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| 1 | Predictors of response to antiviral therapy in patients with chronic hepatitis C from Pakistani population显示文摘背景丙肝病毒(HCV ) 在全世界组成一个主要公共健康问题,特别在开发象巴基斯坦一样的国家。在这研究,我们估计了在长期的丙肝病人的治疗在这研究由性,年龄,和病毒的 load.Methods 分类的干扰素(INF ) 的结果,有遗传型 3 的 750 个 HCV 积极病人被选择,从哪个 616 完成了全部治疗。他们的个人历史,支持处理的 HCV RNA 和浆液丙氨酸 transaminase (中高音) 是 quantified.Patients 与 INF- 2b 的联合治疗被对待 300 万个单位(三次一个星期) 正 ribavirin (1000-1200mg 每天) 为 24 个星期。在 24 个星期以后,他们的 HCV RNA 和浆液中高音水平是从 616 个病人,的 quantified.Results (63.5%) 391 对治疗学的政体(加 ribavirin 的 INF- 2b ) 作出回应。在应答者之中, 27.1% 是男人, 36.4% 是女人。最好的治疗反应在有 Iow 的病人被观察病毒的负担 8 ?????牴湡睳汥 吗?? | Hafsa Aziz Muhammad Amin Athar Shahnaz Murtaza Javaid Irfan Yasir Waheed Iram Bilal Abida Raza | 2011 | Chinese Medical Journal2011，，9： | 6 |
| 2 | Biosynthesis of Flower-Shaped CuO Nanostructures and Their Photocatalytic and Antibacterial Activities显示文摘Copper oxide nanoflowers(CuO-NFs)have been synthesized through a novel green route using Tulsi leaves-extracted eugenol(4-allyl-2-methoxyphenol)as reducing agent.Characterizations results reveal the growth of crystalline singlephase CuO-NFs with monoclinic structure.The prepared CuO-NFs can effectively degrade methylene blue with 90%efficiency.They also show strong barrier against E.coli(27±2 mm)at the concentration of 100μg mL−1,while at the concentration of 25μg mL−1 weak barrier has been found against all examined bacterial organisms.The results provide important evidence that CuO-NFs have sustainable performance in methylene blue degradation as well as bacterial organisms. | Hafsa Siddiqui MSQureshi Fozia Zia Haque | 2020 | Nano-Micro Letters2020，12，2： | 4 |
| 3 | Preparation and Control of the Formation of Single Core and Clustered Nanoparticles for Biomedical Applications Using a Versatile Amphiphilic Diblock Copolymer显示文摘We report the application of a versatile diblock copolymer,poly(ethylene oxide)-b-poly(γ-methacryloxypropyl trimethoxysilane)(PEO-b-PγMPS),to prepare nanocrystals such as iron oxide nanoparticles or quantum dots,with either a single core or multi-core cluster,for biomedical applications.This amphiphilic copolymer comprises both a hydrophilic PEO segment and a hydrophobic segment with a“surface anchoring moiety”(the silane group)which can interact effectively with the hydrophobic nanocrystals through ligand exchange.One of the unique features of this work is that we can control the formation of either single core nanoparticles or multi-core nanoclusters by simply varying the conditions of ligand exchange and aging of the mixture of block copolymer and nanoparticles without needing to change the copolymer.The morphologies of the resulting single core nanoparticles or multi-core nanoclusters were confirmed by dynamic light scattering and transmission electron microscopy.The clustered nanoparticles exhibit enhanced physicochemical properties that are beyond those expected from a simple accumulation of individual nanoparticles.Additionally,the hybrid nanoparticles containing both magnetic iron oxide nanoparticles and optical quantum dots obtained using our strategy provide have combined magnetic and optical functionalities that allow for potential new and expanded biomedical applications,as demonstrated by their use for magnetic resonance imaging and biomarker-targeted cell imaging. | Hongwei Chen Julie Yeh Liya Wang Hafsa Khurshid Nan Peng Andrew YWang Hui Mao | 2010 | Nano Research2010，3，12： | 3 |
