coiling in a half-opened cavity of a polarization maintaining random fiber laser structure.The single linear polarization laser output power reaches ~3 W with polarization extinction ratio >14 dB. Further investigations on the coiling technique and additional feedback are also studied. So far as we know, this is the first reported linear polarized random distributed feedback Raman fiber laser. | Xueyuan Du Hanwei Zhang Xiaolin Wang Pu Zhou Zejin Liu | 2015 | Photonics Research2015，3，2： | 3 |
| 6 | Phase segregation in inorganic mixed-halide perovskites:from phenomena to mechanisms显示文摘Halide perovskites,such as methylammonium lead halide perovskites(MAPbX3,X=I,Br,and Cl),are emerging as promising candidates for a wide range of optoelectronic applications,including solar cells,light-emitting diodes,and photodetectors,due to their superior optoelectronic properties.All-inorganic lead halide perovskites CsPbX3 are attracting a lot of attention because replacing the organic cations with Cs+enhances the stability,and its halide-mixing derivatives offer broad bandgap tunability covering nearly the entire visible spectrum.However,there is evidence suggesting that the optical properties of mixed-halide perovskites are influenced by phase segregation under external stimuli,especially illumination,which may negatively impact the performance of optoelectronic devices.It is reported that the mixed-halide perovskites in forms of thin films and nanocrystals are segregated into a low-bandgap I-rich phase and a high-bandgap Br-rich phase.Herein,we present a critical review on the synthesis and basic properties of all-inorganic perovskites,phase-segregation phenomena,plausible mechanisms,and methods to mitigate phase segregation,providing insights on advancing mixed-halide perovskite optoelectronics with reliable performance. | Yutao Wang Xavier Quintana Jiyun Kim Xinwei Guan Long Hu Chun-Ho Lin Brendon Tyler Jones Weijian Chen Xiaoming Wen Hanwei Gao Tom Wu | 2020 | Photonics Research2020，8，11： | 3 |
| 7 | Meiotic Chromosome Behavior in a Human Male t(8;15)Carrier显示文摘Reciprocal translocation is one of the most common structural chromosomal rearrangements in human beings;it is widely recognized to be associated with male infertility.This association is mainly based on the abnormal chromosome behavior of the translocated chromosomes and sex chromosomes during meiosis prophase I in reciprocal translocation carriers.However,the underlying mechanisms are not completely known.Here we report a reciprocal translocation carrier of t(8;15),who is oligozoospermic due to apoptosis of primary spermatocytes and to premature germ cell desquamation from seminiferous tubules.Further analysis showed abnormal synapsis and recombination frequency in this patient,indicating a connection between chromosome behavior and apoptosis of primary spermatocytes.We also compared these observations with recently reported findings on spermatogenesis defects in reciprocal translocation carriers,and discuss the possible mechanisms underlying bom common and unique phenotypes of reciprocal translocations involving different chromosomes with the aim of further understanding the regulation of human spermatogenesis. | Hanwei Jiang Liu Wang Yingxia Cui Zhipeng Xu Tonghang Guo Dongkai Cheng Peng Xu Wen Yu Qinghua Shi | 2014 | Journal of Genetics and Genomics2014，41，3： | 2 |
| 8 | Preparation of PVA/ Chitosan Lipase Membrane Reactor and its Application in Synthesis of Monoglyceride 显示文摘 | Hanwei Tan Fang Wang Hua Zhang | 2002 | Journal of Molecular Catalysis2002，，： | 1 |
| 9 | Preparation and drug release behaviors of 5-fluorouracil loaded poly(glycolide-co-lactide- co-caprolactone) nanoparticles显示文摘 | Hanwei Zhang Jianzhong Bei Shenguo Wang | 2007 | J Appl Polym Sci2007，106，6： | 1 |
| 10 | 100 W-level Tm-doped fiber laser pumped by 1173 nm Raman fiber lasers显示文摘 | Wang Xiong Zhou Pu Zhang Hanwei | 2014 | Optics Letters2014，39，15： | 1 |
| 11 | Effective inhibition of mRNA accumulation and protein expression of H5N1 avian influenza virus NS1 gene in vitro by small interfering RNAs显示文摘 | Hanwei Jiao Li Du Yongchang Hao Ying Cheng Jing Luo Wenhua Kuang Donglin Zhang Ming Lei Xiaoxiao Jia Xiaoru Zhang Chao Qi Hongxuan He Fengyang Wang | 2013 | Folia Microbiologica2013，，4： | 1 |
