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| 1 | Shugan Huoxue Huayu Fang(疏肝活血化瘀方)attenuates carbon tetrachloride-induced hepatic fibrosis in rats by inhibiting transforming growth factor-β1/Smad signaling显示文摘OBJECTIVE:To investigate the potential mechanism by which Shugan Huoxue Huayu Fang(疏肝活血化瘀方,SGHXHYF)ameliorates liver fibrosis.METHODS:Liver fibrosis was induced in rats by intraperitoneal injection of carbon tetrachloride(CCl_(4))in peanut oil solution(40%,3 m L/kg body weight)twice a week for 8 weeks.A normal control group received the same volume of peanut oil alone.During weeks 5-8,the CCl_(4)-injected rat groups were administered saline(vehicle control),colchicine(0.1 mg/mL,1 mg/kg,positive control),or SGHXHYF(0.1 mg/mL;0.3,0.6 and 1.2 mg/kg)once daily by oral gavage.Rats were sacrificed 24 h after the last treatment.Blood samples were collected for measurement of serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP),albumin(ALB),collagenⅠ,and collagenⅢlevels.Liver samples were analyzed by histopathological staining,Masson's staining of extracellular matrix proteins,and immune-ohistochemical staining ofα-smooth muscle actin(α-SMA).TGF-β1/Smad protein and mRNA levels were analyzed by Western blot and quantitative reverse transcription-polymerase chain reaction analysis,respectively.In vitro experiments were also performed using rat hepatic stellate cells(HSCs).RESULTS:Compared with the control animals,CCl_(4)-exposed rats exhibited elevated serum levels of ALT,AST,ALP,collagenⅠ,and collagenⅢ;reduced serum levels of ALB;and increased collagen deposition andα-SMA expression in liver sections,reflecting liver fibrosis.CCl_(4) also increased expression of TGF-β1 and the activated(phosphorylated)forms of Smad2 and Smad3 but reduced expression of the negative regulator Smad7 in the liver.Notably,concomitant administration of SGHXHYF to CCl_(4)-exposed rats was found to significantly reverse or abolish the pro-fibrotic effects of CCl_(4) in the liver and reduced serum transferase levels.Analysis of HSCs in vitro confirmed that,mechanistically,SGHXHYF inhibited activation of the TGF-β1/Smad signaling pathway by downregulating phosphorylated Smad2 and Smad3 and upregulating Smad7 levels.CONCLUSION:SGHXHYF ameliorated CCl_(4)-induced liver fibrosis by inhibiting the TGF-β1/Smad signaling pathway.These findings suggest that SGHXHYF may have clinical utility for the treatment or prevention of liver fibrosis. | LIU Lei GUO Hanbin SHAO Cuiping WANG Lin XU Youqing ZHOU Yiming | 2022 | Journal of Traditional Chinese Medicine2022，42，1： | 2 |
| 2 | 中国大鲵隐存种及其灭绝危机显示文摘文章简介由于栖息地破坏及人为过度捕捉,中国大鲵的野生资源锐减。由于缺乏显著的外部性状差异,中国大鲵长期以来被认为是一个物种。不同地方的种群是否存在显著的分化?目前基于'一个物种'的保护策略是否得当. | 颜芳 Jingcai Lü Baolin Zhang Zhiyong Yuan Haipeng Zhao Song Huang Gang Wei Xue Mi Dahu Zou Wei Xu Shu Chen Jie Wang Feng Xie Minyao Wu Hanbin Xiao Zhiqiang Liang Jieqiong Jin Shifang Wu CunShuan Xu Benjamin Tapley Samuel T.Turvey Theodore J.Papenfuss Andrew A.Cunningham Robert W.Murphy 张亚平 车静 | 2019 | 科学新闻2019，0，2： | 1 |
| 3 | Long-Term Temperature Variability and Risk of Dyslipidemia Among Middle-Aged and Elderly Adults:A Prospective Cohort Study-China,2011-2018显示文摘Summary What is already known about this topic?Long-term temperature variability(TV)has been examined to be associated with cardiovascular disease(CVD).TV-related dyslipidemia helps us understand the mechanism of how climate change affects CVD.What is added by this report?Based on the China Health and Retirement Longitudinal Study(CHARLS)from 2011 to 2018,this study estimated the long-term effect of TV on dyslipidemia in middle-aged and elderly adults. | Jianbo Jin Yuxin Wang Zhihu Xu Ru Cao Hanbin Zhang Qiang Zeng Xiaochuan Pan Jing Huang Guoxing Li | 2022 | China CDC weekly2022，4，26： | 1 |
| 4 | Microstructure and Properties of Spray Formed Crl2MoV Steel for Rolls显示文摘 | Zhang Jingguo Xu Hanbin Shi Haisheng | 2001 | Journal of Materials Processing Technology2001，111，： | 1 |
