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| 1 | Enhancement of tumor‐associated antigen‐specific T cell responses by radiofrequency ablation of hepatocellular carcinoma显示文摘 | Eishiro Mizukoshi Tatsuya Yamashita Kuniaki Arai Hajime Sunagozaka Teruyuki Ueda Fumitaka Arihara Takashi Kagaya Taro Yamashita Kazumi Fushimi Shuichi Kaneko | 2013 | Hepatology2013，，4： | 2 |
| 2 | Colon cancer arising from colonic diverticulum:A case report显示文摘BACKGROUND Colonic diverticulosis is a common disease, and the coexistence of colonic diverticulosis and colorectal cancer is often seen clinically. It is very rare that colon cancer arises from the mucosa of a colonic diverticulum. When colon cancer arises in a diverticulum and then tends to develop outside the wall, without developing within the lumen, the differential diagnosis from complicating lesions due to colonic diverticulitis is difficult. CASE SUMMARY A 76-year-old man was admitted to a nearby clinic with a chief complaint of discomfort and urinary frequency. Since a vesicosigmoidal fistula was seen on abdominal computed tomography, he was referred to our hospital. Laparoscopic sigmoidectomy was performed because the various diagnostic findings were diagnosed as a vesicosigmoidal fistula with diverticulitis of the sigmoid colon. However, on histopathological examination, it was diagnosed as a vesicosigmoidal fistula due to colon cancer arising in the diverticulum. Laparoscopic partial resection of the bladder was performed because local recurrence was observed in the bladder wall one and a half years after surgery. It is currently one year after reoperation, but there has been no recurrence or metastasis. CONCLUSION Colon cancer arising in a diverticulum of the colon should be considered when diverticulitis with complications is observed. | Hajime Kayano Yusuhiko Ueda Takashi Machida Shinichiro Hiraiwa Hidenori Zakoji Takuma Tajiri Masaya Mukai Eiji Nomura | 2019 | World Journal of Clinical Cases2019，7，13： | 1 |
| 3 | Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance: Implications for type 2 diabetes显示文摘 | Yumie Takeshita Toshinari Takamura Yuki Kita Hitoshi Ando Teruyuki Ueda Kenichiro Kato Hirofumi Misu Hajime Sunagozaka Yoshio Sakai Tatsuya Yamashita Eishiro Mizukoshi Masao Honda Shuichi Kaneko | 2012 | Metabolism2012，，10： | 1 |
| 4 | Eye damage control by reduced blue illumination显示文摘 | Toshihiko Ueda Takako Nakanishi-Ueda Hajime Yasuhara Ryohei Koide William W. Dawson | 2009 | Experimental Eye Research2009，，6： | 1 |
| 5 | Thrombotic microangiopathy-like disorder after living-donor liver transplantation:A single-center experience in Japan显示文摘AIM:To investigate thrombotic microangiopathy (TMA)in liver transplantion,because TMA is an infrequent but life-threatening complication in the transplantation field. METHODS:A total of 206 patients who underwent living-donor liver transplantation (LDLT) were evaluated,and the TMA-like disorder (TMALD) occurred in seven recipients. RESULTS:These TMALD recipients showed poor outcomes in comparison with other 199 recipients. Although two TMALD recipients successfully recovered,the other five recipients finally died despite intensive treatments including repeated plasma exchange (PE) and re-transplantation. Histopathological analysis of liver biopsies after LDLT revealed obvious differences according to the outcomes. Qualitative analysis of antibodies against a disintegrin-like domain and metalloproteinase with thrombospondin type 1 motifs (ADAMTS-13) were negative in all patients. The fragmentation of red cells,the microhemorrhagic macules and the platelet counts were early markers for the suspicion of TMALD after LDLT. Although the absolute values of von Willebrand factor (vWF) and ADAMTS-13 did not necessarily reflect