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1Homology-mediated end joining-based targeted integration using CRISPR/Cas9显示文摘Yao, Xuan Wang, Xing Hu, Xinde Liu, Zhen Liu, Junlai Zhou, Haibo Shen, Xiaowen Wei, Yu Huang, Zijian Ying, Wenqin Wang, Yan Nie, Yan-Hong Zhang, Chen-Chen Li, Sanlan Cheng, Leping Wang, Qifang Wu, Yan Huang, Pengyu Sun, Qiang Shi, Linyu Yang, Hui 2017Cell Research2017,27,6:28
2The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a chronic,progressive and debilitating disease,which affects over 2.5 million people in China.PD is characterized clinically by resting tremor,muscular rigidity,bradykinesia and postural instability.As the disease progresses,additional complications can arise such as non-motor and neurobehavioral symptoms.Pharmacological treatment and surgical intervention for PD have been implemented in China.Until 10 years ago,there was lack of standardization for the management of PD in different regions and among different physicians,leading to different treatment levels in different regions and different physicians.Since then,the Chinese Parkinson’s Disease and Movement Disorder Society have published three versions of guidelines for the management of PD in China,in 2006,2009 and 2014,respectively.Correspondingly,the overall level of treatment for PD in China improved.Objectives:To update the treatment guidelines based on current foreign and domestic practice guidelines and clinical evidence,and to improve the treatment options available to physicians in the management of PD.Summary:A variety of treatment recommendations in the treatment guidelines have been proposed,including physical activity and disease-modifying medication,which should be initiated at the early-stage of the disease.The principles of dosage titration should be followed to avoid acute adverse reactions to the drugs,to achieve a satisfactory clinical effect with a low dose and to reduce the incidence of long-term motor complications.Moreover,different treatment strategies should be considered at different stages of the disease.Importantly,treatment guidelines and personalized treatments should be valued equally.A set of treatment recommendations has been developed to assist physicians to improve and optimize clinical outcomes for patients with PD in China.Shengdi Chen Piu Chan Shenggang Sun Haibo Chen Baorong Zhang Weidong Le Chunfeng Liu Guoguang Peng Beisha Tang Lijuan Wang Yan Cheng Ming Shao Zhenguo Liu Zhenfu Wang Xiaochun Chen Mingwei Wang Xinhua Wan Huifang Shang Yiming Liu Pingyi Xu Jian Wang Tao Feng Xianwen Chen Xingyue Hu Anmu Xie Qin Xiao 2016Translational Neurodegeneration2016,5,1:23
3Internet of Vehicles in Big Data Era显示文摘As the rapid development of automotive telematics,modern vehicles are expected to be connected through heterogeneous radio access technologies and are able to exchange massive information with their surrounding environment. By significantly expanding the network scale and conducting both real-time and long-term information processing, the traditional Vehicular AdHoc Networks(VANETs) are evolving to the Internet of Vehicles(Io V), which promises efficient and intelligent prospect for the future transportation system. On the other hand, vehicles are not only consuming but also generating a huge amount and enormous types of data, which is referred to as Big Data. In this article, we first investigate the relationship between Io V and big data in vehicular environment, mainly on how Io V supports the transmission, storage, computing of the big data, and how Io V benefits from big data in terms of Io V characterization,performance evaluation and big data assisted communication protocol design. We then investigate the application of Io V big data in autonomous vehicles. Finally, the emerging issues of the big data enabled Io V are discussed.Wenchao Xu Haibo Zhou Nan Cheng Feng Lyu Weisen Shi Jiayin Chen Xuemin (Sherman) Shen 2018IEEE/CAA Journal of Automatica Sinica2018,5,1:19
4Cooperative Vehicular Content Distribution in Edge Computing Assisted 5G-VANET显示文摘By leveraging the 5G enabled vehicular ad hoc network(5G-VANET), it is widely recognized that connected vehicles have the potentials to improve road safety, transportation intelligence and provide in-vehicle entertainment experience. However, many enabling applications in 5G-VANET rely on the efficient content sharing among mobile vehicles, which is a very challenging issue due to the extremely large data volume, rapid topology change, and unbalanced traffic. In this paper, we investigate content prefetching and distribution in 5G-VANET. We first introduce an edge computing based hierarchical architecture for efficient distribution of large-volume vehicular data. We then propose a multi-place multi-factor prefetching scheme to meet the rapid topology change and unbalanced traffic. The content requests of vehicles can be served by neighbors, which can improve the sharing efficiency and alleviate the burden of networks. Furthermore, we use a graph theory based approach to solve the content distribution by transforming it into a maximum weighted independent set problem. Finally, the proposed scheme is evaluated with a greedy transmission strategy to demonstrate its efficiency.Guiyang Luo Quan Yuan Haibo Zhou Nan Cheng Zhihan Liu Fangchun Yang Xuemin (Sherman) Shen 2018China Communications2018,15,7:13