| 4 | Update on clinical and research application of fecal biomarkers for gastrointestinal diseases显示文摘Gastrointestinal(GI) diseases comprise a large spectrum of clinical conditions ranging from indigestion to inflammatory bowel diseases(IBDs) and carcinomas. Endoscopy is the usual method employed to diagnose these condition. Another noninvasive way to assess and diagnose GI conditions are fecal biomarkers. Fecal biomarkers provide information regarding a specific disease process and are perhaps more acceptable to clinicians and patients alike because of their non-invasivity compared to endoscopy. Aim of this review was to evaluate the current status of the fecal biomarkers in clinical and research for in GI diseases. Multiple types of fecal biomarkers are discussed in this review including; markers to assess IBD, which are released as a results of an inflammatory insults to intestinal epithelia such as antimicrobial peptides(lactoferrin) or inflammation related proteins(calprotectin). While markers related to function of digestion are primarily related to partially digested food or mucosal proteins such as abnormal amount of fecal fat α1-antitrypsin, elastase and secretary IgA. The upcoming fecal biomarker like M2 pyruvate kinase and neutrophil gelatinase associated lipocalin are discussed as well. Apart from above mention, the fecal biomarkers under exploration for possible clinical use in future are also discussed. These include cathelicidins, osteoprotegerin, β-glucuronidase, Eosinophil proteins, etc. | Imran Siddiqui Hafsa Majid Shahab Abid | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，1： | 2 |
| 5 | 全视网膜光凝术改善PDR患者的视觉相关生活质量及日常视觉功能(英文)显示文摘目的:评估全视网膜光凝术(PRP)对糖尿病视网膜病变(PDR)患者在视觉相关生活质量及日常视觉功能的影响。方法:研究纳入30例(男13例,女17例)接受全视网膜光凝术治疗糖尿病视网膜病变患者。国家眼科研究所发布的视觉功能量表(VFQ-25)用来评估全视网膜光凝术治疗前后视觉相关生活质量及日常视觉功能。患者在接受全视网膜光凝术治疗前和治疗后6mo分别填写VFQ-25量表,比较视觉相关生活质量及日常视觉功能差异。运用配对t检验对治疗前后VFQ-25评分对比。结果:全视网膜光凝术治疗前平均VFQ-25综合评分为74.79±15.7,术后平均综合评分为74.08±19.1。术前与术后的平均VFQ-25综合评分无统计学意义(P=0.875)。结论:全视网膜光凝术(PRP)对糖尿病视网膜病变(PDR)患者在视觉相关生活质量及日常视觉功能无不利影响。 | Muhammad Imran Saleem Channar Muhammad Farhan Saleem Hafsa Malik | 2016 | 国际眼科杂志2016，16，12： | 2 |
| 6 | Laparoscopic manage- ment of adnexa] tumors after the first trimester of pregnancy显示文摘 | Boughizane S Nailer R Hafsa A | 2004 | J Gynecol Obstet Biol Reprod (Paris)2004，33，4： | 1 |
| 7 | HPLC sugar profiles of Algerian honeys显示文摘 | Salim Ouchemoukh Paul Schweitzer Mostapha Bachir Bey Hafsa Djoudad-Kadji Hayette Louaileche | 2009 | Food Chemistry2009，，2： | 1 |
| 8 | Rapid virological response tailors the duration of treatment in hepatitis C virus genotype 3 patients treated with pegylated interferon alfa-2a and ribavirin in Pakistan显示文摘 | Uzma Gill Hafsa Aziz Muzaffar Lateef Gill | 2013 | International Journal of Infectious Diseases2013，，： | 1 |
| 9 | Study of Fractional Order Dynamical System of Viral Infection Disease under Piecewise Derivative显示文摘This research aims to understand the fractional order dynamics of the deadly Nipah virus(NiV)disease.We focus on using piecewise derivatives in the context of classical and singular kernels of power operators in the Caputo sense to investigate the crossover behavior of the considered dynamical system.We establish some qualitative results about the existence and uniqueness of the solution to the proposed problem.By utilizing the Newtonian polynomials interpolation technique,we recall a powerful algorithm to interpret the numerical findings for the aforesaid model.Here,we remark that the said viral infection is caused by an RNA type virus which can transmit from animals and also from an infected person to person.Fruits bats which are also known as flying foxes are one of the sources of transmission of NiV disease.Here in this work,we investigate its transmission mechanism through some new concepts of fractional calculus for further analysis and prediction.We present the approximate results for different compartments using different fractional orders.By using the piecewise derivative concept,we detect the crossover ormulti-steps behavior in the transmission dynamics of the mentioned disease.Therefore,the considered form of the derivative is used to deal with problems exhibiting crossover behaviors. | Kamal Shah Hafsa Naz Thabet Abdeljawad Bahaaeldin Abdalla | 2023 | Computer Modeling in Engineering & Sciences2023，，7： | 1 |
