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| 1 | 内侧固定平台单髁置换术后的冠状面下肢力线是翻修的影响因素显示文摘膝关节单髁置换术(unicompartmental knee arthroplasty,UKA)后患者冠状面的下肢力线被认为是影响手术长期疗效的一个重要因素,但关于最佳的UKA术后下肢力线还没有形成明确共识。一些研究主张术后下肢力线应保持在中立位,而另一些研究认为即使术后下肢力线存在10°的内翻也可获得良好的临床效果。 | Sean E Slaven John P Cody Robert A Sershon Henry Ho Robert H Hopper Jr Kevin B Fricka 李亚坤(整理) 张民(整理) | 2020 | 实用骨科杂志2020，26，12： | 15 |
| 2 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 3 | Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters. | V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun | 2003 | World Journal of Gastroenterology2003，9，10： | 5 |
| 4 | Identification of telmisartan as a unique angiotensin Ⅱ receptor antagonist with selective PPARγ-modulating activity 显示文摘 | BENSON S C PERSHADSINGH H A HO C I | 2004 | Hypertension2004，43，5： | 1 |
| 5 | Regulation of matrix metalloproteinases (MMP 2, 3, -9, and 13) by interleukin-1 and interleukin-6 in mouse calvaria: association of MMP induction with bone resorption显示文摘 | Kusano K Miyaura C Inada M Tamura T ho A Nagase H | 1998 | Endocrinology1998，139，： | 1 |
| 6 | Adaptive fuzzy sliding mode control with chattering elimination for nonlinear SISO systems 显示文摘 | Ho H F Wong Y K Rad A B et | 2009 | Simulation Modelling Practice and Theory2009，17，7： | 1 |
| 7 | Temporary placement of fully covered self expandable metal stents in benign biliary strictures: Midterm evaluation (with video) 显示文摘 | MAHAJAN A HO H SAUER B | 2009 | Gastrointest Endosc2009，70，2： | 1 |
| 8 | Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals显示文摘 | Scheid J F Mouquet H Feldhahn N Seaman M S Velinzon K Pietzsch J Ott R G Anthony R M Zebroski H Hurley A Phogat A Chakrabarti B Li Y Connors M Pereyra F Walker B D Wardemann H Ho D Wyatt R T Mascola J R Ravetch J V Nussenzweig M C | 2009 | Nature2009，458，7238： | 1 |
| 9 | Poly(cyano-substituted diheteroareneethylene) as electrode material for electrochemical supercapacitors 显示文摘 | Fusalba F Ho H A Breau L | 2000 | Chem Mater2000，12，9： | 1 |
| 10 | Circulating miR-210 as a novel hypoxia marker in pancreatic cancer显示文摘 | Ho A S Huang X Cao H B | | 0，，02： | 1 |
| 11 | Clinical and radiological comparison of posterolateral fusion and posterior interbody fusion techniques for multilevel lumbar spinal stabilization in manual workers显示文摘 | Aygu n H Cakar A HO seyino?lu N | 2014 | Asian Spine J2014，8，5： | 1 |
| 12 | Chemical synthesis and electrochemical properties of poly (cyano-substituted-diheteroareneethylene) as conducting polymers for electrochemical supercapacitors显示文摘 | SOUDAN P HO H A BR EAU L | 2001 | J Electrochemical Society2001，148，7： | 1 |
| 13 | Synthesis,chemical polymerization and electrochemical properties of low band gap conducting polymers for use in suercapacitors 显示文摘 | Soudan P Lucas P Ho H A | 2001 | J Mater Chem2001，11，3： | 1 |
| 14 | Understanding the psychological motives behind microblogging显示文摘 | Qiu L Leung A K Ho J H | | 0，，： | 1 |
| 15 | The natu- ral history of idiopathic subfoveal choroidal neovas- cularization显示文摘 | Ho A C YANN H A PISICANO K | 1995 | Ophthalmology1995，102，5： | 1 |
| 16 | Biometry and primary angle-closure glaucoma among Chi- nese,white, and black populations 显示文摘 | Congdon NG Youlin Q Quigley H Hung PT Wang TH Ho TC et a/ | 1997 | Ophthalmology1997，104，9： | 1 |
| 17 | Optical detection of DNA and proteins with cationic polythiophenes 显示文摘 | Ho H A Najari A Leclerc M | 2007 | Acc Chem Res2007，41，2： | 1 |
| 18 | Warm or cool, large or small? The challenge of thermal displays 显示文摘 | Jones L A Ho H | 2008 | IEEE Transactions on Haptics2008，1，1： | 1 |
| 19 | Chemical synthesis and electrochemical properties of poly(cyano-substituted- diheteroareneethylene) as conducting polymers for electrochemical supercapacitors 显示文摘 | Soudan P Ho H A Breau L | 2001 | J Electrochem Soc2001，148，7： | 1 |
| 20 | Spread of drug-resist- ant pulmonary tuberculosis in Estonia显示文摘 | Kruvmer A Ho{{iier SE Sillastu H | 2001 | J Clin Microbiol2001，39，9： | 1 |
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