TMALD,the vWF/ADAMTS-13 ratio had a clear diagnostic value in all cases. The establishment of adequate treatments for TMALD,such as PE for ADAMTS-13 replenishment or treatments against inhibitory antibodies,must be decided according to each case. CONCLUSION:The optimal induction of adequate therapies based on early recognition of TMALD by the reliable markers may confer a large advantage for TMALD after LDLT. | Tomohide Hori Toshimi Kaido Fumitaka Oike Yasuhiro Ogura Kohei Ogawa Yukihide Yonekawa Koichiro Hata Yoshiya Kawaguchi Mikiko Ueda Akira Mori Yasutsugu Takada Hiroto Egawa Atsushi Yoshizawa Shinji Uemoto Hajime Segawa Kimiko Yurugi Takuma Kato Kanako Saito Linan Wan Mie Torii Feng Chen Ann-Marie T Baine Lindsay B Gardner | 2011 | World Journal of Gastroenterology2011，17，14： | 1 |
| 6 | Gene expression profiling of hepatitis B- and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling显示文摘 | Teruyuki Ueda Masao Honda Katsuhisa Horimoto Sachiyo Aburatani Shigeru Saito Taro Yamashita Yoshio Sakai Mikiko Nakamura Hajime Takatori Hajime Sunagozaka Shuichi Kaneko | 2013 | Genomics2013，，4： | 1 |
| 7 | Baicalin induces apoptosis via mitochondrial pathway as prooxidant显示文摘 | Shugo Ueda Hajime Nakamura Hiroshi Masutani Tetsuro Sasada Arimichi Takabayashi Yoshio Yamaoka Junji Yodoi | 2002 | Molecular Immunology2002，，10： | 1 |
| 8 | Effect of Sr addition to La-based perovskite-type oxide as an electrode material for zirconia-based amperometric-type NOx sensor显示文摘 | Taro Ueda Mitsunori Umeda Hajime Okawa Seiji Takahashi | 2012 | Ionics2012，，4： | 1 |
| 9 | Spotty Calcification Typifies the Culprit Plaque in Patients With Acute Myocardial Infarction: An Intravascular Ultrasound Study显示文摘 | Shoichi Ehara Yoshiki Kobayashi Minoru Yoshiyama Kenei Shimada Yoshihisa Shimada Daiju Fukuda Yasuhiro Nakamura Hajime Yamashita Hiroyuki Yamagishi Kazuhide Takeuchi Takahiko Naruko Kazuo Haze Anton E. Becker Junichi Yoshikawa Makiko Ueda | 2004 | Circulation2004，，22： | 1 |
| 10 | Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma显示文摘 | Shunsuke Ura Masao Honda Taro Yamashita Teruyuki Ueda Hajime Takatori Ryuhei Nishino Hajime Sunakozaka Yoshio Sakai Katsuhisa Horimoto Shuichi Kaneko | 2009 | Hepatology2009，，4： | 1 |
| 11 | Evaluation of gut dysbiosis using serum and fecal bile acid profiles显示文摘Dysbiosis in the intestinal microflora can affect the gut production of microbial metabolites,and toxic substances can disrupt the barrier function of the intestinal wall,leading to the development of various diseases.Decreased levels of Clostridium subcluster XIVa(XIVa)are associated with the intestinal dysbiosis found in inflammatory bowel disease(IBD)and Clostridium difficile infection(CDI).Since XIVa is a bacterial group responsible for the conversion of primary bile acids(BAs)to secondary BAs,the proportion of intestinal XIVa can be predicted by determining the ratio of deoxycholic acid(DCA)/[DCA+cholic acid(CA)]in feces orserum.For example,serum DCA/(DCA+CA)was significantly lower in IBD patients than in healthy controls,even in the remission period.These results suggest that a low proportion of intestinal XIVa in IBD patients might be a precondition for IBD onset but not a consequence of intestinal inflammation.Another report showed that a reduced serum DCA/(DCA+CA)ratio could predict susceptibility to CDI.Thus,the BA profile,particularly the ratio of secondary to primary BAs,can serve as a surrogate marker of the intestinal dysbiosis caused by decreased XIVa. | Tadakuni Monma Junichi Iwamoto Hajime Ueda Makoto Tamamushi Fumio Kakizaki Naoki Konishi Shoichiro Yara Teruo Miyazaki Takeshi Hirayama Tadashi Ikegami Akira Honda | 2022 | World Journal of Clinical Cases2022，10，34： | 0 |
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