5Prostate cancer in Asia:A collaborative report显示文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers.Rui Chen Shancheng Ren Ming Kwong Yiu Ng Chi Fai Wai Sam Cheng Lap Hong Ian Seiji Naito Tadashi Matsuda Elijah Kehinde Ali Kural Jason Yichun Chiu Rainy Umbas Qiang Wei Xiaolei Shi Liqun Zhou Jian Huang Yiran Huang Liping Xie Lulin Ma Changjun Yin Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Xin Gao Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tiejun Pan Qiang Ding Fengshuo Jin Benkang Shi Gongxian Wang Xiuheng Liu Dongwen Wang Zhoujun Shen Xiangbo Kong Wanhai Xu Yaoliang Deng Haibo Xia Alexa NCohen Xu Gao Chuanliang Xu Yinghao Sun 2014Asian Journal of Urology2014,1,1:13
6Uncertainty analysis of hydrological model parameters based on the bootstrap method:A case study of the SWAT model applied to the Dongliao River Watershed,Jilin Province,Northeastern China显示文摘As an important tool for the description and analysis of hydrological processes,the watershed hydrological model has been increasingly applied to watershed hydrological simulations and water resource management.However,in most cases,model parameters are only determined in a calibration scheme which fits the modeled data to observations,thus significant uncertainties exist in the model parameters.How to quantitatively evaluate the uncertainties in model parameters and the resulting uncertainty impacts on model simulations has always been a question which has attracted much attention.In this study,two methods based on the bootstrap method(specifically,the model-based bootstrap and block bootstrap)are used to analyze the parameter uncertainties in the case of the SWAT(Soil and Water Assessment Tool)model applied to a hydrological simulation of the Dongliao River Watershed.Then,the uncertainty ranges of five sensitivity parameters are obtained.The calculated variation coefficients and the variable parameter contributions show that,among the five parameters,ESCO and CN2 have relatively high uncertainties:the variation coefficients and contribution rates are 23.98 and 70%,14.43 and 18%,respectively.The three remaining parameters have relatively low uncertainties.We compare the two uncertainty ranges of parameters acquired by the two bootstrap methods,and find that the uncertainty ranges of parameters acquired by the block bootstrap are narrower than those acquired by the model-based bootstrap.Further analysis of the effects of parameter uncertainties on the model simulation reveals that the parameter uncertainties have great impacts on results of the model simulation,and in the model calibration stage 60%70%of runoff observations were within the corresponding 95%confidence interval.The uncertainty in the model simulation during the flood season(i.e.the wet period)is relatively higher than that during the dry season.ZHANG Zheng LU WenXi CHU HaiBo CHENG WeiGuo ZHAO Ying 2014Science China(Technological Sciences)2014,57,1:9
7Effect of Carburization on the Mechanical Properties of Biomedical Grade Titanium Alloys显示文摘Yong Luo Haibo Jiang Gang Cheng Hongtao Liu 2011Journal of Bionic Engineering2011,8,1:7
86G service-oriented space-air-ground integrated network: A survey显示文摘As an indispensable component of the emerging 6G networks,Space-Air-Ground Inte-grated Networks(SAGINs)are envisioned to provide ubiquitous network connectivity and services by integrating satellite networks,aerial networks,and terrestrial networks.In 6G SAGINs,a wide variety of network services with the features of diverse requirements,complex mobility,and multi-dimensional resources will pose great challenges to service provisioning,which urges the develop-ment of service-oriented SAGINs.In this paper,we conduct a comprehensive review of 6G SAGINs from a new perspective of service-oriented network.First,we present the requirements of service-oriented networks,and then propose a service-oriented SAGINs management architec-ture.Two categories of critical technologies are presented and discussed,i.e.,heterogeneous resource orchestration technologies and the cloud-edge synergy technologies,which facilitate the interoperability of different network segments and cooperatively orchestrate heterogeneous resources across different domains,according to the service features and requirements.In addition,the potential future research directions are also presented and discussed.Nan CHENG Jingchao HE Zhisheng YIN Conghao ZHOU Huaqing WU Feng LYU Haibo ZHOU Xuemin SHEN 2022Chinese Journal of Aeronautics2022,35,9:6