| 12 | Toward high-power nonlinear fiber amplifier显示文摘Stimulated Raman scattering(SRS) effect is considered to be one of the main obstacles for power scaling in general-type fiber lasers. Different from previous techniques that aim at suppressing SRS, nonlinear fiber amplifier(NFA), which manipulates and employs the SRS for power scaling in rare-earth-doped fiber, is under intensive research in recent years.In this paper, the authors will present an all-round study on this new kind of high-power fiber amplifier. A theoretical model is proposed based on the rate equation and amplified spontaneous emission(ASE), with random noise taken into account. By numerical solving of the theoretical model, the power scaling potential, heat analysis and advantages in suppressing the undesired backscattering light are quantificationally analyzed for the first time. Then two different types of high-power NFAs are demonstrated individually. Firstly, a laser diode pumped NFA has reached kilowatt output power,and the results agree well with theoretical predictions. Secondly, a tandem-pumped NFA is proposed for the first time and validated experimentally, in which 1.5 kW output power has been achieved. The authors also briefly discuss several new issues relating to the complex nonlinear dynamics that occur in high-power NFAs, which might be interesting topics for future endeavors. | Hanwei Zhang Pu Zhou Hu Xiao Jinyong Leng Rumao Tao Xiaolin Wang Jiangming Xu Xiaojun Xu Zejin Liu | 2018 | High Power Laser Science and Engineering2018，6，3： | 1 |
| 13 | Broad-spectrum and powerful neutralization of bacterial toxins by erythroliposomes with the help of macrophage uptake and degradation显示文摘Anti virulence strategy has been considered as one of the most promising approaches to combat drug-rcesistant bacterial infections.Porc-forming toxins(PFTs)are the largest class of bacterial toxins,inficting their virulence ffect through creating pores on the cell membrane.However,curent solutions for eliminating PFTs are mostly designed based on their molecular structure,requiring customized design for different interactions.In the present study,we employed erythroliposome(denoted as RM-PL),a biomimetic platform constructed by artificial lipid membranes and natural erythrocyle membranes,to necutralize different hemolytic PFTs regardless of their molecular structure.When tested with model PFTs,including a-hemolysin,listeriolysin O,and streptolysin O,RM-PL could completely inhibit toxin-induced hemolysis in a concentration-dependent manner.In vivo studies further confirmed that RM-PL.could eficiently neuralize various toxins and save animals'lives without causing damage to 0rgans or tissues.In addition,we explored the underlying mechanisms of this efficient detoxification ability and found that it was mainly macrophages in the spleen and the liver that took up RM-PL-absorbed toxins through a variety of endocytosis pathways and digested them in lysosomes.In summary,the biomimetic RM-PL presented a promising system for broad-spectrum and powerful toxin neutralization with a mech-anism of lysosome-mediaed loxin degradation. | Chunying Liu Shuangrong Ruan Ying He Xuejing Li Yuefei Zhu Honglan Wang Hanwei Huang Zhiqing Pang | 2022 | Acta Pharmaceutica Sinica B2022，12，11： | 1 |
| 14 | A 3.5-kW near-single-mode oscillating-amplifying integrated fiber laser显示文摘The fiber laser based on an oscillating-amplifying integrated structure has the potential to benefit from the advantages of a fiber laser oscillator and amplifier with the characteristics of strong anti-back-reflected light ability and high efficiency.Here,we achieved a 3.5-kW near-single-mode(M^(2)~1.24)oscillating-amplifying integrated fiber laser with an active fiber length of 8 m in the oscillating section and 17.6 m in the amplifying section.While operating at the maximum power,the optical-to-optical conversion efficiency is 87.0%,and the intensity of stimulated Raman scattering is about23.61 dB lower than that of the signal light.To the best of the authors’knowledge,this is the highest output power of an oscillating-amplifying integrated fiber laser,accompanied with the best beam quality and the highest efficiency. | Lingfa Zeng Xiaolin Wang Baolai Yang Hanwei Zhang Xiaojun Xu | 2021 | High Power Laser Science and Engineering2021，9，3： | 1 |
