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| 1 | Colorectal cancer in patients under 50 years of age:A retrospective analysis of two institutions' experience显示文摘AIM:To investigate the epidemiological characteristics of colorectal cancer(CRC)in patients under 50 years of age across two institutions.METHODS:Records of patients under age 50 years of age who had CRC surgery over a 16 year period were assessed at two institutions.The following documents where reviewed:admission notes,operative notes,and discharge summaries.The main study variables included:age,presenting symptoms,family history,tumor location,operation,stage/differentiation of disease,and post operative complications.Stage of disease was classified according to the American Joint Committee on Cancer TNM staging system:tumor depth;node status;and metastases.RESULTS:CRC was found in 180 patients under age50 years(87 females,93 males;mean age 41.4±6.2years).Young patients accounted for 11.2%of cases during a 6 year period for which the full data set wasavailable.Eight percent had a 1stdegree and 12%a 2nd degree family CRC history.Almost all patients(94%)were symptomatic at diagnosis;common symptoms included:bleeding(59%),obstruction(9%),and abdominal/rectal pain(35%).Evaluation was often delayed and bleeding frequently attributed to hemorrhoids.Advanced stage CRC(Stage 3 or 4)was noted in 53%of patients.Most tumors were distal to the splenic flexure(77%)and 39%involved the rectum.Most patients(95%)had segmental resections;6 patients had subtotal/total colectomy.Poorly differentiated tumors were noted in 12%and mucinous lesions in 19%of patients of which most had Stage 3 or 4 disease.Twenty-two patients(13%)developed recurrence and/or progression of disease to date.Three patients(ages 42,42and 49 years)went on to develop metachronous primary colon cancers within 3 to 4 years of their initial resection.CONCLUSION:CRC was common in young patients with no family history.Young patients with symptoms merit a timely evaluation to avoid presentation with late stage CRC. | Elizabeth A Myers Daniel L Feingold Kenneth A Forde Tracey Arnell Joon Ho Jang Richard L Whelan | 2013 | World Journal of Gastroenterology2013，19，34： | 9 |
| 2 | Novel antigens for neurocys2 ticereosis: simp lemethod for p reparation and evaluation for serodiagnosis显示文摘 | ho A Plancarit A L iang MA | 1998 | Am J Trop hyg1998，59，2： | 1 |
| 3 | Poly(cyano-substituted diheteroareneethylene) as electrode material for electrochemical supercapacitors 显示文摘 | Fusalba F Ho H A Breau L | 2000 | Chem Mater2000，12，9： | 1 |
| 4 | Persistent genital human papillom avirus infection as a risk factor for persistent cervical dysplasia显示文摘 | Ho GY Burk RD Klein S et a l | 1995 | J Natl Cancer Inst1995，87，18： | 1 |
| 5 | Experimental focal segmental glomerulosclerosis in mice显示文摘 | CHEN A SHEU L F HO Y S | 1998 | Nephron1998，78，4： | 1 |
| 6 | Chemical synthesis and electrochemical properties of poly (cyano-substituted-diheteroareneethylene) as conducting polymers for electrochemical supercapacitors显示文摘 | SOUDAN P HO H A BR EAU L | 2001 | J Electrochemical Society2001，148，7： | 1 |
| 7 | Understanding the psychological motives behind microblogging显示文摘 | Qiu L Leung A K Ho J H | | 0，，： | 1 |
| 8 | Controlled synthesis and application of ZnO nanoparticles, nanorods and nanospheres indye-sensitized solar cells显示文摘 | Z L S Seow A S W Wong V Thavasi R Jose S Ramakrishna G W Ho | 2009 | Nanotechnology2009，，4： | 1 |
| 9 | Warm or cool, large or small? The challenge of thermal displays 显示文摘 | Jones L A Ho H | 2008 | IEEE Transactions on Haptics2008，1，1： | 1 |
| 10 | Chemical synthesis and electrochemical properties of poly(cyano-substituted- diheteroareneethylene) as conducting polymers for electrochemical supercapacitors 显示文摘 | Soudan P Ho H A Breau L | 2001 | J Electrochem Soc2001，148，7： | 1 |
| 11 | Human papillomavirus detection for cervical cancer prevention with polymerase chain reaction in self-collected samples显示文摘 | Lorenzato FR Singer A Ho L | 2002 | Am J Obstet Gynecol2002，186，： | 1 |
| 12 | Butorphanol: effect s of a prototypical agonist-antagonist analgesic on kappa-opioid receptors显示文摘 | Commiskey S Fan LW Ho IK et a l | 2005 | J Pharmacol Sci2005，98，： | 1 |
| 13 | Influence of dried Bacillus subdlis and Lactobacilli cultures on intestinal mlcrnflora and performance in broilers 显示文摘 | JIN L Z HO Y W ABDULLN A H | 1996 | Asian-Australasian Journal of Animal Science1996，9，： | 1 |
| 14 | Nanothoranostics-a review of rccent publications显示文摘 | Wang L S Chuang M C Ho J A | 2012 | Int J Nanomcdicine2012，7，： | 1 |
| 15 | Characteristics of carbonaceous aerosol in Pearl River Delta Region, China during winter period 显示文摘 | CAO J J LEE S C HO K F et a l | 2003 | Atmos Environ2003，，37： | 1 |
| 16 | Extracting,linking and integrating data from public sources:a financial case study显示文摘 | Burdick D Hernández M A Ho H Koutrika G Krishnamurthy R Popa L Sranoi I Vaithyanathan S Das S R | | 0，，03： | 1 |
| 17 | Vancomycin MIC creep in MRSA isolates from 1997 to 2008 in a healthcare region in Hong Kong显示文摘 | Ho P L Lo P Y Chow K H et a l | 2010 | J Infect2010，60，11： | 1 |
| 18 | Case report:parachordoma of soft tissues of the arm显示文摘 | Clabeaux J Ho Jnowski L Valente A | 2008 | Clin Orthop Relat Res2008，466，5： | 1 |
| 19 | Narcissism, extraversion and adolescents' self- presentation on Facebook显示文摘 | ONG E Y L ANG R P HO J C M e t a l | 2011 | Pets Individ Oil2011，50，2： | 1 |
| 20 | Long -term r i sk of incident v e r t e b r a 1 f r a c t u r e s 显示文摘 | Ca u 1 e y JA Ho c h b e r g MC L u i LY e t a 1 | | JAMA0，298，23： | 1 |
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