9Harnessing the native type I-B CRISPR-Cas for genome editing in a polyploid archaeon显示文摘Research on CRISPR-Cas(clustered regularly interspaced short palindromic repeats-CRISPR associated protein) systems has led to the revolutionary CRISPR/Cas9 genome editing technique. However, for most archaea and half of bacteria, exploitation of their native CRISPR-Cas machineries may be more straightforward and convenient. In this study, we harnessed the native type I-B CRISPR-Cas system for precise genome editing in the polyploid haloarchaeon Haloarcula hispanica. After testing different designs, the editing tool was optimized to be a single plasmid that carries both the self-targeting miniCRISPR and a 600-800 bp donor. Significantly, chromosomal modifications, such as gene deletion, gene tagging or single nucleotide substitution, were precisely introduced into the vast majority of the transformants. Moreover, we showed that simultaneous editing of two genomic loci could also be readily achieved by one step. In summary, our data demonstrate that the haloarchaeal CRISPR-Cas system can be harnessed for genome editing in this polyploid archaeon, and highlight the convenience and efficiency of the native CRISPR-based genome editing strategy.Feiyue Cheng Luyao Gong Dahe Zhao Haibo Yang Jian Zhou Ming Li Hua Xiang 2017Journal of Genetics and Genomics2017,44,11:5
10Allosteric inhibition reveals SHP2-mediated tumor immunosuppression in colon cancer by single-cell transcriptomics显示文摘Colorectal cancer(CRC), a malignant tumor worldwide consists of microsatellite instability(MSI) and stable(MSS) phenotypes. Although SHP2 is a hopeful target for cancer therapy, its relationship with innate immunosuppression remains elusive. To address that, single-cell RNA sequencing wasperformed to explore the role of SHP2 in all cell types of tumor microenvironment(TME) from murine MC38 xenografts. Intratumoral cells were found to be functionally heterogeneous and responded significantly to SHP099, a SHP2 allosteric inhibitor. The malignant evolution of tumor cells was remarkably arrested by SHP099. Mechanistically, STING-TBK1-IRF3-mediated type I interferon signaling was highly activated by SHP099 in infiltrated myeloid cells. Notably, CRC patients with MSS phenotype exhibited greater macrophage infiltration and more potent SHP2 phosphorylation in CD68;macrophages than MSI-high phenotypes, suggesting the potential role of macrophagic SHP2 in TME. Collectively,our data reveals a mechanism of innate immunosuppression mediated by SHP2, suggesting that SHP2 is a promising target for colon cancer immunotherapy.Jian Gao Zhigui Wu Mingxia Zhao Rui Zhang Manru Li Dongdong Sun Haibo Cheng Xianjia Qi Yuxian Shen Qiang Xu Hongqi Chen Dijun Chen Yang Sun 2022Acta Pharmaceutica Sinica B2022,12,1:5
11Effects of different biochars on antibiotic resistance genes during swine manure thermophilic composting显示文摘Elimination of antibiotic resistance genes(ARGs)in animal manure from concentrated animal feeding operations by thermophilic composting has drawn increasing attention.This study investigated the effects of sawdust biochar,corn stover biochar and peanut hull biochar with three spiked levels on ARGs in swine manure during thermophilic composting.Thirteen ARGs corresponding to four classes of antibiotics(tetracyclines,sulfonamides,macrolides and quinolones)were determined in the composting piles.Results indicated that the ten tested composting groups became fully mature after 30-day thermophilic composting process.tetM,tetO and ermB were reduced in all tested groups;tetC and tetG,tetX,sul1,sul2,ermF,qnrD and aac(6’)-Ib were mostly reduced under low level biochar addition but increased under higher level biochar addition;gyrA increased under medium biochar addition and reduced in other groups;oqxB remained comparatively stable throughout the composting process.The addition levels of spiked biochar are more important than types of spiked biochar on the removal of ARGs in the composting pile.The average removal rates of ARGs in the control group,low,medium and high level biochar addition groups were 0.24 logs,0.52-0.72 logs,-0.52-0.18 logs and-0.19-0.21 logs,respectively.In summary,low level biochar addition could enhance the elimination of studied ARGs in swine manure during the composting process,while medium level biochar addition to the composting piles would increase the risk of ARGs’propagation.Jian Wang Bin Sui Yujun Shen Haibo Meng Lixin Zhao Haibin Zhou Ran Li Jingtao Ding Hongsheng Cheng Xi Zhang 2018International Journal of Agricultural and Biological Engineering2018,11,6:5