| 15 | Monolayer tungsten disulfide in photonic environment:Angleresolved weak and strong light-matter coupling显示文摘Light-matter interactions in two-dimensional transition metal dichalcogenides(TMDs)are sensitive to the surrounding dielectric environment.Depending on the interacting strength,weak and strong exciton–photon coupling effects can occur when the exciton energy is resonant with the one of photon.Here we report angle-resolved spectroscopic signatures of monolayer tungsten disulfide(1L-WS2)in weak and strong exciton–photon coupling environments.Inherent optical response of 1L-WS_(2)in the momentum space is uncovered by employing a dielectric mirror as substrate,where the energy dispersion is angleindependent while the amplitudes increase at high detection angles.When 1L-WS_(2)sits on top of a dielectric layer on silicon,the resonant trapped photon weakly couples with the exciton,in which the minimum of reflection dip shifts at both sides of the crossing angle while the emitted exciton energy remains unchanged.The unusual shift of reflection dip is attributed to the presence of Fano resonance under white-light illumination.By embedding 1L-WS_(2)into a dielectric microcavity,strong exciton–photon coupling results in the formation of lower and upper polariton branches with an appreciable Rabi splitting of 34 meV at room temperature,where the observed blueshift of the lower polariton branch is indicative of the enhanced polaritonpolariton scattering.Our findings highlight the effect of dielectric environment on angle-resolved optical response of exciton–photon interactions in a two-dimensional semiconductor,which is helpful to develop practical TMD-based architectures for photonic and polaritonic applications. | Xuewen Zhang Lishu Wu Xu Wang Silin He Hanwei Hu Guangchao Shi Xingwang Zhang Jingzhi Shang Ting Yu | 2022 | Nano Research2022，15，6： | 1 |
| 16 | Correlation of coordinate transformation parameters显示文摘Coordinate transformation parameters between two spatial Cartesian coordinate systems can be solved from the positions of non-colinear corresponding points.Based on the characteristics of translation,rotation and zoom components of the transformation,the complete solution is divided into three steps.Firstly,positional vectors are regulated with respect to the centroid of sets of points in order to separate the translation components.Secondly,the scale coefficient and rotation matrix are derived from the regulated positions independently and correlations among transformation model parameters are analyzed.It is indicated that this method is applicable to other sets of non-position data to separate the respective attributions for transformation parameters. | Du Lan Zhang Hanwei Zhou Qingyong Wang Ruopu | 2012 | Geodesy and Geodynamics2012，3，1： | 1 |
| 17 | Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling显示文摘 | Junfang Zhang Hailong Cao Bing Zhang Hanwei Cao Xiuqin Xu Hang Ruan Tingting Yi Li Tan Rui Qu Gang Song Bangmao Wang Tianhui Hu | 2013 | J. Cell. Mol. Med2013，，11： | 1 |
| 18 | Chirality Enhancement Using Fabry-Pérot-Like Cavity显示文摘Chiral molecules that do not superimpose on their mirror images are the foundation of all life forms on earth.Chiral molecules exhibit chiroptical responses,i.e.,they have different electromagnetic responses to light of different circular polarizations.However,chiroptical responses in natural materials,such as circular dichroism and optical rotation dispersion,are intrinsically small because the size of a chiral molecule is significantly shorter than the wavelength of electromagnetic wave.Conventional technology for enhancing chiroptical signal entails demanding requirements on precise alignment of the chiral molecules to certain nanostructures,which however only leads to a limited performance.Herein,we show a new approach towards enhancement of chiroptical effects through a Fabry-Pérot(FP)cavity formed by two handedness-preserving metamirrors operating in the GHz region.We experimentally show that the FP cavity resonator can enhance the optical activity of the chiral molecule by an order of magnitude.Our approach may pave the way towards state-of-the-art chiral sensing applications. | Jiaxin Bao Ning Liu Hanwei Tian Qiang Wang Tiejun Cui Weixiang Jiang Shuang Zhang Tun Cao | 2020 | Research2020，，1： | 1 |
| 19 | Characterization of uncommon portosystemic collateral circulations inpatients with hepatic cirrhosis显示文摘 | Qin Wu Lijun Shen Jindong Chu Xuemei Ma Bo Jin Fanping Meng Jinpin Chen Yanling Wang Libing Wu Jun Han Wenhui Zhang Wei Ma Huaming Wang Hanwei Li | 2015 | Oncology Letters2015，，1： | 1 |
| 20 | Research on tension control model for traction and take-up system of loom显示文摘 | WANG Youzhao HUANG Jing CHEN Hanwei | 2013 | Advanced Materials Research2013，627，： | 1 |
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