| 5 | Maternal Preconception Serum Alanine Aminotransferase Levels and Risk of Preterm Birth among Reproductive-Aged Women—China,2013-2017显示文摘Summary What is already known about this topic?The significance of maternal liver health concerning preterm birth(PTB)is well recognized;however,there is a gap in understanding the precise influence of preconception serum alanine aminotransferase(ALT)levels on the risk of PTB.What is added by this report? | Chuanyu Zhao Jiajing Jia Hanbin Wu Qin Xu Xinyi Lyu Meiya Liu Xuan Hu Jueming Lei Yuzhi Deng Yuan He Yuanyuan Wang Zuoqi Peng Ya Zhang Hongguang Zhang Qiaomei Wang Haiping Shen Yiping Zhang Donghai Yan Ying Yang Xu Ma | 2024 | China CDC weekly2024，6，10： | 0 |
| 6 | Flexural and longitudinal shear performance of precast lightweight steel-ultra-high performance concrete composite beam显示文摘In this study,the flexural and longitudinal shear performances of two types of precast lightweight steel–ultra-high performance concrete(UHPC)composite beams are investigated,where a cluster UHPC slab(CUS)and a normal UHPC slab(NUS)are connected to a steel beam using headed studs through discontinuous shear pockets and full-length shear pockets,respectively.Results show that the longitudinal shear force of the CUS is greater than that of the NUS,whereas the interfacial slip of the former is smaller.Owing to its better integrity,the CUS exhibits greater flexural stiffness and a higher ultimate bearing capacity than the NUS.To further optimize the design parameters of the CUS,a parametric study is conducted to investigate their effects on the flexural and longitudinal shear performances.The square shear pocket is shown to be more applicable for the CUS,as the optimal spacing between two shear pockets is 650 mm.Moreover,a design method for transverse reinforcement is proposed;the transverse reinforcement is used to withstand the splitting force caused by studs in the shear pocket and prevent the UHPC slab from cracking.According to calculation results,the transverse reinforcement can be canceled when the compressive strength of UHPC is 150 MPa and the volume fraction of steel fiber exceeds 2.0%. | Ze MO Jiangrui QIU Hanbin XU Lanlan XU Yuqing HU | 2023 | Frontiers of Structural and Civil Engineering2023，17，5： | 0 |
| 7 | Promoting Proton Migration Kinetics by Ni^(2+)Regulating Enables Improved Aqueous Zn-MnO_(2) Batteries显示文摘The energy storage behaviors of MnO_(2) for aqueous Zn-MnO_(2) batteries mainly depend on the Zn^(2+)/H^(+)intercalation but are limited by poor ion/electron migration dynamics and stability.Herein,a strategy is proposed that promoting proton migration kinetics ameliorates H^(+)storage activity by introducing Ni^(2+)intoγ-MnO_(2)(Ni-MnO_(2)).Ni^(2+)can lower the diffusion barrier of H^(+)and selectively induce the ion intercalation,thereby alleviating the electrostatic interaction with the lattice.Moreover,Ni^(2+)enables the adjacent[MnO6]octahedrons to have better electron conductivity.The Ni-MnO_(2) exhibits superior rate performance(nearly four times specific capacity compared with MnO_(2))and ultra-long-cycle stability(100%of capacity retention after 11000 cycles at 3.0 A g^(-1)).The calculation indicates that the Ni-MnO_(2) allows H^(+)migrate rapidly along the one-dimensional tunnel due to reduction of the activation energy caused by Ni^(2+)regulating,thus achieving excellent reaction kinetics.This work brings great potential for the development of high-performance aqueous Zn-MnO_(2) batteries. | Jie Ji Jia Yao Yongchang Xu Houzhao Wan Bao Zhang Lin Lv Jingying Li Nengze Wang Zhaohan Zheng Jun Zhang Guokun Ma Li Tao Hanbin Wang Yi Wang Hao Wang | 2023 | Energy & Environmental Materials2023，6，2： | 0 |
| 8 | Ultrasensitive,flexible perovskite nanowire photodetectors with long-term stability exceeding 5000 h显示文摘Photodetectors(PDs)based on perovskite nanowires are among the most promising next-generation photodetection technologies;however,their poor long-term stability is the biggest challenge limiting their commercial applica-tion.Herein,an ionic liquid,1-butyl-3 methylimidazolium tetrafuoroborate(BMIMBF_(4)),is incorporated as an additive into methylammonium lead tri-iodide(MAPbI_(3))nanowires;this not only effectively passivates defects to inhibit perovskite degradation but also leads to the formation of nanochannels,enabling fast charge transfer.As a result,the long-term stability and perfor-mance of MAPbI_(3)nanowires are considerably improved.The detectivity,linear detection range,and noise equivalent power of the MA PbI_(3)nanowire PD reach 2.06×10^(13)Jones,160dB,and 