12Dietary nano-selenium alleviated intestinal damage of juvenile grass carp(Ctenopharyngodon idella)induced by high-fat diet:Insight from intestinal morphology,tight junction,inflammation,anti-oxidization and intestinal microbiota显示文摘In recent years,high-fat diet(HFD)has been widely applied in aquaculture,which reduces the intestinal health of cultured fish.The current study evaluated the protective effects of nano-selenium(nano-Se)on intestinal health of juvenile grass carp(Ctenopharyngodon idella)fed with HFD.A total of 135 experimental fish were fed with a regular diet(Con),a HFD(HFD)and a HFD containing nano-Se at 0.6 mg/kg(HSe)for 10 weeks.The results showed that dietary nano-Se significantly improved the survival rate and feed efficiency which were reduced by HFD in juvenile grass carp(P<0.05).Also,nano-Se(0.6 mg/kg)supplement alleviated intestinal damage caused by the HFD,thus maintaining the integrity of the intestine.Moreover,it significantly up-regulated the expression of genes related to tight junction(ZO-1,claudin-3 and occludin),anti-oxidization(GPx4a and GPx4b),and the protein of ZO-1 in the intestine of juvenile grass carp,which were depressed by the HFD(P<0.05).Furthermore,nano-Se supplementation significantly suppressed the expressions of genes related to the inflammation,including inflammatory cytokines(IL-8,IL-1β,IFN-γ,TNF-αand IL-6),signaling molecules(TLR4,p38 MAPK and NF-kB p65),and protein expression of NF-kB p65 and TNF-αin the intestine of juvenile grass carp which were induced by the HFD(P<0.05).Besides,dietary nano-Se normalized the intestinal microbiota imbalance of juvenile grass carp caused by the HFD through increasing the abundance of the beneficial bacteria,e.g.,Fusobacteria.Finally,dietary nano-Se increased the production of short chain fatty acids(SCFA)in the intestine,especially for butyric acid and caproic acid,which were negatively related to the increase of intestinal permeability and inflammation.In summary,supply of nano-Se(0.6 mg/kg)in HFD could effectively alleviate intestinal injury of juvenile grass carp by improving intestinal barrier function and reducing intestinal inflammation and oxidative stress.These positive effects may be due to the regulation of nano-Se on intestinal microbiota and the subsequently increased beneficial SCFA levels.Sha Liu Haibo Yu Pengju Li Chi Wang Guohao Liu Xiaotian Zhang Cheng Zhang Meng Qi Hong Ji 2022Animal Nutrition2022,,1:4
13Metagenome analysis reveals potential microbial functions in topsoil of wheat-maize rotation system with five-year application of fertilizers显示文摘Fertilization mode affects soil quality and ecological health.The effects of four fertilization regimens on lignocellulose content,readily degradable carbohydrate decomposition,and potential microbial functions in the topsoil of a wheat-maize rotation system between 2012 and 2017 were investigated.The fertilization regimens of control(control NFNB),high chemical fertilizer(HCF),high biochar plus low chemical fertilizer(HBLCF),and biochar-based fertilizer(BBF)were compared on soil fundamental properties,microbial structure,and potential function in soil carbohydrate degradation based on metagenome analysis.The diversity of carbohydrate-active enzyme genes in the topsoil microbial consortia in the four trials was primarily distributed within the ten ecologically most dominant phyla.Application of BBF was associated with the lowest decline in total nitrogen and P2O5(2012-2017:6.5%and 28.1%,respectively)and the most effective carbohydrate decomposition(2015-2017:67.0%for cellulose and 59.9%for readily degradable carbohydrate).Carbohydrate transport and metabolism accounted for 6.0%of reads assigned functional classification under the BBF regimen.These findings reveal the ecologically functional diversity of topsoil microorganisms and suggest BBF application as a promising strategy for sustainable agriculture and beneficial to soil health.Yujun Shen Lixin Zhao Haibo Meng Hongsheng Cheng Jingtao Ding Jiarui Wang Shanshan Dong Xi Zhang Liqiu Song Shengwei Zheng 2019International Journal of Agricultural and Biological Engineering2019,12,6:3
14The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs.Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou 2023Horticulture Research2023,10,5:3
