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| 1 | Ganoderma Lucidum polysaccharide peptides protect kidney from renal ischemia reperfusion injury via counteracting oxidative stress显示文摘OBJECTIVE Ganoderma lucidum polysaccharide peptides(GLPP)have an anti-oxidant activity.The oxidative stress implicates in the pathogenesis of renal ischemia-reperfusion injury(RIRI).The objective of this study was to determine whether GLPP could attenuate RIRI via counteracting the oxidative stress.METHODS Mice subjected to uninephrectomy with the right kidney ischemia for 35 min and reperfusion for 24 hwere used to explore the protective activity of GLPP against RIRI.In GLPP-treated group,100mg·kg-1·d-1 of GLPP were intraperitoneally injected for 7dbefore the procedure.In vitro,NRK-52 Ecells subjected to hypoxia-reoxygenation(H/R)and tunicamycin were used to explore the protective effect of GLPP against oxidative stress.The mechanisms in which GLPP protected kidney from RIRI were studied using a series of physiological and molecular biological methods.RESULTS Kidneys undergone ischemia-reperfusion showed renal dysfunction and characteristic morphological changes including cellular necrosis,brush border loss,cast formation,vacuolization and tubular dilatation while these damages were significantly attenuated by GLPP treatment.The abnormal levels of MPO,MDA and SOD caused by renal ischemia-reperfusion were significantly reversed by GLPP treatment.More apoptotic cells were found in the renal ischemia-reperfusion group than the sham group whereas GLPP reduced apoptotic cells in the ischemia-reperfusion mice by21.75%(P<0.01).The GLPPs(25-1μg·mL)alleviated H/R induced cell viability loss by 20.12%(P<0.01)andΔφm dissipation by 27.3%(P<0.01)in vitro as well and its pretreatment dramatically reduced H/R and tunicamycin induced cell injury.CONCLUSION Our study found that GLPP had a protective effect on RIRI via its anti-oxidative capacity,which suggests that GLPP may be developed as a candidate drug for preventing acute kidney injury. | Dan-danZHONG Hong-kaiWANG MingLIU Ying-liJIA MingHUANG HongZHOU Shu-qianLIN Zhi-binLIN Bao-xueYANG | 2015 | 中国药理学与毒理学杂志2015，29，S1： | 21 |
| 2 | SPACECRAFT DOCKING SIMULATION USING HARDWARE-IN-THE-LOOP SIMULATOR WITH STEWART PLATFORM显示文摘A ground-based hardware-in-the-loop (HIL) simulation system with hydraulically drivenStewart platform for spacecraft docking simulation is presented. The system is used for simulatingdocking process of the on-orbit spacecraft. Principle and structure of the six-degree-of-freedom simu-lation system are introduced. The docking process dynamic of the vehicles is modeled. Experimentresults and mathematical simulation data are compared to validating the simulation system. The com-parisons of the results prove that the simulation system proposed can effectively simulate the on-orbitdocking process of the spacecraft. | Huang Qitao Jiang Hongzhou Zhang Shangying Han Junwei | 2005 | Chinese Journal of Mechanical Engineering2005，18，3： | 12 |
| 3 | Research progress of aluminum alloy automotive sheet and application technology显示文摘Pretreatment technology is deeply discussed to explain its importance in guaranteeing properties and formability of aluminum alloy automotive sheet. Some typical applications of aluminum alloy automotive sheet to automotive industry are listed. Based on the author's knowledge and recognition and research progress presently, the important research contents about aluminum alloy automotive sheet are emphasized. Reducing cost and price of sheet and going deeply into application research are the main work for expending the application of aluminum alloy automotive sheet in the automobile. | Ma Mingtu You Jianghai Lu Hongzhou Wang Zhiwen | 2012 | Engineering Sciences2012，10，4： | 10 |
| 4 | On the automobile lightweight显示文摘The significance,description parameters,evaluation method,implement way and design for lightweight of automobile are comprehensively reviewed.The relationship among the performances of auto parts & components,the properties of materials and application of advanced technologies is also elaborated.According to recently related progress of lightweight and authors' research and developing work,lightweight of automobile is comprehensively and systematically overviewed. | Ma Mingtu Yi Hongliang Lu Hongzhou Wan Xinming | 2012 | Engineering Sciences2012，10，2： | 8 |