1.38×10^(-15)W Hz-^(1/2),respectively,compara-ble to the highest performance of perovskite nanowire PDs reported to date.Moreover,the unencapsulated PD can maintain 100%of its initial performance after being exposed to an open-air environment for more than 5000 h,esta-blishing it as the most stable perovskite nanowire PD reported to date.Nota-bly,the PD exhibits improved diffuse reflection imaging ability when compared with commercial silicon photodiode S2386.This study provides a new strategy for constructing sensitive,stable,and flexible perovskite PDs and will accelerate their commercial application in the future. | Dingjun Wu Yongchang Xu Hai Zhou Xin Feng Jianqiang Zhang Xiyan Pan Zheng Gao Rui Wang Guokun Ma Li Tao Hanbin Wang Jinxia Duan Houzhao Wan Jun Zhang Liangping Shen Hao Wang Tianyou Zhai | 2022 | InfoMat2022，4，9： | 0 |
| 9 | Favorable anion adsorption/desorption of high rate NiSe_(2) nanosheets/hollow mesoporous carbon for battery-supercapacitor hybrid devices显示文摘High-rate battery-type cathode materials have attracted wide attention for advanced battery-supercapacitor hybrid(BSH)devices.Herein,a core-shell structure of the hollow mesoporous carbon spheres(HMCS)supported NiSe2 nanosheets(HMCS/NiSe2)is constructed through two-step reactions.The HMCS/NiSe_(2)shows a max specific capacity of 1,153.5 C·g^(-1) at the current density of 1 A·g^(-1),and can remain at 774.5 C·g^(-1) even at 40 A·g^(-1)(the retention rate as high as 67.1%)and then the HMCS/NiSe_(2) electrode can keep 80.5%specific capacity after 5,000 cycles at a current density of 10 A·g^(-1).Moreover,the density functional theory(DFT)calculation confirmed that the introduction HMCS into NiSe_(2) made adsorption/desorption of OH-easier,which can achieve higher rate capability.The HMCS/NiSe_(2)//6 M KOH//HMCS hybrid device has energy density of 47.15 Wh·kg^(-1) and power density of 801.8 W·kg^(-1).This work provides a feasible electrode material with a high rate and its preparation method for high energy density and power density energy storage devices. | Xiaojuan Zhao Houzhao Wan Pei Liang Nengze Wang Cong Wang Yi Gan Xu Chen Qiuyang Tan Xiang Liu Jun Zhang Yi Wang Hanbin Wang Hao Wang | 2021 | Nano Research2021，14，8： | 0 |
| 10 | Adversarial attacks and defenses in physiological computing:a systematic review显示文摘Physiological computing uses human physiological data as system inputs in real time.It includes,or significantly overlaps with,brain-computer interfaces,affective computing,adaptive automation,health informatics,and physiological signal based biometrics.Physiological computing increases the communication bandwidth from the user to the computer,but is also subject to various types of adversarial attacks,in which the attacker deliberately manipulates the training and/or test examples to hijack the machine learning algorithm output,leading to possible user confusion,frustration,injury,or even death.However,the vulnerability of physiological computing systems has not been paid enough attention to,and there does not exist a comprehensive review on adversarial attacks to them.This study fills this gap,by providing a systematic review on the main research areas of physiological computing,different types of adversarial attacks and their applications to physiological computing,and the corresponding defense strategies.We hope this review will attract more research interests on the vulnerability of physiological computing systems,and more importantly,defense strategies to make them more secure. | Dongrui Wu Jiaxin Xu Weili Fang Yi Zhang Liuqing Yang Xiaodong Xu Hanbin Luo Xiang Yu | 2023 | National Science Open2023，2，1： | 0 |
| 11 | ASIAN ARCHITECTURE ARCHIVE CENTER显示文摘Profile:Asian Architectural Archives Center(AAAC)is renovated from an old building of Sipailou Cam-pus of Southeast University in 1930s,which is one of the bungalows nearby the old library.In this project,the main structure is strengthened and repaired,the interior is moderately renovated as well as the performance is improved to adapt to the function replacement of the archive center. | ZHANG Xu SHI Yonggao ZHOU Xiaodi HOU Hanbin CHANG Junfu ZHAO Xiaopeng XUE Liang | 2023 | Frontiers of Architectural Research2023，12，1： | 0 |
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