15PtNi-W/C with Atomically Dispersed Tungsten Sites Toward Boosted ORR in Proton Exchange Membrane Fuel Cell Devices显示文摘The performance of proton exchange membrane fuel cells is heavily dependent on the microstructure of electrode catalyst especially at low catalyst loadings.This work shows a hybrid electrocatalyst consisting of PtNi-W alloy nanocrystals loaded on carbon surface with atomically dispersed W sites by a two-step straightforward method.Single-atomic W can be found on the carbon surface,which can form protonic acid sites and establish an extended proton transport network at the catalyst surface.When implemented in membrane electrode assembly as cathode at ultra-low loading of 0.05 mgPt cm^(−2),the peak power density of the cell is enhanced by 64.4%compared to that with the commercial Pt/C catalyst.The theoretical calculation suggests that the single-atomic W possesses a favorable energetics toward the formation of*OOH whereby the intermediates can be efficiently converted and further reduced to water,revealing a interfacial cascade catalysis facilitated by the single-atomic W.This work highlights a novel functional hybrid electrocatalyst design from the atomic level that enables to solve the bottle-neck issues at device level.Huawei Wang Jialong Gao Changli Chen Wei Zhao Zihou Zhang Dong Li Ying Chen Chenyue Wang Cheng Zhu Xiaoxing Ke Jiajing Pei Juncai Dong Qi Chen Haibo Jin Maorong Chai Yujing Li 2023Nano-Micro Letters2023,15,9:3
16Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling显示文摘Dear Editor,Colorectal cancer(CRC)is one of the most frequent diseases with high mortality around the world.Conventional treatments of CRC remain unsatisfactory due to the increasing recurrence rate and adverse reactions including neutropenia,drug resistance,etc.Recently,autophagy has been shown to be involved in regulating cancer development and progression by regulating apoptosis through pro-apoptosis proteins including caspases,in addition to being a potential target for cancer therapeutic intervention.1 Trifolirhizin(Supplementary Fig.S1a)is a natural flavonoid glycosides isolated from Sophora flavescens as well as a bioactive constituent of Xian-Lian-Ke-Li,a commercial traditional Chinese medicine for the cancer prevention.Numerous evidence manifested that trifolirhizin inhibited proliferative activity in melanoma B16 cell,lung cancer H23 cell,human ovarian A2780 cell,and human gastric cancer cell MKN45.2 However,its pharmacological effect and mechanism on CRC remain elusive.Herein,we evaluated the effect of trifolirhizin on autophagy and apoptosis on CRC as well as its related mechanisms,in order to provide evidence to develop a potential agent with less adverse effect in treating CRC.Dongdong Sun Weiwei Tao Feng Zhang Weixing Shen Jiani Tan Liu Li Qinghai Meng Yugen Chen Ye Yang Haibo Cheng 2020Signal Transduction and Targeted Therapy2020,5,1:3
17Investigation and analysis of the linkage mechanism and whole process cost of livestock manure organic fertilizer显示文摘In recent years,the utilization of manure resources for livestock and poultry farming has attracted a widespread attention,and manure resources utilization models suitable for different regional characteristics have formed gradually.Among them,the production of organic fertilizer from animal manure is a vital utilization method.However,there are still some problems such as high production costs,difficult sales,and the unwillingness of farmers to use organic fertilizers which have affected the breeding cycle and the sustainability of manure treatment in livestock and poultry breeding.This article selected 371 organic fertilizer plants,related farms and farmers in China,focusing on the main links of the entire process of livestock manure-organic fertilizer-farm application,and studied the mode of animal manure collection by organic fertilizer plants.The costs of organic fertilizer production and farmland application were discussed.Moreover,suggestions were made for the promotion and implementation of large-scale organic fertilizers to make good utilization of manure resources in livestock and poultry farming.Shanshan Dong Bin Sui Yujun Shen Haibo Meng Lixin Zhao Jingtao Ding Haibin Zhou Xi Zhang Hongsheng Cheng Jian Wang Ran Li Liqiu Song Pengxiang Xu Ji Li 2020International Journal of Agricultural and Biological Engineering2020,13,2:2
18A pH Model for Calculating the pH Value of Mixed–Acid–Base Equilibria of Overhead Condensing Systems in Crude Distillation显示文摘A pH predictive model based on acid–base equilibria and ion equilibria was proposed to calculate the pH value of the overhead condensing system of crude distillation unit. The pH model could be used to predict the appropriate amounts of neutralizers by measuring the Cl-ion concentration of the overhead knockout drum. The pH values of various neutralized streams were estimated by this model. The results showed that the predicted pH values were in good agreement with the experimental ones. The trend of the corrosion inhibition efficiency decreases in the following order: ethylenediamine > N,Ndimethylethanolamine> triethylamine > 3-methoxypropylamine > morpholine. The difficulty in the accurate control of corrosion was solved, and a good instruction was provided for mitigating corrosion in refinery.Wang Haibo Li Yun Cheng Guangxu Wu Wei Chen Xuan Zhang Yaoheng Li Xinyun 2017China Petroleum Processing & Petrochemical Technology2017,19,4:2