| 5 | Influence of Magnetic Reluctances of Magnetic Elements on Servo Valve Torque Motors显示文摘The current research of electro-hydraulic servo valves mainly focuses on the vibration, pressure oscillating and source of noise. Unfortunately, literatures relating to the study of the influence of the magnetic reluctances of the magnetic elements are rarely available. This paper aims to analyze the influence of the magnetic reluctances of the magnetic elements on torque motor. Considering these magnetic reluctances ignored in previous literatures, a new mathematical model of servo valve torque motor is developed and proposed based on the fundamental laws of electromagnetism. By using this new mathematical model and the previous models, electromagnetic torque constant and magnetic spring stiffness are evaluated for a given set of torque motor parameters. A computer simulation by using AMESim software is also performed for the same set of torque motor parameters to verify the proposed model. The theoretical results of electromagnetic torque constant and magnetic spring stiffness evaluated by the proposed model render closer agreement with the simulation results than those evaluated by the previous models. In addition, an experimental measurement of the magnetic flux densities in the air-gaps is carried out by using SFL218 servo valve torque motor. Compared with the theoretical results of the magnetic flux densities in the air-gaps evaluated by the previous models, the theoretical results evaluated by the proposed model also show better agreement with the experimental data. The proposed model shows the influence of the magnetic reluctances of the magnetic elements on the servo valve torque motor, and offers modified and analytical expressions to electromagnetic torque constant and magnetic spring stiffness. These modified and analytical expressions could provide guidance more accurately for a linear control design approach and sensitivity analysis on electro-hydraulic servo valves than the previous expressions. | LIU Changhai JIANG Hongzhou | 2016 | Chinese Journal of Mechanical Engineering2016，29，1： | 8 |
| 6 | Occurrence of Haloacetic Acids in Drinking Water in Certain Cities of China显示文摘Objective Since haloacetic acids (HAAs), which are nonvolatile and of high carcinogenic risk, are common species of chlorinated disinfection by-products(DBPs) in drinking water, and little has been known in China, it is necessary to make a survey about the kinds and levels of HAAs in drinking water of the nation. Method HAAs were analyzed using gas chromatography with electron capture detector(GC/ECD) and relatively complex pretreatment process of sample was applied. Five main cities in different areas of China were chosen in the survey. Results Studies showed that the main species of HAAs in drinking water in China were DCAA and TCAA, ranging from 0.4 礸/L to 12.85 礸/L and from 0.56 礸/L to 10.98 礸/L, respectively. MBAA and DBAA were also detected in one city, ranging from 2.20 礸/L to 4.95 礸/L and 1.10 礸/L to 2.81 礸/L, respectively. Therefore, the contents of HAAs varied, usually no more than 25 礸/L. Based on the acquired data to date, it is known that the concentrations of HAAs in drinking water in China were surely under the limits of Sanitary Standard for Drinking Water Quality (China, 2001). Conclusion A wider survey of HAAs in drinking water should be conducted throughout the nation to get adequate data and information, the ultimate aim of which is to control HAAs pollution and keep the balance between microbiological safety insurance and chemical risk control, minimize the formation of DBPs and ensure the safety of water supply at the same time. | HONGZHOU XIAO-JIANZHANG ZHAN-SHENGWANG | 2004 | Biomedical and Environmental Sciences2004，17，3： | 7 |
| 7 | LiNbO3-coated LiNi0.8Co0.1Mn0.1O2 cathode with high discharge capacity and rate performance for all-solid-state lithium battery显示文摘In order to obtain high power density,energy density and safe energy storage lithium ion batteries(LIB)to meet growing demand for electronic products,oxide cathodes have been widely explored in all-solidstate lithium batteries(ASSLB)using sulfide solid electrolyte.However,the electrochemical performances are still not satisfactory,due to the high interfacial resistance caused by severe interfacial instability between sulfide solid electrolyte and oxide cathode,especially Ni-rich oxide cathodes,in charge-discharge process.Ni-rich LiNi0.8Co0.1Mn0.1O2(NCM811)material at present is one of the most key cathode candidates to achieve the high energy density up to 300 Wh kg^-1 in liquid LIB,but rarely investigated in ASSLB using sulfide electrolyte.To design the stable interface between NCM811 and sulfide electrolyte should be extremely necessary.In this work,in view of our previous work,LiNbO3 coating with about 1 wt% content is adopted to improve the interfacial stability and the electrochemical performances of NCM811 cathode in ASSLB using Li10GeP2S12 solid electrolyte.Consequently,LiNbO3-coated NCM811 cathode displays the higher discharge capacity and rate performance than the reported oxide electrodes in ASSLB using sulfide solid electrolyte to our knowledge. | Xuelei Li Liubing Jin Dawei Song Hongzhou Zhang Xixi Shi Zhenyu Wang Lianqi Zhang Lingyun Zhu | 2020 | Journal of Energy Chemistry2020，29，1： | 7 |
