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| 1 | Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats显示文摘AIM: To evaluate the role of reactive oxygen species in the pathogenesis of acute ethanol-induced gastric mucosal lesions and the effect of Nigella sativa L oil (NS) and its constituent thymoquinone (TQ) in an experimental model.METHODS: Male Wistar albino rats were assigned into 4groups. Control group was given physiologic saline orally (10 mL/kg body weight) as the vehicle (gavage); ethanol group was administrated 1 mL (per rat) absolute alcohol by gavage; the third and fourth groups were given NS (10 mL/kg body weight) and TQ (10 mg/kg body weight p.o) respectively 1 h prior to alcohol intake. One hour after ethanol administration, stomach tissues were excised for macroscopic examination and biochemical analysis.RESULTS: NS and TQ could protect gastric mucosa against the injurious effect of absolute alcohol and promote ulcer healing as evidenced from the ulcer index (UI) values. NS prevented alcohol-induced increase in thiobarbituric acid-reactive substances (TBARS), an index of lipid peroxidation. NS also increased gastric glutathione content (GSH), enzymatic activities of gastric superoxide dismutase (SOD) and glutathione-S-transferase (GST). Likewise, TQ protected against the ulcerating effect of alcohol and mitigated most of the biochemical adverse effects induced by alcohol in gastric mucosa, but to a lesser extent than NS. Neither NS nor TQ affected catalase activity in gastric tissue.CONCLUSION: Both NS and TQ, particularly NS can partly protect gastric mucosa from acute alcohol-induced mucosal injury, and these gastroprotective effects might be induced, at least partly by their radical scavenging activity. | Mehmet Kanter Halit Demir Cengiz Karakaya Hanefi Ozbek | 2005 | World Journal of Gastroenterology2005，11，42： | 9 |
| 2 | Overview of neurobrucellosis: a pooled analysis of 187 cases显示文摘 | Hanefi Cem Gul Hakan Erdem Semai Bek | 2009 | International Journal of Infectious Diseases2009，，6： | 2 |
| 3 | Axial resistance and en- ergy absorption of externally reinforced metal tubes 显示文摘 | HANEFI E H WIERZBICKI T | 1996 | Composites: Part B1996，27，5： | 1 |
| 4 | Direct pelvic access percuta- neous nephrolithotomy in management of ectopic kidney stone : A case report and literature review显示文摘 | Mehmet RM Rustu YF Hanefi B | 2013 | Renal Failure2013，35，10： | 1 |
| 5 | Direct pelvic access percutaneous nephrolithotomy in management of ectopic kidney stone:a case report and literature review显示文摘 | Mehmet RM Rustu YF Hanefi B | 2013 | Ren Fail2013，35，10： | 1 |
| 6 | Investigation of Hepatoprotective Effect of Foeniculum vulgate Fixed Oil in Rats 显示文摘 | Hanefi Ozbek Irfan Bayram scrdar Ugras | 2006 | Research Journal of Medicine and Medical Sciences2006，1，2： | 1 |
| 7 | Direct pelvic access pereutaneous nephrolithotomy in management of ectopic kidney stone: a case report and literature review显示文摘 | Mehmet RM Rustu YF Hanefi B | 2013 | Ren Fail2013，35，10： | 1 |
| 8 | Overview of neuro-brucellosis:a pooled analysis of 187 cases显示文摘 | Hanefi Cem Gul Hakan Erdem Semai Bek | | 0，，06： | 1 |
| 9 | Direct pelvicaccess percutaneous nephrolithotomy in management of ectopic kidney stone:a case report and literature review显示文摘 | Mehmet RM Rustu YF Hanefi B | | 0，，10： | 1 |
| 10 | First molecular characterization of a Turkish orf virus strain from a human based on a partial B2L sequence显示文摘 | Ahmet Karakas Tuba Cigdem Oguzoglu Omer Coskun Cumhur Artuk Gurkan Mert Hanefi Cem Gul Kenan Sener Aykut ?zkul | 2013 | Archives of Virology2013，，5： | 1 |
| 11 | A Kriging-based approach for locating a sampling site—in the assessment of air quality显示文摘 | Hanefi Bayraktar F. Sezer. Turalioglu | 2005 | Stochastic Environmental Research and Risk Assessment2005，，4： | 1 |
| 12 | Axial resistance and energy absorption of externally reinforced metal tubes显示文摘 | HANEFI E H WIERZBICKI T | 1996 | Composite Part B1996，27，： | 1 |
| 13 | The July 15 Coup Attempt in Turkey and the Hypocricy of the West显示文摘 | Hanefi YaZiCi | 2016 | China-USA Business Review2016，15，11： | 0 |
| 14 | Hippocampus and amygdala volumes in patients with vaginismus显示文摘AIM: To compare hippocampus and amygdala volumes of patients with vaginismus with those of healthy control subjects.METHODS: Magnetic resonance imaging was performed on ten patients with vaginismus and ten control subjects matched for age and gender. Volumes of the hippocampus and amygdala were blindly measured. RESULTS: We found that the mean right amygdala volume of patients with vaginismus were smaller than that of the healthy controls. With regard to hippocampus volumes, the mean left and right hippocampus volumes were smaller than those of the healthy controls. CONCLUSION: Our present findings suggest that there have been hippocampus and amygdala structural abnormalities in patients with vaginismus. These changes provide the notion that vaginismus may be a fear-related condition. | Murad Atmaca Sema Baykara Omer Ozer Sevda Korkmaz Unsal Akaslan Hanefi Yildirim | 2016 | World Journal of Psychiatry2016，6，2： | 0 |
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