19Graphene Oxide Assemblies for Sustainable Clean-Water Harvesting and Green-Electricity Generation显示文摘CONSPECTUS:The urgent problems of water scarcity and the energy crisis have given rise to the development of a range of sustainable technologies with the great advancement of nanotechnologies and advent of attractive nanomaterials.Graphene oxides(GO),a derivative of graphene with an atom-thin thickness and abundant oxygen-containing functional groups(such as−OH,−COOH),are water-soluble and can be assembled into a variety of structures(such as fiber,membrane,and foam)with great potential in environmental and energy-related fields.As a typical precursor of graphene,GO can be easily reduced to graphene by chemical or thermal treatments to demonstrate excellent photothermal properties as well as tunable thermal conduction,which is highly desirable for efficient solar-driven water evaporation.The intrinsic large specific area of GO nanosheets can provide enough sites for ions adsorption and its porous assemblies facilitate the transport of water.In addition,the abundant functional groups allow the spontaneous adsorption of water molecules from the ambient environment and give birth to movable ions(usually protons)under the solvation effect.Once a chemical gradient is formed on the component,a remarkable electricity is generated from the directional transport of protons.Thanks to the excellent chemical properties of GO nanosheets,a wide range of assemblies with 1D aligned fibers,2D layered membranes and 3D porous foam can be easily fabricated by wet-spinning,solution-filtration,and freezingdrying methods.The various GO assemblies are able to exhibit abundant functions with remarkable weaving capability for GO fibers,superior flexibility for GO membranes,and exceptional adsorption capacity for GO foams.In light of all the advantages,GO and its assemblies are remarkably promising in the fields of sustainable development to meet the pressing challenges of water and energy crisis.In this Account,we will discuss the progress of clean-water production and green-electricity generation technologies based on GO assemblies.The fundamental working mechanism,optimization strategies,and promising applications are explored with an emphasis on the materials development.We also discuss the functions of GO assemblies in the water and electricity generation process and present their limitations and possible solutions.Current challenges and promising directions for the development of clean-water production and green-electricity generation are also demonstrated for their realistic implementations.We anticipate that this Account would promote more efforts toward fundamental research on graphene functionalization and encourage a broad exploration on the application of graphene assemblies in clean-water production and electric power generation systems.Yaxin Huang Chengzhi Wang Changxiang Shao Boyu Wang Nan Chen Haibo Jin Huhu Cheng Liangti Qu 2021Accounts of Materials Research2021,2,2:2
20Effect of Metaxenia on Sugars and Organic Acids and Taste Quality of Bagged Fuji Apple Fruits显示文摘In order to provide reference for the selection of appropriate pollination varieties facilitating the improvement of the flavor quality of bagged Fuji apple,the metaxenia effects of 5 pollination varieties on sugars,organic acids and flavor quality of bagged Fuji fruit were studied.The results showed that the 5 pollination varieties had significant metaxenia effects on sugars,organic acids and flavor quality of bagged Fuji fruit.For the sugar components,the fruits pollinated with Golden Delicious and Jinxiuhaitang showed higher glucose contents,and the fruit pollinated with Gala had the highest sucrose content;the fruits pollinated by Gala,Golden Delicious and Ruby exhibited higher malic acids,and the oxalic acid content and the succinic acid content were higher in the fruits pollinated with Jinxiuhaitang and Ruby;and the fruit pollinated with Gala had the highest total sugar content,and the total acid content was higher in the fruits pollinated by Jinxiuhaitang and Ruby.The sugar-acid ratio was higher in the fruits pollinated with Gala and Golden Delicious,and the lowest in the fruit pollinated with Ruby.The sensory evaluation of fruits showed that the fruit pollinated with Ruby tasted sour-sweet,while the fruits pollinated with other 4 pollination varieties were sour and sweet moderately.Haibo WANG Chuanzeng WANG Lailiang CHENG Yuansheng CHANG Ping HE Linguang LI 2017Agricultural Biotechnology2017,6,4:2
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