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268篇 您的检索式：作者名="Hamilton D C"

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	题名	作者	年代	出处	被引量
1	Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.	Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele	2009	World Journal of Gastroenterology2009，15，10：	20
2	C-2 neurec-tomy during atlantoaxial instrumented fusion in the elderly: patient satisfaction and surgical outcome 显示文摘	Hamilton D K Smith J S Sansur C A	2011	J Neurosurg Spine2011，15，1：	1
3	Evidence for a male-produced sex pheromone in the western flower thrips Frankliniella occidentals显示文摘	Kirk W D J Hamilton J G C		0，，01：	1
4	A species of small antisense RNA in post transcriptional gene silencing in plants显示文摘	HAMILTON A J BAULCOMBE D C	1999	Science1999，286，5441：	1
5	An investigation of the route and progression of encephalitozoon cuniculi infection in adult rabbits显示文摘	Cox J C Hamilton R C Attwood H D	1979	J Protozool1979，26，1：	1
6	Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘	Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R	2009	Journal of Bacteriology2009，191，16：	1
7	A species of small antisens RNA in post transcriptional gene silencing in plants显示文摘	Hamilton A J Baulcombe D C	1999	Science1999，286，5441：	1
8	A hospital randomized controlled trial of an educational quality improvement intervention in rural and small community hospitals in Texas following implementation of information technology显示文摘	Filardo G Nicewander D Hamilton C		0，，6：	1
9	A theory of lubrication by microirregulafities显示文摘	Hamilton D Walowit J Allen C	1966	Journal of Fluids Engineering1966，88，1：	1
10	A species of small antisense RNA in posttranscriptional gene silencing in plants显示文摘	BAULCOMBE D C	1999	Science1999，286，：	1
11	A theory of lubrication by micro-irregularities显示文摘	Hamilton D B Walawit J A Allen C M	1966	ASME Journal of Basie Engineering1966，88，1：	1
12	Optical sampling and demultiplexing applied to A/D conversion显示文摘	Hamilton M C Leep D A	1991	Proc SPIE1991，1562，：	1
13	Modelling the relative importance of internal and external nutrient loads on water column nutrient concentrations and phytoplankton biomass in a shallow polymictic lake 显示文摘	Burger D F Hamilton D P Pilditch C A	2008	Ecological Modelling2008，211，：	1
14	Patron-initiatedcollection development: progress of a paradigmshift显示文摘	Hodges D Preston C Hamilton M J	2010	Collection Management2010，35，34：	1
15	Simulation of vertical position of buoyancy regulating Microcystis aeruginosa in a shallow eutrophic lake 显示文摘	Wallace B B Bailey M C Hamilton D P	2000	Aquatic Science2000，62，：	1
16	Effect of ageing on CA3 interneuron sAHP and gamma oscillations is activity-dependent 显示文摘	Lu C B Hamilton J B Powell A D	2011	Neurobiol Aging2011，32，5：	1
17	The Effectiveness of Alternative Monetary Policy Tools in a Zero Lower Bound Environment 显示文摘	Hamilton J D Wu J C	2012	Journal of Money Credit and Banking2012，，：	1
18	A spatially resolved model of seasonal variations in phytoplankton and clam (Tapes philippinarum) biomass in Barbamarco Lagoon,Italy显示文摘	Spillman C M Hamilton D P Hipsey M R	2008	Estuarine Coastal and Shelf Science2008，79，2：	1
19	Patron-initiated collection development: Progress of a paradigm shift显示文摘	Hodges D Preston C Hamilton M J	2010	Collection Management2010，35，34：	1
20	A species of small antisense RNA in posttranscriptional gene silencing in plants 显示文摘	Hamilton A J Baulcombe D C	1999	Science1999，286，：	1

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