| 10 | Arachnoiditis ossificans of the lumbar spine:a case report显示文摘 | Kriaa S Hafsa C Zbidi M | 2006 | Joint Bone Spine2006，73，6： | 1 |
| 11 | 黏性颗粒在聚偏氟乙烯纤维膜内部沉积特性数值模拟显示文摘为了探究黏性颗粒在纤维过滤介质上的沉积特性,通过随机算法建立聚偏氟乙烯纤维膜的三维模型,并采用离散单元法进行了纤维膜内部的气固流动模拟,引入JKR颗粒接触模型,研究了颗粒表面能与碰撞恢复系数对黏性颗粒的运动与沉积特性影响,获得了黏性颗粒在纤维表面沉积的最佳表面能和碰撞恢复系数,并在此基础上研究了粒径2~7μm黏性颗粒的沉积与受力情况。结果表明:颗粒表面能、恢复系数与粒径均为影响黏性颗粒沉积特性的重要因素,表面能的减小,恢复系数或粒径的增大,能够使捕集效率增大,颗粒在纤维表面更易形成稳定的沉积与团聚形态。 | 诸文旎 刘倩倩 JAMSHAID Hafsa 李莉 祝国成 | 2022 | 现代纺织技术2022，30，5： | 1 |
| 12 | Analysis of variables and interactions among variables associated with a sustained virological response to pegylated interferon alfa-2a plus ribavirin in hepatitis C virus genotype 3-infected patients显示文摘 | Hafsa Aziz Abida Raza Yasir Waheed Uzma Gill Muzaffar Lateef Gill | 2012 | International Journal of Infectious Diseases2012，，8： | 1 |
| 13 | Evaluation of prognostic factors for Peg Interferon alfa-2b plus ribavirin treatment on HCV infected patients in Pakistan显示文摘 | Hafsa Aziz Muzaffar Latif Gil Yasir Waheed Uzama Adeeb Abida Raza Iram Bilal Muhammad Amin Athar | 2011 | Infection Genetics and Evolution2011，，3： | 1 |
| 14 | Evaluation of FDM pattern with ABS and PLA material显示文摘 | Hafsa M N Wahab M S Zahid M S | 2013 | Applied Mechanics and Materials2013，46，： | 1 |
| 15 | Spinal cord compression revealing fluorosis 显示文摘 | Hafsa C Zaghouani H Kriaa S | 2008 | Joint Bone Spine2008，75，1： | 1 |
| 16 | Evaluation of Iodine-Glycerol for Wet-Mount Preparation of Feces for Detection of Intestinal Parasites显示文摘 | Hafsa Afroza Raisul Alamad GM Manjur Hossain MD | 2013 | Int J Biol Med Res2013，4，4： | 1 |
| 17 | Use of the Capripoxvirus homologue of Vaccinia virus 30<ce:hsp sp='0.25'/>kDa RNA polymerase subunit (RPO30) gene as a novel diagnostic and genotyping target: Development of a classical PCR method to differentiate Goat poxvirus from Sheep poxvirus显示文摘 | Charles Euloge Lamien Christian Le Goff Roland Silber David B. Wallace Vely Gulyaz Eeva Tuppurainen Hafsa Madani Philippe Caufour Tajelser Adam Mehdi El Harrak Antony George Luckins Emmanuel Albina Adama Diallo | 2010 | Veterinary Microbiology2010，，1： | 1 |
| 18 | Effects of Carpobrotus edulis Extract on Oxidative Stress and 158N Oligodendrocyte Death显示文摘Objective Age-related diseases, including neurodegenerative diseases, are associated with oxidative stress and lipid peroxidation, and increase the levels of cholesterol auto-oxidation products such as 7β-hydroxycholesterol(7β-OHC). Thus, it is imperative to identify agents that can prevent 7β-OHC-induced side-effects. Methods We evaluated the potential protective effects of Carpobrotus edulis ethanol-water extract(EWe) on murine oligodendrocytes(158 N) cultured in the absence or presence of 7β-OHC(20 μg/mL, 24 h). The cells were incubated with EWe(20-200 μg/mL) 2 h before 7β-OHC treatment. Mitochondrial activity and cell growth were evaluated with the MTT assay. Photometric methods were used to analyze antioxidant enzyme [catalase(CAT) and glutathione peroxidase(GPx)] activities and the generation of lipid and protein oxidation products [malondialdehyde(MDA), conjugated diene(CD), and carbonylated proteins(CPs)]. Results Treatment with 7β-OHC induced cell death and oxidative stress(reflected by alteration in CAT and SOD activities). Overproduction of lipid peroxidation products(MDA and CDs) and CPs was also reported. The cytotoxic effects associated with 7β-OHC were attenuated by 160 μg/mL of EWe of C. edulis. Cell death induced by 7β-OHC treatment was ameliorated, GPx and CAT activities were restored to normal, and MDA, CD, and CP levels were reduced following C. edulis extract treatment. Conclusion These data demonstrate the protective activities of C. edulis EWe against 7β-OHC-induced disequilibrium in the redox status of 158 N cells, indicative of the potential role of this plant extract in the prevention of neurodegenerative diseases. | Amira Zarrouk Mohammed Ali Smach Jawhar Hafsa Randa Sghaier Hatem majdoub Mohammed Hammami Bassem Charfeddine | 2019 | Biomedical and Environmental Sciences2019，32，4： | 1 |