| 8 | Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro显示文摘目的: Epigallocatechin-3-gallate (EGCG ) 是在绿茶的主要 polyphenolic 成分。这研究的目的是在人的结肠癌 SW620 房间的增长和移植上调查 EGCG 的效果。 | FangZhou HongZhou TingWang YuanMu BiaoWu Dong-linGuo Xian-meiZhang YingWu | 2012 | Acta Pharmacologica Sinica2012，33，1： | 7 |
| 9 | Wind impact on pollutant transport in a shallow estuary显示文摘A three-dimensional numerical model,EFDC(environmental fluid dynamics code)is applied to the Pamlico River Estuary(PRE)in eastern North Carolina of the United States to examine the wind impact on pollutant age distributions and residence time.A series of model experiments representing base case,remote-wind-induced water level set-up and local winds cases are conducted.Model results indicate that the pollutant mean age and the system residence time are functions of gravitational circulation in the PRE.The system responses to remote-wind-induced water level set-up are different in different portions of the PRE.Under such condition,dissolved substances in the upstream portion of the PRE have a younger age and shorter residence time(compared with the base case),by contrast,they have a older age and longer residence time in the downstream portion of the PRE.Upriver and downriver local winds appear to have opposite impacts on pollutant age distributions.The substances are retained much longer within the PRE under upriver wind than those under downriver wind.The model results also suggest that across-river winds may lead to longer residence time through enhanced turbulence mixing,which slows down the gravitational circulation in the PRE. | XU Hongzhou LIN Jing SHEN Jian WANG Dongxiao | 2008 | Acta Oceanologica Sinica2008，27，3： | 7 |
| 10 | Analysis of surface orange peel of aluminum-alloy automobile sheet by using of EBSD and X-ray diffraction显示文摘The formation cause of orange peel of aluminum-alloy automotive sheet after tensile deformation was analysed by using X-ray diffraction and electron back-scattered diffraction(EBSD).The test results showed that formation cause of surface orange peel after tensile deformation related to product texture and nonuniform deformation during the tensile process.The grain size has significant effect on deformation uniform and texture formation.Coarse grains were easy to produce nonuniform deformation and texture,which would produce surface orange peel after tensile deformation. | Ma Mingtu Sun Zhifu Wang Zhiwen Lu Hongzhou Zhou Mingbo | 2012 | Engineering Sciences2012，10，6： | 7 |
| 11 | A seventh-order model for dynamic response of an electro-hydraulic servo valve显示文摘In this paper, taking two degrees of freedom on the armature–flapper assembly into account, a seventh-order model is deduced and proposed for the dynamic response of a two-stage electro-hydraulic servo valve from nonlinear equations. These deductions are based on fundamental laws of electromagnetism, fluid, and general mechanics. The coefficients of the proposed seventhorder model are derived in terms of servo valve physical parameters and fluid properties explicitly.For validating the results of the proposed model, an AMESim simulation model based on physical laws and the existing low-order models validated by other researchers through experiments are used to compare with the seventh-order model. The results show that the seventh-order model can reflect the physical behavior of the servo valve more explicitly than the existing low-order models and it could provide guidance more easily for a linear control design approach and sensitivity analysis than the AMESim simulation model. | Liu Changhai Jiang Hongzhou | 2014 | Chinese Journal of Aeronautics2014，27，6： | 6 |
| 12 | An antiretroviral regimen containing 6 months of stavudine followed by long-term zidovudine for first-fine HIV therapy is optimal in resource-limited settings: a prospective, multicenter study in China显示文摘 | Li Taisheng Guo Fuping Li Yijia Zhang Chengda Han Yang Lye Wei He Yun Lu Hongzhou Xie Jing Huang Aiqiong Li Yanling Tang Xiaoping Wang Hui Zhang Tong Gao Guiju Lei Junkang Zhang Xiaoying Wu Xinhua Sun Yongtao Bai Jinsong Luo Ling Wang Huanlmg | 2014 | Chinese Medical Journal2014，，1： | 6 |
