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	题名	作者	年代	出处	被引量
1	Personalising pancreas cancer treatment:When tissue is the issue显示文摘The treatment of advanced pancreatic cancer has not moved much beyond single agent gemcitabine until recently when protocols such as FOLFIRINOX(fluorouracil,leucovorin,irinotecan and oxaliplatin)and nab-paclitaxelgemcitabine have demonstrated some improved outcomes.Advances in technology especially in massively parallel genome sequencing has progressed our understanding of the biology of pancreatic cancer especially the candidate signalling pathways that are involved in tumourogenesis and disease course.This has allowed identification of potentially actionable mutations that may be targeted by new biological agents.The heterogeneity of pancreatic cancer makes tumour tissue collection important with the aim of being able to personalise therapies for the individual as opposed to a one size fits all approach to treatment of the condition.This paper reviews the developments in this area of translational research and the ongoing clinical studies that will attempt to move this into the everyday oncology practice.	Katrin M Sjoquist Venessa T Chin Lorraine A Chantrill Chelsie O'Connor Chris Hemmings David K Chang Angela Chou Marina Pajic Amber L Johns Adnan M Nagrial Andrew V Biankin Desmond Yip	2014	World Journal of Gastroenterology2014，20，24：	2
2	Antimicrobial activity of polysaccharide films containing essential oils显示文摘	Sanchez-González L Cháler M Hemández M		0，，08：	1
3	Investigating the role of the brain-derived neurotrophic factor (BDNF) va166met variant in obsessive-compulsive disorder (OCD) 显示文摘	HEMMINGS S M KINNEAR C J van der MERWE L et al	2008	World J Biol Psychiatry2008，9，2：	1
4	Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up显示文摘ObjectiveTo 评估立即的 transcatheter 在有严重、征兆的大动脉的狭窄的很老的病人的大动脉的阀门培植(TAVI ) 结果和中期的后续(作为).MethodsThis multicenter,观察、未来的学习在三所医院里被执行。我们包括了连续很老(>85 年) 病人与作为严重由 TAVI 对待。主要端点是在包括的二 years.ResultsThe 研究从任何原因评估死亡率有一个平均数的 160 个连续病人 87 ± 变老;2.1 年(从 85 ~ 94 年的范围) 和 18.8%± 的吝啬的逻辑 EuroSCORE;11.2% 与 57 (35.6%) 病人得分 ≥20% 。程序的成功率是 97.5% ,与 25 (15.6%) 与主要流血经历尖锐复杂并发症的病人(最经常) 。全球死亡率在住院期间是 8.8%(n = 14 ) 并且 30 天的死亡率是 10%(n = 16 ) 。中部在时期上面列在后面是 252.24 ±232.17 天。在后续时期期间, 28 (17.5%) 病人们死了(他们中的 17 个由于心脏的原因) 。估计的二年全面、心脏的幸存率使用 Kaplan-Meier 方法分别地是 71% 和 86.4% 。比例的危险回归给看了的考克斯可变 EuroSCORE ≥20 是与全面 mortality.ConclusionsTAVI 联系的唯一的变量在很老的病人的一张选择人口安全、有效。我们的调查结果支持在病人的这个复杂的组的这个新过程的采纳。	Isaac Pascual Antonio J Mu oz-García Diego López-Otero Pablo Avanzas Manuel F Jimenez-Navarro Belén Cid-Alvarez Raquel del Valle Juan H Alonso-Briales Raimundo Ocaranza-Sanchez José M Hemández Ramiro Trillo-Nouche César Morís	2015	Journal of Geriatric Cardiology2015，12，4：	1
5	The future is now: Model‐based clinical trial design for Alzheimer’s disease显示文摘	K Romero K Ito JA Rogers D Polhamus R Qiu D Stephenson R Mohs R Lalonde V Sinha Y Wang D Brown M Isaac S Vamvakas R Hemmings L Pani LJ Bain B Corrigan	2015	Clin. Pharmacol. Ther2015，，3：	1
6	BDNF Val66Met andDRD2 TaqlA polymorphisms interact to influence PTSD symptom se-verity :a preliminary investigation in a South African population显示文摘	Hemmings S Martin L Klopper M	2013	Prog Neuropsychopharmacol Biol Psychiatry2013，40，：	1
7	High-performance liquid chromatographic determination of chitin in the snow crab, chionoecetes opilio 显示文摘	Pun' m Crespo M O Vilasoa Mart' mez M L' opez Hem' andez J	2006	Journal of Chromatography A2006，1116，：	1
8	2012, Determination of Dinotefuran in Pepper Using Liquid Chromatography: Contribution to Safety Evaluation 显示文摘	HEM L ABDEI-ATY A M PARK J H	2012	Journal of the Korean Society for Applied Biological Chemistry2012，55，6：	1
9	Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse of Alzheimer disease显示文摘	Hemming M L Selkoe D J Farris W	2007	Neurobiology of Disease2007，，：	1
10	Factors Influencing Suc- cessful Brand Extension显示文摘	Hem L E De Chernatong L Iversen N M	2003	Journal of Marketing Management2003，19，2：	1
11	Epimerization of benzylpenicilloic acid in alkaline media显示文摘	Ghebre-Sellassie I Hem S L Knevel A M	1984	J Pharm Sci1984，73，1：	1
12	How to develop a destination brand logo: a qualitative and quantitative approach 显示文摘	Hem L F Iversen N M	2004	Scandinavian Journal of Hospitality and Tourism2004，4，2：	1
13	Anti-C, trachomatis IgG antibodies levels in serum to identify infertility caused by tubal damage显示文摘	Hem 6 ndez-Trejo M L 6 pez-Hurtado M Arteaga-Troncoso G	2009	Rev Invest Clin2009，61，1：	1
14	Factors influencing successful brand extensions显示文摘	Hem L E DE Cherntony L Iversen N M		0，，718：	1
15	Provenance Associations as Core Values of Place Umbrella Brands : A Framework of Characteristics 显示文摘	Iversen M L E Hem	2008	Euro- pean Journal of Marketing2008，42，56：	1
16	Factors Influencing Successful Brand Extensions显示文摘	Hem L E de Chernatony L Iversen N M	2003	Journal of Mar- keting Management2003，19，78：	1
17	Synthesis of Fluorinated Block Copolymer and Their Application as Novel Polymerization Surfactants in Supercritical Carbon Dioxide显示文摘	Hems W P van Nunen J L M	1997	Chem Commun (Cambridge)1997，18，：	1
18	Transfer of brand equity in brand extensions:The importance of brand loyalty显示文摘	Hem L E and Iversen N M	2003	Advances in Consumer Research2003，30，：	1
19	Determination of dinotefuran in pepper using liquid chromatography:contribution to safety evaluation显示文摘	HEM L EL-ATY A M A PARK J H	2012	J Korean Soc Appl Biol Chem2012，55，6：	1
20	Reuseofwaste materials as growing media for ornamental plants 显示文摘	Hem ndez-Apaolaza L Gasc A M Gasc Jos M	2005	Bioresource Technology2005，96，：	1

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