| 19 | Fruits and Vegetables Freshness Categorization Using Deep Learning显示文摘The nutritional value of perishable food items,such as fruits and vegetables,depends on their freshness levels.The existing approaches solve a binary class problem by classifying a known fruit\vegetable class into fresh or rotten only.We propose an automated fruits and vegetables categorization approach that first recognizes the class of object in an image and then categorizes that fruit or vegetable into one of the three categories:purefresh,medium-fresh,and rotten.We gathered a dataset comprising of 60K images of 11 fruits and vegetables,each is further divided into three categories of freshness,using hand-held cameras.The recognition and categorization of fruits and vegetables are performed through two deep learning models:Visual Geometry Group(VGG-16)and You Only Look Once(YOLO),and their results are compared.VGG-16 classifies fruits and vegetables and categorizes their freshness,while YOLO also localizes them within the image.Furthermore,we have developed an android based application that takes the image of the fruit or vegetable as input and returns its class label and its freshness degree.A comprehensive experimental evaluation of proposed approach demonstrates that the proposed approach can achieve a high accuracy and F1score on gathered FruitVeg Freshness dataset.The dataset is publicly available for further evaluation by the research community. | Labiba Gillani Fahad Syed Fahad Tahir Usama Rasheed Hafsa Saqib Mehdi Hassan Hani Alquhayz | 2022 | Computers, Materials & Continua2022，，6： | 1 |
| 20 | Chronic hepatitis-C infection in COVID-19 patients is associated with in-hospital mortality显示文摘BACKGROUND There is little evidence about the association of pre-existing hepatitis C infection(HCV)with outcomes in patients with coronavirus disease 2019(COVID-19).AIM To assess the prevalence of history of HCV among patients with COVID-19 and to study the relationship of in-hospital mortality in relation with other predictors of poor outcomes in the presence or absence of COVID-19 induced acute liver injury.METHODS In a retrospective single-center study design,1193 patients with COVID-19 infection were studied.Patients were then classified into those with and without a history of HCV,50(4.1%)and 1157(95.9%)respectively.RESULTS Multivariate cox-regression models showed that age,HCV,D-Dimer,and ferritin were the only predictors of in-hospital mortality.Acute liver injury and fibrosis score(Fib-4 score)were not different between both groups.Multivariate coxregression model for liver profile revealed that aspartate aminotransferase/alanine aminotransferase ratio,Fib-4 score,and HCV were predictors of inhospital mortality.After propensity score matching HCV was the only predictor of mortality in the multivariate cox-regression model.A model including HCV was found to add predictive value to clinical and laboratory parameters.CONCLUSION In patients with COVID-19,history of HCV infection leads to an accentuated severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)virulence,irrespective of baseline comorbidities,admission laboratory variables,or COVID-19-induced liver injury,which may be related to extrahepatic effects of HCV leading to enhanced ACE-2/TMPRSS mechanisms of SARS-CoV-2 viral entry,baseline cytokine-mediated pro-inflammation,and endothelial dysfunction. | Diana Ronderos Alaa Mabrouk Salem Omar Hafsa Abbas Jasbir Makker Ahmed Baiomi Haozhe Sun Nikhitha Mantri Yongsun Choi Ked Fortuzi Dongmin Shin Harish Patel Sridhar Chilimuri | 2021 | World Journal of Clinical Cases2021，9，29： | 1 |
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