| 13 | Durability of neutralizing antibodies and T-cell response post SARS-CoV-2 infection显示文摘The ongoing pandemic of coronavirus disease 19(COVID-19)is caused by a newly discoveredβcoronavirus named severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).How long the adaptive immunity triggered by SARS-CoV-2 can last is of critical clinical relevance in assessing the probability of second infection and efficacy of vaccination.Here we examined,using ELISA,the IgG antibodies in serum specimens collected from 17 COVID-19 patients at 6–7 months after diagnosis and the results were compared to those from cases investigated 2 weeks to 2 months post-infection.All samples were positive for IgGs against the S-and N-proteins of SARS-CoV-2.Notably,14 samples available at 6–7 months post-infection all showed significant neutralizing activities in a pseudovirus assay,with no difference in blocking the cell-entry of the 614D and 614G variants of SARS-CoV-2.Furthermore,in 10 blood samples from cases at 6–7 months post-infection used for memory T-cell tests,we found that interferonγ-producing CD4+and CD8+cells were increased upon SARS-CoV-2 antigen stimulation.Together,these results indicate that durable anti-SARS-CoV-2 immunity is common in convalescent population,and vaccines developed from 614D variant may offer protection from the currently predominant 614D variant of SARS-CoV-2. | Yun Tan Feng Liu Xiaoguang Xu Yun Ling Weijin Huang Zhaoqin Zhu Mingquan Guo Yixiao Lin Ziyu Fu Dongguo Liang Tengfei Zhang Jian Fan Miao Xu Hongzhou Lu Saijuan Chen | 2020 | Frontiers of Medicine2020，14，6： | 6 |
| 14 | Thermodynamic Characteristic Study of a High-temperature Flow-rate Control Valve for Fuel Supply of Scramjet Engines显示文摘Thermodynamic characteristics are of great importance for the performance of a high-temperature flow-rate control valve,as high-temperature environment may bring problems,such as blocking of spool and increasing of leakage,to the valve.In this paper,a high-temperature flow-rate control valve,pilot-controlled by a pneumatic servo system is developed to control the fuel supply for scramjet engines.After introducing the construction and working principle,the thermodynamic mathematical models of the valve are built based on the heat transfer methods inside the valve.By using different boundary conditions,different methods of simulations are carried out and compared.The steady-state and transient temperature field distribution inside the valve body are predicted and temperatures at five interested points are measured.By comparing the simulation and experimental results,a reasonable 3D finite element analysis method is suggested to predict the thermodynamic characteristics of the high-temperature flow-rate control valve. | ZENG Wen TONG Zhizhong LI Songjing LI Hongzhou ZHANG Liang | 2012 | Chinese Journal of Aeronautics2012，25，4： | 6 |
| 15 | Thermally stable and highly efficient red-emitting Eu^(3+)-doped Cs3GdGe309 phosphors for WLEDs:non-concentration quenching and negative thermal expansion显示文摘Red phosphor materials play a key role in improving the lighting and backlit display quality of phosphor-converted white light-emitting diodes(pc-WLEDs).However,the development of a red phosphor with simultaneous high efficiency,excellent thermal stability and high colour purity is still a challenge.In this work,unique non-concentration quenching in solid-solution Cs_(3)Gd_(1-x)Ge_(3)O_(9):xEu^(3+)(CGGO:xEu^(3+))(x=0.1-1.0)phosphors is successfully developed to achieve a highly efficient red-emitting Cs_(3)EuGe_(3)0_(9)(CEGO)phosphor.Under the optimal 464 nm blue light excitation,CEGO shows a strong red emission at 611 nm with a high colour purity of 95.07%and a high internal quantum efficiency of 94%.Impressively,this red-emitting CEGO phosphor exhibits a better thermal stability at higher temperatures(175-250℃,>90%)than typical red K2SiF6:Mn^(4+)and Y203:Eu^(3+)phosphors,and has a remarkable volumetric negative thermal expansion(coefficient of thermal expansion,a=—5.06×10^(-5)/℃,25-250℃).By employing this red CEGO phosphor,a fabricated pc-WLED emits warm white light with colour coordinates(0.364,0.383),a high colour rendering index(CRI=89.7),and a low colour coordinate temperature(CCT=4508 K).These results indicate that this highly efficient red-emitting phosphor has great potential as a red component for pc-WLEDs,opening a new perspective for developing new phosphor materials. | Peipei Dang Guogang Li Xiaohan Yun Qianqian Zhang Dongjie Liu Hongzhou Lian Mengmeng Shang Jun Lin | 2021 | Light(Science & Applications)2021，10，2： | 6 |
| 16 | An inertial parameter identification method of eliminating system damping effect for a six-degree-of-freedom parallel manipulator显示文摘A new simple and effective inertial parameter identification method based on sinusoidal vibrations of a six-degree-of-freedom parallel manipulator is proposed. Compared with previously known identification algorithms, the advantages of the new approach are there is no need to design the excitation trajectory to consider the condition number of the observation matrix and the inertial matrix can be accurately defined regardless of the effect of viscous friction. In addition, the use of a sinusoidal exciting trajectory allows calculation of the velocities and accelerations from the measured position response. Simulations show that the new approach has acceptable tolerance of dry friction when using a simple coupling parameter modified formula. The experimental application to the hydraulically driven Stewart platform demonstrates the capability and efficiency of the proposed identification method. | Tian Tixian Jiang Hongzhou Tong Zhizhong He Jingfeng Huang Qitao | 2015 | Chinese Journal of Aeronautics2015，28，2： | 5 |
| 17 | A Soft Robotic Fish with Variable-stiffness Decoupled Mechanisms显示文摘 | Kangkang Li Hongzhou Jiang Siyu Wang Jianmin Yu | 2018 | Journal of Bionic Engineering2018，15，4： | 5 |
| 18 | Preheating Characteristics of Datong Coal in O2/CO2 and Air Atmospheres显示文摘Experimental studies were carried out to find the difference of preheating characteristics of Datong coal in O_2/CO_2 and air atmospheres by a circulating fluidized bed. It is found that pulverized coal could be both steadily preheated to above 800°C in the two different atmospheres, but the temperature distribution was more uniform along the riser in O_2/CO_2 atmosphere. During the preheating, the content of CO in the flue gas can reach 12.32% under the O_2/CO_2 atmosphere, far higher than that in air(5.94%). Simultaneously, the conversion rate of fixed carbon was higher in O_2/CO_2 atmosphere compared with that in air. It can be inferred the higher oxygen concentration and higher partial pressure of CO_2 have greatly accelerated the gasification reaction. The BET analysis indicated a number of large pores were transformed into micropores during the preheating progress, and the major contributors for overall pore volume of chars and specific surface area are the micro-pores and the mesopores with diameter ranging from 2 nm to 10 nm. The inner pore structure was more developed in O_2/CO_2 atmosphere. | ZHU Jianguo MA Hongzhou LIU Dianbin LI Jiarong | 2018 | Journal of Thermal Science2018，27，4： | 5 |
| 19 | Dent Resistance for Automobile Body Panels显示文摘Dent resistance of automobile body panels is an important property for automobile design and manufacture, but the study on this aspect is not still profound. This study is to summarize the testing methods and physical significations of static and dynamic dent resistance of automobile body panels combined with the author's study, and to analyze the dent behaviors in the round. Several influence factors on dent resistance are expatiated including the mechanical properties of materials, stress states after forming, bake hardening ability, modulus, methods of testing, and structure of specimens and so on. The automotive lightweight and application of high strength steel sheets and aluminum alloys sheets are analyzed, and the significance of testing of dent resistance, especially for dynamic dent resistance of auto-panels, and the finite element simulation analysis are emphasized. To explain the physical phenomenon of dent behaviors, the latest and concerned study results are also discussed. According to this study, a dent resistance test and evaluation standard of Society of Automotive Engineers of China for automotive body panel is presented and is being carried out, and an industry conference is hold to discuss the working-out of the standard, a primary schedule of this standard is confirmed now. The study can guide the further testing and study of dent resistant of auto-panels. | LU Hongzhou MA Mingm YOU Jianghai LI Zhigang | 2009 | Chinese Journal of Mechanical Engineering2009，22，6： | 5 |
| 20 | Ore-forming and Exploration Models of the Baguamiao Gold Deposit,Shaanxi Province显示文摘The Baguamiao superlarge gold deposit in Shaanxi Province is one of the typical cases in China that are hosted by sedimentary rocks. Explorers and researchers have discussed the gold mineralization enrichment conditions by studying sulphur, oxygen, carbon, silicon stable isotopes and mineralizing fluid features of the Baguamiao gold deposit and proposed a hydrothermal sedimentation-magmatic reconstructing gold mineralization model featuring multi-sources of ore-forming materials and multistage mineralizations. In addition, prospecting for 'Baguamiao-type' gold deposits was started in the Fengtai Basin and a great number of important prospecting targets such as Tonglinggou, Simaoling, Guoansi and Dachaigou were discovered. | GUO Jian LIU Ping ZHANG Wanye ZHU Huaping ZHU Hongzhou | 2000 | Acta Geologica Sinica(English Edition)2000，74，3： | 4 |
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